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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2022

Institutional positions in Xenon Pharmaceuticals Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
154
+3 vs. Q2 2022
Shares held
57.9M
+880.8K (+1.5%) vs. Q2 2022
Total value
$2.09B
+$355.6M (+20.5%) vs. Q2 2022
New holders
26
58 more added
Sold out
23
42 more reduced

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 154 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ3 2022: $2.09B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q2 2022.

Institutions holding XENE in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Royal Bank of Canada1$00.00%+1New
Cutler Group LP100$3.00K0.00%+100New
IFP Advisors, Inc1,000$6.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.198$7.00K0.00%00.0%Unchanged
Hexagon Capital Partners LLC197$7.00K0.00%+197New
Householder Group Estate & Retirement Specialist, LLC275$9.00K0.00%+275New
Simplex Trading, LLC432$15.0K0.00%−508−54.0%Reduced
Wells Fargo & Company500$18.0K0.00%+500New
Leonteq Securities AG530$19.1K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.583$21.0K0.01%+583New
Advisor Group Holdings, Inc.591$22.0K0.00%+328+124.7%Added
Macquarie Group Ltd132$24.0K0.00%−539−80.3%Reduced
High Net Worth Advisory Group LLC1,000$36.0K0.02%00.0%Unchanged
Quantbot Technologies LP1,300$46.0K0.00%+1,300New
Citigroup Inc1,717$62.0K0.00%−201−10.5%Reduced
Proequities, Inc.2,000$72.0K0.01%00.0%Unchanged
Great West Life Assurance Co2,392$86.0K0.00%+535+28.8%Added
UBS Group AG3,426$123.0K0.00%+954+38.6%Added
Amundi3,581$133.0K0.00%00.0%Unchanged
Virtus ETF Advisers LLC3,673$133.0K0.05%+30+0.8%Added
Advisors Asset Management, Inc.4,121$149.0K0.00%−927−18.4%Reduced
Tower Research Capital LLC (TRC)4,200$151.0K0.00%+2,738+187.3%Added
JPMorgan Chase & Co4,271$155.0K0.00%+1,825+74.6%Added
BNP Paribas Arbitrage, SA4,956$178.9K0.00%+2,212+80.6%Added
Walleye Trading LLC5,603$202.0K0.01%+5,603New
Zurcher Kantonalbank (Zurich Cantonalbank)6,667$241.0K0.00%00.0%Unchanged
American Century Companies Inc6,670$241.0K0.00%+6,670New
Occudo Quantitative Strategies LP7,263$262.0K0.02%−3,682−33.6%Reduced
Engineers Gate Manager LP9,717$351.0K0.02%−13,030−57.3%Reduced
Fox Run Management, L.L.C.9,731$351.0K0.14%+9,731New
Main Street Research LLC10,000$361.0K0.08%00.0%Unchanged
Birchview Capital, LP10,000$361.0K0.25%00.0%Unchanged
Dynamic Technology Lab Private Ltd9,990$361.0K0.04%+9,990New
Stifel Financial Corp10,044$363.0K0.00%00.0%Unchanged
Handelsbanken Fonder AB10,600$383.0K0.00%−4,600−30.3%Reduced
Squarepoint Ops LLC10,605$383.0K0.00%+3,555+50.4%Added
Public Employees Retirement Association of Colorado10,633$384.0K0.00%00.0%Unchanged
Supplemental Annuity Collective Trust of NJ11,000$397.0K0.17%00.0%Unchanged
Oppenheimer & Co Inc11,113$401.0K0.01%+11,113New
Legal & General Group Plc11,578$418.0K0.00%+305+2.7%Added
Group One Trading, L.P.11,573$418.0K0.01%+2,813+32.1%Added
Boothbay Fund Management, LLC11,825$427.0K0.01%−14,481−55.0%Reduced
Victory Capital Management Inc12,228$441.0K0.00%−910−6.9%Reduced
Arizona State Retirement System12,427$449.0K0.00%+1,930+18.4%Added
Virginia Retirement Systems Et Al13,000$469.3K0.01%+13,000New
Guggenheim Capital LLC14,938$539.0K0.00%+561+3.9%Added
Teacher Retirement System of Texas14,954$540.0K0.00%+14,954New
Elmwood Wealth Management, Inc.14,994$541.0K0.27%00.0%Unchanged
HRT Financial LP15,927$574.0K0.01%−3,975−20.0%Reduced
New York State Common Retirement Fund16,000$578.0K0.00%00.0%Unchanged
Employees Retirement System of Texas16,001$578.0K0.01%00.0%Unchanged
Shell Asset Management Co17,400$628.0K0.02%−4,625−21.0%Reduced
DekaBank Deutsche Girozentrale20,000$721.0K0.00%+7,600+61.3%Added
Allianz Asset Management GmbH20,000$722.0K0.00%−68,630−77.4%Reduced
Velan Capital Investment Management LP20,000$722.0K0.85%00.0%Unchanged
Cubist Systematic Strategies, LLC20,211$730.0K0.01%−32,467−61.6%Reduced
Sanders Morris Harris LLC21,500$778.0K0.19%−3,000−12.2%Reduced
Natixis Advisors, L.P.21,603$780.0K0.00%+2,224+11.5%Added
SG Americas Securities, LLC21,832$788.0K0.01%−621−2.8%Reduced
Chartwell Investment Partners, LLC22,289$805.0K0.03%+781+3.6%Added
HighVista Strategies LLC22,572$815.0K0.47%+137+0.6%Added
CIBC World Markets Inc.23,300$841.0K0.00%−23,587−50.3%Reduced
Difesa Capital Management, LP24,500$884.0K0.65%+24,500New
NJ State Employees Deferred Compensation Plan25,000$903.0K0.15%00.0%Unchanged
International Biotechnology Trust PLC25,500$918.0K0.29%+24,726+3,194.6%Added
Bank of America Corp26,995$974.0K0.00%−9,660−26.4%Reduced
Bamco Inc27,500$993.0K0.00%+5,500+25.0%Added
Kynam Capital Management, LP28,792$1.04M0.22%−146,208−83.5%Reduced
Susquehanna Fundamental Investments, LLC33,181$1.20M0.02%+33,181New
Alps Advisors Inc33,959$1.23M0.01%+2,461+7.8%Added
Scotia Capital Inc.34,251$1.24M0.01%−3,223−8.6%Reduced
Qube Research & Technologies Ltd34,483$1.25M0.01%+34,483New
Erste Asset Management GmbH35,000$1.26M0.03%00.0%Unchanged
Advisory Research Inc36,438$1.32M0.13%+1,438+4.1%Added
UBS Asset Management Americas Inc38,404$1.39M0.00%+11,496+42.7%Added
California State Teachers Retirement System39,347$1.42M0.00%+316+0.8%Added
Ameriprise Financial Inc41,144$1.49M0.00%−10,032−19.6%Reduced
Jane Street Group, LLC41,912$1.51M0.00%+41,912New
Credit Suisse AG43,653$1.58M0.00%+10,469+31.5%Added
Fred Alger Management, LLC45,143$1.63M0.01%+45,143New
Bridger Management, LLC45,235$1.63M0.49%−32,165−41.6%Reduced
Algert Global LLC45,246$1.63M0.10%+18,842+71.4%Added
Twinbeech Capital LP48,750$1.76M0.05%+37,727+342.3%Added
Nuveen Asset Management, LLC50,360$1.82M0.00%+6,049+13.7%Added
Northern Trust Corp50,891$1.84M0.00%+2,895+6.0%Added
Jump Financial, LLC53,300$1.92M0.07%+53,300New
UBS Oconnor LLC54,208$1.96M0.02%−42,000−43.7%Reduced
Two Sigma Investments, LP55,974$2.02M0.01%+55,974New
Knott David M Jr59,500$2.15M1.01%00.0%Unchanged
Tekla Capital Management LLC61,733$2.23M0.09%+32,023+107.8%Added
Geode Capital Management, LLC61,823$2.23M0.00%+16,307+35.8%Added
State of New Jersey Common Pension Fund D64,454$2.33M0.01%+64,454New
LMR Partners LLP65,698$2.37M0.06%−34,302−34.3%Reduced
Voya Investment Management LLC67,140$2.42M0.00%+67,140New
Walleye Capital LLC87,971$3.18M0.07%−73,956−45.7%Reduced
Two Sigma Advisers, LP91,000$3.29M0.01%+38,700+74.0%Added
Soleus Capital Management, L.P.96,800$3.49M0.47%+21,800+29.1%Added
Russell Investments Group, Ltd.99,074$3.58M0.01%−8,825−8.2%Reduced
Moore Capital Management, LP102,977$3.72M0.10%−69,094−40.2%Reduced
Schonfeld Strategic Advisors LLC108,284$3.91M0.03%−19,825−15.5%Reduced