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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

Key figures

Insider buysOpen market, last 90 days
0
Insider sellsLast 90 days, $33.1M in total
2
13F holdersQ2 2026, +27 vs. previous quarter
346
13F valueReported value at the end of Q2 2026
$9.30B
Superinvestors holdingAt the end of Q2 2026
1

Price chart

Superinvestors holding PTGX, Q2 2026

1 superinvestor reports holding Protagonist Therapeutics, Inc on Form 13F. Percentages are the stock's share of each portfolio.

Go to the superinvestors tab

Duquesne Family Office

Stanley Druckenmiller

0.6%

Protagonist Therapeutics, Inc's share of the portfolio

Shares
208,900
Value
$25.6M

Latest insider trades

Open-market purchases and sales by Protagonist Therapeutics, Inc insiders from Form 4, newest first.

See all insider trades
Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Sep 10, 2026 (view filing)9:17 PM ETSep 8-102 daysPatel Dinesh V PH DPresident and CEOSSale−125.0K$145.92−$18.2M−19.3%523.0K after3 lots10b5-1
Aug 12, 2026 (view filing)6:43 PM ETAug 10-112 daysPatel Dinesh V PH DPresident and CEOSSale−100.0K$148.91−$14.9M−16.0%523.5K after2 lots10b5-1
Jun 25, 2026 (view filing)Jun 232 daysWaddill William D.DirectorSSale−9.00K$117.94−$1.06M−53.5%7.83K after10b5-1
Jun 11, 2026 (view filing)Jun 101 dayWaddill William D.DirectorSSale−9.00K$107.68−$969.1K−53.5%7.83K after10b5-1
Jun 1, 2026 (view filing)May 293 daysWaddill William D.DirectorSSale−9.00K$99.64−$896.8K−53.5%7.83K after10b5-1
May 14, 2026 (view filing)May 122 daysPatel Dinesh V PH DPresident and CEOSSale−75.0K$100.12−$7.51M−12.5%523.5K afterAmended10b5-1
May 11, 2026 (view filing)May 7-84 daysGiraudo BryanDirectorSSale−41.1K$100.12−$4.12M−76.4%12.7K after2 lots
May 11, 2026 (view filing)May 7-84 daysGiraudo BryanDirectorSSale−18.0K$100.05−$1.80M−100.0%0 after2 lots
Apr 21, 2026 (view filing)Apr 201 dayAli AsifChief Financial OfficerSSale−1.75K$105.47−$184.6K−2.9%59.0K after
Mar 27, 2026 (view filing)Mar 261 dayMolina Arturo MDChief Medical OfficerSSale−15.0K$104.79−$1.57M−15.1%84.1K after

Top 10 13F holders, Q2 2026

The largest institutional positions in Protagonist Therapeutics, Inc at the end of Q2 2026; share changes are against Q1 2026.

See all 346 holders
Institutions holding PTGX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.10,307,837$1.26B0.02%+528,468+5.4%Added
Farallon Capital Management, L.L.C.6,348,906$778.2M4.56%00.0%Unchanged
RTW Investments, LP5,061,175$620.4M5.30%+2,1220.0%Added
Vanguard Portfolio Management LLC3,629,298$444.9M0.02%+148,087+4.3%Added
Wellington Management Group LLP3,416,781$418.8M0.07%−182,863−5.1%Reduced
UBS Group AG3,399,221$416.7M0.07%−1,778,575−34.4%Reduced
State Street Corp3,321,554$407.2M0.01%+204,805+6.6%Added
Vanguard Capital Management LLC2,853,394$349.8M0.01%+47,498+1.7%Added
Johnson & Johnson2,449,183$300.2M37.59%00.0%Unchanged
Invesco Ltd.2,340,667$286.9M0.02%+175,997+8.1%Added