Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Xenon Pharmaceuticals Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 159
- +5 vs. Q3 2022
- Shares held
- 60.4M
- +2.51M (+4.3%) vs. Q3 2022
- Total value
- $2.38B
- +$291.8M (+14.0%) vs. Q3 2022
- New holders
- 22
- 60 more added
- Sold out
- 17
- 46 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 4,900,000 | $193.2M | 2.89% | 00.0% | Unchanged |
| FMR LLC | 4,690,829 | $185.0M | 0.02% | +21,070+0.5% | Added |
| Driehaus Capital Management LLC | 4,681,797 | $184.6M | 2.75% | +177,777+3.9% | Added |
| Polar Capital Holdings Plc | 3,045,874 | $120.1M | 0.96% | +383,152+14.4% | Added |
| Marshall Wace, LLP | 2,366,178 | $93.3M | 0.24% | −444,917−15.8% | Reduced |
| Redmile Group, LLC | 2,360,414 | $93.1M | 3.81% | −10,200−0.4% | Reduced |
| Capital World Investors | 2,274,974 | $89.7M | 0.02% | 00.0% | Unchanged |
| Lord, Abbett & Co. LLC | 2,124,009 | $83.7M | 0.30% | +210,148+11.0% | Added |
| Pictet Asset Management SA | 2,119,619 | $83.6M | 0.12% | −167,746−7.3% | Reduced |
| Capital International Investors | 2,099,579 | $82.8M | 0.02% | +457,071+27.8% | Added |
| Perceptive Advisors LLC | 1,921,273 | $75.8M | 2.18% | −201,262−9.5% | Reduced |
| Commodore Capital LP | 1,659,111 | $65.4M | 9.86% | +64,179+4.0% | Added |
| Braidwell LP | 1,548,110 | $61.0M | 2.05% | +1,548,110 | New |
| BVF Inc | 1,271,243 | $50.1M | 2.12% | +370,148+41.1% | Added |
| Samlyn Capital, LLC | 1,193,814 | $47.1M | 0.92% | −95,419−7.4% | Reduced |
| Holocene Advisors, LP | 1,191,638 | $47.0M | 0.29% | −637,514−34.9% | Reduced |
| Point72 Asset Management, L.P. | 1,178,324 | $46.5M | 0.18% | −461,748−28.2% | Reduced |
| Rock Springs Capital Management LP | 1,175,672 | $46.4M | 1.12% | +19,711+1.7% | Added |
| Citadel Advisors LLC | 1,164,407 | $45.9M | 0.05% | +22,405+2.0% | Added |
| OrbiMed Advisors LLC | 1,149,100 | $45.3M | 0.87% | +11,800+1.0% | Added |
| BlackRock Inc. | 925,623 | $36.5M | 0.00% | −116,906−11.2% | Reduced |
| Logos Global Management LP | 900,000 | $35.5M | 4.16% | +400,000+80.0% | Added |
| Great Point Partners LLC | 850,000 | $33.5M | 6.93% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 751,639 | $29.6M | 0.18% | 00.0% | Unchanged |
| Candriam Luxembourg S.C.A. | 735,884 | $29.0M | 0.20% | −25,000−3.3% | Reduced |
| Adage Capital Partners GP, L.L.C. | 725,000 | $28.6M | 0.07% | +50,000+7.4% | Added |
| Loomis Sayles & Co L P | 677,165 | $26.7M | 0.05% | +677,165 | New |
| Eventide Asset Management, LLC | 641,200 | $25.3M | 0.50% | 00.0% | Unchanged |
| Boxer Capital, LLC | 600,000 | $23.7M | 1.27% | 00.0% | Unchanged |
| Millennium Management LLC | 594,541 | $23.4M | 0.03% | +34,192+6.1% | Added |
| TimesSquare Capital Management, LLC | 482,180 | $19.0M | 0.27% | +482,180 | New |
| Bank of New York Mellon Corp | 388,360 | $15.3M | 0.00% | −49,285−11.3% | Reduced |
| D. E. Shaw & Co., Inc. | 360,421 | $14.2M | 0.02% | −49,142−12.0% | Reduced |
| Granahan Investment Management Inc | 324,250 | $12.8M | 0.39% | +24,395+8.1% | Added |
| DAFNA Capital Management LLC | 316,092 | $12.5M | 3.51% | −59,131−15.8% | Reduced |
| Dimensional Fund Advisors LP | 314,673 | $12.4M | 0.00% | −27,358−8.0% | Reduced |
| Woodline Partners LP | 298,440 | $11.8M | 0.16% | −105,919−26.2% | Reduced |
| Janus Henderson Group PLC | 291,786 | $11.5M | 0.01% | +57,952+24.8% | Added |
| Goldman Sachs Group Inc | 283,541 | $11.2M | 0.00% | −181,724−39.1% | Reduced |
| Eversept Partners, LP | 275,704 | $10.9M | 1.03% | +16,092+6.2% | Added |
| Silverarc Capital Management, LLC | 253,655 | $10.0M | 3.44% | +7,663+3.1% | Added |
| Nicholas Investment Partners, LP | 252,302 | $9.95M | 0.87% | +252,302 | New |
| Parkman Healthcare Partners LLC | 235,491 | $9.29M | 2.47% | +12,894+5.8% | Added |
| State of Wisconsin Investment Board | 217,620 | $8.58M | 0.03% | +146+0.1% | Added |
| State Street Corp | 197,436 | $7.78M | 0.00% | +27,065+15.9% | Added |
| Vanguard Group Inc | 192,076 | $7.57M | 0.00% | +6,884+3.7% | Added |
| AXA S.A. | 190,794 | $7.52M | 0.03% | −1,042−0.5% | Reduced |
| Schonfeld Strategic Advisors LLC | 168,413 | $6.64M | 0.06% | +60,129+55.5% | Added |
| Ensign Peak Advisors, Inc | 164,380 | $6.48M | 0.01% | +50,900+44.9% | Added |
| Balyasny Asset Management LLC | 162,828 | $6.42M | 0.02% | +15,473+10.5% | Added |
| Ikarian Capital, LLC | 160,486 | $6.33M | 2.63% | 00.0% | Unchanged |
| Putnam Investments LLC | 152,660 | $6.02M | 0.01% | +23,376+18.1% | Added |
| EAM Global Investors LLC | 146,387 | $5.77M | 1.49% | −8,098−5.2% | Reduced |
| Moore Capital Management, LP | 129,417 | $5.10M | 0.14% | +26,440+25.7% | Added |
| Nan Fung Group Holdings Ltd | 114,380 | $4.51M | 3.11% | 00.0% | Unchanged |
| Swiss National Bank | 112,700 | $4.44M | 0.00% | +4,300+4.0% | Added |
| Twinbeech Capital LP | 101,717 | $4.01M | 0.08% | +52,967+108.7% | Added |
| DnB Asset Management AS | 94,551 | $3.73M | 0.03% | +94,551 | New |
| Tri Locum Partners LP | 93,364 | $3.68M | 1.63% | −40,967−30.5% | Reduced |
| Bank of America Corp | 88,748 | $3.50M | 0.00% | +61,753+228.8% | Added |
| Morgan Stanley | 88,134 | $3.48M | 0.00% | −70,318−44.4% | Reduced |
| Walleye Capital LLC | 86,517 | $3.41M | 0.07% | −1,454−1.7% | Reduced |
| Russell Investments Group, Ltd. | 84,330 | $3.33M | 0.01% | −14,744−14.9% | Reduced |
| Tekla Capital Management LLC | 83,714 | $3.30M | 0.12% | +21,981+35.6% | Added |
| Castleark Management LLC | 77,740 | $3.07M | 0.16% | +77,740 | New |
| Qube Research & Technologies Ltd | 75,759 | $2.99M | 0.02% | +41,276+119.7% | Added |
| Voya Investment Management LLC | 67,140 | $2.65M | 0.00% | 00.0% | Unchanged |
| State of New Jersey Common Pension Fund D | 64,454 | $2.54M | 0.01% | 00.0% | Unchanged |
| Northern Trust Corp | 60,217 | $2.37M | 0.00% | +9,326+18.3% | Added |
| Knott David M Jr | 59,500 | $2.35M | 1.01% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 56,835 | $2.24M | 0.00% | −85,891−60.2% | Reduced |
| Geode Capital Management, LLC | 55,285 | $2.18M | 0.00% | −6,538−10.6% | Reduced |
| Credit Suisse AG | 54,789 | $2.16M | 0.00% | +11,136+25.5% | Added |
| Nuveen Asset Management, LLC | 51,280 | $2.02M | 0.00% | +920+1.8% | Added |
| LMR Partners LLP | 50,000 | $1.97M | 0.05% | −15,698−23.9% | Reduced |
| Affinity Asset Advisors, LLC | 50,000 | $1.97M | 0.90% | +50,000 | New |
| Bamco Inc | 47,400 | $1.87M | 0.01% | +19,900+72.4% | Added |
| Cheyne Capital Management (UK) LLP | 42,500 | $1.68M | 2.96% | +42,500 | New |
| Alps Advisors Inc | 42,371 | $1.67M | 0.01% | +8,412+24.8% | Added |
| California State Teachers Retirement System | 40,635 | $1.60M | 0.00% | +1,288+3.3% | Added |
| UBS Asset Management Americas Inc | 38,938 | $1.54M | 0.00% | +534+1.4% | Added |
| Soleus Capital Management, L.P. | 38,000 | $1.50M | 0.21% | −58,800−60.7% | Reduced |
| Algert Global LLC | 36,416 | $1.44M | 0.08% | −8,830−19.5% | Reduced |
| SG Americas Securities, LLC | 35,465 | $1.40M | 0.02% | +13,633+62.4% | Added |
| Erste Asset Management GmbH | 35,000 | $1.37M | 0.03% | 00.0% | Unchanged |
| TLS Advisors LLC | 33,756 | $1.33M | 6.56% | +33,756 | New |
| Advisory Research Inc | 32,731 | $1.29M | 0.12% | −3,707−10.2% | Reduced |
| Mirabella Financial Services LLP | 31,459 | $1.24M | 0.11% | +31,459 | New |
| Kynam Capital Management, LP | 28,887 | $1.14M | 0.17% | +95+0.3% | Added |
| Susquehanna Fundamental Investments, LLC | 28,663 | $1.13M | 0.02% | −4,518−13.6% | Reduced |
| Scotia Capital Inc. | 26,859 | $1.06M | 0.01% | −7,392−21.6% | Reduced |
| International Biotechnology Trust PLC | 25,500 | $1.00M | 0.31% | 00.0% | Unchanged |
| HighVista Strategies LLC | 25,340 | $999.2K | 0.59% | +2,768+12.3% | Added |
| NJ State Employees Deferred Compensation Plan | 25,000 | $985.8K | 0.16% | 00.0% | Unchanged |
| Chartwell Investment Partners, LLC | 23,630 | $932.0K | 0.04% | +1,341+6.0% | Added |
| Two Sigma Advisers, LP | 22,700 | $895.1K | 0.00% | −68,300−75.1% | Reduced |
| Ameriprise Financial Inc | 22,626 | $891.0K | 0.00% | −18,518−45.0% | Reduced |
| CIBC World Markets Inc. | 22,550 | $889.0K | 0.00% | −750−3.2% | Reduced |
| Sanders Morris Harris LLC | 21,500 | $847.7K | 0.32% | 00.0% | Unchanged |
| Natixis Advisors, L.P. | 21,492 | $847.0K | 0.00% | −111−0.5% | Reduced |