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NEXTBio Capital Management LP

SEC CIK
0002038158
Latest filing
Aug 14, 2026

The latest 13F from NEXTBio Capital Management LP covers Q2 2026 (filed Aug 14, 2026): 22 long positions worth $217.4M. The top 10 holdings make up 77.7% of the portfolio, and the largest is Protagonist Therapeutics, Inc (PTGX) at 12.4%. Livermore has 3 filings on Form 13F from this institution, going back to Q4 2025.

What changed in Q2 2026

Share counts compared with Q1 2026: how many positions were new, added to, reduced or sold out, and the biggest buys and sells. Dollar amounts are estimated at the quarter-end prices implied by the filing.

Full comparison
New
3
Est. +$8.42M
Added
7
Est. +$19.8M
Reduced
5
Est. −$7.64M
Sold out
5
Est. −$44.7M

Top 5 holdings

Share of this quarter's portfolio value

  1. PTGXProtagonist Therapeutics, Inc
    12.4%$26.9MHistory
  2. STTKShattuck Labs, Inc.
    11.9%$25.9MHistory
  3. CMPSCOMPASS Pathways plc
    11.6%$25.1MHistory
  4. GPCRStructure Therapeutics Inc.
    7.7%$16.8MHistory
  5. VORVor Biopharma Inc.
    7.5%$16.4MHistory

Share of portfolio

Top 5 holdings and the other 17 positions, by share of portfolio value

  1. PTGX12.4%
  2. STTK11.9%
  3. CMPS11.6%
  4. GPCR7.7%
  5. VOR7.5%
  6. Other 17 positions48.9%

Biggest buys

New and added positions, by estimated amount bought

  1. GPCRStructure Therapeutics Inc.
    +$9.62MAddedHistory
  2. STTKShattuck Labs, Inc.
    +$4.01MAddedHistory
  3. PHVSPharvaris N.V.
    +$3.74MNewHistory
  4. BIOABioAge Labs, Inc.
    +$2.47MNewHistory
  5. LBRXLB Pharmaceuticals Inc
    +$2.22MNewHistory

Largest weight increases

New and added positions, by percentage points of the portfolio gained

  1. GPCRStructure Therapeutics Inc.
    +4.73 pp3.0% → 7.7%History
  2. STTKShattuck Labs, Inc.
    +2.49 pp9.4% → 11.9%History
  3. PHVSPharvaris N.V.
    +1.72 pp0.0% → 1.7%History
  4. RYTMRhythm Pharmaceuticals, Inc.
    +1.64 pp5.1% → 6.7%History
  5. PVLAPalvella Therapeutics, Inc.
    +1.53 pp4.8% → 6.3%History

Biggest sells

Reduced and sold-out positions, by estimated amount sold

  1. TERNTerns Pharmaceuticals, Inc.
    −$31.9MSold outHistory
  2. CMPXCompass Therapeutics, Inc.
    −$4.49MSold outHistory
  3. OCSOculis Holding AG
    −$3.98MSold outHistory
  4. CMPSCOMPASS Pathways plc
    −$3.48MReducedHistory
  5. KALVKalVista Pharmaceuticals, Inc.
    −$2.65MSold outHistory

Largest weight decreases

Reduced and sold-out positions, by percentage points of the portfolio lost

  1. TERNTerns Pharmaceuticals, Inc.
    −14.80 pp14.8% → 0.0%History
  2. CMPXCompass Therapeutics, Inc.
    −2.08 pp2.1% → 0.0%History
  3. OCSOculis Holding AG
    −1.85 pp1.8% → 0.0%History
  4. EVMNEvommune, Inc.
    −1.24 pp2.0% → 0.7%History
  5. KALVKalVista Pharmaceuticals, Inc.
    −1.23 pp1.2% → 0.0%History

Metrics

13F metrics for Q2 2026, computed only from the numbers in the filings. Definitions below.

Portfolio value
$217.4M
+$2.03M (+0.9%) vs. prior quarter
Positions
22
−2 vs. prior quarter
Top 10 concentration
77.7%
Top 10 as share of value
Turnover
13.0%
Q2 2026, one quarter
Average holding period
2.9 quarters
Weighted by value

How these are calculated

  • Portfolio value: the market value of all long positions in the 13F, as reported at quarter end, excluding options.
  • Top 10 concentration: the combined value of the 10 largest positions as a share of portfolio value.
  • Turnover: the smaller of this quarter's estimated purchases and estimated sales, divided by the average of this and last quarter's portfolio value. Estimates multiply the change in shares by the quarter-end price implied by the filing (market value divided by shares); new positions use this quarter's value and sold-out positions last quarter's. Only positions reported in shares count, and it is not calculated when the previous quarter was not filed.
  • Average holding period: how many consecutive quarters each current position has been held (including this one; a quarter without the position or without a filing starts the count over), weighted by this quarter's value. Counting starts with the first 13F in Livermore (Q4 2025), so positions held before then are understated.

13F filings by quarter

3 quarters, going back to Q4 2025. Bars show each quarter's 13F portfolio value; quarters without a filing are left blank.

Peak $217.4M (Q2 2026)

Q4 2025: $170.5MQ1 2026: $215.4MQ2 2026: $217.4M
Q4 2025Q2 2026
13F filings of NEXTBio Capital Management LP by quarter
QuarterFiledPositionsValueTop 3 holdingsChangesFiling
Q2 2026Aug 14, 202622$217.4MPTGXSTTKCMPSvs. Q1 2026SEC
Q1 2026May 14, 202624$215.4MTERNPTGXSTTKvs. Q4 2025SEC
Q4 2025Feb 13, 202623$170.5MTERNPTGXVOR–SEC