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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q4 2024

Institutional positions in Xenon Pharmaceuticals Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
209
+8 vs. Q3 2024
Shares held
76.3M
+1.44M (+1.9%) vs. Q3 2024
Total value
$2.99B
+$42.4M (+1.4%) vs. Q3 2024
New holders
29
66 more added
Sold out
21
69 more reduced

2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 209 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ4 2024: $2.99B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q3 2024.

Institutions holding XENE in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Hexagon Capital Partners LLC6$2350.00%+6New
C M Bidwell & Associates Ltd9$3530.00%00.0%Unchanged
J.Safra Asset Management Corp11$4240.00%00.0%Unchanged
Allworth Financial LP12$4710.00%00.0%Unchanged
Continuum Advisory, LLC27$1.06K0.00%00.0%Unchanged
Rhumbline Advisers29$1.14K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC30$1.18K0.00%−388−92.8%Reduced
CVA Family Office, LLC33$1.29K0.00%00.0%Unchanged
Whittier Trust Co of Nevada Inc37$1.45K0.00%+1+2.8%Added
GAMMA Investing LLC51$2.00K0.00%−8−13.6%Reduced
CWM, LLC58$2.00K0.00%+44+314.3%Added
Principal Securities, Inc.58$2.27K0.00%+13+28.9%Added
Quadrant Capital Group LLC66$2.59K0.00%+66New
Amundi89$3.52K0.00%+89New
Bell Investment Advisors, Inc99$3.88K0.00%+35+54.7%Added
Spire Wealth Management200$7.84K0.00%+200New
Clearstead Advisors, LLC218$8.55K0.00%00.0%Unchanged
Lindbrook Capital, LLC225$8.82K0.00%−4−1.7%Reduced
National Bank of Canada235$9.21K0.00%00.0%Unchanged
Ronald Blue Trust, Inc.248$9.72K0.00%−760−75.4%Reduced
Daiwa Securities Group Inc.252$10.0K0.00%−36−12.5%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.276$11.2K0.00%00.0%Unchanged
First Horizon Advisors, Inc.370$14.5K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.463$18.1K0.00%+4+0.9%Added
Parallel Advisors, LLC466$18.3K0.00%+85+22.3%Added
State of Wyoming544$21.3K0.00%00.0%Unchanged
Signaturefd, LLC571$22.4K0.00%+334+140.9%Added
US Bancorp586$23.0K0.00%−20−3.3%Reduced
Tower Research Capital LLC (TRC)647$25.4K0.00%−1,372−68.0%Reduced
GF Fund Management Co. Ltd.1,601$62.8K0.00%+1,601New
Virtus ETF Advisers LLC1,802$70.6K0.03%−623−25.7%Reduced
IFP Advisors, Inc1,958$76.9K0.00%−19−1.0%Reduced
Proequities, Inc.2,000$78.4K0.00%00.0%Unchanged
Quarry LP2,000$78.4K0.02%+2,000New
Mirae Asset Global Investments Co., Ltd.2,541$98.7K0.00%−199−7.3%Reduced
Nelson, Van Denburg & Campbell Wealth Management Group, LLC2,569$100.7K0.00%+2,569New
KBC Group NV2,742$107.0K0.00%+780+39.8%Added
BNP Paribas Arbitrage, SA3,332$130.6K0.00%−140−4.0%Reduced
Northwestern Mutual Wealth Management Co5,019$196.7K0.00%+19+0.4%Added
The PNC Financial Services Group, Inc.5,140$201.5K0.00%+180+3.6%Added
Magnetar Financial LLC5,363$210.2K0.00%+5,363New
Vident Advisory, LLC5,413$212.2K0.00%+5,413New
HighMark Wealth Management LLC6,100$239.1K0.14%+1,100+22.0%Added
NEOS Investment Management LLC6,111$239.6K0.01%+6,111New
Tema ETFs LLC6,111$239.6K0.10%+6,111New
Guggenheim Capital LLC6,177$242.1K0.00%−4,452−41.9%Reduced
Citigroup Inc6,448$252.8K0.00%+2,800+76.8%Added
Squarepoint Ops LLC6,554$256.9K0.00%−950−12.7%Reduced
UBS Group AG6,705$262.8K0.00%−6,585−49.5%Reduced
HRT Financial LP7,171$281.0K0.00%−22,470−75.8%Reduced
XTX Topco Ltd8,054$315.7K0.03%+8,054New
Bellevue Group AG8,200$321.4K0.01%00.0%Unchanged
Aquatic Capital Management LLC8,260$323.8K0.01%+8,260New
Verition Fund Management LLC8,297$325.2K0.00%+8,297New
Fox Run Management, L.L.C.8,621$337.9K0.06%−11,123−56.3%Reduced
Tudor Investment Corp Et Al8,671$339.9K0.00%−28,016−76.4%Reduced
Birchview Capital, LP10,000$392.0K0.32%00.0%Unchanged
Public Employees Retirement Association of Colorado10,633$417.0K0.00%00.0%Unchanged
Supplemental Annuity Collective Trust of NJ11,000$431.2K0.13%00.0%Unchanged
Elmwood Wealth Management, Inc.11,007$431.5K0.17%+3,400+44.7%Added
Jane Street Group, LLC11,138$436.6K0.00%+11,138New
Trexquant Investment LP11,397$446.8K0.01%−5,510−32.6%Reduced
Occudo Quantitative Strategies LP11,441$448.5K0.08%+630+5.8%Added
Allianz Asset Management GmbH12,400$486.1K0.00%+4,300+53.1%Added
KLP Kapitalforvaltning AS12,800$501.8K0.00%+12,800New
Advisors Asset Management, Inc.13,048$511.5K0.01%−544−4.0%Reduced
SG Americas Securities, LLC13,293$521.0K0.00%+5,577+72.3%Added
Brinker Capital Investments, LLC13,436$526.7K0.01%−1,067−7.4%Reduced
Orion Portfolio Solutions, LLC13,436$526.7K0.01%−1,067−7.4%Reduced
Renaissance Technologies LLC13,700$537.0K0.00%−30,300−68.9%Reduced
Nicholas Investment Partners, LP14,658$574.6K0.05%00.0%Unchanged
Schonfeld Strategic Advisors LLC15,150$593.9K0.00%+1,568+11.5%Added
Great West Life Assurance Co15,911$623.0K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.16,166$633.7K0.06%+1,594+10.9%Added
Boothbay Fund Management, LLC17,395$681.9K0.02%−12,750−42.3%Reduced
J. Safra Sarasin Holding AG17,786$697.2K0.01%+17,786New
Barclays PLC18,127$710.6K0.00%+3,134+20.9%Added
Prelude Capital Management, LLC18,266$716.0K0.06%00.0%Unchanged
Arizona State Retirement System18,666$731.7K0.00%+194+1.1%Added
Brevan Howard Capital Management LP19,005$745.0K0.02%+6,993+58.2%Added
Teacher Retirement System of Texas19,083$748.0K0.00%+2,994+18.6%Added
Zurcher Kantonalbank (Zurich Cantonalbank)19,274$755.5K0.00%+2,866+17.5%Added
CIBC World Markets Inc.19,835$778.0K0.00%00.0%Unchanged
Raymond James Financial Inc20,331$797.1K0.00%+20,331New
Nebula Research & Development LLC20,360$798.1K0.09%−3,905−16.1%Reduced
TD Asset Management Inc20,430$800.9K0.00%00.0%Unchanged
Stifel Financial Corp20,688$811.0K0.00%−883−4.1%Reduced
Knott David M Jr20,866$817.9K0.30%00.0%Unchanged
Sanders Morris Harris LLC21,500$842.8K0.13%00.0%Unchanged
Assetmark, Inc21,585$846.1K0.00%+1,915+9.7%Added
Handelsbanken Fonder AB22,700$890.0K0.00%00.0%Unchanged
Natixis Advisors, L.P.23,554$923.0K0.00%−3,604−13.3%Reduced
Rathbone Brothers plc23,666$927.7K0.00%00.0%Unchanged
NJ State Employees Deferred Compensation Plan25,000$980.0K0.12%00.0%Unchanged
Ensign Peak Advisors, Inc26,094$1.02M0.00%−136,970−84.0%Reduced
Allostery Investments LP30,000$1.18M2.31%+30,000New
Thrivent Financial for Lutherans30,699$1.20M0.00%−12,394−28.8%Reduced
TLS Advisors LLC32,956$1.29M2.95%00.0%Unchanged
Rhenman & Partners Asset Management AB35,000$1.37M0.14%00.0%Unchanged
DekaBank Deutsche Girozentrale39,000$1.50M0.00%00.0%Unchanged