Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2023
Institutional positions in Xenon Pharmaceuticals Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 204
- +26 vs. Q3 2023
- Shares held
- 72.1M
- +10.8M (+17.6%) vs. Q3 2023
- Total value
- $3.32B
- +$1.23B (+58.6%) vs. Q3 2023
- New holders
- 46
- 85 more added
- Sold out
- 20
- 52 more reduced
3 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 5,666,666 | $261.0M | 3.61% | +766,666+15.6% | Added |
| FMR LLC | 5,655,922 | $260.5M | 0.02% | +1,403,056+33.0% | Added |
| Driehaus Capital Management LLC | 4,345,180 | $200.1M | 2.41% | −167,825−3.7% | Reduced |
| Wellington Management Group LLP | 4,162,654 | $191.7M | 0.04% | +2,434,546+140.9% | Added |
| Polar Capital Holdings Plc | 3,066,628 | $141.2M | 0.98% | +62,881+2.1% | Added |
| Capital World Investors | 2,681,537 | $123.5M | 0.02% | +406,563+17.9% | Added |
| Capital International Investors | 2,455,683 | $113.1M | 0.03% | +8,863+0.4% | Added |
| Commodore Capital LP | 2,167,793 | $99.8M | 8.72% | +322,793+17.5% | Added |
| Paradigm Biocapital Advisors LP | 2,127,400 | $98.0M | 4.59% | +635,565+42.6% | Added |
| BlackRock Inc. | 2,067,063 | $95.2M | 0.00% | +1,075,606+108.5% | Added |
| Pictet Asset Management Holding SA | 2,040,400 | $94.0M | 0.10% | +101,621+5.2% | Added |
| Braidwell LP | 1,647,311 | $75.9M | 2.79% | −456,085−21.7% | Reduced |
| First Light Asset Management, LLC | 1,645,490 | $75.8M | 6.10% | +1,043,420+173.3% | Added |
| Alliancebernstein L.P. | 1,574,568 | $72.5M | 0.03% | +490,231+45.2% | Added |
| Marshall Wace, LLP | 1,528,648 | $70.4M | 0.13% | −625,746−29.0% | Reduced |
| Citadel Advisors LLC | 1,266,844 | $58.4M | 0.06% | +543,320+75.1% | Added |
| Rock Springs Capital Management LP | 1,255,577 | $57.8M | 1.43% | +77,575+6.6% | Added |
| Perceptive Advisors LLC | 1,100,748 | $50.7M | 1.13% | +483,248+78.3% | Added |
| Adage Capital Partners GP, L.L.C. | 1,048,725 | $48.3M | 0.10% | +498,725+90.7% | Added |
| Baker Bros. Advisors LP | 993,679 | $45.8M | 0.52% | +242,040+32.2% | Added |
| Janus Henderson Group PLC | 966,065 | $44.5M | 0.03% | +583,760+152.7% | Added |
| T. Rowe Price Investment Management, Inc. | 891,149 | $41.0M | 0.03% | +891,149 | New |
| BVF Inc | 890,072 | $41.0M | 1.03% | −937,886−51.3% | Reduced |
| Point72 Asset Management, L.P. | 875,065 | $40.3M | 0.12% | −250,643−22.3% | Reduced |
| Avidity Partners Management LP | 815,993 | $37.6M | 1.44% | +494,593+153.9% | Added |
| TimesSquare Capital Management, LLC | 793,954 | $36.6M | 0.54% | +203,379+34.4% | Added |
| Invesco Ltd. | 719,718 | $33.2M | 0.01% | +3,415+0.5% | Added |
| Lord, Abbett & Co. LLC | 717,972 | $33.1M | 0.12% | −431,196−37.5% | Reduced |
| Loomis Sayles & Co L P | 708,295 | $32.6M | 0.05% | −22,421−3.1% | Reduced |
| First Turn Management, LLC | 680,389 | $31.3M | 4.50% | +680,389 | New |
| Boxer Capital, LLC | 600,000 | $27.6M | 1.38% | 00.0% | Unchanged |
| Great Point Partners LLC | 600,000 | $27.6M | 4.71% | +99,999+20.0% | Added |
| Jennison Associates LLC | 566,396 | $26.1M | 0.02% | +352,573+164.9% | Added |
| Fiera Capital Corp | 553,030 | $25.5M | 0.08% | −7,516−1.3% | Reduced |
| OrbiMed Advisors LLC | 550,000 | $25.3M | 0.51% | −408,793−42.6% | Reduced |
| Candriam Luxembourg S.C.A. | 530,884 | $24.5M | 0.17% | −39,000−6.8% | Reduced |
| Affinity Asset Advisors, LLC | 460,000 | $21.2M | 4.22% | +159,562+53.1% | Added |
| Samlyn Capital, LLC | 421,155 | $19.4M | 0.42% | −530,600−55.7% | Reduced |
| Dimensional Fund Advisors LP | 402,668 | $18.5M | 0.01% | −24,457−5.7% | Reduced |
| Goldman Sachs Group Inc | 376,302 | $17.3M | 0.00% | +120,934+47.4% | Added |
| Federated Hermes, Inc. | 346,596 | $16.0M | 0.04% | +346,596 | New |
| Two Sigma Investments, LP | 340,015 | $15.7M | 0.04% | +259,382+321.7% | Added |
| Vanguard Group Inc | 323,495 | $14.9M | 0.00% | +56,669+21.2% | Added |
| Granahan Investment Management Inc | 302,581 | $13.9M | 0.46% | +66,291+28.1% | Added |
| Parkman Healthcare Partners LLC | 294,788 | $13.6M | 1.92% | +78,144+36.1% | Added |
| Franklin Resources Inc | 293,825 | $13.5M | 0.01% | +121,213+70.2% | Added |
| Altium Capital Management LP | 290,535 | $13.4M | 9.22% | +62,535+27.4% | Added |
| DAFNA Capital Management LLC | 276,739 | $12.7M | 3.05% | −3,799−1.4% | Reduced |
| Boone Capital Management LLC | 255,432 | $11.8M | 2.75% | +255,432 | New |
| Two Sigma Advisers, LP | 252,700 | $11.6M | 0.03% | +187,800+289.4% | Added |
| Ally Bridge Group (NY) LLC | 241,961 | $11.1M | 8.02% | −25,000−9.4% | Reduced |
| Westfield Capital Management Co LP | 237,495 | $10.9M | 0.06% | +237,495 | New |
| State Street Corp | 227,040 | $10.5M | 0.00% | +14,670+6.9% | Added |
| Tri Locum Partners LP | 225,564 | $10.4M | 5.10% | +53,809+31.3% | Added |
| Morgan Stanley | 225,147 | $10.4M | 0.00% | −17,998−7.4% | Reduced |
| Algert Global LLC | 217,320 | $10.0M | 0.40% | +88,833+69.1% | Added |
| Putnam Investments LLC | 215,545 | $9.93M | 0.01% | +43,609+25.4% | Added |
| Woodline Partners LP | 196,453 | $9.05M | 0.10% | +53,002+36.9% | Added |
| PFM Health Sciences, LP | 192,856 | $8.88M | 0.53% | +114,269+145.4% | Added |
| New York State Common Retirement Fund | 190,312 | $8.77M | 0.01% | +5,680+3.1% | Added |
| AXA S.A. | 187,821 | $8.65M | 0.03% | −4,542−2.4% | Reduced |
| Vestal Point Capital, LP | 175,000 | $8.06M | 0.85% | +175,000 | New |
| Russell Investments Group, Ltd. | 174,286 | $8.03M | 0.01% | +4,898+2.9% | Added |
| ExodusPoint Capital Management, LP | 165,267 | $7.61M | 0.09% | −194,571−54.1% | Reduced |
| Ensign Peak Advisors, Inc | 164,380 | $7.57M | 0.01% | 00.0% | Unchanged |
| Silverarc Capital Management, LLC | 163,168 | $7.52M | 2.32% | +109,172+202.2% | Added |
| Logos Global Management LP | 150,000 | $6.91M | 0.77% | −300,000−66.7% | Reduced |
| Bridger Management, LLC | 146,800 | $6.76M | 2.59% | +146,800 | New |
| Bank of America Corp | 133,412 | $6.14M | 0.00% | +9,445+7.6% | Added |
| DnB Asset Management AS | 126,375 | $5.82M | 0.03% | +4,605+3.8% | Added |
| Swiss National Bank | 123,800 | $5.70M | 0.00% | +12,100+10.8% | Added |
| Barclays PLC | 111,990 | $5.16M | 0.00% | +102,469+1,076.2% | Added |
| Nan Fung Group Holdings Ltd | 106,680 | $4.91M | 3.06% | 00.0% | Unchanged |
| Bamco Inc | 100,100 | $4.61M | 0.01% | 00.0% | Unchanged |
| Assenagon Asset Management S.A. | 99,731 | $4.59M | 0.01% | −47,962−32.5% | Reduced |
| State of Wisconsin Investment Board | 95,336 | $4.39M | 0.01% | −738−0.8% | Reduced |
| Atika Capital Management LLC | 93,234 | $4.29M | 0.61% | +93,234 | New |
| Schroder Investment Management Group | 91,500 | $4.21M | 0.01% | +91,500 | New |
| Nicholas Investment Partners, LP | 87,752 | $4.04M | 0.47% | −766,695−89.7% | Reduced |
| Schonfeld Strategic Advisors LLC | 87,500 | $4.03M | 0.03% | −111,484−56.0% | Reduced |
| D. E. Shaw & Co., Inc. | 84,153 | $3.88M | 0.01% | +43,606+107.5% | Added |
| HRT Financial LP | 83,069 | $3.83M | 0.03% | +47,859+135.9% | Added |
| Credit Suisse AG | 81,795 | $3.77M | 0.00% | +16,209+24.7% | Added |
| UBS Asset Management Americas Inc | 77,484 | $3.57M | 0.00% | +8,683+12.6% | Added |
| Millennium Management LLC | 76,965 | $3.55M | 0.00% | −18,528−19.4% | Reduced |
| Laurion Capital Management LP | 75,000 | $3.45M | 0.12% | +75,000 | New |
| State of New Jersey Common Pension Fund D | 71,013 | $3.27M | 0.01% | +6,559+10.2% | Added |
| Jefferies Financial Group Inc. | 66,723 | $3.07M | 0.05% | +55,635+501.8% | Added |
| Bank of New York Mellon Corp | 66,659 | $3.07M | 0.00% | −100,690−60.2% | Reduced |
| Moore Capital Management, LP | 65,000 | $2.99M | 0.07% | +65,000 | New |
| Voya Investment Management LLC | 64,940 | $2.99M | 0.00% | −2,200−3.3% | Reduced |
| Geode Capital Management, LLC | 62,073 | $2.86M | 0.00% | +6,128+11.0% | Added |
| Northern Trust Corp | 61,971 | $2.85M | 0.00% | −7,196−10.4% | Reduced |
| Prudential Financial Inc | 59,000 | $2.72M | 0.00% | +32,000+118.5% | Added |
| Wells Fargo & Company | 58,423 | $2.69M | 0.00% | −1,210−2.0% | Reduced |
| Soleus Capital Management, L.P. | 58,000 | $2.67M | 0.30% | +6,000+11.5% | Added |
| California State Teachers Retirement System | 55,987 | $2.58M | 0.00% | +11,037+24.6% | Added |
| Legal & General Group Plc | 53,649 | $2.47M | 0.00% | +8,936+20.0% | Added |
| Susquehanna International Group, LLP | 52,951 | $2.44M | 0.00% | +52,951 | New |
| JPMorgan Chase & Co | 52,788 | $2.43M | 0.00% | +2,491+5.0% | Added |