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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2023

Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
175
+13 vs. Q1 2023
Shares held
61.3M
+174.4K (+0.3%) vs. Q1 2023
Total value
$2.36B
+$174.7M (+8.0%) vs. Q1 2023
New holders
33
57 more added
Sold out
20
56 more reduced

1 institution that held it in Q1 2023 haven't filed for Q2 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 175 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ2 2023: $2.36B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2023.

Institutions holding XENE in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Qube Research & Technologies Ltd29,967$1.15M0.00%+15,514+107.3%Added
International Biotechnology Trust PLC25,500$981.8K0.30%00.0%Unchanged
NJ State Employees Deferred Compensation Plan25,000$962.5K0.14%00.0%Unchanged
Tri Locum Partners LP24,221$932.5K0.35%−197,509−89.1%Reduced
Royal Bank of Canada24,201$932.0K0.00%+11,717+93.9%Added
Bellevue Group AG23,900$920.1K0.01%+23,900New
Knott David M Jr23,866$919.0K0.39%−16,134−40.3%Reduced
Chartwell Investment Partners, LLC23,301$897.1K0.03%+1,133+5.1%Added
Natixis Advisors, L.P.22,020$848.0K0.00%+279+1.3%Added
Sanders Morris Harris LLC21,500$822.4K0.18%+21,500New
Stifel Financial Corp20,081$773.2K0.00%+9,777+94.9%Added
DekaBank Deutsche Girozentrale20,000$772.0K0.00%00.0%Unchanged
Two Sigma Investments, LP18,633$717.4K0.00%+7,179+62.7%Added
HRT Financial LP17,946$690.0K0.01%+17,946New
Calamos Advisors LLC17,637$679.0K0.00%+17,637New
HighVista Strategies LLC17,575$676.6K0.31%−7,765−30.6%Reduced
Envestnet Asset Management Inc16,522$636.1K0.00%+16,522New
Brinker Capital Investments, LLC15,806$608.5K0.01%+15,806New
Orion Portfolio Solutions, LLC15,806$608.5K0.01%+15,806New
Prelude Capital Management, LLC15,472$595.7K0.05%−6,540−29.7%Reduced
Shell Asset Management Co14,515$559.0K0.02%−83−0.6%Reduced
SEI Investments Co14,427$555.4K0.00%+14,427New
Arizona State Retirement System14,165$545.4K0.00%+574+4.2%Added
Handelsbanken Fonder AB14,100$543.0K0.00%00.0%Unchanged
Teacher Retirement System of Texas13,672$526.0K0.00%−779−5.4%Reduced
Legato Capital Management LLC12,310$473.9K0.06%+12,310New
Supplemental Annuity Collective Trust of NJ11,000$423.5K0.15%00.0%Unchanged
Public Employees Retirement Association of Colorado10,633$409.0K0.00%00.0%Unchanged
Guggenheim Capital LLC10,374$399.4K0.00%−8,848−46.0%Reduced
Elmwood Wealth Management, Inc.10,069$387.7K0.18%−4,925−32.8%Reduced
Birchview Capital, LP10,000$385.0K0.29%00.0%Unchanged
Boothbay Fund Management, LLC9,983$384.3K0.01%−1,842−15.6%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)9,193$353.9K0.00%−114−1.2%Reduced
Barclays PLC9,179$353.4K0.00%+9,079+9,079.0%Added
Jefferies Financial Group Inc.8,769$337.6K0.01%+8,769New
Jane Street Group, LLC8,717$335.6K0.00%+3,051+53.8%Added
Susquehanna International Group, LLP8,131$313.0K0.00%−7,438−47.8%Reduced
Advisors Asset Management, Inc.8,092$311.5K0.01%−300−3.6%Reduced
Trexquant Investment LP7,446$286.7K0.01%+7,446New
Natixis7,000$269.5K0.00%+7,000New
Virtu Financial LLC6,682$257.0K0.02%+6,682New
Victory Capital Management Inc6,500$250.3K0.00%−21,690−76.9%Reduced
Oppenheimer Asset Management Inc.6,230$239.9K0.00%+6,230New
Connacht Asset Management LP6,165$237.4K0.81%−226−3.5%Reduced
Snowden Capital Advisors LLC5,996$230.8K0.01%+5,996New
Assetmark, Inc5,845$225.0K0.00%+5,845New
Walleye Trading LLC5,669$218.3K0.01%−2,342−29.2%Reduced
Tower Research Capital LLC (TRC)5,524$212.7K0.01%+5,013+981.0%Added
Northwestern Mutual Wealth Management Co5,000$192.5K0.00%00.0%Unchanged
UBS Group AG4,879$187.8K0.00%+265+5.7%Added
Citigroup Inc4,154$159.9K0.00%−3,663−46.9%Reduced
Exchange Traded Concepts, LLC3,247$125.0K0.00%+3,247New
Deutsche Bank AG3,034$116.8K0.00%+539+21.6%Added
Advisor Group Holdings, Inc.2,691$103.6K0.00%+2,009+294.6%Added
Virtus ETF Advisers LLC2,552$98.3K0.06%−58−2.2%Reduced
Proequities, Inc.2,000$77.0K0.01%00.0%Unchanged
Great West Life Assurance Co1,693$66.0K0.00%−699−29.2%Reduced
BNP Paribas Arbitrage, SA1,441$55.5K0.00%+413+40.2%Added
China Universal Asset Management Co., Ltd.833$32.1K0.01%−15−1.8%Reduced
Parallel Advisors, LLC776$29.9K0.00%+776New
First Horizon Advisors, Inc.570$21.9K0.00%+370+185.0%Added
Harbor Capital Advisors, Inc.547$21.1K0.00%+547New
Leonteq Securities AG530$20.4K0.00%00.0%Unchanged
IFP Advisors, Inc2,178$12.4K0.00%+1,178+117.8%Added
Daiwa Securities Group Inc.252$10.0K0.00%00.0%Unchanged
US Bancorp259$9.97K0.00%+259New
Hexagon Capital Partners LLC82$3.16K0.00%00.0%Unchanged
Whittier Trust Co of Nevada Inc38$1.46K0.00%+38New
Park Place Capital Corp22$8470.00%+22New
Allianz Asset Management GmbH13,200$5080.00%−6,800−34.0%Reduced
Signaturefd, LLC13$5010.00%−20−60.6%Reduced
SJS Investment Consulting Inc.2$770.00%+2New
AdvisorNet Financial, Inc1$390.00%+1New
JFS Wealth Advisors, LLC1$390.00%+1New
Disciplined Investments, LLC1$390.00%+1New
Norges Bank0$00.00%−365,830−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−302,980−100.0%Sold out
Nomura Holdings Inc0$00.00%−221,095−100.0%Sold out
Weiss Multi-Strategy Advisers LLC0$00.00%−54,140−100.0%Sold out
Moore Capital Management, LP0$00.00%−34,417−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−29,908−100.0%Sold out
Kynam Capital Management, LP0$00.00%−28,696−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−18,562−100.0%Sold out
Oppenheimer & Co Inc0$00.00%−12,615−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−10,900−100.0%Sold out
Virginia Retirement Systems Et Al0$00.00%−10,300−100.0%Sold out
American Century Companies Inc0$00.00%−9,474−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−8,400−100.0%Sold out
Kapitalo Investimentos Ltda0$00.00%−3,612−100.0%Sold out
Values First Advisors, Inc.0$00.00%−3,498−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−2,455−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−2,000−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−1,955−100.0%Sold out
Belpointe Asset Management LLC0$00.00%−70−100.0%Sold out
Mirabella Financial Services LLP0$00.00%−11,802−100.0%Sold out
Householder Group Estate & Retirement Specialist, LLC––––Not filed