Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2023
Institutional positions in Xenon Pharmaceuticals Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 163
- +4 vs. Q4 2022
- Shares held
- 61.1M
- +745.1K (+1.2%) vs. Q4 2022
- Total value
- $2.19B
- −$195.6M (−8.2%) vs. Q4 2022
- New holders
- 29
- 52 more added
- Sold out
- 25
- 46 more reduced
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 4,900,000 | $175.4M | 2.60% | 00.0% | Unchanged |
| FMR LLC | 4,727,849 | $169.2M | 0.02% | +37,020+0.8% | Added |
| Driehaus Capital Management LLC | 4,654,925 | $166.6M | 2.34% | −26,872−0.6% | Reduced |
| Polar Capital Holdings Plc | 3,016,818 | $108.0M | 0.79% | −29,056−1.0% | Reduced |
| Capital International Investors | 2,321,991 | $83.1M | 0.02% | +222,412+10.6% | Added |
| Marshall Wace, LLP | 2,320,586 | $83.1M | 0.20% | −45,592−1.9% | Reduced |
| Capital World Investors | 2,274,974 | $81.4M | 0.02% | 00.0% | Unchanged |
| Braidwell LP | 2,137,110 | $76.5M | 2.52% | +589,000+38.0% | Added |
| Pictet Asset Management SA | 2,004,297 | $71.7M | 0.09% | −115,322−5.4% | Reduced |
| Commodore Capital LP | 1,845,000 | $66.0M | 10.05% | +185,889+11.2% | Added |
| Perceptive Advisors LLC | 1,832,174 | $65.6M | 1.94% | −89,099−4.6% | Reduced |
| BVF Inc | 1,827,958 | $65.4M | 2.39% | +556,715+43.8% | Added |
| Lord, Abbett & Co. LLC | 1,782,611 | $63.8M | 0.23% | −341,398−16.1% | Reduced |
| Redmile Group, LLC | 1,325,832 | $47.5M | 2.06% | −1,034,582−43.8% | Reduced |
| Rock Springs Capital Management LP | 1,178,002 | $42.2M | 1.01% | +2,330+0.2% | Added |
| Samlyn Capital, LLC | 1,158,994 | $41.5M | 0.76% | −34,820−2.9% | Reduced |
| OrbiMed Advisors LLC | 1,149,100 | $41.1M | 0.81% | 00.0% | Unchanged |
| Holocene Advisors, LP | 986,195 | $35.3M | 0.18% | −205,443−17.2% | Reduced |
| Logos Global Management LP | 900,000 | $32.2M | 4.61% | 00.0% | Unchanged |
| BlackRock Inc. | 899,154 | $32.2M | 0.00% | −26,469−2.9% | Reduced |
| Citadel Advisors LLC | 871,234 | $31.2M | 0.03% | −293,173−25.2% | Reduced |
| Great Point Partners LLC | 818,505 | $29.3M | 5.79% | −31,495−3.7% | Reduced |
| Loomis Sayles & Co L P | 760,567 | $27.2M | 0.05% | +83,402+12.3% | Added |
| Baker Bros. Advisors LP | 751,639 | $26.9M | 0.15% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 750,000 | $26.8M | 0.06% | +25,000+3.4% | Added |
| Candriam Luxembourg S.C.A. | 719,206 | $23.7M | 0.16% | −16,678−2.3% | Reduced |
| Paradigm Biocapital Advisors LP | 651,068 | $23.3M | 2.21% | +651,068 | New |
| Eventide Asset Management, LLC | 641,200 | $22.9M | 0.42% | 00.0% | Unchanged |
| Boxer Capital, LLC | 600,000 | $21.5M | 1.05% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 504,624 | $18.1M | 0.06% | −673,700−57.2% | Reduced |
| Nicholas Investment Partners, LP | 436,715 | $15.6M | 1.19% | +184,413+73.1% | Added |
| Woodline Partners LP | 420,029 | $15.0M | 0.21% | +121,589+40.7% | Added |
| TimesSquare Capital Management, LLC | 407,795 | $14.6M | 0.21% | −74,385−15.4% | Reduced |
| Norges Bank | 365,830 | $13.1M | 0.00% | +365,830 | New |
| Janus Henderson Group PLC | 321,465 | $11.5M | 0.01% | +29,679+10.2% | Added |
| DAFNA Capital Management LLC | 316,092 | $11.3M | 3.39% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 302,980 | $10.8M | 0.12% | +302,980 | New |
| Schonfeld Strategic Advisors LLC | 300,119 | $10.7M | 0.10% | +131,706+78.2% | Added |
| Goldman Sachs Group Inc | 285,423 | $10.2M | 0.00% | +1,882+0.7% | Added |
| First Light Asset Management, LLC | 279,444 | $10.0M | 0.90% | +279,444 | New |
| Parkman Healthcare Partners LLC | 277,283 | $9.92M | 2.16% | +41,792+17.7% | Added |
| Granahan Investment Management Inc | 276,012 | $9.88M | 0.30% | −48,238−14.9% | Reduced |
| Ally Bridge Group (NY) LLC | 266,961 | $9.55M | 12.52% | +266,961 | New |
| Vanguard Group Inc | 249,354 | $8.92M | 0.00% | +57,278+29.8% | Added |
| Wellington Management Group LLP | 247,437 | $8.86M | 0.00% | +247,437 | New |
| Morgan Stanley | 242,981 | $8.70M | 0.00% | +154,847+175.7% | Added |
| Tri Locum Partners LP | 221,730 | $7.94M | 2.42% | +128,366+137.5% | Added |
| Millennium Management LLC | 221,470 | $7.93M | 0.01% | −373,071−62.7% | Reduced |
| Nomura Holdings Inc | 221,095 | $7.91M | 0.08% | +221,095 | New |
| State of Wisconsin Investment Board | 214,056 | $7.66M | 0.02% | −3,564−1.6% | Reduced |
| State Street Corp | 207,456 | $7.42M | 0.00% | +10,020+5.1% | Added |
| D. E. Shaw & Co., Inc. | 206,672 | $7.40M | 0.01% | −153,749−42.7% | Reduced |
| Eversept Partners, LP | 203,272 | $7.28M | 0.65% | −72,432−26.3% | Reduced |
| Ghost Tree Capital, LLC | 200,000 | $7.16M | 2.71% | +200,000 | New |
| Bank of New York Mellon Corp | 199,387 | $7.14M | 0.00% | −188,973−48.7% | Reduced |
| AXA S.A. | 190,380 | $6.81M | 0.02% | −414−0.2% | Reduced |
| Franklin Resources Inc | 172,609 | $6.18M | 0.00% | +172,609 | New |
| Ensign Peak Advisors, Inc | 164,380 | $5.88M | 0.01% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 160,486 | $5.74M | 2.38% | 00.0% | Unchanged |
| Putnam Investments LLC | 153,455 | $5.49M | 0.01% | +795+0.5% | Added |
| Bank of America Corp | 134,111 | $4.80M | 0.00% | +45,363+51.1% | Added |
| Nan Fung Group Holdings Ltd | 114,380 | $4.09M | 2.79% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 107,962 | $3.86M | 0.00% | +51,127+90.0% | Added |
| Walleye Capital LLC | 105,332 | $3.77M | 0.08% | +18,815+21.7% | Added |
| Swiss National Bank | 101,300 | $3.63M | 0.00% | −11,400−10.1% | Reduced |
| PFM Health Sciences, LP | 100,147 | $3.58M | 0.17% | +82,659+472.7% | Added |
| DnB Asset Management AS | 98,859 | $3.54M | 0.02% | +4,308+4.6% | Added |
| Silverarc Capital Management, LLC | 96,643 | $3.46M | 1.55% | −157,012−61.9% | Reduced |
| Affinity Asset Advisors, LLC | 90,000 | $3.22M | 1.24% | +40,000+80.0% | Added |
| Russell Investments Group, Ltd. | 85,358 | $3.05M | 0.01% | +1,028+1.2% | Added |
| Tekla Capital Management LLC | 83,714 | $3.00M | 0.11% | 00.0% | Unchanged |
| Castleark Management LLC | 77,740 | $2.78M | 0.14% | 00.0% | Unchanged |
| Bamco Inc | 73,000 | $2.61M | 0.01% | +25,600+54.0% | Added |
| Moran Wealth Management, LLC | 67,613 | $2.42M | 0.09% | +67,613 | New |
| Atika Capital Management LLC | 67,450 | $2.41M | 0.38% | +67,450 | New |
| Voya Investment Management LLC | 67,140 | $2.40M | 0.00% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 65,266 | $2.34M | 0.00% | −249,407−79.3% | Reduced |
| State of New Jersey Common Pension Fund D | 64,454 | $2.31M | 0.01% | 00.0% | Unchanged |
| UBS Oconnor LLC | 63,391 | $2.27M | 0.05% | +63,391 | New |
| Northern Trust Corp | 61,003 | $2.18M | 0.00% | +786+1.3% | Added |
| Credit Suisse AG | 58,070 | $2.08M | 0.00% | +3,281+6.0% | Added |
| Geode Capital Management, LLC | 55,725 | $1.99M | 0.00% | +440+0.8% | Added |
| Weiss Multi-Strategy Advisers LLC | 54,140 | $1.94M | 0.05% | +54,140 | New |
| Nuveen Asset Management, LLC | 53,307 | $1.91M | 0.00% | +2,027+4.0% | Added |
| UBS Asset Management Americas Inc | 53,052 | $1.90M | 0.00% | +14,114+36.2% | Added |
| Legal & General Group Plc | 47,475 | $1.70M | 0.00% | +31,947+205.7% | Added |
| Alps Advisors Inc | 41,528 | $1.49M | 0.01% | −843−2.0% | Reduced |
| California State Teachers Retirement System | 41,208 | $1.47M | 0.00% | +573+1.4% | Added |
| Knott David M Jr | 40,000 | $1.43M | 0.60% | −19,500−32.8% | Reduced |
| Algert Global LLC | 38,407 | $1.37M | 0.06% | +1,991+5.5% | Added |
| Erste Asset Management GmbH | 35,000 | $1.25M | 0.02% | 00.0% | Unchanged |
| Moore Capital Management, LP | 34,417 | $1.23M | 0.04% | −95,000−73.4% | Reduced |
| TLS Advisors LLC | 33,756 | $1.21M | 6.21% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 32,787 | $1.17M | 0.00% | +30,700+1,471.0% | Added |
| CIBC World Markets Inc. | 32,749 | $1.17M | 0.00% | +10,199+45.2% | Added |
| Tudor Investment Corp Et Al | 29,908 | $1.07M | 0.02% | +29,908 | New |
| Kynam Capital Management, LP | 28,696 | $1.03M | 0.13% | −191−0.7% | Reduced |
| Victory Capital Management Inc | 28,190 | $1.01M | 0.00% | +28,190 | New |
| Advisory Research Inc | 26,840 | $960.6K | 0.16% | −5,891−18.0% | Reduced |
| SG Americas Securities, LLC | 25,877 | $926.0K | 0.01% | −9,588−27.0% | Reduced |