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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2024

Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
213
−6 vs. Q1 2024
Shares held
74.2M
+766.8K (+1.0%) vs. Q1 2024
Total value
$2.89B
−$268.1M (−8.5%) vs. Q1 2024
New holders
21
78 more added
Sold out
27
71 more reduced

1 institution that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 213 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ2 2024: $2.89B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2024.

Institutions holding XENE in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC6,768,173$263.9M0.02%+166,343+2.5%Added
Avoro Capital Advisors LLC5,666,666$220.9M2.94%00.0%Unchanged
Driehaus Capital Management LLC4,419,472$172.3M1.67%+97,732+2.3%Added
Wellington Management Group LLP3,828,221$149.3M0.03%−93,837−2.4%Reduced
Commodore Capital LP2,754,266$107.4M7.33%+586,473+27.1%Added
Capital World Investors2,681,537$104.6M0.02%00.0%Unchanged
Braidwell LP2,560,573$99.8M3.13%+1,252,562+95.8%Added
Polar Capital Holdings Plc2,536,058$98.9M0.58%−76,050−2.9%Reduced
Capital International Investors2,475,859$96.5M0.02%00.0%Unchanged
BlackRock Inc.2,095,894$81.7M0.00%−26,034−1.2%Reduced
Paradigm Biocapital Advisors LP2,043,280$79.7M3.05%−441,594−17.8%Reduced
Adage Capital Partners GP, L.L.C.1,839,555$71.7M0.13%+167,638+10.0%Added
Alliancebernstein L.P.1,483,166$57.8M0.02%+14,720+1.0%Added
Pictet Asset Management Holding SA1,479,491$57.7M0.07%−35,935−2.4%Reduced
T. Rowe Price Investment Management, Inc.1,439,903$56.1M0.04%+13,564+1.0%Added
Marshall Wace, LLP1,384,674$54.0M0.08%−65,668−4.5%Reduced
First Light Asset Management, LLC1,306,260$50.9M4.46%−13,912−1.1%Reduced
Rock Springs Capital Management LP1,272,877$49.6M1.50%+17,300+1.4%Added
Janus Henderson Group PLC1,045,257$40.8M0.02%+103,688+11.0%Added
Affinity Asset Advisors, LLC994,227$38.8M6.11%+156,840+18.7%Added
Baker Bros. Advisors LP993,679$38.7M0.50%00.0%Unchanged
Invesco Ltd.866,785$33.8M0.01%−182,741−17.4%Reduced
OrbiMed Advisors LLC862,362$33.6M0.72%+312,362+56.8%Added
Citadel Advisors LLC768,726$30.0M0.03%−518,349−40.3%Reduced
TimesSquare Capital Management, LLC754,493$29.4M0.46%+17,320+2.3%Added
Avidity Partners Management LP754,000$29.4M1.25%+44,000+6.2%Added
Federated Hermes, Inc.734,555$28.6M0.07%−3450.0%Reduced
Loomis Sayles & Co L P660,258$25.7M0.04%−26,252−3.8%Reduced
Westfield Capital Management Co LP643,546$25.1M0.12%+296,195+85.3%Added
Samlyn Capital, LLC639,685$24.9M0.43%+243,489+61.5%Added
Boxer Capital, LLC600,000$23.4M1.23%00.0%Unchanged
Perceptive Advisors LLC583,256$22.7M0.55%−308,952−34.6%Reduced
Fiera Capital Corp582,879$22.7M0.07%+6,337+1.1%Added
Franklin Resources Inc578,865$22.6M0.01%+36,576+6.7%Added
Jennison Associates LLC570,272$22.2M0.01%+6,320+1.1%Added
Vestal Point Capital, LP525,000$20.5M1.53%+125,000+31.3%Added
Candriam Luxembourg S.C.A.521,836$20.3M0.12%−39,048−7.0%Reduced
Point72 Asset Management, L.P.482,022$18.8M0.06%+206,163+74.7%Added
Dimensional Fund Advisors LP436,460$17.0M0.00%+26,253+6.4%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.421,121$16.4M0.04%+4,385+1.1%Added
Artal Group S.A.381,554$14.9M0.38%+128,167+50.6%Added
Logos Global Management LP375,000$14.6M1.68%+375,000New
Goldman Sachs Group Inc364,173$14.2M0.00%+64,399+21.5%Added
Altium Capital Management LP360,600$14.1M5.81%+12,600+3.6%Added
ExodusPoint Capital Management, LP357,178$13.9M0.15%+203,140+131.9%Added
Vanguard Group Inc341,152$13.3M0.00%+5,517+1.6%Added
First Turn Management, LLC339,876$13.3M2.16%−340,513−50.0%Reduced
Alyeska Investment Group, L.P.291,868$11.4M0.07%+53,025+22.2%Added
DAFNA Capital Management LLC273,739$10.7M2.55%00.0%Unchanged
Boone Capital Management LLC250,460$9.77M2.55%−40,943−14.1%Reduced
State Street Corp246,812$9.62M0.00%+4,172+1.7%Added
Morgan Stanley238,772$9.31M0.00%−147,427−38.2%Reduced
Balyasny Asset Management LLC233,335$9.10M0.02%+32,061+15.9%Added
Granahan Investment Management Inc226,166$8.82M0.35%−17,914−7.3%Reduced
Standard Life Aberdeen plc212,502$8.29M0.02%+180,466+563.3%Added
Parkman Healthcare Partners LLC209,290$8.16M1.11%−14,652−6.5%Reduced
Two Sigma Advisers, LP208,900$8.15M0.02%−20,300−8.9%Reduced
Two Sigma Investments, LP195,129$7.61M0.02%−79,497−28.9%Reduced
Lord, Abbett & Co. LLC190,033$7.41M0.02%−705,163−78.8%Reduced
AXA S.A.188,038$7.33M0.02%+166+0.1%Added
Algert Global LLC183,205$7.14M0.24%−810−0.4%Reduced
DnB Asset Management AS175,733$6.85M0.03%+49,483+39.2%Added
Millennium Management LLC175,584$6.85M0.01%+91,923+109.9%Added
Laurion Capital Management LP171,195$6.67M0.22%−67,931−28.4%Reduced
Ally Bridge Group (NY) LLC169,369$6.60M3.93%−140,000−45.3%Reduced
Ensign Peak Advisors, Inc163,064$6.36M0.01%00.0%Unchanged
Russell Investments Group, Ltd.162,850$6.35M0.01%−15,249−8.6%Reduced
UBS Asset Management Americas Inc162,466$6.33M0.00%+84,982+109.7%Added
D. E. Shaw & Co., Inc.161,722$6.31M0.01%−36,804−18.5%Reduced
New York State Common Retirement Fund150,840$5.88M0.01%−41,912−21.7%Reduced
PFM Health Sciences, LP150,554$5.87M0.32%00.0%Unchanged
Bridger Management, LLC146,800$5.72M2.95%00.0%Unchanged
Bank of America Corp142,332$5.55M0.00%−14,772−9.4%Reduced
Swiss National Bank126,100$4.92M0.00%+2,300+1.9%Added
Atika Capital Management LLC124,000$4.83M0.56%+2,000+1.6%Added
Ikarian Capital, LLC107,187$4.18M1.30%00.0%Unchanged
Nan Fung Group Holdings Ltd106,680$4.16M4.44%00.0%Unchanged
Tri Locum Partners LP101,959$3.98M1.01%−105,506−50.9%Reduced
Bamco Inc100,100$3.90M0.01%00.0%Unchanged
Renaissance Technologies LLC92,900$3.62M0.01%+36,500+64.7%Added
Schroder Investment Management Group91,500$3.57M0.00%00.0%Unchanged
State of Wisconsin Investment Board89,800$3.50M0.01%−1,985−2.2%Reduced
Twinbeech Capital LP88,711$3.46M0.07%−9,331−9.5%Reduced
Assenagon Asset Management S.A.73,602$2.87M0.01%−113,004−60.6%Reduced
HighVista Strategies LLC72,715$2.84M1.04%00.0%Unchanged
JPMorgan Chase & Co71,654$2.79M0.00%+35,033+95.7%Added
Jefferies Financial Group Inc.69,000$2.69M0.05%+3,363+5.1%Added
Geode Capital Management, LLC68,929$2.69M0.00%+4,700+7.3%Added
Wells Fargo & Company59,067$2.30M0.00%−2,390−3.9%Reduced
Alps Advisors Inc58,853$2.29M0.02%+5,653+10.6%Added
California State Teachers Retirement System58,140$2.27M0.00%+1,663+2.9%Added
Legal & General Group Plc55,120$2.15M0.00%+110+0.2%Added
Moore Capital Management, LP55,000$2.14M0.05%00.0%Unchanged
Deutsche Bank AG53,711$2.09M0.00%+15,000+38.7%Added
Prudential Financial Inc52,000$2.03M0.00%−7,000−11.9%Reduced
Bank of New York Mellon Corp51,254$2.00M0.00%−15,656−23.4%Reduced
Envestnet Asset Management Inc48,946$1.91M0.00%+769+1.6%Added
LMR Partners LLP48,668$1.90M0.04%00.0%Unchanged
State of New Jersey Common Pension Fund D48,573$1.89M0.01%−8,177−14.4%Reduced
Jump Financial, LLC48,166$1.88M0.04%+2,087+4.5%Added