Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2022
Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 151
- +21 vs. Q1 2022
- Shares held
- 57.0M
- +7.91M (+16.1%) vs. Q1 2022
- Total value
- $1.73B
- +$235.7M (+15.7%) vs. Q1 2022
- New holders
- 38
- 55 more added
- Sold out
- 17
- 40 more reduced
2 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 4,900,000 | $149.1M | 2.95% | −85,000−1.7% | Reduced |
| FMR LLC | 4,572,368 | $139.1M | 0.01% | +738,892+19.3% | Added |
| Driehaus Capital Management LLC | 4,391,038 | $133.6M | 2.16% | +1,090,611+33.0% | Added |
| Polar Capital Holdings Plc | 2,540,059 | $77.3M | 0.60% | +350,000+16.0% | Added |
| Capital World Investors | 2,274,974 | $69.2M | 0.01% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 2,122,535 | $64.6M | 2.03% | −288,912−12.0% | Reduced |
| Marshall Wace, LLP | 1,990,372 | $60.5M | 0.14% | +456,314+29.7% | Added |
| Lord, Abbett & Co. LLC | 1,857,596 | $56.5M | 0.20% | +66,853+3.7% | Added |
| Holocene Advisors, LP | 1,829,152 | $55.6M | 0.34% | +919,524+101.1% | Added |
| Pictet Asset Management SA | 1,819,476 | $55.3M | 0.08% | +494,150+37.3% | Added |
| Citadel Advisors LLC | 1,648,039 | $50.1M | 0.07% | +206,959+14.4% | Added |
| Redmile Group, LLC | 1,639,344 | $49.9M | 1.90% | +1,639,344 | New |
| BVF Inc | 1,597,966 | $48.6M | 2.35% | 00.0% | Unchanged |
| Commodore Capital LP | 1,594,932 | $48.5M | 10.26% | +392,319+32.6% | Added |
| Capital International Investors | 1,582,508 | $48.1M | 0.01% | +714,211+82.3% | Added |
| OrbiMed Advisors LLC | 1,329,200 | $40.4M | 0.79% | +643,200+93.8% | Added |
| Rock Springs Capital Management LP | 1,123,604 | $34.2M | 0.99% | +281,106+33.4% | Added |
| Samlyn Capital, LLC | 1,116,436 | $34.0M | 0.68% | +485,707+77.0% | Added |
| Great Point Partners LLC | 1,104,334 | $33.6M | 8.66% | +184,334+20.0% | Added |
| Morgan Stanley | 998,072 | $30.4M | 0.00% | −442,099−30.7% | Reduced |
| Point72 Asset Management, L.P. | 901,506 | $27.4M | 0.13% | −1,244,944−58.0% | Reduced |
| BlackRock Inc. | 868,290 | $26.4M | 0.00% | +253,333+41.2% | Added |
| Candriam Luxembourg S.C.A. | 863,140 | $26.3M | 0.22% | +258,886+42.8% | Added |
| Baker Bros. Advisors LP | 751,639 | $22.9M | 0.13% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 630,000 | $19.2M | 0.04% | −20,000−3.1% | Reduced |
| Boxer Capital, LLC | 600,000 | $18.3M | 1.16% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 563,187 | $17.1M | 0.00% | −16,021−2.8% | Reduced |
| Millennium Management LLC | 492,691 | $15.0M | 0.02% | +356,365+261.4% | Added |
| Eventide Asset Management, LLC | 469,700 | $14.3M | 0.31% | +469,700 | New |
| Eversept Partners, LP | 465,911 | $14.2M | 1.38% | +55,890+13.6% | Added |
| Avidity Partners Management LP | 450,000 | $13.7M | 0.31% | +450,000 | New |
| DAFNA Capital Management LLC | 438,623 | $13.3M | 3.64% | +58,460+15.4% | Added |
| Alliancebernstein L.P. | 429,960 | $13.1M | 0.01% | +53,309+14.2% | Added |
| D. E. Shaw & Co., Inc. | 326,542 | $9.93M | 0.02% | −3,985−1.2% | Reduced |
| Goldman Sachs Group Inc | 296,314 | $9.01M | 0.00% | −428,023−59.1% | Reduced |
| Parkman Healthcare Partners LLC | 294,559 | $8.96M | 3.30% | −9,627−3.2% | Reduced |
| Granahan Investment Management Inc | 284,772 | $8.66M | 0.30% | +22,067+8.4% | Added |
| Janus Henderson Group PLC | 276,674 | $8.41M | 0.01% | +266,393+2,591.1% | Added |
| Acuta Capital Partners, LLC | 272,500 | $8.29M | 4.64% | +47,500+21.1% | Added |
| Ikarian Capital, LLC | 239,441 | $7.28M | 3.02% | 00.0% | Unchanged |
| Silverarc Capital Management, LLC | 232,630 | $7.08M | 3.32% | +131,549+130.1% | Added |
| Woodline Partners LP | 228,928 | $6.96M | 0.11% | +228,928 | New |
| State Street Corp | 197,221 | $6.00M | 0.00% | +25,234+14.7% | Added |
| AXA S.A. | 191,351 | $5.82M | 0.02% | −3,701−1.9% | Reduced |
| Vanguard Group Inc | 183,845 | $5.59M | 0.00% | +20,377+12.5% | Added |
| Kynam Capital Management, LP | 175,000 | $5.32M | 1.37% | −308,270−63.8% | Reduced |
| Dimensional Fund Advisors LP | 174,962 | $5.32M | 0.00% | −118,767−40.4% | Reduced |
| Moore Capital Management, LP | 172,071 | $5.23M | 0.16% | +143,392+500.0% | Added |
| Tri Locum Partners LP | 166,399 | $5.06M | 2.08% | +166,399 | New |
| Walleye Capital LLC | 161,927 | $4.93M | 0.14% | +7,619+4.9% | Added |
| EAM Global Investors LLC | 150,489 | $4.58M | 1.12% | +150,489 | New |
| Schonfeld Strategic Advisors LLC | 128,109 | $3.90M | 0.04% | +25,735+25.1% | Added |
| Polar Asset Management Partners Inc. | 124,000 | $3.77M | 0.05% | +45,700+58.4% | Added |
| Nan Fung Group Holdings Ltd | 114,380 | $3.48M | 2.39% | −83,500−42.2% | Reduced |
| Russell Investments Group, Ltd. | 107,899 | $3.28M | 0.01% | +33,980+46.0% | Added |
| Swiss National Bank | 107,800 | $3.28M | 0.00% | +10,300+10.6% | Added |
| LMR Partners LLP | 100,000 | $3.04M | 0.06% | +100,000 | New |
| Integral Health Asset Management, LLC | 97,281 | $2.96M | 0.61% | +97,281 | New |
| UBS Oconnor LLC | 96,208 | $2.93M | 0.03% | +96,208 | New |
| Allianz Asset Management GmbH | 88,630 | $2.70M | 0.00% | −13,555−13.3% | Reduced |
| Monashee Investment Management LLC | 85,000 | $2.59M | 0.94% | +85,000 | New |
| Bridger Management, LLC | 77,400 | $2.35M | 0.53% | +77,400 | New |
| Soleus Capital Management, L.P. | 75,000 | $2.28M | 0.37% | −114,797−60.5% | Reduced |
| Graham Capital Management, L.P. | 73,737 | $2.24M | 0.10% | +60,546+459.0% | Added |
| Knott David M Jr | 59,500 | $1.81M | 0.84% | −7,000−10.5% | Reduced |
| Ensign Peak Advisors, Inc | 56,291 | $1.71M | 0.00% | +47,771+560.7% | Added |
| Maven Securities LTD | 55,645 | $1.69M | 0.30% | +55,645 | New |
| Cubist Systematic Strategies, LLC | 52,678 | $1.60M | 0.01% | −21,361−28.9% | Reduced |
| Two Sigma Advisers, LP | 52,300 | $1.59M | 0.00% | −70,400−57.4% | Reduced |
| Ameriprise Financial Inc | 51,176 | $1.56M | 0.00% | −6,756−11.7% | Reduced |
| Northern Trust Corp | 47,996 | $1.46M | 0.00% | +3,220+7.2% | Added |
| CIBC World Markets Inc. | 46,887 | $1.43M | 0.01% | +5,550+13.4% | Added |
| State of Wisconsin Investment Board | 45,823 | $1.39M | 0.00% | +11,623+34.0% | Added |
| Geode Capital Management, LLC | 45,516 | $1.38M | 0.00% | +17,318+61.4% | Added |
| Nuveen Asset Management, LLC | 44,311 | $1.35M | 0.00% | −5,486−11.0% | Reduced |
| Altshuler Shaham Ltd | 42,000 | $1.28M | 0.02% | 00.0% | Unchanged |
| Cinctive Capital Management LP | 41,073 | $1.25M | 0.06% | −1,230−2.9% | Reduced |
| Pura Vida Investments, LLC | 40,002 | $1.22M | 0.19% | +25,000+166.6% | Added |
| California State Teachers Retirement System | 39,031 | $1.19M | 0.00% | +3,944+11.2% | Added |
| Scotia Capital Inc. | 37,474 | $1.14M | 0.01% | +3,258+9.5% | Added |
| Bank of America Corp | 36,655 | $1.11M | 0.00% | +30,376+483.8% | Added |
| Erste Asset Management GmbH | 35,000 | $1.08M | 0.02% | 00.0% | Unchanged |
| Advisory Research Inc | 35,000 | $1.06M | 0.10% | +35,000 | New |
| Susquehanna International Group, LLP | 34,389 | $1.05M | 0.00% | +14,198+70.3% | Added |
| Credit Suisse AG | 33,184 | $1.01M | 0.00% | +3,034+10.1% | Added |
| Alps Advisors Inc | 31,498 | $958.0K | 0.01% | +31,498 | New |
| ExodusPoint Capital Management, LP | 31,332 | $953.0K | 0.01% | +31,332 | New |
| VR Adviser, LLC | 30,000 | $913.0K | 0.18% | +30,000 | New |
| Tekla Capital Management LLC | 29,710 | $904.0K | 0.04% | +29,710 | New |
| Jefferies Group LLC | 27,828 | $846.5K | 0.02% | +27,828 | New |
| UBS Asset Management Americas Inc | 26,908 | $818.5K | 0.00% | −1,928−6.7% | Reduced |
| Algert Global LLC | 26,404 | $803.0K | 0.06% | +14,330+118.7% | Added |
| Boothbay Fund Management, LLC | 26,306 | $800.0K | 0.03% | +1,980+8.1% | Added |
| NJ State Employees Deferred Compensation Plan | 25,000 | $761.0K | 0.12% | 00.0% | Unchanged |
| Sanders Morris Harris LLC | 24,500 | $754.0K | 0.16% | +24,500 | New |
| Engineers Gate Manager LP | 22,747 | $692.0K | 0.03% | −10,058−30.7% | Reduced |
| SG Americas Securities, LLC | 22,453 | $683.0K | 0.01% | +22,453 | New |
| HighVista Strategies LLC | 22,435 | $682.0K | 0.41% | −5,557−19.9% | Reduced |
| Shell Asset Management Co | 22,025 | $670.0K | 0.02% | −60.0% | Reduced |
| Bamco Inc | 22,000 | $669.0K | 0.00% | −20,000−47.6% | Reduced |