Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 346
- +27 vs. Q1 2026
- Shares held
- 75.9M
- −177.5K (−0.2%) vs. Q1 2026
- Total value
- $9.30B
- +$1.29B (+16.1%) vs. Q1 2026
- New holders
- 62
- 141 more added
- Sold out
- 35
- 90 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.32B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.71B |
| Q2 2025 | 274 | $3.93B |
| Q1 2025 | 275 | $3.16B |
| Q4 2024 | 241 | $2.46B |
| Q3 2024 | 240 | $2.80B |
| Q2 2024 | 188 | $2.06B |
| Q1 2024 | 185 | $1.85B |
| Q4 2023 | 157 | $1.36B |
| Q3 2023 | 144 | $946.5M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.23B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $399.8M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.70B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 10,307,837 | $1.26B | 0.02% | +528,468+5.4% | Added |
| Farallon Capital Management, L.L.C. | 6,348,906 | $778.2M | 4.56% | 00.0% | Unchanged |
| RTW Investments, LP | 5,061,175 | $620.4M | 5.30% | +2,1220.0% | Added |
| Vanguard Portfolio Management LLC | 3,629,298 | $444.9M | 0.02% | +148,087+4.3% | Added |
| Wellington Management Group LLP | 3,416,781 | $418.8M | 0.07% | −182,863−5.1% | Reduced |
| UBS Group AG | 3,399,221 | $416.7M | 0.07% | −1,778,575−34.4% | Reduced |
| State Street Corp | 3,321,554 | $407.2M | 0.01% | +204,805+6.6% | Added |
| Vanguard Capital Management LLC | 2,853,394 | $349.8M | 0.01% | +47,498+1.7% | Added |
| Johnson & Johnson | 2,449,183 | $300.2M | 37.59% | 00.0% | Unchanged |
| Invesco Ltd. | 2,340,667 | $286.9M | 0.02% | +175,997+8.1% | Added |
| Price T Rowe Associates Inc | 2,149,662 | $263.5M | 0.03% | +484,165+29.1% | Added |
| Jupiter Topco LLC | 2,129,780 | $261.0M | 0.11% | +2,129,780 | New |
| Geode Capital Management, LLC | 1,741,209 | $213.5M | 0.01% | +71,838+4.3% | Added |
| Woodline Partners LP | 1,414,173 | $173.3M | 0.54% | 00.0% | Unchanged |
| Bank of America Corp | 1,324,498 | $162.4M | 0.01% | +29,064+2.2% | Added |
| Jennison Associates LLC | 1,151,681 | $141.2M | 0.08% | +79,670+7.4% | Added |
| Perceptive Advisors LLC | 981,879 | $120.4M | 1.87% | −249,000−20.2% | Reduced |
| ADAR1 Capital Management, LLC | 960,863 | $117.8M | 5.54% | −33,256−3.3% | Reduced |
| Morgan Stanley | 905,992 | $111.1M | 0.01% | −112,230−11.0% | Reduced |
| Alyeska Investment Group, L.P. | 889,298 | $109.0M | 0.28% | +296,101+49.9% | Added |
| Hood River Capital Management LLC | 882,738 | $108.2M | 0.78% | +53,453+6.4% | Added |
| Goldman Sachs Group Inc | 812,852 | $99.6M | 0.01% | +33,907+4.4% | Added |
| Driehaus Capital Management LLC | 731,053 | $89.6M | 0.52% | +10,125+1.4% | Added |
| Clearbridge Investments, LLC | 725,335 | $88.9M | 0.07% | +103,515+16.6% | Added |
| FMR LLC | 672,186 | $82.4M | 0.00% | +10,189+1.5% | Added |
| Northern Trust Corp | 666,105 | $81.7M | 0.01% | +78,137+13.3% | Added |
| American Century Companies Inc | 598,600 | $73.4M | 0.03% | +61,280+11.4% | Added |
| Charles Schwab Investment Management Inc | 583,774 | $71.6M | 0.01% | +30,818+5.6% | Added |
| Voya Investment Management LLC | 571,618 | $70.1M | 0.06% | +117,235+25.8% | Added |
| Pictet Asset Management Holding SA | 567,990 | $69.6M | 0.07% | −13,093−2.3% | Reduced |
| Franklin Resources Inc | 520,032 | $63.7M | 0.01% | +382,161+277.2% | Added |
| Vanguard Fiduciary Trust Co | 437,747 | $53.7M | 0.01% | +25,017+6.1% | Added |
| Lord, Abbett & Co. LLC | 398,994 | $48.9M | 0.14% | +235,535+144.1% | Added |
| Principal Financial Group Inc | 385,262 | $47.2M | 0.02% | +17,440+4.7% | Added |
| Bank of New York Mellon Corp | 358,300 | $43.9M | 0.01% | +16,835+4.9% | Added |
| Neuberger Berman Group LLC | 302,427 | $37.1M | 0.02% | +160,986+113.8% | Added |
| BNP Paribas Arbitrage, SA | 301,472 | $37.0M | 0.02% | +106,942+55.0% | Added |
| 683 Capital Management, LLC | 290,000 | $35.5M | 3.27% | −65,000−18.3% | Reduced |
| Nuveen, LLC | 284,085 | $34.8M | 0.01% | +156,171+122.1% | Added |
| Stephens Investment Management Group LLC | 281,832 | $34.5M | 0.37% | +281,832 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 259,972 | $31.9M | 0.03% | −46,065−15.1% | Reduced |
| Eagle Health Investments LP | 248,322 | $30.4M | 5.05% | +69,000+38.5% | Added |
| NEXTBio Capital Management LP | 219,333 | $26.9M | 12.37% | −10,286−4.5% | Reduced |
| Segall Bryant & Hamill, LLC | 214,724 | $26.3M | 0.31% | +2,010+0.9% | Added |
| SEB Asset Management AB | 209,963 | $25.7M | 0.10% | −22,453−9.7% | Reduced |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 208,900 | $25.6M | 0.59% | +49,200+30.8% | Added |
| Public Sector Pension Investment Board | 207,688 | $25.5M | 0.07% | −2,592−1.2% | Reduced |
| Citigroup Inc | 198,668 | $24.4M | 0.01% | +39,957+25.2% | Added |
| JPMorgan Chase & Co | 183,098 | $22.6M | 0.00% | +10,108+5.8% | Added |
| Dimensional Fund Advisors LP | 178,152 | $21.8M | 0.00% | −329,951−64.9% | Reduced |
| Affinity Asset Advisors, LLC | 172,125 | $21.1M | 1.03% | 00.0% | Unchanged |
| Fisher Asset Management, LLC | 170,524 | $20.9M | 0.01% | −3,447−2.0% | Reduced |
| Boxer Capital Management, LLC | 170,000 | $20.8M | 1.57% | 00.0% | Unchanged |
| Raymond James Financial Inc | 168,270 | $20.6M | 0.01% | −9,091−5.1% | Reduced |
| Nan Fung Trinity (HK) Ltd | 160,670 | $19.7M | 1.94% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 143,810 | $17.6M | 0.00% | −1,880−1.3% | Reduced |
| Deutsche Bank AG | 141,838 | $17.4M | 0.01% | +16,387+13.1% | Added |
| Rhumbline Advisers | 141,279 | $17.3M | 0.01% | −16,134−10.2% | Reduced |
| Nomura Asset Management International Inc. | 141,081 | $17.3M | 0.03% | +141,081 | New |
| TD Asset Management Inc | 134,950 | $16.5M | 0.01% | −48,750−26.5% | Reduced |
| Kennedy Capital Management, Inc. | 134,019 | $16.4M | 0.29% | −3,080−2.2% | Reduced |
| Legal & General Group Plc | 132,351 | $16.2M | 0.00% | −3,016−2.2% | Reduced |
| Russell Investments Group, Ltd. | 115,425 | $14.1M | 0.01% | +75,049+185.9% | Added |
| Marshall Wace, LLP | 109,017 | $13.4M | 0.01% | −519,058−82.6% | Reduced |
| Manufacturers Life Insurance Company, The | 108,555 | $13.3M | 0.01% | −19,263−15.1% | Reduced |
| UBS Asset Management Americas Inc | 107,094 | $13.1M | 0.00% | −343−0.3% | Reduced |
| Catalio Capital Management, LP | 106,799 | $13.1M | 2.46% | +106,799 | New |
| Swiss National Bank | 102,400 | $12.6M | 0.01% | +3,500+3.5% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 102,002 | $12.5M | 0.02% | −3,512−3.3% | Reduced |
| Opaleye Management Inc. | 100,000 | $12.3M | 1.11% | 00.0% | Unchanged |
| Assetmark, Inc | 98,687 | $12.1M | 0.02% | +52,245+112.5% | Added |
| SEI Investments Co | 92,749 | $11.4M | 0.01% | +9,552+11.5% | Added |
| Algert Global LLC | 87,698 | $10.8M | 0.13% | +9,228+11.8% | Added |
| Prudential Financial Inc | 85,180 | $10.4M | 0.01% | −10,055−10.6% | Reduced |
| Victory Capital Management Inc | 83,883 | $10.3M | 0.01% | +339+0.4% | Added |
| Axiom Investors LLC | 81,683 | $10.0M | 0.09% | −3,792−4.4% | Reduced |
| Wells Fargo & Company | 71,944 | $8.82M | 0.00% | +41,872+139.2% | Added |
| Alliancebernstein L.P. | 79,563 | $8.39M | 0.00% | +5,773+7.8% | Added |
| Nordea Investment Management AB | 64,964 | $7.94M | 0.01% | +13,143+25.4% | Added |
| Schroder Investment Management Group | 64,991 | $7.90M | 0.01% | −35,175−35.1% | Reduced |
| Knott David M Jr | 63,000 | $7.72M | 4.08% | 00.0% | Unchanged |
| Atika Capital Management LLC | 62,100 | $7.61M | 0.76% | 00.0% | Unchanged |
| Moody Aldrich Partners LLC | 59,601 | $7.31M | 1.31% | +5,708+10.6% | Added |
| California State Teachers Retirement System | 58,961 | $7.23M | 0.01% | +284+0.5% | Added |
| Eversept Partners, LP | 58,504 | $7.17M | 0.39% | +58,504 | New |
| Susquehanna International Group, LLP | 57,062 | $6.99M | 0.01% | −110,514−65.9% | Reduced |
| Great Lakes Advisors, LLC | 56,904 | $6.98M | 0.05% | −14,139−19.9% | Reduced |
| Creative Planning | 56,185 | $6.89M | 0.00% | +8,214+17.1% | Added |
| Bellevue Group AG | 55,682 | $6.83M | 0.14% | +41,235+285.4% | Added |
| First Trust Advisors LP | 54,865 | $6.73M | 0.00% | −32,993−37.6% | Reduced |
| KVP Capital Advisors, LP | 53,000 | $6.50M | 4.77% | 00.0% | Unchanged |
| Bessemer Group Inc | 52,074 | $6.38M | 0.01% | −2,104−3.9% | Reduced |
| Vanguard Asset Management, Ltd | 51,639 | $6.33M | 0.00% | +5,253+11.3% | Added |
| Castleark Management LLC | 50,570 | $6.20M | 0.17% | +50,570 | New |
| Granahan Investment Management Inc | 49,809 | $6.11M | 0.22% | +22,418+81.8% | Added |
| New York State Teachers Retirement System | 49,550 | $6.07M | 0.01% | +2,126+4.5% | Added |
| Northwestern Mutual Wealth Management Co | 48,894 | $5.99M | 0.00% | −126−0.3% | Reduced |
| Great West Life Assurance Co | 48,045 | $5.88M | 0.01% | +605+1.3% | Added |
| Silvercrest Asset Management Group LLC | 45,668 | $5.60M | 0.04% | −2,263−4.7% | Reduced |
| Seven Fleet Capital Management LP | 45,400 | $5.57M | 0.92% | +41,400+1,035.0% | Added |