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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 2 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2023

Institutional positions in Xenon Pharmaceuticals Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
163
+4 vs. Q4 2022
Shares held
61.1M
+745.1K (+1.2%) vs. Q4 2022
Total value
$2.19B
−$195.6M (−8.2%) vs. Q4 2022
New holders
29
52 more added
Sold out
25
46 more reduced

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 163 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ1 2023: $2.19B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q4 2022.

Institutions holding XENE in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
International Biotechnology Trust PLC25,500$912.4K0.25%00.0%Unchanged
HighVista Strategies LLC25,340$906.9K0.74%00.0%Unchanged
NJ State Employees Deferred Compensation Plan25,000$894.8K0.14%00.0%Unchanged
Chartwell Investment Partners, LLC22,168$793.0K0.03%−1,462−6.2%Reduced
Prelude Capital Management, LLC22,012$787.8K0.05%+9,243+72.4%Added
Natixis Advisors, L.P.21,741$778.0K0.00%+249+1.2%Added
Allianz Asset Management GmbH20,000$715.8K0.00%00.0%Unchanged
DekaBank Deutsche Girozentrale20,000$708.0K0.00%00.0%Unchanged
New York State Common Retirement Fund19,679$704.3K0.00%+3,029+18.2%Added
Guggenheim Capital LLC19,222$688.0K0.01%+129+0.7%Added
Gsa Capital Partners LLP18,562$664.0K0.07%+4,799+34.9%Added
Invesco Ltd.16,471$589.5K0.00%+16,471New
Susquehanna International Group, LLP15,569$557.2K0.00%+15,569New
Elmwood Wealth Management, Inc.14,994$536.6K0.25%00.0%Unchanged
Shell Asset Management Co14,598$522.0K0.02%−51−0.3%Reduced
Qube Research & Technologies Ltd14,453$517.3K0.00%−61,306−80.9%Reduced
Teacher Retirement System of Texas14,451$517.0K0.00%+332+2.4%Added
Handelsbanken Fonder AB14,100$505.0K0.00%00.0%Unchanged
Arizona State Retirement System13,591$486.4K0.00%+414+3.1%Added
Oppenheimer & Co Inc12,615$451.5K0.01%+12,615New
Royal Bank of Canada12,484$447.0K0.00%−3,646−22.6%Reduced
Boothbay Fund Management, LLC11,825$423.2K0.01%00.0%Unchanged
Two Sigma Investments, LP11,454$409.9K0.00%+11,454New
Supplemental Annuity Collective Trust of NJ11,000$393.7K0.15%00.0%Unchanged
Bayesian Capital Management, LP10,900$390.1K0.05%+10,900New
Public Employees Retirement Association of Colorado10,633$381.0K0.00%00.0%Unchanged
Stifel Financial Corp10,304$368.8K0.00%+360+3.6%Added
Virginia Retirement Systems Et Al10,300$368.6K0.00%−2,200−17.6%Reduced
Birchview Capital, LP10,000$358.0K0.28%00.0%Unchanged
American Century Companies Inc9,474$337.4K0.00%−1,531−13.9%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)9,307$333.1K0.00%−132−1.4%Reduced
Susquehanna Fundamental Investments, LLC8,400$300.6K0.01%−20,263−70.7%Reduced
Advisors Asset Management, Inc.8,392$300.4K0.01%+546+7.0%Added
Walleye Trading LLC8,011$286.7K0.01%+8,011New
Citigroup Inc7,817$279.8K0.00%+6,008+332.1%Added
Connacht Asset Management LP6,391$228.7K0.66%+6,391New
Jane Street Group, LLC5,666$202.8K0.00%−9,624−62.9%Reduced
Northwestern Mutual Wealth Management Co5,000$178.9K0.00%00.0%Unchanged
UBS Group AG4,614$165.1K0.00%−48−1.0%Reduced
Wells Fargo & Company3,946$141.2K0.00%+2,823+251.4%Added
Kapitalo Investimentos Ltda3,612$129.3K0.04%+3,612New
Values First Advisors, Inc.3,498$125.2K0.08%+3,498New
Virtus ETF Advisers LLC2,610$93.4K0.05%−1,006−27.8%Reduced
Deutsche Bank AG2,495$89.3K0.00%00.0%Unchanged
Dark Forest Capital Management LP2,455$87.9K0.02%+2,455New
Great West Life Assurance Co2,392$86.0K0.00%00.0%Unchanged
Aquatic Capital Management LLC2,000$72.0K0.00%+2,000New
Proequities, Inc.2,000$71.6K0.01%00.0%Unchanged
Cubist Systematic Strategies, LLC1,955$70.0K0.00%+1,778+1,004.5%Added
BNP Paribas Arbitrage, SA1,028$36.8K0.00%−498−32.6%Reduced
China Universal Asset Management Co., Ltd.848$30.4K0.01%+213+33.5%Added
Advisor Group Holdings, Inc.682$24.4K0.00%+6+0.9%Added
Leonteq Securities AG530$19.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)511$18.0K0.00%−2,041−80.0%Reduced
Householder Group Estate & Retirement Specialist, LLC283$10.0K0.00%+8+2.9%Added
Daiwa Securities Group Inc.252$9.00K0.00%00.0%Unchanged
First Horizon Advisors, Inc.200$7.16K0.00%+200New
IFP Advisors, Inc1,000$5.70K0.00%00.0%Unchanged
Barclays PLC100$3.58K0.00%+100New
Hexagon Capital Partners LLC82$2.94K0.00%−27−24.8%Reduced
Belpointe Asset Management LLC70$2.50K0.00%00.0%Unchanged
Signaturefd, LLC33$1.18K0.00%+33New
Mirabella Financial Services LLP11,802––−19,657−62.5%Reduced
Balyasny Asset Management LLC0$00.00%−162,828−100.0%Sold out
EAM Global Investors LLC0$00.00%−146,387−100.0%Sold out
Twinbeech Capital LP0$00.00%−101,717−100.0%Sold out
LMR Partners LLP0$00.00%−50,000−100.0%Sold out
Cheyne Capital Management (UK) LLP0$00.00%−42,500−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−38,000−100.0%Sold out
Scotia Capital Inc.0$00.00%−26,859−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−22,700−100.0%Sold out
Ameriprise Financial Inc0$00.00%−22,626−100.0%Sold out
Sanders Morris Harris LLC0$00.00%−21,500−100.0%Sold out
Velan Capital Investment Management LP0$00.00%−20,000−100.0%Sold out
Jefferies Financial Group Inc.0$00.00%−19,500−100.0%Sold out
Employees Retirement System of Texas0$00.00%−16,001−100.0%Sold out
Engineers Gate Manager LP0$00.00%−14,383−100.0%Sold out
Ergoteles LLC0$00.00%−13,516−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−12,975−100.0%Sold out
Main Street Research LLC0$00.00%−10,000−100.0%Sold out
Jump Financial, LLC0$00.00%−7,725−100.0%Sold out
Group One Trading, L.P.0$00.00%−6,552−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−5,799−100.0%Sold out
Virtu Financial LLC0$00.00%−5,604−100.0%Sold out
ProShare Advisors LLC0$00.00%−5,172−100.0%Sold out
High Net Worth Advisory Group LLC0$00.00%−2,000−100.0%Sold out
Cutler Group LP0$00.00%−100−100.0%Sold out
Ronald Blue Trust, Inc.0$00.00%−29−100.0%Sold out