Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2024
Institutional positions in Xenon Pharmaceuticals Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 209
- +8 vs. Q3 2024
- Shares held
- 76.3M
- +1.44M (+1.9%) vs. Q3 2024
- Total value
- $2.99B
- +$42.4M (+1.4%) vs. Q3 2024
- New holders
- 29
- 66 more added
- Sold out
- 21
- 69 more reduced
2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 7,525,290 | $295.0M | 0.02% | +607,606+8.8% | Added |
| Avoro Capital Advisors LLC | 5,666,666 | $222.1M | 3.14% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 4,520,595 | $177.2M | 1.46% | −75,126−1.6% | Reduced |
| Wellington Management Group LLP | 3,777,611 | $148.1M | 0.03% | −65,836−1.7% | Reduced |
| Braidwell LP | 2,913,964 | $114.2M | 3.39% | +206,709+7.6% | Added |
| Janus Henderson Group PLC | 2,866,755 | $112.4M | 0.06% | +314,363+12.3% | Added |
| Commodore Capital LP | 2,740,000 | $107.4M | 7.87% | +40,000+1.5% | Added |
| Polar Capital Holdings Plc | 2,697,657 | $105.7M | 0.59% | +253,012+10.3% | Added |
| Capital International Investors | 2,547,210 | $99.9M | 0.02% | −33,962−1.3% | Reduced |
| Capital World Investors | 2,294,537 | $89.9M | 0.01% | −387,000−14.4% | Reduced |
| BlackRock, Inc. | 2,105,236 | $82.5M | 0.00% | −3260.0% | Reduced |
| Adage Capital Partners GP, L.L.C. | 1,863,473 | $73.0M | 0.13% | −220,499−10.6% | Reduced |
| Pictet Asset Management Holding SA | 1,496,511 | $58.7M | 0.06% | −32,303−2.1% | Reduced |
| Alliancebernstein L.P. | 1,443,180 | $56.6M | 0.02% | +18,445+1.3% | Added |
| T. Rowe Price Investment Management, Inc. | 1,437,831 | $56.4M | 0.03% | −65,977−4.4% | Reduced |
| JPMorgan Chase & Co | 1,356,895 | $53.2M | 0.00% | +380,112+38.9% | Added |
| Rock Springs Capital Management LP | 1,251,859 | $49.1M | 1.87% | −64,618−4.9% | Reduced |
| Affinity Asset Advisors, LLC | 1,161,237 | $45.5M | 7.11% | +17,216+1.5% | Added |
| First Light Asset Management, LLC | 1,160,580 | $45.5M | 4.35% | −21,082−1.8% | Reduced |
| Westfield Capital Management Co LP | 1,157,189 | $45.4M | 0.20% | +487,589+72.8% | Added |
| Samlyn Capital, LLC | 1,017,838 | $39.9M | 0.63% | −2,368−0.2% | Reduced |
| Baker Bros. Advisors LP | 993,679 | $39.0M | 0.42% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 947,877 | $37.2M | 0.77% | +36,457+4.0% | Added |
| Marshall Wace, LLP | 899,718 | $35.3M | 0.04% | −295,762−24.7% | Reduced |
| TimesSquare Capital Management, LLC | 848,850 | $33.3M | 0.48% | +70,557+9.1% | Added |
| Vestal Point Capital, LP | 810,000 | $31.8M | 1.88% | −15,000−1.8% | Reduced |
| Jennison Associates LLC | 801,553 | $31.4M | 0.02% | +224,892+39.0% | Added |
| Siren, L.L.C. | 743,769 | $29.2M | 1.29% | 00.0% | Unchanged |
| Loomis Sayles & Co L P | 687,145 | $26.9M | 0.03% | −20,077−2.8% | Reduced |
| First Turn Management, LLC | 684,986 | $26.9M | 4.81% | +359,768+110.6% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 663,704 | $26.0M | 0.06% | +224,630+51.2% | Added |
| Boxer Capital Management, LLC | 600,000 | $23.5M | 2.00% | +600,000 | New |
| Franklin Resources Inc | 575,590 | $22.6M | 0.01% | +9,675+1.7% | Added |
| Federated Hermes, Inc. | 558,500 | $21.9M | 0.05% | −177,700−24.1% | Reduced |
| Fiera Capital Corp | 535,887 | $21.0M | 0.07% | −18,313−3.3% | Reduced |
| Candriam Luxembourg S.C.A. | 492,181 | $19.3M | 0.11% | +28,320+6.1% | Added |
| Avidity Partners Management LP | 474,000 | $18.6M | 1.85% | −344,000−42.1% | Reduced |
| Goldman Sachs Group Inc | 410,246 | $16.1M | 0.00% | −49,379−10.7% | Reduced |
| StemPoint Capital LP | 375,845 | $14.7M | 3.70% | +375,845 | New |
| Millennium Management LLC | 346,040 | $13.6M | 0.01% | +137,014+65.5% | Added |
| Vanguard Group Inc | 342,779 | $13.4M | 0.00% | −1,586−0.5% | Reduced |
| Citadel Advisors LLC | 327,303 | $12.8M | 0.01% | −395,201−54.7% | Reduced |
| Perceptive Advisors LLC | 325,324 | $12.8M | 0.36% | −199,606−38.0% | Reduced |
| Saturn V Capital Management LLC | 322,470 | $12.6M | 4.95% | +322,470 | New |
| Two Sigma Advisers, LP | 298,700 | $11.7M | 0.03% | +25,000+9.1% | Added |
| Alyeska Investment Group, L.P. | 288,843 | $11.3M | 0.04% | 00.0% | Unchanged |
| State Street Corp | 288,722 | $11.3M | 0.00% | +9,209+3.3% | Added |
| Altium Capital Management LP | 288,000 | $11.3M | 3.52% | −72,600−20.1% | Reduced |
| Standard Life Aberdeen plc | 283,899 | $11.1M | 0.02% | +35,588+14.3% | Added |
| DAFNA Capital Management LLC | 273,739 | $10.7M | 2.73% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 273,352 | $10.7M | 0.02% | +29,773+12.2% | Added |
| Dimensional Fund Advisors LP | 259,970 | $10.2M | 0.00% | −39,895−13.3% | Reduced |
| Great Point Partners LLC | 245,272 | $9.61M | 4.53% | +245,272 | New |
| Algert Global LLC | 241,417 | $9.46M | 0.22% | +21,772+9.9% | Added |
| Assenagon Asset Management S.A. | 238,522 | $9.35M | 0.02% | +26,235+12.4% | Added |
| Walleye Capital LLC | 221,982 | $8.70M | 0.08% | +117,022+111.5% | Added |
| Russell Investments Group, Ltd. | 213,696 | $8.38M | 0.01% | −9,918−4.4% | Reduced |
| Invesco Ltd. | 209,554 | $8.21M | 0.00% | −6,268−2.9% | Reduced |
| DnB Asset Management AS | 203,243 | $7.97M | 0.03% | +12,620+6.6% | Added |
| MPM Oncology Impact Management LP | 197,212 | $7.73M | 1.10% | +31,412+18.9% | Added |
| Lord, Abbett & Co. LLC | 194,971 | $7.64M | 0.02% | +20,986+12.1% | Added |
| Parkman Healthcare Partners LLC | 193,004 | $7.57M | 1.01% | +1,346+0.7% | Added |
| UBS Asset Management Americas Inc | 191,852 | $7.52M | 0.00% | +29,169+17.9% | Added |
| AXA S.A. | 187,796 | $7.36M | 0.02% | −294−0.2% | Reduced |
| Balyasny Asset Management LLC | 184,580 | $7.24M | 0.02% | +100,382+119.2% | Added |
| Granahan Investment Management Inc | 182,333 | $7.15M | 0.30% | −18,544−9.2% | Reduced |
| Schroder Investment Management Group | 176,674 | $6.81M | 0.01% | 00.0% | Unchanged |
| Deep Track Capital, LP | 169,132 | $6.63M | 0.25% | +169,132 | New |
| Eversept Partners, LP | 155,540 | $6.10M | 0.63% | +155,540 | New |
| Bridger Management, LLC | 146,800 | $5.75M | 3.09% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 132,521 | $5.19M | 0.01% | 00.0% | Unchanged |
| Ally Bridge Group (NY) LLC | 129,291 | $5.07M | 4.35% | −82,500−39.0% | Reduced |
| Swiss National Bank | 126,600 | $4.96M | 0.00% | +1,300+1.0% | Added |
| PFM Health Sciences, LP | 116,998 | $4.59M | 0.35% | −62,880−35.0% | Reduced |
| Bank of America Corp | 106,906 | $4.19M | 0.00% | −20,550−16.1% | Reduced |
| Nan Fung Group Holdings Ltd | 106,680 | $4.18M | 3.58% | 00.0% | Unchanged |
| Bamco Inc | 100,100 | $3.92M | 0.01% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 96,584 | $3.79M | 0.01% | −4,398−4.4% | Reduced |
| Neuberger Berman Group LLC | 92,961 | $3.64M | 0.00% | +92,961 | New |
| Ameriprise Financial Inc | 92,350 | $3.62M | 0.00% | +25,967+39.1% | Added |
| D. E. Shaw & Co., Inc. | 86,973 | $3.41M | 0.00% | −117,919−57.6% | Reduced |
| Atika Capital Management LLC | 72,600 | $2.85M | 0.37% | −53,400−42.4% | Reduced |
| Geode Capital Management, LLC | 69,529 | $2.73M | 0.00% | +720+1.0% | Added |
| ExodusPoint Capital Management, LP | 68,884 | $2.70M | 0.03% | −193,747−73.8% | Reduced |
| Morgan Stanley | 68,062 | $2.67M | 0.00% | −171,880−71.6% | Reduced |
| HighVista Strategies LLC | 66,788 | $2.62M | 0.97% | −6,974−9.5% | Reduced |
| Northern Trust Corp | 65,783 | $2.58M | 0.00% | +22,377+51.6% | Added |
| Voya Investment Management LLC | 62,415 | $2.45M | 0.00% | +15,250+32.3% | Added |
| Ikarian Capital, LLC | 62,052 | $2.43M | 0.69% | −45,135−42.1% | Reduced |
| Alps Advisors Inc | 61,648 | $2.42M | 0.02% | +4,659+8.2% | Added |
| Legal & General Group Plc | 60,406 | $2.37M | 0.00% | +5,286+9.6% | Added |
| Royal Bank of Canada | 60,068 | $2.35M | 0.00% | +22,432+59.6% | Added |
| Wells Fargo & Company | 59,520 | $2.33M | 0.00% | −936−1.5% | Reduced |
| California State Teachers Retirement System | 55,492 | $2.18M | 0.00% | −512−0.9% | Reduced |
| Moore Capital Management, LP | 55,000 | $2.16M | 0.04% | 00.0% | Unchanged |
| State of New Jersey Common Pension Fund D | 54,033 | $2.12M | 0.01% | +5,460+11.2% | Added |
| BIT Capital GmbH | 53,928 | $2.11M | 0.19% | +53,928 | New |
| Deutsche Bank AG | 53,711 | $2.11M | 0.00% | 00.0% | Unchanged |
| Sphera Funds Management Ltd. | 52,097 | $2.04M | 0.38% | +52,097 | New |
| ADAR1 Capital Management, LLC | 50,547 | $1.98M | 0.41% | +22,644+81.2% | Added |