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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2023

Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
144
−23 vs. Q2 2023
Shares held
56.7M
−20.1K (0.0%) vs. Q2 2023
Total value
$945.9M
−$621.0M (−39.6%) vs. Q2 2023
New holders
17
65 more added
Sold out
40
40 more reduced

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 144 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ3 2023: $945.9M
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2023.

Institutions holding PTGX in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc5,744,848$95.8M2.58%+1,968,948+52.1%Added
Farallon Capital Management, L.L.C.5,446,430$90.8M0.51%+935,000+20.7%Added
RTW Investments, LP5,415,514$90.3M1.91%00.0%Unchanged
BlackRock Inc.5,229,425$87.2M0.00%+220,152+4.4%Added
State Street Corp3,942,138$65.8M0.00%+390,152+11.0%Added
Vanguard Group Inc3,228,394$53.8M0.00%+80,639+2.6%Added
Johnson & Johnson2,449,183$40.9M15.05%00.0%Unchanged
Kynam Capital Management, LP1,818,657$30.3M5.04%+843,359+86.5%Added
Cowen and Company, LLC1,657,551$27.6M1.94%00.0%Unchanged
Geode Capital Management, LLC1,181,256$19.7M0.00%+104,072+9.7%Added
Braidwell LP1,109,150$18.5M0.58%+1,109,150New
Point72 Asset Management, L.P.1,108,140$18.5M0.06%+1,108,140New
Perceptive Advisors LLC1,054,273$17.6M0.59%−415,488−28.3%Reduced
Dimensional Fund Advisors LP941,274$15.7M0.01%−97,831−9.4%Reduced
Jefferies Financial Group Inc.835,561$13.9M0.35%+75,000+9.9%Added
Price T Rowe Associates Inc831,993$13.9M0.00%+3000.0%Added
683 Capital Management, LLC732,784$12.2M1.24%−81,216−10.0%Reduced
Adage Capital Partners GP, L.L.C.700,000$11.7M0.03%−592,711−45.9%Reduced
Candriam Luxembourg S.C.A.630,000$10.5M0.09%−95,000−13.1%Reduced
Northern Trust Corp562,688$9.39M0.00%+24,563+4.6%Added
HSBC Holdings PLC554,305$9.17M0.01%−6,150−1.1%Reduced
Nuveen Asset Management, LLC536,024$8.94M0.00%−399,937−42.7%Reduced
FMR LLC509,242$8.49M0.00%+1,835+0.4%Added
Goldman Sachs Group Inc467,203$7.79M0.00%−92,007−16.5%Reduced
Mangrove Partners439,314$7.33M0.75%+439,314New
Charles Schwab Investment Management Inc439,102$7.32M0.00%+19,492+4.6%Added
Morgan Stanley429,004$7.16M0.00%−149,017−25.8%Reduced
Ghost Tree Capital, LLC400,000$6.67M3.23%+175,000+77.8%Added
Rafferty Asset Management, LLC350,281$5.84M0.03%+64,822+22.7%Added
Two Sigma Investments, LP336,308$5.61M0.02%−40,165−10.7%Reduced
Eventide Asset Management, LLC320,000$5.34M0.10%00.0%Unchanged
Kennedy Capital Management, Inc.319,534$5.33M0.13%−84,114−20.8%Reduced
Two Sigma Advisers, LP316,900$5.29M0.01%−95,200−23.1%Reduced
Gratus Capital LLC292,869$4.89M0.33%+73,283+33.4%Added
Eversept Partners, LP286,748$4.78M0.53%+172,089+150.1%Added
Sio Capital Management, LLC248,127$4.14M1.28%+248,127New
Bank of America Corp239,038$3.99M0.00%−57,202−19.3%Reduced
JPMorgan Chase & Co232,290$3.87M0.00%−32,417−12.2%Reduced
Renaissance Technologies LLC226,268$3.77M0.01%−163,999−42.0%Reduced
Bank of New York Mellon Corp201,444$3.36M0.00%+1,869+0.9%Added
Readystate Asset Management LP184,347$3.07M0.26%−20,533−10.0%Reduced
Silvercrest Asset Management Group LLC180,462$3.01M0.02%+52,265+40.8%Added
ExodusPoint Capital Management, LP177,125$2.95M0.04%+162,471+1,108.7%Added
Barclays PLC176,837$2.95M0.00%−16,602−8.6%Reduced
Schonfeld Strategic Advisors LLC154,098$2.57M0.02%+154,098New
Citigroup Inc147,828$2.47M0.00%+40,307+37.5%Added
Twinbeech Capital LP147,346$2.46M0.05%+147,346New
BNP Paribas Arbitrage, SA143,964$2.40M0.01%−58,346−28.8%Reduced
Great Lakes Advisors, LLC141,559$2.36M0.02%−5,489−3.7%Reduced
Connor, Clark & Lunn Investment Management Ltd.139,494$2.33M0.01%−23,931−14.6%Reduced
UBS Oconnor LLC136,268$2.27M0.04%+69,174+103.1%Added
Walleye Capital LLC133,816$2.23M0.03%+81,155+154.1%Added
Jacobs Levy Equity Management, Inc129,011$2.15M0.01%−17,476−11.9%Reduced
Artia Global Partners LP112,340$1.87M0.78%00.0%Unchanged
TD Asset Management Inc110,800$1.85M0.00%+55,400+100.0%Added
Suvretta Capital Management, LLC108,308$1.81M0.10%+27,165+33.5%Added
Swiss National Bank100,600$1.68M0.00%+2,600+2.7%Added
Qube Research & Technologies Ltd91,735$1.53M0.00%+91,735New
UBS Group AG90,726$1.51M0.00%+25,186+38.4%Added
Healthcare of Ontario Pension Plan Trust Fund88,000$1.47M0.01%+88,000New
Alliancebernstein L.P.87,272$1.46M0.00%+7,072+8.8%Added
Rhumbline Advisers82,809$1.38M0.00%+4,898+6.3%Added
Wells Fargo & Company76,564$1.28M0.00%+5,513+7.8%Added
Manufacturers Life Insurance Company, The74,123$1.24M0.00%+8,231+12.5%Added
Algert Global LLC72,830$1.21M0.06%+45,600+167.5%Added
Deutsche Bank AG71,913$1.20M0.00%−789,411−91.7%Reduced
UBS Asset Management Americas Inc71,059$1.19M0.00%+6,281+9.7%Added
Moody Aldrich Partners LLC68,968$1.15M0.22%+27,108+64.8%Added
State of Wisconsin Investment Board61,481$1.03M0.00%+11,804+23.8%Added
Federated Hermes, Inc.60,234$1.00M0.00%+30,507+102.6%Added
Profund Advisors LLC58,716$979.4K0.05%+6,933+13.4%Added
Susquehanna International Group, LLP57,245$954.8K0.00%+41,281+258.6%Added
Campbell & CO Investment Adviser LLC56,577$943.7K0.11%+36,019+175.2%Added
California State Teachers Retirement System53,080$885.4K0.00%−4,568−7.9%Reduced
Knott David M Jr52,368$873.0K0.34%+52,368New
Citadel Advisors LLC50,796$847.3K0.00%−498,198−90.7%Reduced
Credit Suisse AG50,113$835.9K0.00%−12,721−20.2%Reduced
Ghisallo Capital Management LLC50,000$834.0K0.09%00.0%Unchanged
Public Sector Pension Investment Board49,000$817.3K0.01%−97,000−66.4%Reduced
Legal & General Group Plc44,765$746.7K0.00%+265+0.6%Added
AlphaCentric Advisors LLC43,500$725.6K0.41%+43,500New
Voya Investment Management LLC42,963$716.6K0.00%+1,374+3.3%Added
Alps Advisors Inc42,449$708.0K0.01%+368+0.9%Added
Invesco Ltd.40,901$682.2K0.00%−223,510−84.5%Reduced
SEI Investments Co40,216$670.8K0.00%−31,800−44.2%Reduced
Jane Street Group, LLC38,506$642.3K0.00%+16,697+76.6%Added
Birchview Capital, LP38,000$633.8K0.54%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.37,222$620.9K0.00%+1,555+4.4%Added
Jump Financial, LLC35,438$591.1K0.02%+21,070+146.6%Added
Hennion & Walsh Asset Management, Inc.31,666$528.2K0.03%+14,958+89.5%Added
Bellevue Group AG30,000$500.4K0.01%+30,000New
MetLife Investment Management28,596$477.0K0.00%00.0%Unchanged
American International Group, Inc.28,505$475.5K0.00%+2,411+9.2%Added
Ensign Peak Advisors, Inc28,400$473.7K0.00%+12,100+74.2%Added
Engineers Gate Manager LP25,854$431.2K0.02%+25,854New
New York State Common Retirement Fund23,201$387.0K0.00%+237+1.0%Added
Janus Henderson Group PLC21,775$363.5K0.00%+20+0.1%Added
Marshall Wace, LLP21,747$362.7K0.00%−142,753−86.8%Reduced
International Biotechnology Trust PLC19,900$331.9K0.11%00.0%Unchanged
Skandinaviska Enskilda Banken AB (publ)18,914$315.0K0.00%00.0%Unchanged