Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 2 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Xenon Pharmaceuticals Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 290
- +49 vs. Q4 2025
- Shares held
- 100.2M
- +16.7M (+20.0%) vs. Q4 2025
- Total value
- $5.80B
- +$2.06B (+55.0%) vs. Q4 2025
- New holders
- 82
- 123 more added
- Sold out
- 33
- 60 more reduced
4 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| AQR Capital Management LLC | 7,279 | $423.3K | 0.00% | +7,279 | New |
| Ameritas Investment Partners, Inc. | 7,138 | $415.1K | 0.01% | +970+15.7% | Added |
| Great West Life Assurance Co | 7,024 | $411.0K | 0.00% | 00.0% | Unchanged |
| Advisors Asset Management, Inc. | 6,961 | $404.8K | 0.01% | −1,051−13.1% | Reduced |
| Oxford Asset Management LLP | 6,884 | $400.3K | 0.16% | −495−6.7% | Reduced |
| PenderFund Capital Management Ltd. | 6,850 | $398.3K | 0.06% | 00.0% | Unchanged |
| Bridgefront Capital, LLC | 6,564 | $381.7K | 0.09% | +6,564 | New |
| Longaeva Partners L.P. | 6,250 | $363.4K | 0.02% | +6,250 | New |
| Principal Financial Group Inc | 6,244 | $363.1K | 0.00% | +1,756+39.1% | Added |
| Toroso Investments, LLC | 6,225 | $362.0K | 0.00% | +6,225 | New |
| Virtus Investment Advisers, Inc. | 6,188 | $359.8K | 0.10% | +151+2.5% | Added |
| Headlands Technologies LLC | 6,120 | $355.9K | 0.04% | +6,120 | New |
| Tower Research Capital LLC (TRC) | 6,105 | $355.0K | 0.01% | +2,873+88.9% | Added |
| Letson Investment Management, Inc. | 6,000 | $348.9K | 0.13% | 00.0% | Unchanged |
| STRS Ohio | 5,700 | $331.5K | 0.00% | +4,400+338.5% | Added |
| DRW Securities, LLC | 5,461 | $317.6K | 0.02% | +5,461 | New |
| CAPROCK Group, Inc. | 5,291 | $307.7K | 0.01% | +222+4.4% | Added |
| Ensign Peak Advisors, Inc | 5,194 | $302.0K | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 5,000 | $290.8K | 0.00% | 00.0% | Unchanged |
| LPL Financial LLC | 4,964 | $288.7K | 0.00% | +4,964 | New |
| Citizens Financial Group Inc | 4,963 | $288.6K | 0.00% | −37−0.7% | Reduced |
| Swiss Life Asset Management Ltd | 4,847 | $281.9K | 0.00% | +4,847 | New |
| CIBC Bancorp USA Inc. | 4,349 | $252.9K | 0.00% | +4,349 | New |
| Mirae Asset Global Investments Co., Ltd. | 4,339 | $252.3K | 0.00% | +584+15.6% | Added |
| Oppenheimer Asset Management Inc. | 4,325 | $251.5K | 0.00% | +4,325 | New |
| Snowden Capital Advisors LLC | 4,223 | $245.6K | 0.01% | +4,223 | New |
| PSP Research LLC | 4,200 | $244.2K | 0.17% | −7,478−64.0% | Reduced |
| FNY Investment Advisers, LLC | 4,200 | $244.0K | 0.11% | +4,200 | New |
| Aigen Investment Management, LP | 4,123 | $239.8K | 0.06% | +4,123 | New |
| Cetera Investment Advisers | 3,624 | $210.7K | 0.00% | +3,624 | New |
| Seeds Investor LLC | 3,423 | $203.2K | 0.03% | +3,423 | New |
| Jane Street Group, LLC | 3,468 | $201.7K | 0.00% | +3,468 | New |
| Caitong International Asset Management Co., Ltd | 3,330 | $193.6K | 0.04% | +2,105+171.8% | Added |
| Eurizon Capital SGR S.p.A. | 2,649 | $147.9K | 0.00% | +2,649 | New |
| Jones Financial Companies LLLP | 2,399 | $130.7K | 0.00% | +2,249+1,499.3% | Added |
| IFP Advisors, Inc | 1,871 | $108.8K | 0.00% | −6−0.3% | Reduced |
| GF Fund Management Co. Ltd. | 1,735 | $100.9K | 0.00% | +218+14.4% | Added |
| State of Wyoming | 1,381 | $80.3K | 0.01% | −120−8.0% | Reduced |
| Axiom Investment Management LLC | 1,000 | $58.1K | 0.04% | +1,000 | New |
| SBI Securities Co., Ltd. | 988 | $57.5K | 0.00% | +987+98,700.0% | Added |
| Nisa Investment Advisors, LLC | 951 | $55.3K | 0.00% | +27+2.9% | Added |
| Kemnay Advisory Services Inc. | 764 | $44.4K | 0.01% | +641+521.1% | Added |
| Ronald Blue Trust, Inc. | 745 | $43.3K | 0.00% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 677 | $39.0K | 0.00% | +677 | New |
| Sterling Capital Management LLC | 560 | $32.6K | 0.00% | +69+14.1% | Added |
| Bayforest Capital Ltd | 555 | $32.3K | 0.04% | +555 | New |
| Signaturefd, LLC | 553 | $32.2K | 0.00% | +80+16.9% | Added |
| CWM, LLC | 510 | $29.7K | 0.00% | +144+39.3% | Added |
| Vanguard Global Advisers, LLC | 494 | $28.7K | 0.00% | +494 | New |
| MAI Capital Management | 392 | $22.8K | 0.00% | +131+50.2% | Added |
| Advisor Group Holdings, Inc. | 389 | $22.6K | 0.00% | +70+21.9% | Added |
| GAMMA Investing LLC | 373 | $21.7K | 0.00% | +109+41.3% | Added |
| Zions Bancorporation, National Association | 305 | $17.7K | 0.00% | +70+29.8% | Added |
| Huntington National Bank | 288 | $16.7K | 0.00% | +288 | New |
| Basecamp Wealth Advisors LLC | 280 | $16.3K | 0.00% | +280 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 276 | $16.0K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 272 | $15.8K | 0.00% | +97+55.4% | Added |
| J.Safra Asset Management Corp | 268 | $15.6K | 0.00% | +181+208.0% | Added |
| National Bank of Canada | 235 | $13.7K | 0.00% | +45+23.7% | Added |
| Rockefeller Capital Management L.P. | 200 | $11.6K | 0.00% | −900−81.8% | Reduced |
| Farther Finance Advisors, LLC | 189 | $10.7K | 0.00% | −869−82.1% | Reduced |
| Rossby Financial, LCC | 181 | $10.3K | 0.00% | +134+285.1% | Added |
| Quantbot Technologies LP | 162 | $9.42K | 0.00% | +162 | New |
| Parallel Advisors, LLC | 152 | $8.84K | 0.00% | +5+3.4% | Added |
| SMA Capital LLC | 139 | $8.08K | 0.00% | +139 | New |
| TD Waterhouse Canada Inc. | 130 | $7.33K | 0.00% | +130 | New |
| Rothschild Investment LLC | 126 | $7.33K | 0.00% | +15+13.5% | Added |
| Danske Bank A/S | 100 | $5.82K | 0.00% | −700−87.5% | Reduced |
| Bell Investment Advisors, Inc | 100 | $5.82K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 77 | $4.48K | 0.00% | −135−63.7% | Reduced |
| Larson Financial Group LLC | 52 | $3.02K | 0.00% | +50+2,500.0% | Added |
| Root Financial Partners, LLC | 40 | $2.33K | 0.00% | +40 | New |
| Allworth Financial LP | 38 | $2.21K | 0.00% | −78−67.2% | Reduced |
| Golden State Equity Partners | 35 | $2.04K | 0.00% | +35 | New |
| CVA Family Office, LLC | 33 | $1.92K | 0.00% | 00.0% | Unchanged |
| Twin Peaks Wealth Advisors, LLC | 32 | $1.86K | 0.00% | +32 | New |
| Parkside Financial Bank & Trust | 30 | $1.75K | 0.00% | 00.0% | Unchanged |
| First Horizon Corp | 24 | $1.40K | 0.00% | +24 | New |
| Covestor Ltd | 10 | $1.00K | 0.00% | −237−96.0% | Reduced |
| Hantz Financial Services, Inc. | 25 | $1.00K | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 17 | $989 | 0.00% | 00.0% | Unchanged |
| Massmutual Trust Co FSB | 17 | $989 | 0.00% | +6+54.5% | Added |
| Park Place Capital Corp | 16 | $930 | 0.00% | 00.0% | Unchanged |
| UMA Financial Services, Inc. | 13 | $756 | 0.00% | 00.0% | Unchanged |
| Smartleaf Asset Management LLC | 12 | $667 | 0.00% | −4−25.0% | Reduced |
| WPG Advisers, LLC | 9 | $523 | 0.00% | +9 | New |
| Pinnacle Wealth Planning Services, Inc. | 4 | $233 | 0.00% | +4 | New |
| Hughes Financial Services, LLC | 4 | $233 | 0.00% | +4 | New |
| Keating Financial Advisory Services, Inc. | 2 | $116 | 0.00% | +2 | New |
| TFC Financial Management | 1 | $59 | 0.00% | +1 | New |
| Dimensional Fund Advisors LP | 0 | $0 | 0.00% | −452,147−100.0% | Sold out |
| Deep Track Capital, LP | 0 | $0 | 0.00% | −366,435−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −259,320−100.0% | Sold out |
| Perceptive Advisors LLC | 0 | $0 | 0.00% | −200,791−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −173,882−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −162,551−100.0% | Sold out |
| Moore Capital Management, LP | 0 | $0 | 0.00% | −140,000−100.0% | Sold out |
| Assenagon Asset Management S.A. | 0 | $0 | 0.00% | −119,186−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −114,826−100.0% | Sold out |
| Squadron Capital Management LLC | 0 | $0 | 0.00% | −105,551−100.0% | Sold out |