Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2022
Institutional positions in Xenon Pharmaceuticals Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 132
- +2 vs. Q4 2021
- Shares held
- 49.2M
- +1.48M (+3.1%) vs. Q4 2021
- Total value
- $1.50B
- +$10.8M (+0.7%) vs. Q4 2021
- New holders
- 18
- 49 more added
- Sold out
- 16
- 40 more reduced
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 4,985,000 | $152.4M | 2.78% | 00.0% | Unchanged |
| FMR LLC | 3,833,476 | $117.2M | 0.01% | −76,541−2.0% | Reduced |
| Driehaus Capital Management LLC | 3,300,427 | $100.9M | 1.24% | +177,198+5.7% | Added |
| Perceptive Advisors LLC | 2,411,447 | $73.7M | 1.53% | 00.0% | Unchanged |
| Capital World Investors | 2,274,974 | $69.5M | 0.01% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 2,190,059 | $67.0M | 0.39% | +502,015+29.7% | Added |
| Point72 Asset Management, L.P. | 2,146,450 | $65.6M | 0.29% | −846,147−28.3% | Reduced |
| Lord, Abbett & Co. LLC | 1,790,743 | $54.7M | 0.15% | −4,337−0.2% | Reduced |
| BVF Inc | 1,597,966 | $48.9M | 1.95% | −1,691,574−51.4% | Reduced |
| Marshall Wace, LLP | 1,534,058 | $46.9M | 0.10% | +313,101+25.6% | Added |
| Citadel Advisors LLC | 1,441,080 | $44.1M | 0.05% | +153,277+11.9% | Added |
| Morgan Stanley | 1,440,171 | $44.0M | 0.01% | +568,087+65.1% | Added |
| Pictet Asset Management SA | 1,325,326 | $40.5M | 0.05% | +1,325,326 | New |
| Commodore Capital LP | 1,202,613 | $36.8M | 8.21% | +112,487+10.3% | Added |
| Great Point Partners LLC | 920,000 | $28.1M | 6.81% | −30,000−3.2% | Reduced |
| Holocene Advisors, LP | 909,628 | $27.8M | 0.15% | +909,628 | New |
| Capital International Investors | 868,297 | $26.5M | 0.01% | −187,429−17.8% | Reduced |
| Rock Springs Capital Management LP | 842,498 | $25.8M | 0.65% | +71,131+9.2% | Added |
| Baker Bros. Advisors LP | 751,639 | $23.0M | 0.13% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 724,337 | $22.1M | 0.01% | +552,943+322.6% | Added |
| Suvretta Capital Management, LLC | 692,000 | $21.2M | 0.65% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 686,000 | $21.0M | 0.34% | +55,000+8.7% | Added |
| Adage Capital Partners GP, L.L.C. | 650,000 | $19.9M | 0.04% | −15,000−2.3% | Reduced |
| Samlyn Capital, LLC | 630,729 | $19.3M | 0.29% | +109,089+20.9% | Added |
| BlackRock Inc. | 614,957 | $18.8M | 0.00% | +47,385+8.3% | Added |
| Candriam Luxembourg S.C.A. | 604,254 | $18.5M | 0.13% | +73,743+13.9% | Added |
| Boxer Capital, LLC | 600,000 | $18.3M | 0.94% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 579,208 | $17.7M | 0.00% | −212,317−26.8% | Reduced |
| Kynam Capital Management, LP | 483,270 | $14.8M | 4.80% | −186,823−27.9% | Reduced |
| Eversept Partners, LP | 410,021 | $12.5M | 1.15% | +200,502+95.7% | Added |
| DAFNA Capital Management LLC | 380,163 | $11.6M | 3.03% | −22,504−5.6% | Reduced |
| Alliancebernstein L.P. | 376,651 | $11.5M | 0.00% | +82,553+28.1% | Added |
| D. E. Shaw & Co., Inc. | 330,527 | $10.1M | 0.01% | −144,613−30.4% | Reduced |
| Parkman Healthcare Partners LLC | 304,186 | $9.30M | 2.72% | −56,316−15.6% | Reduced |
| Dimensional Fund Advisors LP | 293,729 | $8.98M | 0.00% | +1,783+0.6% | Added |
| Granahan Investment Management Inc | 262,705 | $8.03M | 0.20% | +45,404+20.9% | Added |
| Ikarian Capital, LLC | 239,441 | $7.32M | 2.23% | +60,303+33.7% | Added |
| Two Sigma Investments, LP | 232,650 | $7.11M | 0.02% | −45,693−16.4% | Reduced |
| Acuta Capital Partners, LLC | 225,000 | $6.88M | 3.27% | 00.0% | Unchanged |
| Invesco Ltd. | 198,701 | $6.07M | 0.00% | −95,399−32.4% | Reduced |
| Nan Fung Group Holdings Ltd | 197,880 | $6.05M | 2.87% | 00.0% | Unchanged |
| AXA S.A. | 195,052 | $5.96M | 0.02% | +40.0% | Added |
| Soleus Capital Management, L.P. | 189,797 | $5.80M | 0.89% | −189,200−49.9% | Reduced |
| State Street Corp | 171,987 | $5.26M | 0.00% | +10,738+6.7% | Added |
| Vanguard Group Inc | 163,468 | $5.00M | 0.00% | +10,102+6.6% | Added |
| Walleye Capital LLC | 154,308 | $4.72M | 0.14% | +82,324+114.4% | Added |
| Renaissance Technologies LLC | 150,777 | $4.61M | 0.01% | −230,100−60.4% | Reduced |
| Millennium Management LLC | 136,326 | $4.17M | 0.01% | +45,705+50.4% | Added |
| Two Sigma Advisers, LP | 122,700 | $3.75M | 0.01% | −3,900−3.1% | Reduced |
| Sio Capital Management, LLC | 105,756 | $3.23M | 1.30% | +105,756 | New |
| Citigroup Inc | 102,475 | $3.13M | 0.00% | +100,174+4,353.5% | Added |
| Schonfeld Strategic Advisors LLC | 102,374 | $3.13M | 0.03% | +13,474+15.2% | Added |
| Allianz Asset Management GmbH | 102,185 | $3.12M | 0.00% | +32,280+46.2% | Added |
| Ci Investments Inc. | 100,705 | $3.08M | 0.01% | +100,705 | New |
| Ghost Tree Capital, LLC | 100,000 | $3.06M | 1.51% | 00.0% | Unchanged |
| Swiss National Bank | 97,500 | $2.98M | 0.00% | +10,100+11.6% | Added |
| Affinity Asset Advisors, LLC | 80,000 | $2.45M | 0.97% | −70,500−46.8% | Reduced |
| Polar Asset Management Partners Inc. | 78,300 | $2.39M | 0.03% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 74,039 | $2.26M | 0.02% | +59,498+409.2% | Added |
| Russell Investments Group, Ltd. | 73,919 | $2.26M | 0.00% | +21,748+41.7% | Added |
| Knott David M Jr | 66,500 | $2.03M | 0.70% | −19,988−23.1% | Reduced |
| Ameriprise Financial Inc | 57,932 | $1.77M | 0.00% | −389−0.7% | Reduced |
| Nuveen Asset Management, LLC | 49,797 | $1.57M | 0.00% | +7,913+18.9% | Added |
| Silverarc Capital Management, LLC | 101,081 | $1.43M | 0.78% | +1,081+1.1% | Added |
| Susquehanna Fundamental Investments, LLC | 45,647 | $1.40M | 0.03% | +24,781+118.8% | Added |
| Northern Trust Corp | 44,776 | $1.37M | 0.00% | −5,820−11.5% | Reduced |
| Cinctive Capital Management LP | 42,303 | $1.29M | 0.06% | 00.0% | Unchanged |
| Altshuler Shaham Ltd | 42,000 | $1.28M | 0.01% | −11,600−21.6% | Reduced |
| Bamco Inc | 42,000 | $1.28M | 0.00% | 00.0% | Unchanged |
| CIBC World Markets Inc. | 41,337 | $1.26M | 0.00% | −8,297−16.7% | Reduced |
| California State Teachers Retirement System | 35,087 | $1.07M | 0.00% | +1,579+4.7% | Added |
| Erste Asset Management GmbH | 35,000 | $1.05M | 0.02% | 00.0% | Unchanged |
| Scotia Capital Inc. | 34,216 | $1.05M | 0.01% | +520+1.5% | Added |
| State of Wisconsin Investment Board | 34,200 | $1.04M | 0.00% | +34,200 | New |
| Engineers Gate Manager LP | 32,805 | $1.00M | 0.04% | +23,722+261.2% | Added |
| Credit Suisse AG | 30,150 | $922.0K | 0.00% | +5,246+21.1% | Added |
| Jump Financial, LLC | 30,101 | $920.0K | 0.04% | −1,199−3.8% | Reduced |
| UBS Asset Management Americas Inc | 28,836 | $881.5K | 0.00% | +774+2.8% | Added |
| Moore Capital Management, LP | 28,679 | $877.0K | 0.03% | +28,679 | New |
| Geode Capital Management, LLC | 28,198 | $862.0K | 0.00% | 00.0% | Unchanged |
| HighVista Strategies LLC | 27,992 | $856.0K | 0.54% | −34,914−55.5% | Reduced |
| Twinbeech Capital LP | 27,468 | $840.0K | 0.04% | +20,590+299.4% | Added |
| Parametric Portfolio Associates LLC | 26,338 | $805.0K | 0.00% | +26,338 | New |
| NJ State Employees Deferred Compensation Plan | 25,000 | $764.0K | 0.10% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 24,326 | $744.0K | 0.02% | +5,950+32.4% | Added |
| Royal Bank of Canada | 24,313 | $743.0K | 0.00% | 00.0% | Unchanged |
| Shell Asset Management Co | 22,031 | $673.0K | 0.02% | −3,298−13.0% | Reduced |
| Susquehanna International Group, LLP | 20,191 | $617.0K | 0.00% | +20,191 | New |
| Granite Point Capital Management, L.P. | 20,000 | $611.0K | 0.31% | −5,000−20.0% | Reduced |
| Handelsbanken Fonder AB | 17,600 | $538.0K | 0.00% | −3,100−15.0% | Reduced |
| Jane Street Group, LLC | 16,117 | $493.0K | 0.00% | +16,117 | New |
| Pura Vida Investments, LLC | 15,002 | $459.0K | 0.06% | −33,500−69.1% | Reduced |
| Elmwood Wealth Management, Inc. | 14,994 | $458.0K | 0.24% | −3,086−17.1% | Reduced |
| Guggenheim Capital LLC | 14,193 | $434.0K | 0.00% | +509+3.7% | Added |
| Dynamic Technology Lab Private Ltd | 13,993 | $428.0K | 0.05% | +13,993 | New |
| Victory Capital Management Inc | 14,264 | $403.0K | 0.00% | +6,719+89.1% | Added |
| Graham Capital Management, L.P. | 13,191 | $403.0K | 0.02% | +13,191 | New |
| DekaBank Deutsche Girozentrale | 12,400 | $373.0K | 0.00% | +1,100+9.7% | Added |
| Algert Global LLC | 12,074 | $369.0K | 0.02% | +12,074 | New |
| New York State Common Retirement Fund | 11,500 | $352.0K | 0.00% | +3,400+42.0% | Added |