Skip to main content

Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2023

Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
175
+13 vs. Q1 2023
Shares held
61.3M
+174.4K (+0.3%) vs. Q1 2023
Total value
$2.36B
+$174.7M (+8.0%) vs. Q1 2023
New holders
33
57 more added
Sold out
20
56 more reduced

1 institution that held it in Q1 2023 haven't filed for Q2 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 175 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ2 2023: $2.36B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2023.

Institutions holding XENE in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC5,188,707$199.8M0.02%+460,858+9.7%Added
Avoro Capital Advisors LLC4,900,000$188.7M2.56%00.0%Unchanged
Driehaus Capital Management LLC4,760,853$183.3M2.31%+105,928+2.3%Added
Polar Capital Holdings Plc3,022,071$116.3M0.80%+5,253+0.2%Added
Capital International Investors2,321,991$89.4M0.02%00.0%Unchanged
Marshall Wace, LLP2,320,419$89.3M0.19%−1670.0%Reduced
Capital World Investors2,274,974$87.6M0.02%00.0%Unchanged
Pictet Asset Management SA2,032,730$78.3M0.09%+28,433+1.4%Added
Lord, Abbett & Co. LLC1,958,540$75.4M0.26%+175,929+9.9%Added
Commodore Capital LP1,845,000$71.0M7.98%00.0%Unchanged
Braidwell LP1,828,353$70.4M2.30%−308,757−14.4%Reduced
BVF Inc1,827,958$70.4M1.96%00.0%Unchanged
Perceptive Advisors LLC1,223,377$47.1M1.37%−608,797−33.2%Reduced
Rock Springs Capital Management LP1,178,002$45.4M1.08%00.0%Unchanged
Redmile Group, LLC1,120,476$43.1M1.66%−205,356−15.5%Reduced
OrbiMed Advisors LLC1,096,000$42.2M0.82%−53,100−4.6%Reduced
Wellington Management Group LLP1,051,051$40.5M0.01%+803,614+324.8%Added
BlackRock Inc.994,040$38.3M0.00%+94,886+10.6%Added
Paradigm Biocapital Advisors LP989,327$38.1M3.08%+338,259+52.0%Added
Samlyn Capital, LLC939,909$36.2M0.63%−219,085−18.9%Reduced
Nicholas Investment Partners, LP791,118$30.5M2.08%+354,403+81.2%Added
Loomis Sayles & Co L P753,526$29.0M0.05%−7,041−0.9%Reduced
Baker Bros. Advisors LP751,639$28.9M0.17%00.0%Unchanged
Holocene Advisors, LP712,478$27.4M0.12%−273,717−27.8%Reduced
Candriam Luxembourg S.C.A.705,884$27.2M0.20%−13,322−1.9%Reduced
Invesco Ltd.699,985$26.9M0.01%+683,514+4,149.8%Added
Adage Capital Partners GP, L.L.C.670,000$25.8M0.06%−80,000−10.7%Reduced
Boxer Capital, LLC600,000$23.1M1.07%00.0%Unchanged
Fiera Capital Corp549,341$21.1M0.06%+549,341New
Great Point Partners LLC530,000$20.4M4.09%−288,505−35.2%Reduced
Citadel Advisors LLC501,012$19.3M0.02%−370,222−42.5%Reduced
Avidity Partners Management LP481,300$18.5M0.65%+481,300New
TimesSquare Capital Management, LLC426,925$16.4M0.24%+19,130+4.7%Added
Eventide Asset Management, LLC413,906$15.9M0.27%−227,294−35.4%Reduced
First Light Asset Management, LLC338,646$13.0M1.02%+59,202+21.2%Added
Janus Henderson Group PLC327,344$12.6M0.01%+5,879+1.8%Added
Woodline Partners LP290,400$11.2M0.13%−129,629−30.9%Reduced
DAFNA Capital Management LLC280,538$10.8M2.95%−35,554−11.2%Reduced
Goldman Sachs Group Inc275,080$10.6M0.00%−10,343−3.6%Reduced
Logos Global Management LP275,000$10.6M1.46%−625,000−69.4%Reduced
Ally Bridge Group (NY) LLC266,961$10.3M12.45%00.0%Unchanged
Dimensional Fund Advisors LP262,107$10.1M0.00%+196,841+301.6%Added
Vanguard Group Inc261,353$10.1M0.00%+11,999+4.8%Added
Granahan Investment Management Inc236,753$9.11M0.28%−39,259−14.2%Reduced
Altium Capital Management LP228,000$8.78M6.86%+228,000New
Parkman Healthcare Partners LLC217,740$8.38M1.45%−59,543−21.5%Reduced
Millennium Management LLC213,338$8.21M0.01%−8,132−3.7%Reduced
State Street Corp212,550$8.18M0.00%+5,094+2.5%Added
State of Wisconsin Investment Board212,129$8.17M0.02%−1,927−0.9%Reduced
Bank of New York Mellon Corp211,741$8.15M0.00%+12,354+6.2%Added
Morgan Stanley205,536$7.91M0.00%−37,445−15.4%Reduced
Bank of Montreal191,011$7.83M0.00%+191,011New
AXA S.A.193,035$7.43M0.02%+2,655+1.4%Added
Jennison Associates LLC188,391$7.25M0.01%+188,391New
Ghost Tree Capital, LLC185,000$7.12M2.57%−15,000−7.5%Reduced
New York State Common Retirement Fund184,631$7.11M0.01%+164,952+838.2%Added
Schonfeld Strategic Advisors LLC180,143$6.94M0.06%−119,976−40.0%Reduced
Franklin Resources Inc172,612$6.65M0.00%+30.0%Added
Eversept Partners, LP171,378$6.60M0.70%−31,894−15.7%Reduced
Putnam Investments LLC165,262$6.36M0.01%+11,807+7.7%Added
Ensign Peak Advisors, Inc164,380$6.33M0.01%00.0%Unchanged
Bank of America Corp159,376$6.14M0.00%+25,265+18.8%Added
Russell Investments Group, Ltd.150,456$5.79M0.01%+65,098+76.3%Added
Point72 Asset Management, L.P.148,208$5.71M0.02%−356,416−70.6%Reduced
Algert Global LLC144,877$5.58M0.24%+106,470+277.2%Added
Ikarian Capital, LLC135,486$5.22M1.84%−25,000−15.6%Reduced
Nan Fung Group Holdings Ltd114,380$4.40M2.81%00.0%Unchanged
DnB Asset Management AS112,629$4.34M0.02%+13,770+13.9%Added
Swiss National Bank109,800$4.23M0.00%+8,500+8.4%Added
PFM Health Sciences, LP100,147$3.86M0.16%00.0%Unchanged
Bamco Inc100,100$3.85M0.01%+27,100+37.1%Added
Silverarc Capital Management, LLC99,756$3.84M1.30%+3,113+3.2%Added
D. E. Shaw & Co., Inc.98,745$3.80M0.01%−107,927−52.2%Reduced
Castleark Management LLC94,490$3.64M0.16%+16,750+21.5%Added
Walleye Capital LLC89,704$3.45M0.06%−15,628−14.8%Reduced
JPMorgan Chase & Co79,217$3.05M0.00%+46,430+141.6%Added
Moran Wealth Management, LLC68,930$2.65M0.10%+1,317+1.9%Added
Atika Capital Management LLC68,050$2.62M0.33%+600+0.9%Added
Tekla Capital Management LLC67,506$2.60M0.10%−16,208−19.4%Reduced
Voya Investment Management LLC67,140$2.58M0.00%00.0%Unchanged
Alliancebernstein L.P.66,016$2.54M0.00%−41,946−38.9%Reduced
Soleus Capital Management, L.P.66,000$2.54M0.28%+66,000New
Credit Suisse AG65,827$2.53M0.00%+7,757+13.4%Added
Northern Trust Corp65,483$2.52M0.00%+4,480+7.3%Added
State of New Jersey Common Pension Fund D64,454$2.48M0.01%00.0%Unchanged
Affinity Asset Advisors, LLC60,376$2.32M0.91%−29,624−32.9%Reduced
Wells Fargo & Company58,593$2.26M0.00%+54,647+1,384.9%Added
Geode Capital Management, LLC55,915$2.15M0.00%+190+0.3%Added
UBS Asset Management Americas Inc53,052$1.90M0.00%00.0%Unchanged
J. Goldman & Co LP48,041$1.85M0.11%+48,041New
Alps Advisors Inc46,723$1.80M0.02%+5,195+12.5%Added
Advisory Research Inc44,422$1.71M0.22%+17,582+65.5%Added
California State Teachers Retirement System44,375$1.71M0.00%+3,167+7.7%Added
Legal & General Group Plc42,792$1.65M0.00%−4,683−9.9%Reduced
CIBC World Markets Inc.41,222$1.59M0.01%+8,473+25.9%Added
Nuveen Asset Management, LLC40,199$1.55M0.00%−13,108−24.6%Reduced
SG Americas Securities, LLC39,262$1.51M0.01%+13,385+51.7%Added
UBS Oconnor LLC38,676$1.49M0.03%−24,715−39.0%Reduced
Erste Asset Management GmbH35,000$1.35M0.02%00.0%Unchanged
TLS Advisors LLC33,756$1.30M5.58%00.0%Unchanged