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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2022

Institutional positions in Xenon Pharmaceuticals Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
132
+2 vs. Q4 2021
Shares held
49.2M
+1.48M (+3.1%) vs. Q4 2021
Total value
$1.50B
+$10.8M (+0.7%) vs. Q4 2021
New holders
18
49 more added
Sold out
16
40 more reduced

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 132 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ1 2022: $1.50B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q4 2021.

Institutions holding XENE in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
State of Wyoming49$1.00K0.00%+9+22.5%Added
Patriot Financial Group Insurance Agency, LLC35$1.00K0.00%+35New
Advisor Group Holdings, Inc.100$3.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.141$4.00K0.00%00.0%Unchanged
Barclays PLC191$6.00K0.00%+191New
Brown Brothers Harriman & Co294$9.00K0.00%00.0%Unchanged
Aquatic Capital Management LLC400$12.0K0.02%−5,000−92.6%Reduced
IFP Advisors, Inc2,000$12.0K0.00%+1,000+100.0%Added
Leonteq Securities AG530$16.2K0.00%00.0%Unchanged
Macquarie Group Ltd671$21.0K0.00%−2,843−80.9%Reduced
High Net Worth Advisory Group LLC1,000$31.0K0.01%00.0%Unchanged
UBS Group AG1,223$38.0K0.00%−554−31.2%Reduced
BNP Paribas Arbitrage, SA1,334$40.8K0.00%+1,254+1,567.5%Added
Tower Research Capital LLC (TRC)1,462$44.0K0.00%+816+126.3%Added
Great West Life Assurance Co1,857$60.0K0.00%00.0%Unchanged
Proequities, Inc.2,000$61.0K0.00%00.0%Unchanged
Group One Trading, L.P.4,607$141.0K0.00%+4,607New
Amundi4,326$148.0K0.00%−202−4.5%Reduced
Virtus ETF Advisers LLC6,078$186.0K0.08%−361−5.6%Reduced
Bank of America Corp6,279$192.0K0.00%−36,519−85.3%Reduced
JPMorgan Chase & Co6,371$194.0K0.00%+1,596+33.4%Added
Zurcher Kantonalbank (Zurich Cantonalbank)6,733$206.0K0.00%−2,832−29.6%Reduced
Connor, Clark & Lunn Investment Management Ltd.7,658$234.0K0.00%+7,658New
Ensign Peak Advisors, Inc8,520$260.0K0.00%−28,595−77.0%Reduced
Teacher Retirement System of Texas8,545$261.0K0.00%−28,483−76.9%Reduced
Janus Henderson Group PLC10,281$315.0K0.00%+10,281New
Legal & General Group Plc10,771$330.0K0.00%+258+2.5%Added
Stifel Financial Corp10,867$332.0K0.00%−617−5.4%Reduced
Supplemental Annuity Collective Trust of NJ11,000$336.0K0.11%00.0%Unchanged
Arizona State Retirement System11,156$341.0K0.00%+477+4.5%Added
Jupiter Asset Management Ltd11,453$350.0K0.00%+11,453New
New York State Common Retirement Fund11,500$352.0K0.00%+3,400+42.0%Added
Algert Global LLC12,074$369.0K0.02%+12,074New
DekaBank Deutsche Girozentrale12,400$373.0K0.00%+1,100+9.7%Added
Victory Capital Management Inc14,264$403.0K0.00%+6,719+89.1%Added
Graham Capital Management, L.P.13,191$403.0K0.02%+13,191New
Dynamic Technology Lab Private Ltd13,993$428.0K0.05%+13,993New
Guggenheim Capital LLC14,193$434.0K0.00%+509+3.7%Added
Elmwood Wealth Management, Inc.14,994$458.0K0.24%−3,086−17.1%Reduced
Pura Vida Investments, LLC15,002$459.0K0.06%−33,500−69.1%Reduced
Jane Street Group, LLC16,117$493.0K0.00%+16,117New
Handelsbanken Fonder AB17,600$538.0K0.00%−3,100−15.0%Reduced
Granite Point Capital Management, L.P.20,000$611.0K0.31%−5,000−20.0%Reduced
Susquehanna International Group, LLP20,191$617.0K0.00%+20,191New
Shell Asset Management Co22,031$673.0K0.02%−3,298−13.0%Reduced
Royal Bank of Canada24,313$743.0K0.00%00.0%Unchanged
Boothbay Fund Management, LLC24,326$744.0K0.02%+5,950+32.4%Added
NJ State Employees Deferred Compensation Plan25,000$764.0K0.10%00.0%Unchanged
Parametric Portfolio Associates LLC26,338$805.0K0.00%+26,338New
Twinbeech Capital LP27,468$840.0K0.04%+20,590+299.4%Added
HighVista Strategies LLC27,992$856.0K0.54%−34,914−55.5%Reduced
Geode Capital Management, LLC28,198$862.0K0.00%00.0%Unchanged
Moore Capital Management, LP28,679$877.0K0.03%+28,679New
UBS Asset Management Americas Inc28,836$881.5K0.00%+774+2.8%Added
Jump Financial, LLC30,101$920.0K0.04%−1,199−3.8%Reduced
Credit Suisse AG30,150$922.0K0.00%+5,246+21.1%Added
Engineers Gate Manager LP32,805$1.00M0.04%+23,722+261.2%Added
State of Wisconsin Investment Board34,200$1.04M0.00%+34,200New
Scotia Capital Inc.34,216$1.05M0.01%+520+1.5%Added
Erste Asset Management GmbH35,000$1.05M0.02%00.0%Unchanged
California State Teachers Retirement System35,087$1.07M0.00%+1,579+4.7%Added
CIBC World Markets Inc.41,337$1.26M0.00%−8,297−16.7%Reduced
Altshuler Shaham Ltd42,000$1.28M0.01%−11,600−21.6%Reduced
Bamco Inc42,000$1.28M0.00%00.0%Unchanged
Cinctive Capital Management LP42,303$1.29M0.06%00.0%Unchanged
Northern Trust Corp44,776$1.37M0.00%−5,820−11.5%Reduced
Susquehanna Fundamental Investments, LLC45,647$1.40M0.03%+24,781+118.8%Added
Silverarc Capital Management, LLC101,081$1.43M0.78%+1,081+1.1%Added
Nuveen Asset Management, LLC49,797$1.57M0.00%+7,913+18.9%Added
Ameriprise Financial Inc57,932$1.77M0.00%−389−0.7%Reduced
Knott David M Jr66,500$2.03M0.70%−19,988−23.1%Reduced
Russell Investments Group, Ltd.73,919$2.26M0.00%+21,748+41.7%Added
Cubist Systematic Strategies, LLC74,039$2.26M0.02%+59,498+409.2%Added
Polar Asset Management Partners Inc.78,300$2.39M0.03%00.0%Unchanged
Affinity Asset Advisors, LLC80,000$2.45M0.97%−70,500−46.8%Reduced
Swiss National Bank97,500$2.98M0.00%+10,100+11.6%Added
Ghost Tree Capital, LLC100,000$3.06M1.51%00.0%Unchanged
Ci Investments Inc.100,705$3.08M0.01%+100,705New
Allianz Asset Management GmbH102,185$3.12M0.00%+32,280+46.2%Added
Schonfeld Strategic Advisors LLC102,374$3.13M0.03%+13,474+15.2%Added
Citigroup Inc102,475$3.13M0.00%+100,174+4,353.5%Added
Sio Capital Management, LLC105,756$3.23M1.30%+105,756New
Two Sigma Advisers, LP122,700$3.75M0.01%−3,900−3.1%Reduced
Millennium Management LLC136,326$4.17M0.01%+45,705+50.4%Added
Renaissance Technologies LLC150,777$4.61M0.01%−230,100−60.4%Reduced
Walleye Capital LLC154,308$4.72M0.14%+82,324+114.4%Added
Vanguard Group Inc163,468$5.00M0.00%+10,102+6.6%Added
State Street Corp171,987$5.26M0.00%+10,738+6.7%Added
Soleus Capital Management, L.P.189,797$5.80M0.89%−189,200−49.9%Reduced
AXA S.A.195,052$5.96M0.02%+40.0%Added
Nan Fung Group Holdings Ltd197,880$6.05M2.87%00.0%Unchanged
Invesco Ltd.198,701$6.07M0.00%−95,399−32.4%Reduced
Acuta Capital Partners, LLC225,000$6.88M3.27%00.0%Unchanged
Two Sigma Investments, LP232,650$7.11M0.02%−45,693−16.4%Reduced
Ikarian Capital, LLC239,441$7.32M2.23%+60,303+33.7%Added
Granahan Investment Management Inc262,705$8.03M0.20%+45,404+20.9%Added
Dimensional Fund Advisors LP293,729$8.98M0.00%+1,783+0.6%Added
Parkman Healthcare Partners LLC304,186$9.30M2.72%−56,316−15.6%Reduced
D. E. Shaw & Co., Inc.330,527$10.1M0.01%−144,613−30.4%Reduced
Alliancebernstein L.P.376,651$11.5M0.00%+82,553+28.1%Added