Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2022
Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 140
- −9 vs. Q4 2021
- Shares held
- 50.6M
- +1.19M (+2.4%) vs. Q4 2021
- Total value
- $1.19B
- −$490.3M (−29.1%) vs. Q4 2021
- New holders
- 20
- 54 more added
- Sold out
- 29
- 47 more reduced
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 7,128,579 | $168.8M | 0.01% | +281,302+4.1% | Added |
| RTW Investments, LP | 4,794,499 | $113.5M | 2.35% | +2,194,677+84.4% | Added |
| BVF Inc | 4,183,219 | $99.1M | 3.96% | +531,460+14.6% | Added |
| State Street Corp | 3,256,808 | $77.1M | 0.00% | +685,238+26.6% | Added |
| BlackRock Inc. | 3,246,174 | $76.9M | 0.00% | −35,462−1.1% | Reduced |
| Point72 Asset Management, L.P. | 2,915,100 | $69.0M | 0.31% | +495,337+20.5% | Added |
| Johnson & Johnson | 2,449,183 | $58.0M | 10.96% | 00.0% | Unchanged |
| Vanguard Group Inc | 2,330,074 | $55.2M | 0.00% | −18,092−0.8% | Reduced |
| Morgan Stanley | 1,337,103 | $31.7M | 0.00% | +1,229,687+1,144.8% | Added |
| Farallon Capital Management, L.L.C. | 1,134,457 | $26.9M | 0.15% | −782,677−40.8% | Reduced |
| Dimensional Fund Advisors LP | 862,892 | $20.4M | 0.01% | −11,759−1.3% | Reduced |
| Geode Capital Management, LLC | 832,921 | $19.7M | 0.00% | +54,840+7.0% | Added |
| Deutsche Bank AG | 822,323 | $19.5M | 0.01% | −2,549−0.3% | Reduced |
| Obermeyer Wood Investment Counsel, LLLP | 801,625 | $19.0M | 1.14% | +12,683+1.6% | Added |
| Artal Group S.A. | 800,100 | $18.9M | 0.80% | −449,900−36.0% | Reduced |
| Tri Locum Partners LP | 769,250 | $18.2M | 7.12% | +455,321+145.0% | Added |
| Cowen and Company, LLC | 722,575 | $17.1M | 1.73% | +719,397+22,636.8% | Added |
| Adage Capital Partners GP, L.L.C. | 600,045 | $14.2M | 0.03% | +150,000+33.3% | Added |
| Woodline Partners LP | 588,694 | $13.9M | 0.23% | +95,707+19.4% | Added |
| Fairmount Funds Management LLC | 549,988 | $13.0M | 3.08% | +549,988 | New |
| Sofinnova Investments, Inc. | 547,441 | $13.0M | 1.09% | +65,184+13.5% | Added |
| Millennium Management LLC | 460,115 | $10.9M | 0.01% | +69,042+17.7% | Added |
| Northern Trust Corp | 435,078 | $10.3M | 0.00% | −20,333−4.5% | Reduced |
| Altium Capital Management LP | 386,000 | $9.14M | 3.19% | +40,000+11.6% | Added |
| EcoR1 Capital, LLC | 381,711 | $9.04M | 0.28% | −2,257,995−85.5% | Reduced |
| Rothschild & Co Asset Management US Inc. | 379,126 | $8.98M | 0.11% | −111,898−22.8% | Reduced |
| Goldman Sachs Group Inc | 346,359 | $8.20M | 0.00% | +222,730+180.2% | Added |
| Commodore Capital LP | 331,886 | $7.86M | 1.76% | −473,687−58.8% | Reduced |
| Charles Schwab Investment Management Inc | 325,259 | $7.70M | 0.00% | +8,080+2.5% | Added |
| Polar Capital Holdings Plc | 303,429 | $7.18M | 0.04% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 300,468 | $7.12M | 0.00% | −76,664−20.3% | Reduced |
| Affinity Asset Advisors, LLC | 300,000 | $7.10M | 2.82% | +58,881+24.4% | Added |
| Two Sigma Investments, LP | 288,518 | $6.83M | 0.02% | +260,418+926.8% | Added |
| Lord, Abbett & Co. LLC | 275,787 | $6.53M | 0.02% | +112,123+68.5% | Added |
| Sessa Capital IM, L.P. | 257,000 | $6.09M | 0.37% | +257,000 | New |
| Opaleye Management Inc. | 251,500 | $5.96M | 1.85% | −90,500−26.5% | Reduced |
| Bank of America Corp | 247,876 | $5.87M | 0.00% | +128,269+107.2% | Added |
| Two Sigma Advisers, LP | 214,700 | $5.08M | 0.01% | +175,900+453.4% | Added |
| Rafferty Asset Management, LLC | 208,094 | $4.93M | 0.03% | +42,322+25.5% | Added |
| Citadel Advisors LLC | 186,824 | $4.42M | 0.01% | +151,276+425.6% | Added |
| Russell Investments Group, Ltd. | 183,116 | $4.33M | 0.01% | +19,527+11.9% | Added |
| Boothbay Fund Management, LLC | 156,641 | $3.71M | 0.12% | +156,641 | New |
| Bank of New York Mellon Corp | 139,769 | $3.31M | 0.00% | +1,275+0.9% | Added |
| Twin Lakes Capital Management, LLC | 139,397 | $3.30M | 1.86% | +817+0.6% | Added |
| Allianz Asset Management GmbH | 132,734 | $3.14M | 0.00% | −2,059−1.5% | Reduced |
| SEI Investments Co | 130,718 | $3.10M | 0.01% | −1,595−1.2% | Reduced |
| Alliancebernstein L.P. | 126,463 | $3.00M | 0.00% | +80,563+175.5% | Added |
| UBS Group AG | 122,765 | $2.91M | 0.00% | +56,454+85.1% | Added |
| Tekla Capital Management LLC | 122,271 | $2.90M | 0.10% | +21,234+21.0% | Added |
| Silvercrest Asset Management Group LLC | 119,834 | $2.84M | 0.02% | +1,119+0.9% | Added |
| Swiss National Bank | 101,500 | $2.40M | 0.00% | +7,300+7.7% | Added |
| Nuveen Asset Management, LLC | 304,112 | $2.35M | 0.00% | +64,183+26.8% | Added |
| Kennedy Capital Management, Inc. | 97,265 | $2.30M | 0.05% | −8,129−7.7% | Reduced |
| HighVista Strategies LLC | 92,045 | $2.18M | 1.39% | +61,046+196.9% | Added |
| Candriam Luxembourg S.C.A. | 83,646 | $1.98M | 0.01% | 00.0% | Unchanged |
| J. Goldman & Co LP | 81,873 | $1.94M | 0.15% | −48,644−37.3% | Reduced |
| Voloridge Investment Management, LLC | 76,601 | $1.81M | 0.01% | −107,047−58.3% | Reduced |
| Caption Management, LLC | 70,000 | $1.66M | 0.11% | −122,702−63.7% | Reduced |
| JPMorgan Chase & Co | 69,183 | $1.64M | 0.00% | −367,270−84.1% | Reduced |
| Pura Vida Investments, LLC | 65,371 | $1.55M | 0.19% | +65,371 | New |
| Engineers Gate Manager LP | 56,763 | $1.34M | 0.05% | +56,763 | New |
| Industrial Alliance Investment Management Inc. | 56,695 | $1.34M | 0.03% | −18,540−24.6% | Reduced |
| California State Teachers Retirement System | 56,052 | $1.33M | 0.00% | −4,413−7.3% | Reduced |
| State of Wisconsin Investment Board | 53,500 | $1.27M | 0.00% | −11,100−17.2% | Reduced |
| Susquehanna International Group, LLP | 50,754 | $1.20M | 0.00% | −245,659−82.9% | Reduced |
| Amitell Capital Pte Ltd | 50,129 | $1.19M | 0.86% | +50,129 | New |
| Alps Advisors Inc | 49,760 | $1.18M | 0.01% | −5,472−9.9% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 48,977 | $1.16M | 0.01% | +10,673+27.9% | Added |
| Twinbeech Capital LP | 46,825 | $1.11M | 0.05% | +46,825 | New |
| Rhumbline Advisers | 46,426 | $1.10M | 0.00% | +2,457+5.6% | Added |
| Barclays PLC | 44,302 | $1.05M | 0.00% | −76,295−63.3% | Reduced |
| First Trust Advisors LP | 41,772 | $989.0K | 0.00% | +41,772 | New |
| Manufacturers Life Insurance Company, The | 40,375 | $961.3K | 0.00% | +17,553+76.9% | Added |
| Parametric Portfolio Associates LLC | 39,771 | $942.0K | 0.00% | +17,120+75.6% | Added |
| Birchview Capital, LP | 38,000 | $900.0K | 0.65% | 00.0% | Unchanged |
| Citigroup Inc | 35,656 | $844.0K | 0.00% | −102,095−74.1% | Reduced |
| Jump Financial, LLC | 35,000 | $829.0K | 0.04% | −2,100−5.7% | Reduced |
| Walleye Capital LLC | 33,390 | $791.0K | 0.02% | −64,608−65.9% | Reduced |
| New York State Common Retirement Fund | 33,206 | $786.0K | 0.00% | +45+0.1% | Added |
| SG Americas Securities, LLC | 32,959 | $780.0K | 0.01% | −5,591−14.5% | Reduced |
| Credit Suisse AG | 32,898 | $779.0K | 0.00% | +4,550+16.1% | Added |
| UBS Asset Management Americas Inc | 32,664 | $773.5K | 0.00% | 00.0% | Unchanged |
| Invesco Ltd. | 30,026 | $711.0K | 0.00% | +10,201+51.5% | Added |
| Cubist Systematic Strategies, LLC | 28,136 | $666.0K | 0.01% | +27,590+5,053.1% | Added |
| Allspring Global Investments Holdings, LLC | 27,306 | $646.0K | 0.00% | +1,935+7.6% | Added |
| Nisa Investment Advisors, LLC | 26,390 | $625.0K | 0.00% | −760−2.8% | Reduced |
| Wells Fargo & Company | 26,019 | $616.0K | 0.00% | −14,339−35.5% | Reduced |
| Algert Global LLC | 24,317 | $576.0K | 0.04% | +24,317 | New |
| MetLife Investment Management | 23,914 | $566.3K | 0.00% | +8,826+58.5% | Added |
| Occudo Quantitative Strategies LP | 23,360 | $553.0K | 0.05% | +23,360 | New |
| Prudential Financial Inc | 22,993 | $544.0K | 0.00% | −7,112−23.6% | Reduced |
| American International Group, Inc. | 22,210 | $526.0K | 0.00% | −1,562−6.6% | Reduced |
| Franklin Street Advisors Inc | 22,220 | $526.0K | 0.04% | 00.0% | Unchanged |
| King Wealth | 22,000 | $521.0K | 0.10% | 00.0% | Unchanged |
| Legal & General Group Plc | 21,594 | $511.0K | 0.00% | +330+1.6% | Added |
| Vontobel Holding Ltd. | 20,000 | $474.0K | 0.00% | 00.0% | Unchanged |
| Maven Securities LTD | 19,700 | $466.0K | 0.10% | +19,700 | New |
| Renaissance Technologies LLC | 19,467 | $461.0K | 0.00% | +19,467 | New |
| BNP Paribas Arbitrage, SA | 19,148 | $453.4K | 0.00% | −19,510−50.5% | Reduced |
| TD Asset Management Inc | 17,842 | $422.0K | 0.00% | −15,200−46.0% | Reduced |