Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
Holders of 5% or more of XENE
Holders whose latest Schedule 13D or 13G filing reports 5% or more of Xenon Pharmaceuticals Inc., largest stake first. The change is against the holder's previous filing.
| Holder | Latest form | Stake | Change | First filed | Latest filing | Filing |
|---|---|---|---|---|---|---|
| FMR LLC | 13G/A | 10.30%9.96M shares | +0.40 ppfrom 9.90% | Feb 8, 20215 filings | Aug 7, 2026 | SEC |
| Avoro Capital Advisors LLC | 13G/A | 6.26%5.78M shares | – | Feb 12, 20212 filings | May 15, 2026 | SEC |
| BlackRock, Inc. | 13G | 6.20%4.76M shares | New | Jul 17, 20251 filing | Jul 17, 2025 | SEC |
Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.
13D and 13G filings
17 Schedule 13D and 13G filings on Xenon Pharmaceuticals Inc., newest first, including old-format filings without a stake.
| Filed (ET) | Filer | Form | Stake | Change | Event date | Filing |
|---|---|---|---|---|---|---|
| Aug 13, 20264:08 PM ET | Wellington Management Group LLPand 2 others | 13G/A | 1.50%1.43M shares | −4.70 ppfrom 6.20%Below 5% | Jun 30, 2026 | SEC |
| Aug 7, 202611:04 AM ET | FMR LLCand 1 other | 13G/A | 10.30%9.96M shares | +0.40 ppfrom 9.90% | Jul 31, 2026 | SEC |
| Aug 6, 202610:43 AM ET | FMR LLCand 1 other | 13G/A | 9.90%9.60M shares | −1.60 ppfrom 11.50% | Jun 30, 2026 | SEC |
| May 15, 202611:23 AM ET | Janus Henderson Group PLC | 13G/A | 4.50%4.18M shares | −0.60 ppfrom 5.10%Below 5% | Mar 31, 2026 | SEC |
| May 15, 20268:17 AM ET | Avoro Capital Advisors LLCand 1 other | 13G/A | 6.26%5.78M shares | – | Mar 31, 2026 | SEC |
| May 15, 20267:06 AM ET | Driehaus Capital Management LLC | 13G/A | 4.87%4.49M shares | –Below 5% | Dec 31, 2025 | SEC |
| Feb 10, 202611:23 AM ET | Wellington Management Group LLPand 3 others | 13G | 6.20%4.76M shares | +3.40 ppfrom 2.80% | Dec 31, 2025 | SEC |
| Nov 14, 202510:29 AM ET | Janus Henderson Group PLC | 13G | 5.10%3.94M shares | New | Sep 30, 2025 | SEC |
| Aug 12, 202510:34 AM ET | Wellington Management Group LLPand 2 others | 13G/A | 2.80%2.17M shares | –Below 5% | Jun 30, 2025 | SEC |
| Aug 6, 202512:19 PM ET | FMR LLCand 1 other | 13G/A | 11.50%8.82M shares | +1.20 ppfrom 10.30% | Jun 30, 2025 | SEC |
| Jul 17, 20257:44 PM ET | BlackRock, Inc. | 13G | 6.20%4.76M shares | New | Jun 30, 2025 | SEC |
| Mar 7, 202510:01 AM ET | FMR LLCand 1 other | 13G/A | 10.30%7.85M shares | – | Feb 28, 2025 | SEC |
| Feb 16, 2021 | Biotechnology Value Fund L P | 13G/AOld format | – | – | – | SEC |
| Feb 12, 2021 | OrbiMed Advisors LLC | 13G/AOld format | – | – | – | SEC |
| Feb 12, 2021 | Avoro Capital Advisors LLC | 13G/AOld format | – | – | – | SEC |
| Feb 11, 2021 | Adage Capital Partners GP, L.L.C. | 13G/AOld format | – | – | – | SEC |
| Feb 8, 2021 | FMR LLC | 13GOld format | – | New | – | SEC |
Form 144: proposed insider sales
Notices from officers, directors and other affiliates planning to sell Xenon Pharmaceuticals Inc. shares.
No Form 144 notices for Xenon Pharmaceuticals Inc. are on file.