Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 137
- +5 vs. Q3 2022
- Shares held
- 48.9M
- +1.68M (+3.5%) vs. Q3 2022
- Total value
- $533.3M
- +$135.4M (+34.0%) vs. Q3 2022
- New holders
- 21
- 51 more added
- Sold out
- 16
- 43 more reduced
1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| State Street Corp | 3,792,926 | $41.4M | 0.00% | −883,756−18.9% | Reduced |
| BlackRock Inc. | 3,652,157 | $39.8M | 0.00% | +189,773+5.5% | Added |
| Farallon Capital Management, L.L.C. | 3,651,887 | $39.8M | 0.26% | 00.0% | Unchanged |
| RTW Investments, LP | 3,591,986 | $39.2M | 0.80% | −584,851−14.0% | Reduced |
| Vanguard Group Inc | 3,097,714 | $33.8M | 0.00% | +154,947+5.3% | Added |
| Johnson & Johnson | 2,449,183 | $26.7M | 7.77% | 00.0% | Unchanged |
| Morgan Stanley | 2,438,517 | $26.6M | 0.00% | +210,942+9.5% | Added |
| Bain Capital Life Sciences Investors, LLC | 2,364,410 | $25.8M | 2.88% | +103,838+4.6% | Added |
| Citadel Advisors LLC | 2,355,314 | $25.7M | 0.03% | +1,488,927+171.9% | Added |
| Marshall Wace, LLP | 1,454,446 | $15.9M | 0.04% | +639,720+78.5% | Added |
| Millennium Management LLC | 1,345,389 | $14.7M | 0.02% | +1,147,367+579.4% | Added |
| Dimensional Fund Advisors LP | 1,077,226 | $11.8M | 0.00% | +256,788+31.3% | Added |
| Braidwell LP | 927,800 | $10.1M | 0.34% | +927,800 | New |
| Deutsche Bank AG | 925,662 | $10.1M | 0.01% | +113,307+13.9% | Added |
| Geode Capital Management, LLC | 879,891 | $9.60M | 0.00% | +52,435+6.3% | Added |
| Deep Track Capital, LP | 871,493 | $9.51M | 0.41% | +871,493 | New |
| Adage Capital Partners GP, L.L.C. | 767,045 | $8.37M | 0.02% | −106,000−12.1% | Reduced |
| Goldman Sachs Group Inc | 616,724 | $6.73M | 0.00% | −140,355−18.5% | Reduced |
| Two Sigma Advisers, LP | 603,500 | $6.58M | 0.02% | +196,200+48.2% | Added |
| Walleye Capital LLC | 524,302 | $5.72M | 0.12% | +421,359+409.3% | Added |
| Kynam Capital Management, LP | 520,922 | $5.68M | 0.87% | +1,710+0.3% | Added |
| Woodline Partners LP | 512,140 | $5.59M | 0.08% | +512,140 | New |
| Two Sigma Investments, LP | 491,965 | $5.37M | 0.02% | +246,260+100.2% | Added |
| Sio Capital Management, LLC | 434,635 | $4.74M | 2.53% | +434,635 | New |
| Northern Trust Corp | 418,607 | $4.57M | 0.00% | +824+0.2% | Added |
| Madison Avenue Partners, LP | 406,593 | $4.44M | 0.79% | +406,593 | New |
| Nuveen Asset Management, LLC | 360,714 | $3.94M | 0.00% | +22,170+6.5% | Added |
| Kennedy Capital Management, Inc. | 350,133 | $3.82M | 0.11% | +251,046+253.4% | Added |
| Bank of America Corp | 344,947 | $3.76M | 0.00% | +34,898+11.3% | Added |
| Charles Schwab Investment Management Inc | 340,021 | $3.71M | 0.00% | +6,378+1.9% | Added |
| Point72 Asset Management, L.P. | 316,500 | $3.45M | 0.01% | −2,221,493−87.5% | Reduced |
| JPMorgan Chase & Co | 303,162 | $3.31M | 0.00% | +127,603+72.7% | Added |
| Rafferty Asset Management, LLC | 295,348 | $3.22M | 0.03% | −51,587−14.9% | Reduced |
| Jacobs Levy Equity Management, Inc | 284,115 | $3.10M | 0.02% | +29,775+11.7% | Added |
| Renaissance Technologies LLC | 258,867 | $2.82M | 0.00% | −140,900−35.2% | Reduced |
| Barclays PLC | 254,887 | $2.78M | 0.00% | +38,893+18.0% | Added |
| Silvercrest Asset Management Group LLC | 240,745 | $2.63M | 0.02% | −2,268−0.9% | Reduced |
| Soleus Capital Management, L.P. | 236,000 | $2.57M | 0.37% | +236,000 | New |
| UBS Group AG | 225,529 | $2.46M | 0.00% | +178,949+384.2% | Added |
| Gratus Capital LLC | 219,059 | $2.39M | 0.20% | +12,946+6.3% | Added |
| 683 Capital Management, LLC | 207,800 | $2.27M | 0.20% | +207,800 | New |
| Russell Investments Group, Ltd. | 198,969 | $2.17M | 0.00% | −31,878−13.8% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 194,704 | $2.12M | 0.01% | +3,511+1.8% | Added |
| D. E. Shaw & Co., Inc. | 188,036 | $2.05M | 0.00% | +44,961+31.4% | Added |
| Voloridge Investment Management, LLC | 167,369 | $1.83M | 0.01% | −259,024−60.7% | Reduced |
| Bank of New York Mellon Corp | 164,325 | $1.79M | 0.00% | +6,266+4.0% | Added |
| Rothschild & Co Asset Management US Inc. | 153,294 | $1.67M | 0.03% | −1,188−0.8% | Reduced |
| Norges Bank | 148,700 | $1.62M | 0.00% | +148,700 | New |
| Citigroup Inc | 148,068 | $1.62M | 0.00% | −167,126−53.0% | Reduced |
| Voya Investment Management LLC | 139,399 | $1.52M | 0.00% | −7,060−4.8% | Reduced |
| Qube Research & Technologies Ltd | 135,706 | $1.48M | 0.01% | +44,430+48.7% | Added |
| HRT Financial LP | 125,119 | $1.36M | 0.02% | −88,978−41.6% | Reduced |
| Tekla Capital Management LLC | 122,271 | $1.33M | 0.05% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 112,195 | $1.22M | 0.00% | +69,682+163.9% | Added |
| AXA S.A. | 107,700 | $1.18M | 0.00% | 00.0% | Unchanged |
| Thrivent Financial for Lutherans | 100,993 | $1.10M | 0.00% | 00.0% | Unchanged |
| Jefferies Financial Group Inc. | 100,000 | $1.09M | 0.02% | +100,000 | New |
| Man Group plc | 94,070 | $1.03M | 0.00% | +14,135+17.7% | Added |
| BNP Paribas Arbitrage, SA | 91,025 | $993.1K | 0.00% | −145,238−61.5% | Reduced |
| ExodusPoint Capital Management, LP | 90,107 | $983.0K | 0.02% | −18,769−17.2% | Reduced |
| Swiss National Bank | 88,900 | $969.9K | 0.00% | +2,400+2.8% | Added |
| Algert Global LLC | 84,172 | $918.3K | 0.05% | +13,240+18.7% | Added |
| PDT Partners, LLC | 81,835 | $892.8K | 0.14% | −44,203−35.1% | Reduced |
| Los Angeles Capital Management LLC | 76,990 | $840.0K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 71,153 | $776.0K | 0.00% | +636+0.9% | Added |
| FMR LLC | 68,526 | $747.6K | 0.00% | −2,740,282−97.6% | Reduced |
| Susquehanna International Group, LLP | 67,031 | $731.3K | 0.00% | −79,457−54.2% | Reduced |
| SG Americas Securities, LLC | 57,121 | $623.0K | 0.01% | −43,079−43.0% | Reduced |
| Jane Street Group, LLC | 55,891 | $609.8K | 0.00% | +45,602+443.2% | Added |
| Gsa Capital Partners LLP | 55,839 | $609.0K | 0.08% | +43,694+359.8% | Added |
| Alliancebernstein L.P. | 54,200 | $591.3K | 0.00% | +14,200+35.5% | Added |
| Cubist Systematic Strategies, LLC | 51,506 | $561.9K | 0.00% | +32,477+170.7% | Added |
| California State Teachers Retirement System | 50,702 | $553.2K | 0.00% | +1,135+2.3% | Added |
| Walleye Trading LLC | 49,509 | $540.1K | 0.01% | +49,509 | New |
| Federated Hermes, Inc. | 46,808 | $510.7K | 0.00% | +46,808 | New |
| Franklin Street Advisors Inc | 42,220 | $461.0K | 0.04% | 00.0% | Unchanged |
| AQR Capital Management LLC | 40,970 | $447.0K | 0.00% | −73,718−64.3% | Reduced |
| Caption Management, LLC | 40,000 | $436.4K | 0.07% | 00.0% | Unchanged |
| Vontobel Holding Ltd. | 40,000 | $436.4K | 0.00% | +10,000+33.3% | Added |
| Birchview Capital, LP | 38,000 | $415.0K | 0.29% | 00.0% | Unchanged |
| SEI Investments Co | 35,945 | $392.2K | 0.00% | −617−1.7% | Reduced |
| Alps Advisors Inc | 33,349 | $363.8K | 0.00% | +6,528+24.3% | Added |
| Invesco Ltd. | 31,552 | $344.2K | 0.00% | +2,828+9.8% | Added |
| Credit Suisse AG | 31,237 | $340.8K | 0.00% | −795−2.5% | Reduced |
| Fox Run Management, L.L.C. | 28,970 | $316.1K | 0.13% | −11,713−28.8% | Reduced |
| New York State Common Retirement Fund | 27,673 | $301.9K | 0.00% | −24−0.1% | Reduced |
| MetLife Investment Management | 23,914 | $260.9K | 0.00% | 00.0% | Unchanged |
| Ergoteles LLC | 23,000 | $250.9K | 0.01% | −6,530−22.1% | Reduced |
| Aquatic Capital Management LLC | 22,300 | $243.0K | 0.02% | +22,300 | New |
| American International Group, Inc. | 22,009 | $240.1K | 0.00% | +164+0.8% | Added |
| King Wealth | 22,000 | $240.0K | 0.06% | 00.0% | Unchanged |
| Caxton Associates LP | 21,853 | $238.4K | 0.02% | +21,853 | New |
| Squarepoint Ops LLC | 21,770 | $237.5K | 0.00% | −55,092−71.7% | Reduced |
| Allianz Asset Management GmbH | 21,500 | $234.6K | 0.00% | +21,500 | New |
| Mirae Asset Global Investments Co., Ltd. | 19,877 | $216.9K | 0.00% | +20+0.1% | Added |
| Manufacturers Life Insurance Company, The | 18,518 | $202.0K | 0.00% | −54−0.3% | Reduced |
| E Fund Management Co., Ltd. | 15,482 | $169.0K | 0.01% | −8,366−35.1% | Reduced |
| STRS Ohio | 15,300 | $166.0K | 0.00% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 15,188 | $165.7K | 0.01% | +15,188 | New |
| Public Employees Retirement System of Ohio | 15,014 | $164.0K | 0.00% | −3,408−18.5% | Reduced |