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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q4 2023

Institutional positions in Xenon Pharmaceuticals Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
204
+26 vs. Q3 2023
Shares held
72.1M
+10.8M (+17.6%) vs. Q3 2023
Total value
$3.32B
+$1.23B (+58.6%) vs. Q3 2023
New holders
46
85 more added
Sold out
20
52 more reduced

3 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 204 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ4 2023: $3.32B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q3 2023.

Institutions holding XENE in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
AdvisorNet Financial, Inc2$920.00%−1−33.3%Reduced
JFS Wealth Advisors, LLC2$930.00%−5−71.4%Reduced
DiNuzzo Private Wealth, Inc.2$930.00%+2New
Crewe Advisors LLC4$1850.00%+4New
SJS Investment Consulting Inc.5$2310.00%+2+66.7%Added
Principal Securities, Inc.16$7370.00%+16New
GAMMA Investing LLC22$9950.00%+22New
Headlands Technologies LLC23$1.06K0.00%−4−14.8%Reduced
CVA Family Office, LLC33$1.52K0.00%+33New
Whittier Trust Co of Nevada Inc38$1.75K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC46$2.12K0.00%+46New
GWM Advisors LLC64$2.95K0.00%+64New
Ronald Blue Trust, Inc.122$4.00K0.00%+122New
Signaturefd, LLC129$5.94K0.00%+125+3,125.0%Added
Householder Group Estate & Retirement Specialist, LLC215$9.00K0.00%−68−24.0%Reduced
Daiwa Securities Group Inc.252$12.0K0.00%00.0%Unchanged
Cambridge Trust Co300$13.8K0.00%+300New
Accent Capital Management, LLC400$18.4K0.01%+400New
First Horizon Advisors, Inc.570$26.3K0.00%00.0%Unchanged
US Bancorp933$43.0K0.00%+674+260.2%Added
LMR Partners LLP958$44.1K0.00%−24,042−96.2%Reduced
Quarry LP1,000$46.1K0.02%−3,500−77.8%Reduced
Tower Research Capital LLC (TRC)1,014$46.7K0.00%+817+414.7%Added
Parallel Advisors, LLC1,125$51.8K0.00%+381+51.2%Added
The PNC Financial Services Group, Inc.1,980$91.2K0.00%+1,980New
Proequities, Inc.2,000$92.1K0.01%00.0%Unchanged
IFP Advisors, Inc2,148$98.9K0.00%−30−1.4%Reduced
Virtus ETF Advisers LLC2,245$103.4K0.07%−79−3.4%Reduced
Deutsche Bank AG2,495$114.9K0.00%00.0%Unchanged
Lynwood Capital Management Inc.2,500$115.2K0.51%+2,500New
Advisor Group Holdings, Inc.2,665$122.7K0.00%−1,222−31.4%Reduced
Citigroup Inc3,004$138.4K0.00%+138+4.8%Added
BNP Paribas Arbitrage, SA4,390$202.2K0.00%+2,707+160.8%Added
Oppenheimer Asset Management Inc.4,428$204.0K0.00%−1,783−28.7%Reduced
ProShare Advisors LLC4,721$217.4K0.00%+4,721New
Weiss Multi-Strategy Advisers LLC5,000$230.0K0.01%+5,000New
Northwestern Mutual Wealth Management Co5,000$230.3K0.00%00.0%Unchanged
Walleye Capital LLC5,054$232.8K0.00%−120,974−96.0%Reduced
Vident Advisory, LLC5,292$243.7K0.01%+5,292New
Great West Life Assurance Co5,341$244.0K0.00%+848+18.9%Added
Snowden Capital Advisors LLC5,723$263.6K0.01%−142−2.4%Reduced
Fox Run Management, L.L.C.6,595$303.8K0.08%+6,595New
Natixis7,000$322.4K0.00%−3,000−30.0%Reduced
Axq Capital, LP7,006$322.7K0.09%+7,006New
American Century Companies Inc7,199$331.6K0.00%+7,199New
Nebula Research & Development LLC7,281$335.4K0.10%+7,281New
Omers Administration Corp7,700$354.7K0.00%+7,700New
Aigen Investment Management, LP8,043$370.5K0.07%+8,043New
SEI Investments Co8,179$376.7K0.00%−158−1.9%Reduced
Squarepoint Ops LLC8,253$380.1K0.00%+8,253New
Brinker Capital Investments, LLC8,217$393.4K0.00%−7,185−46.6%Reduced
Orion Portfolio Solutions, LLC8,217$393.4K0.00%−7,185−46.6%Reduced
China Universal Asset Management Co., Ltd.8,546$393.6K0.08%+6,895+417.6%Added
Capstone Investment Advisors, LLC8,861$408.1K0.01%+8,861New
Moody Aldrich Partners LLC9,123$420.2K0.08%00.0%Unchanged
Guggenheim Capital LLC9,529$438.9K0.00%−1,603−14.4%Reduced
Assetmark, Inc9,938$457.7K0.00%+2,835+39.9%Added
Birchview Capital, LP10,000$460.6K0.36%00.0%Unchanged
Ghisallo Capital Management LLC10,000$460.6K0.05%+10,000New
Elmwood Wealth Management, Inc.10,069$463.8K0.33%00.0%Unchanged
Advisors Asset Management, Inc.10,416$479.8K0.01%+228+2.2%Added
Public Employees Retirement Association of Colorado10,633$490.0K0.00%00.0%Unchanged
Supplemental Annuity Collective Trust of NJ11,000$506.7K0.18%00.0%Unchanged
Legato Capital Management LLC11,837$545.2K0.07%+155+1.3%Added
Teacher Retirement System of Texas13,988$644.0K0.00%−430−3.0%Reduced
Handelsbanken Fonder AB14,100$649.0K0.00%00.0%Unchanged
UBS Oconnor LLC14,676$676.0K0.02%−34,000−69.8%Reduced
Atom Investors LP15,247$702.3K0.12%+15,247New
Zurcher Kantonalbank (Zurich Cantonalbank)15,584$717.8K0.00%+3,961+34.1%Added
Balyasny Asset Management LLC15,851$730.1K0.00%+15,851New
TD Asset Management Inc16,230$747.6K0.00%+16,230New
Allianz Asset Management GmbH17,400$801.4K0.00%+4,200+31.8%Added
Arizona State Retirement System17,552$808.4K0.01%+3,074+21.2%Added
Campbell & CO Investment Adviser LLC17,973$827.8K0.07%+17,973New
SG Americas Securities, LLC18,606$857.0K0.01%−38,146−67.2%Reduced
Aquatic Capital Management LLC19,500$898.0K0.02%+4,200+27.5%Added
Chartwell Investment Partners, LLC20,520$945.0K0.03%−2,781−11.9%Reduced
Stifel Financial Corp20,881$961.8K0.00%+401+2.0%Added
Natixis Advisors, L.P.21,293$980.0K0.00%−731−3.3%Reduced
Bellevue Group AG22,000$1.01M0.02%−1,900−7.9%Reduced
Sanders Morris Harris LLC21,500$1.03M0.50%00.0%Unchanged
Rathbone Brothers plc23,666$1.09M0.01%00.0%Unchanged
Knott David M Jr23,866$1.10M0.42%00.0%Unchanged
Jump Financial, LLC24,000$1.11M0.04%+24,000New
NJ State Employees Deferred Compensation Plan25,000$1.15M0.16%00.0%Unchanged
Cinctive Capital Management LP27,600$1.27M0.09%+27,600New
Lighthouse Investment Partners, LLC27,775$1.28M0.09%+27,775New
Simplex Trading, LLC28,387$1.31M0.04%+17,652+164.4%Added
Jane Street Group, LLC29,390$1.35M0.00%+4,911+20.1%Added
UBS Group AG30,943$1.43M0.00%+25,061+426.1%Added
Standard Life Aberdeen plc32,036$1.48M0.00%+32,036New
Prelude Capital Management, LLC32,196$1.48M0.13%+16,438+104.3%Added
Renaissance Technologies LLC32,600$1.50M0.00%+10,700+48.9%Added
TLS Advisors LLC32,956$1.52M5.04%00.0%Unchanged
Royal Bank of Canada36,055$1.66M0.00%+8,934+32.9%Added
CIBC World Markets Inc.37,892$1.75M0.00%−7,480−16.5%Reduced
DekaBank Deutsche Girozentrale39,000$1.80M0.00%+19,000+95.0%Added
Boothbay Fund Management, LLC40,256$1.85M0.07%+40,256New
Nuveen Asset Management, LLC40,364$1.86M0.00%−1,331−3.2%Reduced
Tudor Investment Corp Et Al43,221$1.99M0.03%+43,221New