Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2023
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 157
- +14 vs. Q3 2023
- Shares held
- 57.5M
- +792.3K (+1.4%) vs. Q3 2023
- Total value
- $1.32B
- +$372.5M (+39.4%) vs. Q3 2023
- New holders
- 33
- 40 more added
- Sold out
- 19
- 60 more reduced
1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BVF Inc | 5,744,848 | $131.7M | 3.30% | 00.0% | Unchanged |
| Farallon Capital Management, L.L.C. | 5,734,430 | $131.5M | 0.82% | +288,000+5.3% | Added |
| BlackRock Inc. | 5,543,902 | $127.1M | 0.00% | +314,477+6.0% | Added |
| RTW Investments, LP | 5,315,514 | $121.9M | 1.90% | −100,000−1.8% | Reduced |
| Vanguard Group Inc | 3,153,916 | $72.3M | 0.00% | −74,478−2.3% | Reduced |
| State Street Corp | 2,729,929 | $62.6M | 0.00% | −1,212,209−30.8% | Reduced |
| Point72 Asset Management, L.P. | 2,613,453 | $59.9M | 0.18% | +1,505,313+135.8% | Added |
| Johnson & Johnson | 2,449,183 | $56.2M | 1.28% | 00.0% | Unchanged |
| Kynam Capital Management, LP | 2,004,875 | $46.0M | 5.20% | +186,218+10.2% | Added |
| Adage Capital Partners GP, L.L.C. | 1,291,701 | $29.6M | 0.06% | +591,701+84.5% | Added |
| Jefferies Financial Group Inc. | 1,270,561 | $29.1M | 0.46% | +435,000+52.1% | Added |
| Geode Capital Management, LLC | 1,248,284 | $28.6M | 0.00% | +67,028+5.7% | Added |
| Morgan Stanley | 1,191,837 | $27.3M | 0.00% | +762,833+177.8% | Added |
| Deutsche Bank AG | 910,012 | $20.9M | 0.01% | +838,099+1,165.4% | Added |
| Price T Rowe Associates Inc | 823,740 | $18.9M | 0.00% | −8,253−1.0% | Reduced |
| Dimensional Fund Advisors LP | 816,537 | $18.7M | 0.01% | −124,737−13.3% | Reduced |
| 683 Capital Management, LLC | 715,000 | $16.4M | 1.64% | −17,784−2.4% | Reduced |
| Northern Trust Corp | 550,139 | $12.6M | 0.00% | −12,549−2.2% | Reduced |
| Eversept Partners, LP | 538,074 | $12.3M | 1.21% | +251,326+87.6% | Added |
| Candriam Luxembourg S.C.A. | 537,000 | $12.3M | 0.08% | −93,000−14.8% | Reduced |
| Goldman Sachs Group Inc | 515,220 | $11.8M | 0.00% | +48,017+10.3% | Added |
| StemPoint Capital LP | 513,681 | $11.8M | 3.17% | +513,681 | New |
| FMR LLC | 465,952 | $10.7M | 0.00% | −43,290−8.5% | Reduced |
| Sio Capital Management, LLC | 460,044 | $10.5M | 2.72% | +211,917+85.4% | Added |
| Charles Schwab Investment Management Inc | 455,321 | $10.4M | 0.00% | +16,219+3.7% | Added |
| Mangrove Partners | 439,314 | $10.1M | 0.87% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 411,046 | $9.43M | 0.00% | +178,756+77.0% | Added |
| Gratus Capital LLC | 397,571 | $9.12M | 0.52% | +104,702+35.8% | Added |
| Perceptive Advisors LLC | 383,260 | $8.79M | 0.20% | −671,013−63.6% | Reduced |
| Superstring Capital Management LP | 379,143 | $8.69M | 6.21% | +379,143 | New |
| Ikarian Capital, LLC | 319,000 | $7.31M | 2.00% | +319,000 | New |
| Nuveen Asset Management, LLC | 305,419 | $7.00M | 0.00% | −230,605−43.0% | Reduced |
| Kennedy Capital Management, Inc. | 304,790 | $6.99M | 0.15% | −14,744−4.6% | Reduced |
| UBS Asset Management Americas Inc | 289,079 | $6.63M | 0.00% | +218,020+306.8% | Added |
| Deep Track Capital, LP | 275,201 | $6.31M | 0.22% | +275,201 | New |
| Checkpoint Capital L.P. | 266,856 | $6.12M | 4.27% | +266,856 | New |
| Two Sigma Advisers, LP | 222,000 | $5.09M | 0.01% | −94,900−29.9% | Reduced |
| Renaissance Technologies LLC | 213,967 | $4.91M | 0.01% | −12,301−5.4% | Reduced |
| Bank of New York Mellon Corp | 203,177 | $4.66M | 0.00% | +1,733+0.9% | Added |
| ADAR1 Capital Management, LLC | 200,859 | $4.61M | 2.06% | +200,859 | New |
| Driehaus Capital Management LLC | 198,689 | $4.56M | 0.05% | +198,689 | New |
| Walleye Capital LLC | 185,426 | $4.25M | 0.06% | +51,610+38.6% | Added |
| Silvercrest Asset Management Group LLC | 180,496 | $4.14M | 0.03% | +340.0% | Added |
| Rafferty Asset Management, LLC | 167,795 | $3.85M | 0.02% | −182,486−52.1% | Reduced |
| Two Sigma Investments, LP | 158,843 | $3.64M | 0.01% | −177,465−52.8% | Reduced |
| Bank of America Corp | 153,409 | $3.52M | 0.00% | −85,629−35.8% | Reduced |
| UBS Group AG | 150,867 | $3.46M | 0.00% | +60,141+66.3% | Added |
| Millennium Management LLC | 149,163 | $3.42M | 0.00% | +149,163 | New |
| Barclays PLC | 148,974 | $3.42M | 0.00% | −27,863−15.8% | Reduced |
| Marshall Wace, LLP | 142,470 | $3.27M | 0.01% | +120,723+555.1% | Added |
| Jacobs Levy Equity Management, Inc | 129,011 | $2.96M | 0.01% | 00.0% | Unchanged |
| Ghost Tree Capital, LLC | 125,000 | $2.87M | 1.65% | −275,000−68.8% | Reduced |
| HSBC Holdings PLC | 119,334 | $2.74M | 0.00% | −434,971−78.5% | Reduced |
| Opaleye Management Inc. | 112,700 | $2.58M | 0.69% | +112,700 | New |
| Artia Global Partners LP | 112,340 | $2.58M | 1.02% | 00.0% | Unchanged |
| TD Asset Management Inc | 110,800 | $2.54M | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 109,683 | $2.52M | 0.00% | +52,438+91.6% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 107,542 | $2.47M | 0.01% | −31,952−22.9% | Reduced |
| UBS Oconnor LLC | 106,154 | $2.43M | 0.08% | −30,114−22.1% | Reduced |
| Great Lakes Advisors, LLC | 91,153 | $2.09M | 0.02% | −50,406−35.6% | Reduced |
| Swiss National Bank | 90,700 | $2.08M | 0.00% | −9,900−9.8% | Reduced |
| Schonfeld Strategic Advisors LLC | 89,113 | $2.04M | 0.02% | −64,985−42.2% | Reduced |
| Alliancebernstein L.P. | 85,400 | $1.96M | 0.00% | −1,872−2.1% | Reduced |
| Rhumbline Advisers | 83,292 | $1.91M | 0.00% | +483+0.6% | Added |
| Soleus Capital Management, L.P. | 83,000 | $1.90M | 0.21% | +83,000 | New |
| Boothbay Fund Management, LLC | 80,607 | $1.85M | 0.07% | +80,607 | New |
| Algert Global LLC | 75,760 | $1.74M | 0.07% | +2,930+4.0% | Added |
| HRT Financial LP | 73,126 | $1.68M | 0.01% | +73,126 | New |
| Jane Street Group, LLC | 72,931 | $1.67M | 0.00% | +34,425+89.4% | Added |
| Citigroup Inc | 72,703 | $1.67M | 0.00% | −75,125−50.8% | Reduced |
| BNP Paribas Arbitrage, SA | 71,898 | $1.65M | 0.00% | −72,066−50.1% | Reduced |
| Manufacturers Life Insurance Company, The | 68,432 | $1.57M | 0.00% | −5,691−7.7% | Reduced |
| Credit Suisse AG | 62,517 | $1.43M | 0.00% | +12,404+24.8% | Added |
| Moody Aldrich Partners LLC | 62,327 | $1.43M | 0.26% | −6,641−9.6% | Reduced |
| Readystate Asset Management LP | 57,206 | $1.31M | 0.08% | −127,141−69.0% | Reduced |
| Knott David M Jr | 52,368 | $1.20M | 0.46% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 50,503 | $1.16M | 0.00% | +50,503 | New |
| California State Teachers Retirement System | 50,392 | $1.16M | 0.00% | −2,688−5.1% | Reduced |
| Birchview Capital, LP | 48,000 | $1.10M | 0.86% | +10,000+26.3% | Added |
| Citadel Advisors LLC | 47,864 | $1.10M | 0.00% | −2,932−5.8% | Reduced |
| Invesco Ltd. | 45,763 | $1.05M | 0.00% | +4,862+11.9% | Added |
| Legal & General Group Plc | 45,289 | $1.04M | 0.00% | +524+1.2% | Added |
| Voya Investment Management LLC | 43,245 | $991.6K | 0.00% | +282+0.7% | Added |
| Alps Advisors Inc | 40,072 | $918.9K | 0.01% | −2,377−5.6% | Reduced |
| State of Wisconsin Investment Board | 39,799 | $912.6K | 0.00% | −21,682−35.3% | Reduced |
| American Century Companies Inc | 38,344 | $879.2K | 0.00% | +38,344 | New |
| SEI Investments Co | 37,229 | $853.7K | 0.00% | −2,987−7.4% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 34,046 | $780.7K | 0.04% | +2,380+7.5% | Added |
| Mirae Asset Global Investments Co., Ltd. | 31,759 | $728.2K | 0.00% | −5,463−14.7% | Reduced |
| Fox Run Management, L.L.C. | 31,275 | $717.1K | 0.18% | +31,275 | New |
| AlphaCentric Advisors LLC | 30,000 | $687.9K | 0.46% | −13,500−31.0% | Reduced |
| Bellevue Group AG | 30,000 | $687.9K | 0.01% | 00.0% | Unchanged |
| Tudor Investment Corp Et Al | 28,786 | $660.1K | 0.01% | +28,786 | New |
| MetLife Investment Management | 28,596 | $655.7K | 0.00% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 28,400 | $651.2K | 0.00% | 00.0% | Unchanged |
| American International Group, Inc. | 28,390 | $651.0K | 0.00% | −115−0.4% | Reduced |
| HighVista Strategies LLC | 28,359 | $650.3K | 0.24% | +28,359 | New |
| Profund Advisors LLC | 27,890 | $639.5K | 0.03% | −30,826−52.5% | Reduced |
| Twinbeech Capital LP | 24,161 | $554.0K | 0.01% | −123,185−83.6% | Reduced |
| New York State Common Retirement Fund | 23,103 | $529.8K | 0.00% | −98−0.4% | Reduced |