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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2023

Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
138
+2 vs. Q4 2022
Shares held
53.2M
+4.49M (+9.2%) vs. Q4 2022
Total value
$1.22B
+$693.0M (+130.4%) vs. Q4 2022
New holders
34
44 more added
Sold out
32
44 more reduced

1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 138 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ1 2023: $1.22B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2022.

Institutions holding PTGX in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
CM Wealth Advisors LLC17,285$402.0K0.08%+17,285New
Janus Henderson Group PLC17,250$397.0K0.00%+17,250New
DekaBank Deutsche Girozentrale15,800$357.0K0.00%00.0%Unchanged
American Century Companies Inc15,617$351.2K0.00%+4,561+41.3%Added
Public Employees Retirement System of Ohio15,014$345.0K0.00%00.0%Unchanged
Mariner, LLC14,072$324.0K0.00%+3,423+32.1%Added
Obermeyer Wood Investment Counsel, LLLP13,688$314.8K0.02%−662−4.6%Reduced
Principal Financial Group Inc13,523$311.0K0.00%+1,785+15.2%Added
Campbell & CO Investment Adviser LLC12,425$285.8K0.05%+12,425New
Franklin Street Advisors Inc12,220$281.0K0.03%−30,000−71.1%Reduced
King Wealth12,000$276.0K0.06%−10,000−45.5%Reduced
Cerity Partners LLC11,990$275.8K0.00%+11,990New
Zacks Investment Management11,861$272.8K0.00%+11,861New
Fred Alger Management, LLC11,605$266.9K0.00%+11,605New
Teacher Retirement System of Texas11,367$261.0K0.00%+239+2.1%Added
State Board of Administration of Florida Retirement System11,323$260.4K0.00%00.0%Unchanged
Arizona State Retirement System10,691$245.9K0.00%+304+2.9%Added
Virtus ETF Advisers LLC10,286$236.6K0.13%−3,949−27.7%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)10,160$233.7K0.00%+1,624+19.0%Added
Engineers Gate Manager LP9,278$213.4K0.01%−5,910−38.9%Reduced
ProShare Advisors LLC8,886$204.4K0.00%+8,886New
E Fund Management Co., Ltd.8,713$200.0K0.01%−6,769−43.7%Reduced
Amalgamated Bank4,729$109.0K0.00%−1,036−18.0%Reduced
Ameritas Investment Partners, Inc.3,501$80.5K0.00%00.0%Unchanged
Royal Bank of Canada2,634$61.0K0.00%−2,909−52.5%Reduced
Metropolitan Life Insurance Co2,520$58.0K0.00%−401−13.7%Reduced
Nisa Investment Advisors, LLC2,049$47.0K0.00%00.0%Unchanged
Great West Life Assurance Co1,982$46.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,658$38.0K0.00%−89−5.1%Reduced
China Universal Asset Management Co., Ltd.667$15.3K0.01%+167+33.4%Added
Leonteq Securities AG470$10.8K0.00%00.0%Unchanged
Global Retirement Partners, LLC300$7.33K0.00%−700−70.0%Reduced
Caption Management, LLC243$5.59K0.00%−39,757−99.4%Reduced
Daiwa Securities Group Inc.163$4.00K0.00%00.0%Unchanged
Truvestments Capital LLC131$3.01K0.00%−214−62.0%Reduced
TCI Wealth Advisors, Inc.129$2.97K0.00%+129New
The PNC Financial Services Group, Inc.115$2.65K0.00%+115New
Covestor Ltd10$00.00%00.0%Unchanged
Bain Capital Life Sciences Investors, LLC0$00.00%−2,364,410−100.0%Sold out
Braidwell LP0$00.00%−927,800−100.0%Sold out
Deep Track Capital, LP0$00.00%−871,493−100.0%Sold out
Sio Capital Management, LLC0$00.00%−434,635−100.0%Sold out
Madison Avenue Partners, LP0$00.00%−406,593−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−316,500−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−236,000−100.0%Sold out
Norges Bank0$00.00%−148,700−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−135,706−100.0%Sold out
HRT Financial LP0$00.00%−125,119−100.0%Sold out
Tekla Capital Management LLC0$00.00%−122,271−100.0%Sold out
Jefferies Financial Group Inc.0$00.00%−100,000−100.0%Sold out
Man Group plc0$00.00%−94,070−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−90,107−100.0%Sold out
PDT Partners, LLC0$00.00%−81,835−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−55,839−100.0%Sold out
AQR Capital Management LLC0$00.00%−40,970−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−28,970−100.0%Sold out
Ergoteles LLC0$00.00%−23,000−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−22,300−100.0%Sold out
Caxton Associates LP0$00.00%−21,853−100.0%Sold out
Squarepoint Ops LLC0$00.00%−21,770−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−14,318−100.0%Sold out
DuPont Capital Management Corp0$00.00%−13,127−100.0%Sold out
XTX Topco Ltd0$00.00%−12,942−100.0%Sold out
Alpine Global Management, LLC0$00.00%−10,279−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−10,198−100.0%Sold out
Acadian Asset Management LLC0$00.00%−9,199−100.0%Sold out
Quantbot Technologies LP0$00.00%−6,700−100.0%Sold out
Lazard Asset Management LLC0$00.00%−6,404−100.0%Sold out
Group One Trading, L.P.0$00.00%−1,307−100.0%Sold out
Sofos Investments, Inc.0$00.00%−11−100.0%Sold out
Rothschild & Co Asset Management US Inc.––––Not filed