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Allostery Investments LP

SEC CIK
0001978599
Latest filing
Nov 14, 2025

The latest 13F from Allostery Investments LP covers Q3 2025 (filed Nov 14, 2025) and reports no long positions. Livermore has 4 filings on Form 13F from this institution, going back to Q4 2024.

What changed in Q3 2025

Share counts compared with Q2 2025: how many positions were new, added to, reduced or sold out, and the biggest buys and sells. Dollar amounts are estimated at the quarter-end prices implied by the filing.

Full comparison
New
0
Added
0
Reduced
0
Sold out
20
Est. −$7.85M

Top 5 holdings

Share of this quarter's portfolio value

This filing reports no long positions.

Biggest buys

New and added positions, by estimated amount bought

None this quarter.

Largest weight increases

New and added positions, by percentage points of the portfolio gained

None this quarter.

Biggest sells

Reduced and sold-out positions, by estimated amount sold

  1. ABVXAbivax S.A.
    −$1.28MSold outHistory
  2. AKROAkero Therapeutics, Inc.
    −$1.20MSold outHistory
  3. AMLXAmylyx Pharmaceuticals, Inc.
    −$770.0KSold outHistory
  4. CNTACentessa Pharmaceuticals plc
    −$689.9KSold outHistory
  5. EOLSEvolus, Inc.
    −$552.6KSold outHistory

Largest weight decreases

Reduced and sold-out positions, by percentage points of the portfolio lost

  1. ABVXAbivax S.A.
    −16.31 pp16.3% → 0.0%History
  2. AKROAkero Therapeutics, Inc.
    −15.29 pp15.3% → 0.0%History
  3. AMLXAmylyx Pharmaceuticals, Inc.
    −9.81 pp9.8% → 0.0%History
  4. CNTACentessa Pharmaceuticals plc
    −8.79 pp8.8% → 0.0%History
  5. EOLSEvolus, Inc.
    −7.04 pp7.0% → 0.0%History

Metrics

13F metrics for Q3 2025, computed only from the numbers in the filings. Definitions below.

Portfolio value
$0
−$7.85M (−100.0%) vs. prior quarter
Positions
0
−20 vs. prior quarter
Top 10 concentration
–
Top 10 as share of value
Turnover
0.0%
Q3 2025, one quarter
Average holding period
–
Weighted by value

How these are calculated

  • Portfolio value: the market value of all long positions in the 13F, as reported at quarter end, excluding options.
  • Top 10 concentration: the combined value of the 10 largest positions as a share of portfolio value.
  • Turnover: the smaller of this quarter's estimated purchases and estimated sales, divided by the average of this and last quarter's portfolio value. Estimates multiply the change in shares by the quarter-end price implied by the filing (market value divided by shares); new positions use this quarter's value and sold-out positions last quarter's. Only positions reported in shares count, and it is not calculated when the previous quarter was not filed.
  • Average holding period: how many consecutive quarters each current position has been held (including this one; a quarter without the position or without a filing starts the count over), weighted by this quarter's value. Counting starts with the first 13F in Livermore (Q4 2024), so positions held before then are understated.

13F filings by quarter

4 quarters, going back to Q4 2024. Bars show each quarter's 13F portfolio value; quarters without a filing are left blank.

Peak $69.3M (Q1 2025)

Q4 2024: $50.9MQ1 2025: $69.3MQ2 2025: $7.85M
Q4 2024Q3 2025
13F filings of Allostery Investments LP by quarter
QuarterFiledPositionsValueTop 3 holdingsChangesFiling
Q3 2025Nov 14, 20250$0–vs. Q2 2025SEC
Q2 2025Aug 14, 202520$7.85MABVXAKROAMLXvs. Q1 2025SEC
Q1 2025May 15, 202541$69.3MABVXCNTAKALVvs. Q4 2024SEC
Q4 2024Feb 14, 202530$50.9MCNTAEOLSAPGE–SEC

13D and 13G filings

Companies where Allostery Investments LP reports owning 5% or more on Schedule 13D or 13G, and its latest filings.

Current stakes of 5% or more

Allostery Investments LP does not currently report owning 5% or more of any company.

Latest filings

4 filings on file made by Allostery Investments LP or listing it as a reporting person, newest first.

Schedule 13D and 13G filings by Allostery Investments LP
CompanyFiled (ET)FormStakeChangeEvent dateFiling
AVTXAvalo Therapeutics, Inc.Nov 14, 202413G/AOld format–––SEC
ORKAOruka Therapeutics, Inc.Nov 14, 202413G/AOld format–––SEC
AVTXAvalo Therapeutics, Inc.May 13, 202413GOld format–New–SEC
ORKAOruka Therapeutics, Inc.Apr 15, 202413GOld format–New–SEC