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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2024

Institutional positions in Xenon Pharmaceuticals Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
203
−9 vs. Q2 2024
Shares held
74.9M
+2.82M (+3.9%) vs. Q2 2024
Total value
$2.95B
+$139.5M (+5.0%) vs. Q2 2024
New holders
15
75 more added
Sold out
24
62 more reduced

1 institution that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 203 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ3 2024: $2.95B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q2 2024.

Institutions holding XENE in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC6,917,684$272.3M0.02%+149,511+2.2%Added
Avoro Capital Advisors LLC5,666,666$223.1M3.25%00.0%Unchanged
Driehaus Capital Management LLC4,595,721$180.9M1.55%+176,249+4.0%Added
Wellington Management Group LLP3,843,447$151.3M0.03%+15,226+0.4%Added
Braidwell LP2,707,255$106.6M3.02%+146,682+5.7%Added
Commodore Capital LP2,700,000$106.3M6.64%−54,266−2.0%Reduced
Capital World Investors2,681,537$105.6M0.02%00.0%Unchanged
Capital International Investors2,581,172$101.6M0.02%+105,313+4.3%Added
Janus Henderson Group PLC2,552,392$100.5M0.05%+1,507,135+144.2%Added
Polar Capital Holdings Plc2,444,645$96.2M0.57%−91,413−3.6%Reduced
BlackRock, Inc.2,105,562$82.9M0.00%+2,105,562New
Adage Capital Partners GP, L.L.C.2,083,972$82.0M0.14%+244,417+13.3%Added
Pictet Asset Management Holding SA1,528,814$60.2M0.07%+49,323+3.3%Added
T. Rowe Price Investment Management, Inc.1,503,808$59.2M0.04%+63,905+4.4%Added
Alliancebernstein L.P.1,424,735$56.1M0.02%−58,431−3.9%Reduced
Rock Springs Capital Management LP1,316,477$51.8M1.69%+43,600+3.4%Added
Marshall Wace, LLP1,195,480$47.1M0.06%−189,194−13.7%Reduced
First Light Asset Management, LLC1,181,662$46.5M3.87%−124,598−9.5%Reduced
Affinity Asset Advisors, LLC1,144,021$45.0M6.99%+149,794+15.1%Added
Samlyn Capital, LLC1,020,206$40.2M0.65%+380,521+59.5%Added
Baker Bros. Advisors LP993,679$39.1M0.41%00.0%Unchanged
JPMorgan Chase & Co976,783$38.5M0.00%+905,129+1,263.2%Added
OrbiMed Advisors LLC911,420$35.9M0.66%+49,058+5.7%Added
Vestal Point Capital, LP825,000$32.5M2.56%+300,000+57.1%Added
Avidity Partners Management LP818,000$32.2M1.64%+64,000+8.5%Added
TimesSquare Capital Management, LLC778,293$30.6M0.46%+23,800+3.2%Added
Siren, L.L.C.743,769$29.3M1.47%+743,769New
Federated Hermes, Inc.736,200$29.0M0.06%+1,645+0.2%Added
Citadel Advisors LLC722,504$28.4M0.03%−46,222−6.0%Reduced
Loomis Sayles & Co L P707,222$27.8M0.04%+46,964+7.1%Added
Westfield Capital Management Co LP669,600$26.4M0.12%+26,054+4.0%Added
Franklin Resources Inc565,915$23.6M0.01%−12,950−2.2%Reduced
Boxer Capital, LLC600,000$23.6M1.16%00.0%Unchanged
Jennison Associates LLC576,661$22.7M0.01%+6,389+1.1%Added
Fiera Capital Corp554,200$21.8M0.07%−28,679−4.9%Reduced
Perceptive Advisors LLC524,930$20.7M0.44%−58,326−10.0%Reduced
Candriam Luxembourg S.C.A.463,861$18.3M0.10%−57,975−11.1%Reduced
Goldman Sachs Group Inc459,625$18.1M0.00%+95,452+26.2%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.439,074$17.3M0.04%+17,953+4.3%Added
Point72 Asset Management, L.P.383,290$15.1M0.05%−98,732−20.5%Reduced
Altium Capital Management LP360,600$14.2M4.23%00.0%Unchanged
Vanguard Group Inc344,365$13.6M0.00%+3,213+0.9%Added
First Turn Management, LLC325,218$12.8M2.03%−14,658−4.3%Reduced
Dimensional Fund Advisors LP299,865$11.8M0.00%−136,595−31.3%Reduced
Alyeska Investment Group, L.P.288,843$11.4M0.06%−3,025−1.0%Reduced
State Street Corp279,513$11.0M0.00%+32,701+13.2%Added
DAFNA Capital Management LLC273,739$10.8M2.55%00.0%Unchanged
Two Sigma Advisers, LP273,700$10.8M0.03%+64,800+31.0%Added
ExodusPoint Capital Management, LP262,631$10.3M0.11%−94,547−26.5%Reduced
Standard Life Aberdeen plc248,311$9.78M0.02%+35,809+16.9%Added
Two Sigma Investments, LP243,579$9.59M0.02%+48,450+24.8%Added
Morgan Stanley239,942$9.45M0.00%+1,170+0.5%Added
Russell Investments Group, Ltd.223,614$8.80M0.01%+60,764+37.3%Added
Algert Global LLC219,645$8.65M0.23%+36,440+19.9%Added
Invesco Ltd.215,822$8.50M0.00%−650,963−75.1%Reduced
Assenagon Asset Management S.A.212,287$8.36M0.02%+138,685+188.4%Added
Ally Bridge Group (NY) LLC211,791$8.34M4.46%+42,422+25.0%Added
Millennium Management LLC209,026$8.23M0.01%+33,442+19.0%Added
D. E. Shaw & Co., Inc.204,892$8.07M0.01%+43,170+26.7%Added
Granahan Investment Management Inc200,877$7.91M0.31%−25,289−11.2%Reduced
Parkman Healthcare Partners LLC191,658$7.55M0.96%−17,632−8.4%Reduced
DnB Asset Management AS190,623$7.50M0.03%+14,890+8.5%Added
AXA S.A.188,090$7.41M0.02%+520.0%Added
PFM Health Sciences, LP179,878$7.08M0.41%+29,324+19.5%Added
Lord, Abbett & Co. LLC173,985$6.85M0.02%−16,048−8.4%Reduced
Schroder Investment Management Group176,674$6.83M0.01%+85,174+93.1%Added
MPM Oncology Impact Management LP165,800$6.53M0.98%+165,800New
Ensign Peak Advisors, Inc163,064$6.42M0.01%00.0%Unchanged
UBS Asset Management Americas Inc162,683$6.40M0.00%+217+0.1%Added
Bridger Management, LLC146,800$5.78M2.89%00.0%Unchanged
New York State Common Retirement Fund132,521$5.22M0.01%−18,319−12.1%Reduced
Bank of America Corp127,456$5.02M0.00%−14,876−10.5%Reduced
Atika Capital Management LLC126,000$4.96M0.53%+2,000+1.6%Added
Swiss National Bank125,300$4.93M0.00%−800−0.6%Reduced
Ikarian Capital, LLC107,187$4.22M1.31%00.0%Unchanged
Nan Fung Group Holdings Ltd106,680$4.20M3.62%00.0%Unchanged
Walleye Capital LLC104,960$4.13M0.04%+104,960New
State of Wisconsin Investment Board100,982$3.98M0.01%+11,182+12.5%Added
Bamco Inc100,100$3.94M0.01%00.0%Unchanged
Balyasny Asset Management LLC84,198$3.31M0.01%−149,137−63.9%Reduced
HighVista Strategies LLC73,762$2.90M1.00%+1,047+1.4%Added
Geode Capital Management, LLC68,809$2.71M0.00%−120−0.2%Reduced
Jefferies Financial Group Inc.66,500$2.62M0.04%−2,500−3.6%Reduced
Ameriprise Financial Inc66,383$2.61M0.00%+66,383New
Wells Fargo & Company60,456$2.38M0.00%+1,389+2.4%Added
Alps Advisors Inc56,989$2.24M0.02%−1,864−3.2%Reduced
California State Teachers Retirement System56,004$2.20M0.00%−2,136−3.7%Reduced
Legal & General Group Plc55,120$2.17M0.00%00.0%Unchanged
Moore Capital Management, LP55,000$2.17M0.06%00.0%Unchanged
Deutsche Bank AG53,711$2.11M0.00%00.0%Unchanged
Erste Asset Management GmbH50,000$1.93M0.02%00.0%Unchanged
Bank of New York Mellon Corp48,891$1.92M0.00%−2,363−4.6%Reduced
Envestnet Asset Management Inc48,836$1.92M0.00%−110−0.2%Reduced
LMR Partners LLP48,668$1.92M0.04%00.0%Unchanged
State of New Jersey Common Pension Fund D48,573$1.91M0.01%00.0%Unchanged
Harbor Capital Advisors, Inc.48,063$1.89M0.08%+23,947+99.3%Added
Voya Investment Management LLC47,165$1.86M0.00%00.0%Unchanged
Jump Financial, LLC45,000$1.77M0.04%−3,166−6.6%Reduced
Renaissance Technologies LLC44,000$1.73M0.00%−48,900−52.6%Reduced
Northern Trust Corp43,406$1.71M0.00%−3,446−7.4%Reduced