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Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q4 2023

Institutional positions in Xenon Pharmaceuticals Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
204
+26 vs. Q3 2023
Shares held
72.1M
+10.8M (+17.6%) vs. Q3 2023
Total value
$3.32B
+$1.23B (+58.6%) vs. Q3 2023
New holders
46
85 more added
Sold out
20
52 more reduced

3 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 204 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ4 2023: $3.32B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q3 2023.

Institutions holding XENE in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
HighVista Strategies LLC51,801$2.39M0.87%+16,546+46.9%Added
Alps Advisors Inc50,780$2.34M0.02%+3,431+7.2%Added
Erste Asset Management GmbH50,000$2.31M0.03%+15,000+42.9%Added
Envestnet Asset Management Inc45,229$2.08M0.00%+1,127+2.6%Added
Tudor Investment Corp Et Al43,221$1.99M0.03%+43,221New
Nuveen Asset Management, LLC40,364$1.86M0.00%−1,331−3.2%Reduced
Boothbay Fund Management, LLC40,256$1.85M0.07%+40,256New
DekaBank Deutsche Girozentrale39,000$1.80M0.00%+19,000+95.0%Added
CIBC World Markets Inc.37,892$1.75M0.00%−7,480−16.5%Reduced
Royal Bank of Canada36,055$1.66M0.00%+8,934+32.9%Added
TLS Advisors LLC32,956$1.52M5.04%00.0%Unchanged
Renaissance Technologies LLC32,600$1.50M0.00%+10,700+48.9%Added
Prelude Capital Management, LLC32,196$1.48M0.13%+16,438+104.3%Added
Standard Life Aberdeen plc32,036$1.48M0.00%+32,036New
UBS Group AG30,943$1.43M0.00%+25,061+426.1%Added
Jane Street Group, LLC29,390$1.35M0.00%+4,911+20.1%Added
Simplex Trading, LLC28,387$1.31M0.04%+17,652+164.4%Added
Lighthouse Investment Partners, LLC27,775$1.28M0.09%+27,775New
Cinctive Capital Management LP27,600$1.27M0.09%+27,600New
NJ State Employees Deferred Compensation Plan25,000$1.15M0.16%00.0%Unchanged
Jump Financial, LLC24,000$1.11M0.04%+24,000New
Knott David M Jr23,866$1.10M0.42%00.0%Unchanged
Rathbone Brothers plc23,666$1.09M0.01%00.0%Unchanged
Sanders Morris Harris LLC21,500$1.03M0.50%00.0%Unchanged
Bellevue Group AG22,000$1.01M0.02%−1,900−7.9%Reduced
Natixis Advisors, L.P.21,293$980.0K0.00%−731−3.3%Reduced
Stifel Financial Corp20,881$961.8K0.00%+401+2.0%Added
Chartwell Investment Partners, LLC20,520$945.0K0.03%−2,781−11.9%Reduced
Aquatic Capital Management LLC19,500$898.0K0.02%+4,200+27.5%Added
SG Americas Securities, LLC18,606$857.0K0.01%−38,146−67.2%Reduced
Campbell & CO Investment Adviser LLC17,973$827.8K0.07%+17,973New
Arizona State Retirement System17,552$808.4K0.01%+3,074+21.2%Added
Allianz Asset Management GmbH17,400$801.4K0.00%+4,200+31.8%Added
TD Asset Management Inc16,230$747.6K0.00%+16,230New
Balyasny Asset Management LLC15,851$730.1K0.00%+15,851New
Zurcher Kantonalbank (Zurich Cantonalbank)15,584$717.8K0.00%+3,961+34.1%Added
Atom Investors LP15,247$702.3K0.12%+15,247New
UBS Oconnor LLC14,676$676.0K0.02%−34,000−69.8%Reduced
Handelsbanken Fonder AB14,100$649.0K0.00%00.0%Unchanged
Teacher Retirement System of Texas13,988$644.0K0.00%−430−3.0%Reduced
Legato Capital Management LLC11,837$545.2K0.07%+155+1.3%Added
Supplemental Annuity Collective Trust of NJ11,000$506.7K0.18%00.0%Unchanged
Public Employees Retirement Association of Colorado10,633$490.0K0.00%00.0%Unchanged
Advisors Asset Management, Inc.10,416$479.8K0.01%+228+2.2%Added
Elmwood Wealth Management, Inc.10,069$463.8K0.33%00.0%Unchanged
Birchview Capital, LP10,000$460.6K0.36%00.0%Unchanged
Ghisallo Capital Management LLC10,000$460.6K0.05%+10,000New
Assetmark, Inc9,938$457.7K0.00%+2,835+39.9%Added
Guggenheim Capital LLC9,529$438.9K0.00%−1,603−14.4%Reduced
Moody Aldrich Partners LLC9,123$420.2K0.08%00.0%Unchanged
Capstone Investment Advisors, LLC8,861$408.1K0.01%+8,861New
China Universal Asset Management Co., Ltd.8,546$393.6K0.08%+6,895+417.6%Added
Brinker Capital Investments, LLC8,217$393.4K0.00%−7,185−46.6%Reduced
Orion Portfolio Solutions, LLC8,217$393.4K0.00%−7,185−46.6%Reduced
Squarepoint Ops LLC8,253$380.1K0.00%+8,253New
SEI Investments Co8,179$376.7K0.00%−158−1.9%Reduced
Aigen Investment Management, LP8,043$370.5K0.07%+8,043New
Omers Administration Corp7,700$354.7K0.00%+7,700New
Nebula Research & Development LLC7,281$335.4K0.10%+7,281New
American Century Companies Inc7,199$331.6K0.00%+7,199New
Axq Capital, LP7,006$322.7K0.09%+7,006New
Natixis7,000$322.4K0.00%−3,000−30.0%Reduced
Fox Run Management, L.L.C.6,595$303.8K0.08%+6,595New
Snowden Capital Advisors LLC5,723$263.6K0.01%−142−2.4%Reduced
Great West Life Assurance Co5,341$244.0K0.00%+848+18.9%Added
Vident Advisory, LLC5,292$243.7K0.01%+5,292New
Walleye Capital LLC5,054$232.8K0.00%−120,974−96.0%Reduced
Northwestern Mutual Wealth Management Co5,000$230.3K0.00%00.0%Unchanged
Weiss Multi-Strategy Advisers LLC5,000$230.0K0.01%+5,000New
ProShare Advisors LLC4,721$217.4K0.00%+4,721New
Oppenheimer Asset Management Inc.4,428$204.0K0.00%−1,783−28.7%Reduced
BNP Paribas Arbitrage, SA4,390$202.2K0.00%+2,707+160.8%Added
Citigroup Inc3,004$138.4K0.00%+138+4.8%Added
Advisor Group Holdings, Inc.2,665$122.7K0.00%−1,222−31.4%Reduced
Lynwood Capital Management Inc.2,500$115.2K0.51%+2,500New
Deutsche Bank AG2,495$114.9K0.00%00.0%Unchanged
Virtus ETF Advisers LLC2,245$103.4K0.07%−79−3.4%Reduced
IFP Advisors, Inc2,148$98.9K0.00%−30−1.4%Reduced
Proequities, Inc.2,000$92.1K0.01%00.0%Unchanged
The PNC Financial Services Group, Inc.1,980$91.2K0.00%+1,980New
Parallel Advisors, LLC1,125$51.8K0.00%+381+51.2%Added
Tower Research Capital LLC (TRC)1,014$46.7K0.00%+817+414.7%Added
Quarry LP1,000$46.1K0.02%−3,500−77.8%Reduced
LMR Partners LLP958$44.1K0.00%−24,042−96.2%Reduced
US Bancorp933$43.0K0.00%+674+260.2%Added
First Horizon Advisors, Inc.570$26.3K0.00%00.0%Unchanged
Accent Capital Management, LLC400$18.4K0.01%+400New
Cambridge Trust Co300$13.8K0.00%+300New
Daiwa Securities Group Inc.252$12.0K0.00%00.0%Unchanged
Householder Group Estate & Retirement Specialist, LLC215$9.00K0.00%−68−24.0%Reduced
Signaturefd, LLC129$5.94K0.00%+125+3,125.0%Added
Ronald Blue Trust, Inc.122$4.00K0.00%+122New
GWM Advisors LLC64$2.95K0.00%+64New
EverSource Wealth Advisors, LLC46$2.12K0.00%+46New
Whittier Trust Co of Nevada Inc38$1.75K0.00%00.0%Unchanged
CVA Family Office, LLC33$1.52K0.00%+33New
Headlands Technologies LLC23$1.06K0.00%−4−14.8%Reduced
GAMMA Investing LLC22$9950.00%+22New
Principal Securities, Inc.16$7370.00%+16New
SJS Investment Consulting Inc.5$2310.00%+2+66.7%Added