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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2024

Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
188
+4 vs. Q1 2024
Shares held
59.1M
−844.0K (−1.4%) vs. Q1 2024
Total value
$2.05B
+$313.9M (+18.1%) vs. Q1 2024
New holders
30
63 more added
Sold out
26
68 more reduced

1 institution that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 188 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ2 2024: $2.05B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2024.

Institutions holding PTGX in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Farallon Capital Management, L.L.C.5,840,773$202.4M1.19%+101,800+1.8%Added
BlackRock Inc.5,758,112$199.5M0.00%+188,627+3.4%Added
RTW Investments, LP5,286,404$183.2M2.84%−29,110−0.5%Reduced
BVF Inc3,319,290$115.0M3.22%−436,700−11.6%Reduced
Vanguard Group Inc3,243,473$112.4M0.00%+50,502+1.6%Added
Johnson & Johnson2,449,183$84.9M21.18%00.0%Unchanged
State Street Corp2,082,324$72.2M0.00%−1,190,161−36.4%Reduced
Jefferies Financial Group Inc.2,040,561$70.7M1.39%+860,000+72.8%Added
Adage Capital Partners GP, L.L.C.2,001,342$69.3M0.13%−217,526−9.8%Reduced
ADAR1 Capital Management, LLC1,603,932$55.6M11.19%+818,277+104.2%Added
Geode Capital Management, LLC1,371,169$47.5M0.00%+77,430+6.0%Added
Perceptive Advisors LLC1,268,735$44.0M1.06%+274,412+27.6%Added
Price T Rowe Associates Inc1,209,542$41.9M0.01%+390,246+47.6%Added
Cowen and Company, LLC1,182,268$41.0M1.13%−375,368−24.1%Reduced
Millennium Management LLC958,283$33.2M0.03%+915,418+2,135.6%Added
Fairmount Funds Management LLC931,890$32.3M3.65%00.0%Unchanged
Point72 Asset Management, L.P.909,734$31.5M0.10%−290,168−24.2%Reduced
Deutsche Bank AG908,348$31.5M0.01%−2,458−0.3%Reduced
Woodline Partners LP822,173$28.5M0.27%+185,217+29.1%Added
Kynam Capital Management, LP800,000$27.7M2.90%−344,242−30.1%Reduced
Dimensional Fund Advisors LP616,172$21.3M0.01%−175,172−22.1%Reduced
683 Capital Management, LLC604,449$20.9M2.20%−95,551−13.7%Reduced
Goldman Sachs Group Inc590,761$20.5M0.00%+65,721+12.5%Added
Marshall Wace, LLP572,177$19.8M0.03%−404,716−41.4%Reduced
Driehaus Capital Management LLC556,835$19.3M0.19%−3,695−0.7%Reduced
Charles Schwab Investment Management Inc525,653$18.2M0.00%+29,091+5.9%Added
Northern Trust Corp508,459$17.6M0.00%−30,536−5.7%Reduced
Eversept Partners, LP505,836$17.5M1.34%+94,358+22.9%Added
Qube Research & Technologies Ltd453,152$15.7M0.03%+390,997+629.1%Added
Mangrove Partners439,314$15.2M1.37%00.0%Unchanged
FMR LLC434,459$15.1M0.00%−31,626−6.8%Reduced
Gratus Capital LLC418,346$14.5M0.58%+10,173+2.5%Added
JPMorgan Chase & Co376,588$13.0M0.00%+139,148+58.6%Added
Nuveen Asset Management, LLC373,992$13.0M0.00%−304,209−44.9%Reduced
UBS Asset Management Americas Inc369,955$12.8M0.00%+34,637+10.3%Added
Eagle Asset Management Inc357,633$12.6M0.07%+357,633New
Susquehanna International Group, LLP355,586$12.3M0.02%+283,768+395.1%Added
Checkpoint Capital L.P.355,000$12.3M7.42%+74,699+26.6%Added
Morgan Stanley345,293$12.0M0.00%−1,534,585−81.6%Reduced
Bank of America Corp300,481$10.4M0.00%+33,930+12.7%Added
Renaissance Technologies LLC297,467$10.3M0.02%+264,900+813.4%Added
Kennedy Capital Management, Inc.290,082$10.1M0.21%−7,986−2.7%Reduced
Candriam Luxembourg S.C.A.273,818$9.49M0.06%−86,182−23.9%Reduced
Bank of New York Mellon Corp204,299$7.08M0.00%+17,065+9.1%Added
Rubric Capital Management LP198,059$6.86M0.18%00.0%Unchanged
Silvercrest Asset Management Group LLC191,168$6.62M0.05%+2,425+1.3%Added
Jane Street Group, LLC169,311$5.87M0.01%+88,041+108.3%Added
Northwestern Mutual Wealth Management Co157,788$5.47M0.01%+157,788New
Algert Global LLC152,079$5.27M0.18%+4,236+2.9%Added
TD Asset Management Inc148,302$5.14M0.00%+39,850+36.7%Added
Moody Aldrich Partners LLC134,215$4.65M0.91%+33,696+33.5%Added
First Trust Advisors LP131,810$4.57M0.00%+71,147+117.3%Added
Jacobs Levy Equity Management, Inc129,011$4.47M0.02%00.0%Unchanged
Artia Global Partners LP124,440$4.31M1.11%00.0%Unchanged
Segall Bryant & Hamill, LLC118,562$4.11M0.07%+118,562New
Two Sigma Advisers, LP116,600$4.04M0.01%−80,100−40.7%Reduced
Manufacturers Life Insurance Company, The114,406$3.96M0.00%+24,749+27.6%Added
Opaleye Management Inc.105,000$3.64M0.83%−7,700−6.8%Reduced
Alliancebernstein L.P.95,169$3.30M0.00%+9,769+11.4%Added
Great Lakes Advisors, LLC93,479$3.24M0.03%−3,681−3.8%Reduced
Invesco Ltd.88,434$3.06M0.00%+60,075+211.8%Added
Swiss National Bank85,900$2.98M0.00%−4,800−5.3%Reduced
Rhumbline Advisers84,975$2.94M0.00%−140.0%Reduced
Cubist Systematic Strategies, LLC84,202$2.92M0.05%+78,207+1,304.5%Added
Connor, Clark & Lunn Investment Management Ltd.82,791$2.87M0.01%−10,395−11.2%Reduced
Two Sigma Investments, LP82,637$2.86M0.01%−74,957−47.6%Reduced
Trexquant Investment LP80,614$2.79M0.04%−21,765−21.3%Reduced
Rafferty Asset Management, LLC75,270$2.61M0.01%−163,938−68.5%Reduced
Cannon Global Investment Management, LLC69,900$2.42M11.28%+69,900New
UBS Oconnor LLC68,231$2.36M0.07%−41,099−37.6%Reduced
UBS Group AG66,981$2.32M0.00%−110,565−62.3%Reduced
Voya Investment Management LLC65,066$2.25M0.00%−4,377−6.3%Reduced
Dark Forest Capital Management LP60,962$2.11M0.39%+60,962New
Old Mission Capital LLC58,916$2.04M0.05%+58,916New
State of Wisconsin Investment Board55,951$1.94M0.01%+14,465+34.9%Added
Legal & General Group Plc53,286$1.85M0.00%+2,600+5.1%Added
Knott David M Jr52,368$1.81M0.72%00.0%Unchanged
Schonfeld Strategic Advisors LLC49,064$1.70M0.01%+49,064New
Y-Intercept (Hong Kong) Ltd48,127$1.67M0.09%+26,678+124.4%Added
Birchview Capital, LP48,000$1.66M1.54%00.0%Unchanged
Alps Advisors Inc45,772$1.59M0.01%+4,673+11.4%Added
California State Teachers Retirement System43,795$1.52M0.00%−3,444−7.3%Reduced
SEI Investments Co41,763$1.45M0.00%+50.0%Added
Barclays PLC39,240$1.36M0.00%−22,579−36.5%Reduced
Hennion & Walsh Asset Management, Inc.37,880$1.31M0.07%+2,985+8.6%Added
Seven Eight Capital, LP36,793$1.27M0.13%+29,810+426.9%Added
Catalyst Funds Management Pty Ltd36,600$1.27M0.34%+29,080+386.7%Added
Franklin Resources Inc35,917$1.24M0.00%+4,073+12.8%Added
Jackson Creek Investment Advisors LLC34,651$1.20M0.44%−61−0.2%Reduced
MetLife Investment Management33,805$1.17M0.01%+5,209+18.2%Added
Capula Management Ltd32,963$1.14M0.01%+32,963New
Mirae Asset Global ETFs Holdings Ltd.32,120$1.11M0.00%+32,120New
Corebridge Financial, Inc.31,440$1.09M0.01%+31,440New
Los Angeles Capital Management LLC30,827$1.07M0.00%00.0%Unchanged
Suvretta Capital Management, LLC30,500$1.06M0.04%00.0%Unchanged
Wells Fargo & Company30,190$1.05M0.00%+397+1.3%Added
American Century Companies Inc27,311$946.3K0.00%−133,009−83.0%Reduced
Ensign Peak Advisors, Inc27,036$936.8K0.00%00.0%Unchanged
AQR Capital Management LLC25,055$868.2K0.00%−55,952−69.1%Reduced
Gsa Capital Partners LLP25,029$867.0K0.06%−30,330−54.8%Reduced