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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2022

Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
151
+21 vs. Q1 2022
Shares held
57.0M
+7.91M (+16.1%) vs. Q1 2022
Total value
$1.73B
+$235.7M (+15.7%) vs. Q1 2022
New holders
38
55 more added
Sold out
17
40 more reduced

2 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 151 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ2 2022: $1.73B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2022.

Institutions holding XENE in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Chartwell Investment Partners, LLC21,508$654.0K0.03%+21,508New
Tudor Investment Corp Et Al20,336$619.0K0.02%+20,336New
Velan Capital Investment Management LP20,000$608.0K0.64%+20,000New
HRT Financial LP19,902$605.0K0.01%+19,902New
Natixis Advisors, L.P.19,379$590.0K0.00%+19,379New
Sio Capital Management, LLC16,368$498.0K0.20%−89,388−84.5%Reduced
New York State Common Retirement Fund16,000$487.0K0.00%+4,500+39.1%Added
Employees Retirement System of Texas16,001$487.0K0.01%+16,001New
Handelsbanken Fonder AB15,200$462.0K0.00%−2,400−13.6%Reduced
Elmwood Wealth Management, Inc.14,994$456.0K0.26%00.0%Unchanged
Guggenheim Capital LLC14,377$437.0K0.00%+184+1.3%Added
Victory Capital Management Inc13,138$400.0K0.00%−1,126−7.9%Reduced
DekaBank Deutsche Girozentrale12,400$378.0K0.00%00.0%Unchanged
Legal & General Group Plc11,273$343.0K0.00%+502+4.7%Added
Jupiter Asset Management Ltd11,138$338.0K0.00%−315−2.8%Reduced
Twinbeech Capital LP11,023$335.0K0.01%−16,445−59.9%Reduced
Supplemental Annuity Collective Trust of NJ11,000$335.0K0.13%00.0%Unchanged
Occudo Quantitative Strategies LP10,945$333.0K0.03%+10,945New
Public Employees Retirement Association of Colorado10,633$323.0K0.00%+10,633New
Arizona State Retirement System10,497$319.0K0.00%−659−5.9%Reduced
Stifel Financial Corp10,044$306.0K0.00%−823−7.6%Reduced
De Burlo Group Inc10,000$304.0K0.09%+10,000New
Laurion Capital Management LP10,000$304.0K0.01%+10,000New
Main Street Research LLC10,000$304.0K0.08%+10,000New
Birchview Capital, LP10,000$304.0K0.22%+10,000New
Pinz Capital Management, LP10,000$304.0K0.21%+10,000New
Sandia Investment Management LP9,900$301.0K0.04%+9,900New
Group One Trading, L.P.8,760$266.0K0.01%+4,153+90.1%Added
Y-Intercept (Hong Kong) Ltd7,324$223.0K0.03%+7,324New
Squarepoint Ops LLC7,050$214.0K0.00%+7,050New
Zurcher Kantonalbank (Zurich Cantonalbank)6,667$203.0K0.00%−66−1.0%Reduced
Advisors Asset Management, Inc.5,048$154.0K0.00%+5,048New
Amundi3,581$115.0K0.00%−745−17.2%Reduced
Virtus ETF Advisers LLC3,643$111.0K0.04%−2,435−40.1%Reduced
BNP Paribas Arbitrage, SA2,744$83.5K0.00%+1,410+105.7%Added
UBS Group AG2,472$76.0K0.00%+1,249+102.1%Added
JPMorgan Chase & Co2,446$74.0K0.00%−3,925−61.6%Reduced
Proequities, Inc.2,000$61.0K0.01%00.0%Unchanged
Citigroup Inc1,918$58.0K0.00%−100,557−98.1%Reduced
Great West Life Assurance Co1,857$56.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,462$44.0K0.00%00.0%Unchanged
High Net Worth Advisory Group LLC1,000$30.0K0.01%00.0%Unchanged
Simplex Trading, LLC940$28.0K0.00%+940New
International Biotechnology Trust PLC774$25.5K0.50%−24,726−97.0%Reduced
Macquarie Group Ltd671$20.0K0.00%00.0%Unchanged
Leonteq Securities AG530$16.1K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.263$8.00K0.00%+163+163.0%Added
IFP Advisors, Inc1,000$6.00K0.00%−1,000−50.0%Reduced
Daiwa Securities Group Inc.198$6.00K0.00%+57+40.4%Added
State of Wyoming64$2.00K0.00%+15+30.6%Added
Patriot Financial Group Insurance Agency, LLC35$1.00K0.00%00.0%Unchanged
Suvretta Capital Management, LLC0$00.00%−692,000−100.0%Sold out
Two Sigma Investments, LP0$00.00%−232,650−100.0%Sold out
Invesco Ltd.0$00.00%−198,701−100.0%Sold out
Renaissance Technologies LLC0$00.00%−150,777−100.0%Sold out
Ci Investments Inc.0$00.00%−100,705−100.0%Sold out
Ghost Tree Capital, LLC0$00.00%−100,000−100.0%Sold out
Affinity Asset Advisors, LLC0$00.00%−80,000−100.0%Sold out
Jump Financial, LLC0$00.00%−30,101−100.0%Sold out
Royal Bank of Canada0$00.00%−24,313−100.0%Sold out
Granite Point Capital Management, L.P.0$00.00%−20,000−100.0%Sold out
Jane Street Group, LLC0$00.00%−16,117−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−13,993−100.0%Sold out
Teacher Retirement System of Texas0$00.00%−8,545−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−7,658−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−400−100.0%Sold out
Brown Brothers Harriman & Co0$00.00%−294−100.0%Sold out
Barclays PLC0$00.00%−191−100.0%Sold out
Susquehanna Fundamental Investments, LLC––––Not filed
Parametric Portfolio Associates LLC––––Not filed