Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2021
Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 139
- +12 vs. Q1 2021
- Shares held
- 48.2M
- +3.82M (+8.6%) vs. Q1 2021
- Total value
- $2.16B
- +$1.01B (+88.1%) vs. Q1 2021
- New holders
- 27
- 60 more added
- Sold out
- 15
- 36 more reduced
Compare with Q1 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q2 2021
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 7,116,383 | $319.4M | 0.03% | +545,156+8.3% | Added |
| BVF Inc | 3,754,095 | $168.5M | 6.31% | −205,356−5.2% | Reduced |
| RTW Investments, LP | 3,507,390 | $157.4M | 2.38% | 00.0% | Unchanged |
| Consonance Capital Management LP | 3,446,874 | $154.7M | 18.62% | +737,165+27.2% | Added |
| BlackRock Inc. | 3,040,541 | $136.5M | 0.00% | +38,912+1.3% | Added |
| Johnson & Johnson Innovation - JJDC, Inc. | 2,449,183 | $109.9M | 11.24% | 00.0% | Unchanged |
| Farallon Capital Management, L.L.C. | 2,329,680 | $104.6M | 0.50% | −95,320−3.9% | Reduced |
| Vanguard Group Inc | 2,288,034 | $102.7M | 0.00% | +147,487+6.9% | Added |
| State Street Corp | 1,454,620 | $65.3M | 0.00% | −258,063−15.1% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 1,362,790 | $61.2M | 1.09% | +104,000+8.3% | Added |
| Point72 Asset Management, L.P. | 1,155,200 | $51.8M | 0.26% | +212,900+22.6% | Added |
| Price T Rowe Associates Inc | 986,254 | $44.3M | 0.00% | +72,664+8.0% | Added |
| Victory Capital Management Inc | 845,199 | $37.9M | 0.04% | +845,199 | New |
| Deutsche Bank AG | 821,722 | $36.9M | 0.02% | +796,161+3,114.7% | Added |
| Dimensional Fund Advisors LP | 791,016 | $35.5M | 0.01% | +134,915+20.6% | Added |
| Obermeyer Wood Investment Counsel, LLLP | 761,018 | $34.2M | 1.90% | +374,946+97.1% | Added |
| Geode Capital Management, LLC | 713,838 | $32.0M | 0.00% | +68,159+10.6% | Added |
| Novo Holdings A/S | 600,010 | $26.9M | 1.19% | −267,714−30.9% | Reduced |
| Adage Capital Partners GP, L.L.C. | 550,045 | $24.7M | 0.05% | −50,000−8.3% | Reduced |
| Loomis Sayles & Co L P | 536,920 | $24.1M | 0.03% | +536,920 | New |
| Baker Bros. Advisors LP | 455,276 | $20.4M | 0.09% | −980,916−68.3% | Reduced |
| Sofinnova Investments, Inc. | 449,082 | $20.2M | 1.22% | −205,818−31.4% | Reduced |
| Northern Trust Corp | 444,585 | $20.0M | 0.00% | +29,072+7.0% | Added |
| JPMorgan Chase & Co | 433,428 | $19.5M | 0.00% | −151,469−25.9% | Reduced |
| Citadel Advisors LLC | 403,208 | $18.1M | 0.02% | +204,990+103.4% | Added |
| Goldman Sachs Group Inc | 391,943 | $17.6M | 0.00% | −22,191−5.4% | Reduced |
| Rothschild & Co Asset Management US Inc. | 388,228 | $17.4M | 0.21% | −46,021−10.6% | Reduced |
| Tri Locum Partners LP | 341,650 | $15.3M | 6.42% | +84,564+32.9% | Added |
| Laurion Capital Management LP | 337,109 | $15.1M | 0.24% | +189,704+128.7% | Added |
| Opaleye Management Inc. | 330,222 | $14.8M | 2.46% | +33,222+11.2% | Added |
| Sphera Funds Management Ltd. | 302,965 | $13.6M | 1.29% | +100,831+49.9% | Added |
| Altium Capital Management LP | 282,445 | $12.7M | 2.94% | +44,091+18.5% | Added |
| Charles Schwab Investment Management Inc | 281,378 | $12.6M | 0.00% | +19,791+7.6% | Added |
| Two Sigma Advisers, LP | 256,075 | $11.5M | 0.03% | −90,600−26.1% | Reduced |
| D. E. Shaw & Co., Inc. | 248,235 | $11.1M | 0.01% | +47,255+23.5% | Added |
| Commodore Capital LP | 210,600 | $9.45M | 3.29% | −139,000−39.8% | Reduced |
| Pinz Capital Management, LP | 196,000 | $8.80M | 2.65% | +196,000 | New |
| International Biotechnology Trust PLC | 152,000 | $6.81M | 1.82% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 146,330 | $6.57M | 0.00% | +12,735+9.5% | Added |
| Twin Lakes Capital Management, LLC | 143,440 | $6.44M | 3.58% | +556+0.4% | Added |
| Affinity Asset Advisors, LLC | 140,100 | $6.29M | 3.00% | +90,100+180.2% | Added |
| Lord, Abbett & Co. LLC | 138,608 | $6.22M | 0.01% | +138,608 | New |
| Panagora Asset Management Inc | 137,198 | $6.16M | 0.03% | −92,315−40.2% | Reduced |
| Parkman Healthcare Partners LLC | 130,000 | $5.83M | 1.28% | +130,000 | New |
| Silvercrest Asset Management Group LLC | 119,391 | $5.36M | 0.04% | +119,391 | New |
| Polar Capital Holdings Plc | 119,203 | $5.35M | 0.03% | +119,203 | New |
| SEI Investments Co | 106,534 | $4.78M | 0.01% | +19,654+22.6% | Added |
| Emerald Advisers, LLC | 103,850 | $4.66M | 0.17% | +103,850 | New |
| EAM Investors, LLC | 101,019 | $4.53M | 0.70% | +101,019 | New |
| Iszo Capital Management LP | 93,883 | $4.21M | 1.53% | +93,883 | New |
| Swiss National Bank | 86,800 | $3.90M | 0.00% | +3,200+3.8% | Added |
| Candriam Luxembourg S.C.A. | 83,646 | $3.75M | 0.03% | +83,646 | New |
| Emerald Mutual Fund Advisers Trust | 76,965 | $3.45M | 0.11% | +76,965 | New |
| TD Asset Management Inc | 68,842 | $3.40M | 0.00% | +7,371+12.0% | Added |
| Allianz Asset Management GmbH | 74,260 | $3.33M | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 73,377 | $3.29M | 0.01% | −10,139−12.1% | Reduced |
| Citigroup Inc | 72,540 | $3.26M | 0.00% | −23,180−24.2% | Reduced |
| Kennedy Capital Management, Inc. | 71,947 | $3.23M | 0.07% | −3,571−4.7% | Reduced |
| Parametric Portfolio Associates LLC | 71,400 | $3.20M | 0.00% | +31,201+77.6% | Added |
| EAM Global Investors LLC | 70,185 | $3.15M | 0.87% | +70,185 | New |
| Morgan Stanley | 69,830 | $3.13M | 0.00% | +65,107+1,378.5% | Added |
| Bank of America Corp | 65,733 | $2.95M | 0.00% | +24,018+57.6% | Added |
| Bank of Montreal | 64,280 | $2.84M | 0.00% | −25,793−28.6% | Reduced |
| Federated Hermes, Inc. | 62,015 | $2.78M | 0.01% | +62,015 | New |
| State of Wisconsin Investment Board | 61,600 | $2.77M | 0.01% | +7,900+14.7% | Added |
| California State Teachers Retirement System | 57,003 | $2.56M | 0.00% | +3,880+7.3% | Added |
| Russell Investments Group, Ltd. | 54,004 | $2.42M | 0.00% | +3,271+6.4% | Added |
| Alliancebernstein L.P. | 45,900 | $2.06M | 0.00% | +15,300+50.0% | Added |
| Rhumbline Advisers | 40,812 | $1.83M | 0.00% | +7,597+22.9% | Added |
| Rafferty Asset Management, LLC | 39,192 | $1.76M | 0.01% | −36,784−48.4% | Reduced |
| New York State Common Retirement Fund | 35,790 | $1.61M | 0.00% | +8,290+30.1% | Added |
| Gyon Technologies Capital Management, LP | 35,056 | $1.57M | 0.52% | +35,056 | New |
| Susquehanna Fundamental Investments, LLC | 34,620 | $1.55M | 0.03% | −13,000−27.3% | Reduced |
| Ensign Peak Advisors, Inc | 33,230 | $1.49M | 0.00% | 00.0% | Unchanged |
| Skandinaviska Enskilda Banken AB (publ) | 30,628 | $1.38M | 0.01% | +30,628 | New |
| Wells Fargo & Company | 30,018 | $1.35M | 0.00% | −8,417−21.9% | Reduced |
| Prudential Financial Inc | 29,845 | $1.34M | 0.00% | −3,770−11.2% | Reduced |
| Nuveen Asset Management, LLC | 166,325 | $1.29M | 0.00% | +21,625+14.9% | Added |
| UBS Asset Management Americas Inc | 27,598 | $1.24M | 0.00% | +2,598+10.4% | Added |
| Credit Suisse AG | 27,455 | $1.23M | 0.00% | +6,215+29.3% | Added |
| AQR Capital Management LLC | 26,608 | $1.19M | 0.00% | −3,779−12.4% | Reduced |
| HighVista Strategies LLC | 25,853 | $1.16M | 0.82% | +25,853 | New |
| American International Group, Inc. | 23,165 | $1.04M | 0.00% | +2,638+12.9% | Added |
| Manufacturers Life Insurance Company, The | 23,025 | $1.03M | 0.00% | +2,986+14.9% | Added |
| King Wealth | 22,000 | $987.0K | 0.20% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 21,333 | $957.0K | 0.00% | −12,801−37.5% | Reduced |
| Franklin Street Advisors Inc | 20,250 | $909.0K | 0.08% | −2,000−9.0% | Reduced |
| Monashee Investment Management LLC | 20,000 | $898.0K | 0.11% | +20,000 | New |
| J. Goldman & Co LP | 19,986 | $897.0K | 0.06% | −29,593−59.7% | Reduced |
| ProShare Advisors LLC | 18,621 | $836.0K | 0.00% | +3,254+21.2% | Added |
| Invesco Ltd. | 18,122 | $814.0K | 0.00% | +8,019+79.4% | Added |
| Principal Financial Group Inc | 16,540 | $743.0K | 0.00% | +8,364+102.3% | Added |
| Voya Investment Management LLC | 16,250 | $729.0K | 0.00% | +1,156+7.7% | Added |
| Millennium Management LLC | 15,440 | $693.0K | 0.00% | +4,548+41.8% | Added |
| MetLife Investment Management | 15,088 | $677.1K | 0.01% | +1,564+11.6% | Added |
| Kestra Advisory Services, LLC | 13,939 | $626.0K | 0.01% | +310+2.3% | Added |
| DekaBank Deutsche Girozentrale | 14,000 | $616.0K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 12,561 | $563.0K | 0.00% | +2,016+19.1% | Added |
| Bingham Osborn & Scarborough LLC | 11,640 | $522.0K | 0.04% | −4,000−25.6% | Reduced |
| Metropolitan Life Insurance Co | 11,552 | $518.5K | 0.01% | +2,268+24.4% | Added |