Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 315
- +27 vs. Q1 2026
- Shares held
- 101.1M
- +4.90M (+5.1%) vs. Q1 2026
- Total value
- $6.10B
- +$529.0M (+9.5%) vs. Q1 2026
- New holders
- 49
- 126 more added
- Sold out
- 22
- 87 more reduced
2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.81B |
| Q4 2025 | 246 | $3.79B |
| Q3 2025 | 219 | $3.44B |
| Q2 2025 | 206 | $2.61B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.99B |
| Q2 2024 | 213 | $2.92B |
| Q1 2024 | 220 | $3.24B |
| Q4 2023 | 204 | $3.37B |
| Q3 2023 | 181 | $2.14B |
| Q2 2023 | 175 | $2.44B |
| Q1 2023 | 163 | $2.43B |
| Q4 2022 | 159 | $2.47B |
| Q3 2022 | 154 | $2.11B |
| Q2 2022 | 151 | $1.74B |
| Q1 2022 | 132 | $1.51B |
| Q4 2021 | 130 | $1.57B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $702.6M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 9,647,998 | $582.4M | 0.03% | −1,170,493−10.8% | Reduced |
| BlackRock, Inc. | 7,522,482 | $454.1M | 0.01% | +1,882,364+33.4% | Added |
| Avoro Capital Advisors LLC | 5,777,777 | $348.7M | 3.13% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 4,570,556 | $275.9M | 0.78% | +165,244+3.8% | Added |
| Driehaus Capital Management LLC | 4,418,557 | $266.7M | 1.55% | −73,096−1.6% | Reduced |
| Jupiter Topco LLC | 4,186,519 | $252.7M | 0.10% | +4,186,519 | New |
| Price T Rowe Associates Inc | 3,248,219 | $196.1M | 0.02% | +1,918,628+144.3% | Added |
| JPMorgan Chase & Co | 2,617,360 | $157.4M | 0.01% | +693,750+36.1% | Added |
| Capital International Investors | 2,361,639 | $142.5M | 0.03% | −313,088−11.7% | Reduced |
| T. Rowe Price Investment Management, Inc. | 2,168,581 | $130.9M | 0.09% | +1,216,626+127.8% | Added |
| State Street Corp | 1,969,629 | $118.9M | 0.00% | +249,096+14.5% | Added |
| Two Sigma Investments, LP | 1,642,848 | $99.2M | 0.07% | +1,036,763+171.1% | Added |
| Deerfield Management Company, L.P. (Series C) | 1,615,696 | $97.5M | 1.02% | 00.0% | Unchanged |
| Affinity Asset Advisors, LLC | 1,595,000 | $96.3M | 4.71% | −80,000−4.8% | Reduced |
| Westfield Capital Management Co LP | 1,507,294 | $91.0M | 0.30% | +105,811+7.5% | Added |
| Alliancebernstein L.P. | 1,562,276 | $90.8M | 0.03% | +158,979+11.3% | Added |
| Franklin Resources Inc | 1,437,712 | $86.8M | 0.02% | +157,135+12.3% | Added |
| Wellington Management Group LLP | 1,425,492 | $86.0M | 0.01% | −3,404,149−70.5% | Reduced |
| Citadel Advisors LLC | 1,401,242 | $84.6M | 0.05% | −1,251,748−47.2% | Reduced |
| Geode Capital Management, LLC | 1,370,114 | $82.7M | 0.00% | +277,182+25.4% | Added |
| Siren, L.L.C. | 1,318,564 | $79.6M | 1.62% | 00.0% | Unchanged |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,290,731 | $77.9M | 0.08% | −51,297−3.8% | Reduced |
| Pictet Asset Management Holding SA | 1,187,723 | $71.6M | 0.07% | +508,014+74.7% | Added |
| Braidwell LP | 1,131,452 | $68.3M | 2.53% | −207,000−15.5% | Reduced |
| Nuveen, LLC | 993,126 | $59.9M | 0.01% | +743,090+297.2% | Added |
| Invesco Ltd. | 903,458 | $54.5M | 0.00% | +844,355+1,428.6% | Added |
| OrbiMed Advisors LLC | 892,471 | $53.9M | 1.02% | −167,500−15.8% | Reduced |
| Caligan Partners LP | 889,944 | $53.7M | 2.59% | −503,083−36.1% | Reduced |
| American Century Companies Inc | 884,319 | $53.4M | 0.02% | +205,005+30.2% | Added |
| Federated Hermes, Inc. | 883,737 | $53.3M | 0.08% | −88,500−9.1% | Reduced |
| Capital World Investors | 862,775 | $52.1M | 0.01% | +22,703+2.7% | Added |
| Goldman Sachs Group Inc | 773,625 | $46.7M | 0.00% | +3,750+0.5% | Added |
| Vanguard Portfolio Management LLC | 749,651 | $45.2M | 0.00% | +206,589+38.0% | Added |
| Vestal Point Capital, LP | 700,000 | $42.3M | 0.99% | +60,100+9.4% | Added |
| Alyeska Investment Group, L.P. | 697,692 | $42.1M | 0.11% | −601,777−46.3% | Reduced |
| Marshall Wace, LLP | 689,342 | $41.6M | 0.04% | +689,342 | New |
| Rock Springs Capital Management LP | 683,907 | $41.3M | 2.01% | −79,113−10.4% | Reduced |
| Northern Trust Corp | 671,566 | $40.5M | 0.00% | +143,783+27.2% | Added |
| Panagora Asset Management Inc | 664,031 | $40.1M | 0.12% | +664,031 | New |
| First Turn Management, LLC | 600,200 | $36.2M | 3.88% | −186,644−23.7% | Reduced |
| Tudor Investment Corp Et Al | 545,387 | $32.9M | 0.14% | +49,796+10.0% | Added |
| Loomis Sayles & Co L P | 527,273 | $31.8M | 0.04% | −37,624−6.7% | Reduced |
| Octagon Capital Advisors LP | 490,000 | $29.6M | 2.71% | 00.0% | Unchanged |
| Novo Holdings A/S | 485,438 | $29.3M | 1.70% | 00.0% | Unchanged |
| Candriam Luxembourg S.C.A. | 462,768 | $27.9M | 0.13% | −13,726−2.9% | Reduced |
| TimesSquare Capital Management, LLC | 451,593 | $27.3M | 0.40% | +92,300+25.7% | Added |
| Logos Global Management LP | 450,000 | $27.2M | 1.17% | 00.0% | Unchanged |
| Trails Edge Capital Partners, LP | 440,000 | $26.6M | 4.22% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 421,518 | $25.4M | 0.00% | +25,380+6.4% | Added |
| Algert Global LLC | 419,773 | $25.3M | 0.30% | +155,573+58.9% | Added |
| Standard Life Aberdeen plc | 408,736 | $24.7M | 0.03% | −201,193−33.0% | Reduced |
| Morgan Stanley | 406,257 | $24.5M | 0.00% | −67,502−14.2% | Reduced |
| Fiera Capital Corp | 405,638 | $24.5M | 0.09% | −303,891−42.8% | Reduced |
| Bank of America Corp | 404,067 | $24.4M | 0.00% | +138,800+52.3% | Added |
| Parkman Healthcare Partners LLC | 397,379 | $24.0M | 2.46% | −99,656−20.1% | Reduced |
| Nicholas Investment Partners, LP | 395,844 | $23.9M | 1.35% | +148,743+60.2% | Added |
| Millennium Management LLC | 376,777 | $22.7M | 0.02% | +174,992+86.7% | Added |
| UBS Asset Management Americas Inc | 374,748 | $22.6M | 0.00% | −418−0.1% | Reduced |
| Baker Bros. Advisors LP | 370,208 | $22.3M | 0.11% | 00.0% | Unchanged |
| Jones Hill Capital LP | 367,900 | $22.2M | 4.72% | +367,900 | New |
| Ameriprise Financial Inc | 318,548 | $19.2M | 0.00% | +239,643+303.7% | Added |
| Man Group plc | 310,617 | $18.7M | 0.03% | +310,617 | New |
| Adage Capital Partners GP, L.L.C. | 300,000 | $18.1M | 0.03% | −170,000−36.2% | Reduced |
| Soleus Capital Management, L.P. | 267,000 | $16.1M | 0.56% | −25,000−8.6% | Reduced |
| Jump Financial, LLC | 260,730 | $15.7M | 0.14% | +104,954+67.4% | Added |
| DAFNA Capital Management LLC | 250,772 | $15.1M | 2.89% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 249,473 | $15.1M | 0.00% | +60,393+31.9% | Added |
| State of Wisconsin Investment Board | 248,821 | $15.0M | 0.03% | −5,662−2.2% | Reduced |
| Nan Fung Trinity (HK) Ltd | 247,765 | $15.0M | 1.48% | 00.0% | Unchanged |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 238,600 | $14.4M | 0.33% | 00.0% | Unchanged |
| Allspring Global Investments Holdings, LLC | 234,412 | $14.1M | 0.02% | −11,894−4.8% | Reduced |
| Redmile Group, LLC | 229,374 | $13.8M | 0.93% | −33,300−12.7% | Reduced |
| Schonfeld Strategic Advisors LLC | 227,330 | $13.7M | 0.07% | −97,392−30.0% | Reduced |
| D. E. Shaw & Co., Inc. | 223,922 | $13.5M | 0.01% | +204,982+1,082.3% | Added |
| Patient Square Capital LP | 220,000 | $13.3M | 2.06% | −7,000−3.1% | Reduced |
| New York State Common Retirement Fund | 210,471 | $12.7M | 0.02% | +21,966+11.7% | Added |
| Jennison Associates LLC | 208,060 | $12.6M | 0.01% | −1,110,754−84.2% | Reduced |
| Neuberger Berman Group LLC | 206,604 | $12.5M | 0.01% | +76,166+58.4% | Added |
| Trexquant Investment LP | 202,455 | $12.2M | 0.08% | +135,094+200.6% | Added |
| DnB Asset Management AS | 200,451 | $12.1M | 0.03% | +19,366+10.7% | Added |
| Integral Health Asset Management, LLC | 200,000 | $12.1M | 0.50% | 00.0% | Unchanged |
| Eversept Partners, LP | 196,532 | $11.9M | 0.65% | +66,958+51.7% | Added |
| Balyasny Asset Management LLC | 193,407 | $11.7M | 0.02% | −40,498−17.3% | Reduced |
| Deutsche Bank AG | 191,126 | $11.5M | 0.00% | +28,444+17.5% | Added |
| Renaissance Technologies LLC | 187,110 | $11.3M | 0.02% | −113,390−37.7% | Reduced |
| Silverarc Capital Management, LLC | 186,821 | $11.3M | 1.26% | −10,938−5.5% | Reduced |
| Boothbay Fund Management, LLC | 183,343 | $11.1M | 0.21% | −87,069−32.2% | Reduced |
| NEXTBio Capital Management LP | 183,225 | $11.1M | 5.09% | 00.0% | Unchanged |
| Wells Fargo & Company | 173,945 | $10.5M | 0.00% | +58,293+50.4% | Added |
| ADAR1 Capital Management, LLC | 166,550 | $10.1M | 0.47% | −62,349−27.2% | Reduced |
| Peregrine Capital Management LLC | 164,894 | $9.95M | 0.32% | +21,758+15.2% | Added |
| Swiss National Bank | 162,700 | $9.82M | 0.01% | +5,000+3.2% | Added |
| Foresite Capital Management IV, LLC | 160,000 | $9.66M | 3.33% | 00.0% | Unchanged |
| Woodline Partners LP | 155,302 | $9.37M | 0.03% | +5,000+3.3% | Added |
| Russell Investments Group, Ltd. | 153,227 | $9.25M | 0.01% | +23,828+18.4% | Added |
| HSBC Holdings PLC | 151,474 | $9.14M | 0.00% | +29,916+24.6% | Added |
| Susquehanna Portfolio Strategies, LLC | 133,059 | $8.03M | 0.13% | +114,591+620.5% | Added |
| Point72 Asset Management, L.P. | 130,378 | $7.87M | 0.01% | +130,378 | New |
| Granahan Investment Management Inc | 129,443 | $7.81M | 0.28% | +24,965+23.9% | Added |
| KBC Group NV | 129,010 | $7.79M | 0.02% | 00.0% | Unchanged |