Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2023
Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 138
- +2 vs. Q4 2022
- Shares held
- 53.2M
- +4.49M (+9.2%) vs. Q4 2022
- Total value
- $1.22B
- +$693.0M (+130.4%) vs. Q4 2022
- New holders
- 34
- 44 more added
- Sold out
- 32
- 44 more reduced
1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| RTW Investments, LP | 4,600,799 | $105.8M | 2.20% | +1,008,813+28.1% | Added |
| BlackRock Inc. | 4,402,217 | $101.3M | 0.00% | +750,060+20.5% | Added |
| BVF Inc | 3,775,900 | $86.8M | 3.17% | +3,775,900 | New |
| Vanguard Group Inc | 3,241,293 | $74.5M | 0.00% | +143,579+4.6% | Added |
| Farallon Capital Management, L.L.C. | 2,615,014 | $60.1M | 0.36% | −1,036,873−28.4% | Reduced |
| Adage Capital Partners GP, L.L.C. | 2,558,000 | $58.8M | 0.13% | +1,790,955+233.5% | Added |
| Johnson & Johnson | 2,449,183 | $56.3M | 18.32% | 00.0% | Unchanged |
| State Street Corp | 2,413,701 | $55.5M | 0.00% | −1,379,225−36.4% | Reduced |
| Cormorant Asset Management, LP | 1,700,000 | $39.1M | 2.58% | +1,700,000 | New |
| Morgan Stanley | 1,570,510 | $36.1M | 0.00% | −868,007−35.6% | Reduced |
| Kynam Capital Management, LP | 1,375,000 | $31.6M | 4.09% | +854,078+164.0% | Added |
| Marshall Wace, LLP | 1,366,080 | $31.4M | 0.08% | −88,366−6.1% | Reduced |
| Dimensional Fund Advisors LP | 1,262,259 | $29.0M | 0.01% | +185,033+17.2% | Added |
| Citadel Advisors LLC | 1,164,680 | $26.8M | 0.03% | −1,190,634−50.6% | Reduced |
| Millennium Management LLC | 1,122,342 | $25.8M | 0.03% | −223,047−16.6% | Reduced |
| Perceptive Advisors LLC | 965,152 | $22.2M | 0.66% | +965,152 | New |
| Deutsche Bank AG | 958,891 | $22.1M | 0.01% | +33,229+3.6% | Added |
| Geode Capital Management, LLC | 925,993 | $21.3M | 0.00% | +46,102+5.2% | Added |
| Nuveen Asset Management, LLC | 828,471 | $19.1M | 0.01% | +467,757+129.7% | Added |
| 683 Capital Management, LLC | 791,000 | $18.2M | 1.63% | +583,200+280.7% | Added |
| Bank of America Corp | 766,990 | $17.6M | 0.00% | +422,043+122.4% | Added |
| Renaissance Technologies LLC | 690,867 | $15.9M | 0.02% | +432,000+166.9% | Added |
| Woodline Partners LP | 618,615 | $14.2M | 0.20% | +106,475+20.8% | Added |
| Barclays PLC | 583,737 | $13.4M | 0.01% | +328,850+129.0% | Added |
| Candriam Luxembourg S.C.A. | 625,000 | $13.2M | 0.09% | +625,000 | New |
| Voloridge Investment Management, LLC | 465,323 | $10.7M | 0.05% | +297,954+178.0% | Added |
| Goldman Sachs Group Inc | 459,450 | $10.6M | 0.00% | −157,274−25.5% | Reduced |
| Two Sigma Advisers, LP | 449,800 | $10.3M | 0.03% | −153,700−25.5% | Reduced |
| Jennison Associates LLC | 428,938 | $9.87M | 0.01% | +428,938 | New |
| Northern Trust Corp | 422,636 | $9.72M | 0.00% | +4,029+1.0% | Added |
| Price T Rowe Associates Inc | 415,274 | $9.55M | 0.00% | +415,274 | New |
| Charles Schwab Investment Management Inc | 361,158 | $8.31M | 0.00% | +21,137+6.2% | Added |
| Kennedy Capital Management, Inc. | 331,282 | $7.62M | 0.22% | −18,851−5.4% | Reduced |
| Two Sigma Investments, LP | 307,700 | $7.08M | 0.02% | −184,265−37.5% | Reduced |
| OrbiMed Advisors LLC | 301,000 | $6.92M | 0.14% | +301,000 | New |
| Invesco Ltd. | 277,936 | $6.39M | 0.00% | +246,384+780.9% | Added |
| BNP Paribas Arbitrage, SA | 237,624 | $5.47M | 0.01% | +146,599+161.1% | Added |
| Ghost Tree Capital, LLC | 225,000 | $5.17M | 1.96% | +225,000 | New |
| Allspring Global Investments Holdings, LLC | 223,664 | $5.14M | 0.01% | +217,761+3,689.0% | Added |
| Jacobs Levy Equity Management, Inc | 220,991 | $5.08M | 0.03% | −63,124−22.2% | Reduced |
| Gratus Capital LLC | 211,731 | $4.87M | 0.37% | −7,328−3.3% | Reduced |
| D. E. Shaw & Co., Inc. | 199,516 | $4.59M | 0.01% | +11,480+6.1% | Added |
| Citigroup Inc | 192,349 | $4.42M | 0.01% | +44,281+29.9% | Added |
| Bank of New York Mellon Corp | 168,533 | $3.88M | 0.00% | +4,208+2.6% | Added |
| Rafferty Asset Management, LLC | 153,387 | $3.53M | 0.02% | −141,961−48.1% | Reduced |
| Great Lakes Advisors, LLC | 150,484 | $3.46M | 0.03% | +150,484 | New |
| Schonfeld Strategic Advisors LLC | 148,992 | $3.43M | 0.03% | +148,992 | New |
| Public Sector Pension Investment Board | 146,000 | $3.36M | 0.03% | +146,000 | New |
| Tri Locum Partners LP | 133,452 | $3.07M | 0.93% | +133,452 | New |
| Walleye Capital LLC | 127,370 | $2.93M | 0.06% | −396,932−75.7% | Reduced |
| Susquehanna International Group, LLP | 124,084 | $2.85M | 0.00% | +57,053+85.1% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 122,024 | $2.81M | 0.02% | −72,680−37.3% | Reduced |
| UBS Group AG | 115,939 | $2.67M | 0.00% | −109,590−48.6% | Reduced |
| Silvercrest Asset Management Group LLC | 113,355 | $2.61M | 0.02% | −127,390−52.9% | Reduced |
| UBS Oconnor LLC | 108,473 | $2.49M | 0.06% | +108,473 | New |
| JPMorgan Chase & Co | 106,133 | $2.44M | 0.00% | −197,029−65.0% | Reduced |
| Silverarc Capital Management, LLC | 105,486 | $2.43M | 1.09% | +105,486 | New |
| Walleye Trading LLC | 105,360 | $2.42M | 0.09% | +55,851+112.8% | Added |
| Thrivent Financial for Lutherans | 100,993 | $2.32M | 0.01% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 100,086 | $2.30M | 0.00% | −98,883−49.7% | Reduced |
| Franklin Resources Inc | 32,533 | $2.29M | 0.00% | +17,785+120.6% | Added |
| Voya Investment Management LLC | 94,057 | $2.16M | 0.00% | −45,342−32.5% | Reduced |
| AXA S.A. | 86,500 | $1.99M | 0.01% | −21,200−19.7% | Reduced |
| Swiss National Bank | 79,700 | $1.83M | 0.00% | −9,200−10.3% | Reduced |
| Rhumbline Advisers | 74,709 | $1.72M | 0.00% | +3,556+5.0% | Added |
| Jump Financial, LLC | 67,700 | $1.56M | 0.06% | +67,700 | New |
| Prudential Financial Inc | 67,293 | $1.55M | 0.00% | +67,293 | New |
| Cubist Systematic Strategies, LLC | 64,978 | $1.49M | 0.01% | +13,472+26.2% | Added |
| UBS Asset Management Americas Inc | 64,778 | $1.49M | 0.00% | +64,778 | New |
| Simplex Trading, LLC | 63,059 | $1.45M | 0.07% | +63,059 | New |
| Jane Street Group, LLC | 56,216 | $1.29M | 0.00% | +325+0.6% | Added |
| Alliancebernstein L.P. | 54,200 | $1.25M | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 49,714 | $1.14M | 0.00% | −988−1.9% | Reduced |
| FMR LLC | 48,320 | $1.11M | 0.00% | −20,206−29.5% | Reduced |
| Financial Enhancement Group LLC | 41,818 | $1.06M | 0.21% | +41,818 | New |
| Los Angeles Capital Management LLC | 45,473 | $1.05M | 0.00% | −31,517−40.9% | Reduced |
| Manufacturers Life Insurance Company, The | 44,855 | $1.03M | 0.00% | +26,337+142.2% | Added |
| Vontobel Holding Ltd. | 40,000 | $920.0K | 0.01% | 00.0% | Unchanged |
| Credit Suisse AG | 38,001 | $874.0K | 0.00% | +6,764+21.7% | Added |
| Birchview Capital, LP | 38,000 | $874.0K | 0.68% | 00.0% | Unchanged |
| Tudor Investment Corp Et Al | 37,340 | $859.0K | 0.02% | +37,340 | New |
| State of Wisconsin Investment Board | 36,169 | $831.9K | 0.00% | −76,026−67.8% | Reduced |
| SEI Investments Co | 35,639 | $819.7K | 0.00% | −306−0.9% | Reduced |
| Wells Fargo & Company | 33,964 | $781.2K | 0.00% | +33,927+91,694.6% | Added |
| Alps Advisors Inc | 32,415 | $745.5K | 0.01% | −934−2.8% | Reduced |
| Federated Hermes, Inc. | 29,653 | $682.0K | 0.00% | −17,155−36.6% | Reduced |
| TD Asset Management Inc | 29,000 | $667.0K | 0.00% | +29,000 | New |
| Profund Advisors LLC | 28,800 | $662.4K | 0.04% | +28,800 | New |
| STRS Ohio | 28,500 | $655.0K | 0.00% | +13,200+86.3% | Added |
| New York State Common Retirement Fund | 27,692 | $636.9K | 0.00% | +19+0.1% | Added |
| Mirae Asset Global Investments Co., Ltd. | 27,629 | $635.5K | 0.00% | +7,752+39.0% | Added |
| Mackenzie Financial Corp | 27,504 | $632.6K | 0.00% | +27,504 | New |
| Belvedere Trading LLC | 24,011 | $552.3K | 0.24% | +24,011 | New |
| MetLife Investment Management | 23,914 | $550.0K | 0.00% | 00.0% | Unchanged |
| American International Group, Inc. | 22,456 | $516.5K | 0.00% | +447+2.0% | Added |
| Allianz Asset Management GmbH | 21,500 | $494.5K | 0.00% | 00.0% | Unchanged |
| Algert Global LLC | 21,060 | $484.4K | 0.02% | −63,112−75.0% | Reduced |
| Legal & General Group Plc | 19,136 | $440.1K | 0.00% | +4,728+32.8% | Added |
| SG Americas Securities, LLC | 18,515 | $426.0K | 0.01% | −38,606−67.6% | Reduced |
| Ameriprise Financial Inc | 18,358 | $422.2K | 0.00% | +18,358 | New |