Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2025
Institutional positions in Xenon Pharmaceuticals Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 206
- −3 vs. Q4 2024
- Shares held
- 76.7M
- +410.6K (+0.5%) vs. Q4 2024
- Total value
- $2.58B
- −$414.7M (−13.9%) vs. Q4 2024
- New holders
- 20
- 69 more added
- Sold out
- 23
- 73 more reduced
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 8,287,499 | $278.0M | 0.02% | +762,209+10.1% | Added |
| Avoro Capital Advisors LLC | 5,741,666 | $192.6M | 3.01% | +75,000+1.3% | Added |
| Driehaus Capital Management LLC | 4,584,859 | $153.8M | 1.48% | +64,264+1.4% | Added |
| Wellington Management Group LLP | 3,789,197 | $127.1M | 0.02% | +11,586+0.3% | Added |
| Janus Henderson Group PLC | 3,325,093 | $113.9M | 0.06% | +458,338+16.0% | Added |
| Capital International Investors | 3,088,730 | $103.6M | 0.02% | +541,520+21.3% | Added |
| Braidwell LP | 2,709,875 | $90.9M | 3.20% | −204,089−7.0% | Reduced |
| Polar Capital Holdings Plc | 2,623,039 | $88.0M | 0.54% | −74,618−2.8% | Reduced |
| Commodore Capital LP | 2,325,000 | $78.0M | 5.75% | −415,000−15.1% | Reduced |
| Capital World Investors | 2,224,715 | $74.6M | 0.01% | −69,822−3.0% | Reduced |
| BlackRock, Inc. | 2,036,125 | $68.3M | 0.00% | −69,111−3.3% | Reduced |
| Adage Capital Partners GP, L.L.C. | 1,914,749 | $64.2M | 0.12% | +51,276+2.8% | Added |
| Pictet Asset Management Holding SA | 1,477,617 | $49.6M | 0.06% | −18,894−1.3% | Reduced |
| Westfield Capital Management Co LP | 1,391,370 | $46.7M | 0.23% | +234,181+20.2% | Added |
| JPMorgan Chase & Co | 1,357,602 | $45.5M | 0.00% | +707+0.1% | Added |
| Alliancebernstein L.P. | 1,329,386 | $44.6M | 0.02% | −113,794−7.9% | Reduced |
| Affinity Asset Advisors, LLC | 1,328,175 | $44.6M | 6.98% | +166,938+14.4% | Added |
| Vestal Point Capital, LP | 1,300,000 | $43.6M | 3.11% | +490,000+60.5% | Added |
| Samlyn Capital, LLC | 1,016,381 | $34.1M | 0.56% | −1,457−0.1% | Reduced |
| Deep Track Capital, LP | 1,000,000 | $33.5M | 1.09% | +830,868+491.3% | Added |
| OrbiMed Advisors LLC | 947,877 | $31.8M | 0.76% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 931,681 | $31.3M | 1.79% | −320,178−25.6% | Reduced |
| T. Rowe Price Investment Management, Inc. | 796,986 | $26.7M | 0.02% | −640,845−44.6% | Reduced |
| Jennison Associates LLC | 776,693 | $26.1M | 0.02% | −24,860−3.1% | Reduced |
| Marshall Wace, LLP | 758,145 | $25.4M | 0.03% | −141,573−15.7% | Reduced |
| TimesSquare Capital Management, LLC | 745,551 | $25.0M | 0.40% | −103,299−12.2% | Reduced |
| Siren, L.L.C. | 732,761 | $24.6M | 1.39% | −11,008−1.5% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 703,795 | $23.6M | 0.06% | +40,091+6.0% | Added |
| Citadel Advisors LLC | 687,088 | $23.1M | 0.02% | +359,785+109.9% | Added |
| First Turn Management, LLC | 683,451 | $22.9M | 4.62% | −1,535−0.2% | Reduced |
| Loomis Sayles & Co L P | 673,011 | $22.6M | 0.03% | −14,134−2.1% | Reduced |
| Logos Global Management LP | 650,000 | $21.8M | 3.88% | +650,000 | New |
| First Light Asset Management, LLC | 627,904 | $21.1M | 2.41% | −532,676−45.9% | Reduced |
| Boxer Capital Management, LLC | 600,000 | $20.1M | 6.05% | 00.0% | Unchanged |
| Fiera Capital Corp | 529,442 | $17.8M | 0.06% | −6,445−1.2% | Reduced |
| Franklin Resources Inc | 491,120 | $16.5M | 0.00% | −84,470−14.7% | Reduced |
| Candriam Luxembourg S.C.A. | 454,650 | $15.3M | 0.10% | −37,531−7.6% | Reduced |
| Goldman Sachs Group Inc | 442,732 | $14.9M | 0.00% | +32,486+7.9% | Added |
| Saturn V Capital Management LLC | 413,711 | $13.9M | 7.00% | +91,241+28.3% | Added |
| Standard Life Aberdeen plc | 404,154 | $13.6M | 0.03% | +120,255+42.4% | Added |
| Alyeska Investment Group, L.P. | 367,233 | $12.3M | 0.05% | +78,390+27.1% | Added |
| Baker Bros. Advisors LP | 347,408 | $11.7M | 0.13% | −646,271−65.0% | Reduced |
| Vanguard Group Inc | 336,514 | $11.3M | 0.00% | −6,265−1.8% | Reduced |
| Perceptive Advisors LLC | 325,324 | $10.9M | 0.39% | 00.0% | Unchanged |
| State Street Corp | 305,620 | $10.3M | 0.00% | +16,898+5.9% | Added |
| MPM Oncology Impact Management LP | 303,398 | $10.2M | 1.75% | +106,186+53.8% | Added |
| Two Sigma Advisers, LP | 298,800 | $10.0M | 0.02% | +1000.0% | Added |
| StemPoint Capital LP | 274,633 | $9.21M | 2.94% | −101,212−26.9% | Reduced |
| DAFNA Capital Management LLC | 273,739 | $9.18M | 2.60% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 267,142 | $8.96M | 0.02% | +82,562+44.7% | Added |
| Bank of New York Mellon Corp | 251,147 | $8.43M | 0.00% | +204,550+439.0% | Added |
| Great Point Partners LLC | 245,272 | $8.23M | 4.47% | 00.0% | Unchanged |
| Assenagon Asset Management S.A. | 241,206 | $8.09M | 0.01% | +2,684+1.1% | Added |
| Two Sigma Investments, LP | 236,983 | $7.95M | 0.02% | −36,369−13.3% | Reduced |
| Millennium Management LLC | 234,056 | $7.85M | 0.01% | −111,984−32.4% | Reduced |
| Federated Hermes, Inc. | 232,500 | $7.80M | 0.02% | −326,000−58.4% | Reduced |
| DnB Asset Management AS | 229,482 | $7.70M | 0.04% | +26,239+12.9% | Added |
| Avidity Partners Management LP | 229,000 | $7.68M | 1.58% | −245,000−51.7% | Reduced |
| Dimensional Fund Advisors LP | 214,860 | $7.21M | 0.00% | −45,110−17.4% | Reduced |
| Point72 Asset Management, L.P. | 209,759 | $7.04M | 0.02% | +209,759 | New |
| Invesco Ltd. | 205,763 | $6.90M | 0.00% | −3,791−1.8% | Reduced |
| Granahan Investment Management Inc | 183,808 | $6.17M | 0.31% | +1,475+0.8% | Added |
| AXA S.A. | 175,350 | $5.88M | 0.02% | −12,446−6.6% | Reduced |
| Parkman Healthcare Partners LLC | 174,576 | $5.86M | 0.69% | −18,428−9.5% | Reduced |
| Nan Fung Group Holdings Ltd | 158,605 | $5.32M | 4.34% | +51,925+48.7% | Added |
| Renaissance Technologies LLC | 154,700 | $5.19M | 0.01% | +141,000+1,029.2% | Added |
| D. E. Shaw & Co., Inc. | 152,188 | $5.11M | 0.01% | +65,215+75.0% | Added |
| Bridger Management, LLC | 146,800 | $4.93M | 2.45% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 142,372 | $4.78M | 0.01% | +9,851+7.4% | Added |
| Schroder Investment Management Group | 137,221 | $4.70M | 0.00% | −39,453−22.3% | Reduced |
| Bank of America Corp | 136,569 | $4.58M | 0.00% | +29,663+27.7% | Added |
| Morgan Stanley | 129,491 | $4.34M | 0.00% | +61,429+90.3% | Added |
| ADAR1 Capital Management, LLC | 127,548 | $4.28M | 0.82% | +77,001+152.3% | Added |
| Swiss National Bank | 125,600 | $4.21M | 0.00% | −1,000−0.8% | Reduced |
| Algert Global LLC | 123,415 | $4.14M | 0.10% | −118,002−48.9% | Reduced |
| UBS Group AG | 105,333 | $3.53M | 0.00% | +98,628+1,471.0% | Added |
| Ameriprise Financial Inc | 103,624 | $3.48M | 0.00% | +11,274+12.2% | Added |
| Bamco Inc | 100,100 | $3.36M | 0.01% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 97,149 | $3.26M | 0.01% | +565+0.6% | Added |
| PFM Health Sciences, LP | 92,236 | $3.09M | 0.24% | −24,762−21.2% | Reduced |
| Lord, Abbett & Co. LLC | 87,981 | $2.95M | 0.01% | −106,990−54.9% | Reduced |
| Nicholas Investment Partners, LP | 86,968 | $2.92M | 0.30% | +72,310+493.3% | Added |
| Northern Trust Corp | 81,024 | $2.72M | 0.00% | +15,241+23.2% | Added |
| Russell Investments Group, Ltd. | 75,341 | $2.53M | 0.00% | −138,355−64.7% | Reduced |
| Ally Bridge Group (NY) LLC | 69,603 | $2.34M | 2.11% | −59,688−46.2% | Reduced |
| Geode Capital Management, LLC | 69,597 | $2.33M | 0.00% | +68+0.1% | Added |
| HighVista Strategies LLC | 66,788 | $2.24M | 0.86% | 00.0% | Unchanged |
| Wells Fargo & Company | 65,912 | $2.21M | 0.00% | +6,392+10.7% | Added |
| UBS Asset Management Americas Inc | 63,568 | $2.13M | 0.00% | −128,284−66.9% | Reduced |
| Raymond James Financial Inc | 63,385 | $2.13M | 0.00% | +43,054+211.8% | Added |
| Legal & General Group Plc | 60,406 | $2.03M | 0.00% | 00.0% | Unchanged |
| Altium Capital Management LP | 60,251 | $2.02M | 5.87% | −227,749−79.1% | Reduced |
| Royal Bank of Canada | 59,366 | $1.99M | 0.00% | −702−1.2% | Reduced |
| Harbor Capital Advisors, Inc. | 56,591 | $1.90M | 0.09% | +6,773+13.6% | Added |
| California State Teachers Retirement System | 55,492 | $1.86M | 0.00% | 00.0% | Unchanged |
| Alps Advisors Inc | 55,332 | $1.86M | 0.01% | −6,316−10.2% | Reduced |
| Moore Capital Management, LP | 55,000 | $1.85M | 0.06% | 00.0% | Unchanged |
| Deutsche Bank AG | 53,711 | $1.80M | 0.00% | 00.0% | Unchanged |
| Erste Asset Management GmbH | 50,000 | $1.71M | 0.02% | 00.0% | Unchanged |
| State of New Jersey Common Pension Fund D | 50,417 | $1.69M | 0.01% | −3,616−6.7% | Reduced |