Xenon Pharmaceuticals Inc.

XENE

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0001582313

SEC filings (opens in a new tab)

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 2 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

Q4 2022 vs. Q3 2022

How the institutions holding Xenon Pharmaceuticals Inc. changed between Q3 2022 and Q4 2022.

All holders in Q4 2022 All holders in Q3 2022

13F holders of XENE: Q3 2022 compared with Q4 2022
Measure	Q3 2022	Q4 2022	Change
Holders	154	159	+5
Shares	57.9M	60.4M	+2.51M (+4.3%)
Value	$2.09B	$2.38B	+$291.8M (+14.0%)

New holders (22)

Institutions that held Xenon Pharmaceuticals Inc. at the end of Q4 2022 but not at the end of Q3 2022.

Institutions new to XENE in Q4 2022
Institution	Shares	Value	% of portfolio
Braidwell LP	1,548,110	$61.0M	2.05%
Loomis Sayles & Co L P	677,165	$26.7M	0.05%
TimesSquare Capital Management, LLC	482,180	$19.0M	0.27%
Nicholas Investment Partners, LP	252,302	$9.95M	0.87%
DnB Asset Management AS	94,551	$3.73M	0.03%
Castleark Management LLC	77,740	$3.07M	0.16%
Affinity Asset Advisors, LLC	50,000	$1.97M	0.90%
Cheyne Capital Management (UK) LLP	42,500	$1.68M	2.96%
TLS Advisors LLC	33,756	$1.33M	6.56%
Mirabella Financial Services LLP	31,459	$1.24M	0.11%
Jefferies Financial Group Inc.	19,500	$768.9K	0.01%
PFM Health Sciences, LP	17,488	$689.6K	0.03%
Gsa Capital Partners LLP	13,763	$543.0K	0.07%
Ergoteles LLC	13,516	$532.9K	0.02%
Prelude Capital Management, LLC	12,769	$503.5K	0.03%
Connor, Clark & Lunn Investment Management Ltd.	5,799	$228.7K	0.00%
Virtu Financial LLC	5,604	$221.0K	0.03%
ProShare Advisors LLC	5,172	$203.9K	0.00%
Northwestern Mutual Wealth Management Co	5,000	$197.2K	0.00%
Deutsche Bank AG	2,495	$98.4K	0.00%
Belpointe Asset Management LLC	70	$2.76K	0.00%
Ronald Blue Trust, Inc.	29	$1.00K	0.00%

Sold out (17)

Institutions that held Xenon Pharmaceuticals Inc. at the end of Q3 2022 and filed for Q4 2022 without it.

Institutions that sold out of XENE in Q4 2022
Institution	Shares, Q3 2022	Value, Q3 2022
Acuta Capital Partners, LLC	272,500	$9.84M
Two Sigma Investments, LP	55,974	$2.02M
UBS Oconnor LLC	54,208	$1.96M
Bridger Management, LLC	45,235	$1.63M
Fred Alger Management, LLC	45,143	$1.63M
Difesa Capital Management, LP	24,500	$884.0K
HRT Financial LP	15,927	$574.0K
Victory Capital Management Inc	12,228	$441.0K
Oppenheimer & Co Inc	11,113	$401.0K
Squarepoint Ops LLC	10,605	$383.0K
Dynamic Technology Lab Private Ltd	9,990	$361.0K
Occudo Quantitative Strategies LP	7,263	$262.0K
Walleye Trading LLC	5,603	$202.0K
Amundi	3,581	$133.0K
Quantbot Technologies LP	1,300	$46.0K
Macquarie Group Ltd	132	$24.0K
Simplex Trading, LLC	432	$15.0K