Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2022
Institutional positions in Xenon Pharmaceuticals Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 154
- +3 vs. Q2 2022
- Shares held
- 57.9M
- +880.8K (+1.5%) vs. Q2 2022
- Total value
- $2.09B
- +$355.6M (+20.5%) vs. Q2 2022
- New holders
- 26
- 58 more added
- Sold out
- 23
- 42 more reduced
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 4,900,000 | $176.9M | 3.27% | 00.0% | Unchanged |
| FMR LLC | 4,669,759 | $168.6M | 0.02% | +97,391+2.1% | Added |
| Driehaus Capital Management LLC | 4,504,020 | $162.6M | 2.46% | +112,982+2.6% | Added |
| Marshall Wace, LLP | 2,811,095 | $101.5M | 0.25% | +820,723+41.2% | Added |
| Polar Capital Holdings Plc | 2,662,722 | $96.1M | 0.78% | +122,663+4.8% | Added |
| Redmile Group, LLC | 2,370,614 | $85.6M | 3.32% | +731,270+44.6% | Added |
| Pictet Asset Management SA | 2,287,365 | $82.6M | 0.12% | +467,889+25.7% | Added |
| Capital World Investors | 2,274,974 | $82.1M | 0.02% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 2,122,535 | $76.6M | 2.23% | 00.0% | Unchanged |
| Lord, Abbett & Co. LLC | 1,913,861 | $69.1M | 0.25% | +56,265+3.0% | Added |
| Holocene Advisors, LP | 1,829,152 | $66.0M | 0.42% | 00.0% | Unchanged |
| Capital International Investors | 1,642,508 | $59.3M | 0.02% | +60,000+3.8% | Added |
| Point72 Asset Management, L.P. | 1,640,072 | $59.2M | 0.26% | +738,566+81.9% | Added |
| Commodore Capital LP | 1,594,932 | $57.6M | 9.26% | 00.0% | Unchanged |
| Samlyn Capital, LLC | 1,289,233 | $46.5M | 0.89% | +172,797+15.5% | Added |
| Rock Springs Capital Management LP | 1,155,961 | $41.7M | 1.08% | +32,357+2.9% | Added |
| Citadel Advisors LLC | 1,142,002 | $41.2M | 0.05% | −506,037−30.7% | Reduced |
| OrbiMed Advisors LLC | 1,137,300 | $41.1M | 0.82% | −191,900−14.4% | Reduced |
| BlackRock Inc. | 1,042,529 | $37.6M | 0.00% | +174,239+20.1% | Added |
| BVF Inc | 901,095 | $32.5M | 1.34% | −696,871−43.6% | Reduced |
| Great Point Partners LLC | 850,000 | $30.7M | 7.39% | −254,334−23.0% | Reduced |
| Candriam Luxembourg S.C.A. | 760,884 | $27.5M | 0.19% | −102,256−11.8% | Reduced |
| Baker Bros. Advisors LP | 751,639 | $27.1M | 0.18% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 675,000 | $24.4M | 0.06% | +45,000+7.1% | Added |
| Eventide Asset Management, LLC | 641,200 | $23.1M | 0.46% | +171,500+36.5% | Added |
| Boxer Capital, LLC | 600,000 | $21.7M | 1.22% | 00.0% | Unchanged |
| Millennium Management LLC | 560,349 | $20.2M | 0.03% | +67,658+13.7% | Added |
| Logos Global Management LP | 500,000 | $18.1M | 2.23% | +500,000 | New |
| Goldman Sachs Group Inc | 465,265 | $16.8M | 0.00% | +168,951+57.0% | Added |
| Bank of New York Mellon Corp | 437,645 | $15.8M | 0.00% | −125,542−22.3% | Reduced |
| D. E. Shaw & Co., Inc. | 409,563 | $14.8M | 0.03% | +83,021+25.4% | Added |
| Woodline Partners LP | 404,359 | $14.6M | 0.21% | +175,431+76.6% | Added |
| DAFNA Capital Management LLC | 375,223 | $13.5M | 3.64% | −63,400−14.5% | Reduced |
| Dimensional Fund Advisors LP | 342,031 | $12.3M | 0.00% | +167,069+95.5% | Added |
| Granahan Investment Management Inc | 299,855 | $10.8M | 0.35% | +15,083+5.3% | Added |
| Acuta Capital Partners, LLC | 272,500 | $9.84M | 4.38% | 00.0% | Unchanged |
| Eversept Partners, LP | 259,612 | $9.37M | 1.11% | −206,299−44.3% | Reduced |
| Silverarc Capital Management, LLC | 245,992 | $8.88M | 3.77% | +13,362+5.7% | Added |
| Janus Henderson Group PLC | 233,834 | $8.43M | 0.01% | −42,840−15.5% | Reduced |
| Parkman Healthcare Partners LLC | 222,597 | $8.04M | 2.28% | −71,962−24.4% | Reduced |
| State of Wisconsin Investment Board | 217,474 | $7.85M | 0.02% | +171,651+374.6% | Added |
| AXA S.A. | 191,836 | $6.93M | 0.03% | +485+0.3% | Added |
| Vanguard Group Inc | 185,192 | $6.69M | 0.00% | +1,347+0.7% | Added |
| State Street Corp | 170,371 | $6.15M | 0.00% | −26,850−13.6% | Reduced |
| Ikarian Capital, LLC | 160,486 | $5.79M | 2.89% | −78,955−33.0% | Reduced |
| Morgan Stanley | 158,452 | $5.72M | 0.00% | −839,620−84.1% | Reduced |
| EAM Global Investors LLC | 154,485 | $5.58M | 1.48% | +3,996+2.7% | Added |
| Balyasny Asset Management LLC | 147,355 | $5.32M | 0.02% | +147,355 | New |
| Alliancebernstein L.P. | 142,726 | $5.15M | 0.00% | −287,234−66.8% | Reduced |
| Tri Locum Partners LP | 134,331 | $4.85M | 1.38% | −32,068−19.3% | Reduced |
| Putnam Investments LLC | 129,284 | $4.67M | 0.01% | +129,284 | New |
| Nan Fung Group Holdings Ltd | 114,380 | $4.13M | 2.64% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 113,480 | $4.10M | 0.01% | +57,189+101.6% | Added |
| Swiss National Bank | 108,400 | $3.91M | 0.00% | +600+0.6% | Added |
| Schonfeld Strategic Advisors LLC | 108,284 | $3.91M | 0.03% | −19,825−15.5% | Reduced |
| Moore Capital Management, LP | 102,977 | $3.72M | 0.10% | −69,094−40.2% | Reduced |
| Russell Investments Group, Ltd. | 99,074 | $3.58M | 0.01% | −8,825−8.2% | Reduced |
| Soleus Capital Management, L.P. | 96,800 | $3.49M | 0.47% | +21,800+29.1% | Added |
| Two Sigma Advisers, LP | 91,000 | $3.29M | 0.01% | +38,700+74.0% | Added |
| Walleye Capital LLC | 87,971 | $3.18M | 0.07% | −73,956−45.7% | Reduced |
| Voya Investment Management LLC | 67,140 | $2.42M | 0.00% | +67,140 | New |
| LMR Partners LLP | 65,698 | $2.37M | 0.06% | −34,302−34.3% | Reduced |
| State of New Jersey Common Pension Fund D | 64,454 | $2.33M | 0.01% | +64,454 | New |
| Geode Capital Management, LLC | 61,823 | $2.23M | 0.00% | +16,307+35.8% | Added |
| Tekla Capital Management LLC | 61,733 | $2.23M | 0.09% | +32,023+107.8% | Added |
| Knott David M Jr | 59,500 | $2.15M | 1.01% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 55,974 | $2.02M | 0.01% | +55,974 | New |
| UBS Oconnor LLC | 54,208 | $1.96M | 0.02% | −42,000−43.7% | Reduced |
| Jump Financial, LLC | 53,300 | $1.92M | 0.07% | +53,300 | New |
| Northern Trust Corp | 50,891 | $1.84M | 0.00% | +2,895+6.0% | Added |
| Nuveen Asset Management, LLC | 50,360 | $1.82M | 0.00% | +6,049+13.7% | Added |
| Twinbeech Capital LP | 48,750 | $1.76M | 0.05% | +37,727+342.3% | Added |
| Bridger Management, LLC | 45,235 | $1.63M | 0.49% | −32,165−41.6% | Reduced |
| Algert Global LLC | 45,246 | $1.63M | 0.10% | +18,842+71.4% | Added |
| Fred Alger Management, LLC | 45,143 | $1.63M | 0.01% | +45,143 | New |
| Credit Suisse AG | 43,653 | $1.58M | 0.00% | +10,469+31.5% | Added |
| Jane Street Group, LLC | 41,912 | $1.51M | 0.00% | +41,912 | New |
| Ameriprise Financial Inc | 41,144 | $1.49M | 0.00% | −10,032−19.6% | Reduced |
| California State Teachers Retirement System | 39,347 | $1.42M | 0.00% | +316+0.8% | Added |
| UBS Asset Management Americas Inc | 38,404 | $1.39M | 0.00% | +11,496+42.7% | Added |
| Advisory Research Inc | 36,438 | $1.32M | 0.13% | +1,438+4.1% | Added |
| Erste Asset Management GmbH | 35,000 | $1.26M | 0.03% | 00.0% | Unchanged |
| Qube Research & Technologies Ltd | 34,483 | $1.25M | 0.01% | +34,483 | New |
| Scotia Capital Inc. | 34,251 | $1.24M | 0.01% | −3,223−8.6% | Reduced |
| Alps Advisors Inc | 33,959 | $1.23M | 0.01% | +2,461+7.8% | Added |
| Susquehanna Fundamental Investments, LLC | 33,181 | $1.20M | 0.02% | +33,181 | New |
| Kynam Capital Management, LP | 28,792 | $1.04M | 0.22% | −146,208−83.5% | Reduced |
| Bamco Inc | 27,500 | $993.0K | 0.00% | +5,500+25.0% | Added |
| Bank of America Corp | 26,995 | $974.0K | 0.00% | −9,660−26.4% | Reduced |
| International Biotechnology Trust PLC | 25,500 | $918.0K | 0.29% | +24,726+3,194.6% | Added |
| NJ State Employees Deferred Compensation Plan | 25,000 | $903.0K | 0.15% | 00.0% | Unchanged |
| Difesa Capital Management, LP | 24,500 | $884.0K | 0.65% | +24,500 | New |
| CIBC World Markets Inc. | 23,300 | $841.0K | 0.00% | −23,587−50.3% | Reduced |
| HighVista Strategies LLC | 22,572 | $815.0K | 0.47% | +137+0.6% | Added |
| Chartwell Investment Partners, LLC | 22,289 | $805.0K | 0.03% | +781+3.6% | Added |
| SG Americas Securities, LLC | 21,832 | $788.0K | 0.01% | −621−2.8% | Reduced |
| Natixis Advisors, L.P. | 21,603 | $780.0K | 0.00% | +2,224+11.5% | Added |
| Sanders Morris Harris LLC | 21,500 | $778.0K | 0.19% | −3,000−12.2% | Reduced |
| Cubist Systematic Strategies, LLC | 20,211 | $730.0K | 0.01% | −32,467−61.6% | Reduced |
| Allianz Asset Management GmbH | 20,000 | $722.0K | 0.00% | −68,630−77.4% | Reduced |