Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Protagonist Therapeutics, Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 137
- +5 vs. Q3 2022
- Shares held
- 48.9M
- +1.68M (+3.5%) vs. Q3 2022
- Total value
- $533.3M
- +$135.4M (+34.0%) vs. Q3 2022
- New holders
- 21
- 51 more added
- Sold out
- 16
- 43 more reduced
1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 10 | $0 | 0.00% | −1−9.1% | Reduced |
| Sofos Investments, Inc. | 11 | $197 | 0.00% | +11 | New |
| Wells Fargo & Company | 37 | $404 | 0.00% | −2,307−98.4% | Reduced |
| Daiwa Securities Group Inc. | 163 | $2.00K | 0.00% | 00.0% | Unchanged |
| Truvestments Capital LLC | 345 | $3.76K | 0.00% | 00.0% | Unchanged |
| Leonteq Securities AG | 470 | $5.13K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 500 | $5.46K | 0.00% | +40+8.7% | Added |
| Global Retirement Partners, LLC | 1,000 | $10.9K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 1,307 | $14.3K | 0.00% | −20,956−94.1% | Reduced |
| Tower Research Capital LLC (TRC) | 1,747 | $19.0K | 0.00% | −25,407−93.6% | Reduced |
| Great West Life Assurance Co | 1,982 | $22.0K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 2,049 | $22.0K | 0.00% | +49+2.5% | Added |
| Metropolitan Life Insurance Co | 2,921 | $31.9K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 3,501 | $40.2K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 5,543 | $60.0K | 0.00% | +4,732+583.5% | Added |
| Amalgamated Bank | 5,765 | $63.0K | 0.00% | 00.0% | Unchanged |
| Allspring Global Investments Holdings, LLC | 5,903 | $64.4K | 0.00% | −5,784−49.5% | Reduced |
| Lazard Asset Management LLC | 6,404 | $69.0K | 0.00% | 00.0% | Unchanged |
| Quantbot Technologies LP | 6,700 | $73.1K | 0.01% | +5,700+570.0% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 8,536 | $93.1K | 0.00% | +1,337+18.6% | Added |
| Acadian Asset Management LLC | 9,199 | $100.0K | 0.00% | −128,001−93.3% | Reduced |
| Occudo Quantitative Strategies LP | 10,198 | $111.3K | 0.01% | −10,689−51.2% | Reduced |
| Alpine Global Management, LLC | 10,279 | $112.0K | 0.04% | +10,279 | New |
| Arizona State Retirement System | 10,387 | $113.3K | 0.00% | +10,387 | New |
| Mariner, LLC | 10,649 | $116.0K | 0.00% | −2,458−18.8% | Reduced |
| American Century Companies Inc | 11,056 | $120.6K | 0.00% | +11,056 | New |
| Teacher Retirement System of Texas | 11,128 | $121.0K | 0.00% | −818−6.8% | Reduced |
| State Board of Administration of Florida Retirement System | 11,323 | $123.5K | 0.00% | +360+3.3% | Added |
| Principal Financial Group Inc | 11,738 | $128.1K | 0.00% | +1,389+13.4% | Added |
| XTX Topco Ltd | 12,942 | $141.2K | 0.03% | −25,882−66.7% | Reduced |
| DuPont Capital Management Corp | 13,127 | $143.2K | 0.01% | +13,127 | New |
| DekaBank Deutsche Girozentrale | 15,800 | $154.0K | 0.00% | 00.0% | Unchanged |
| Virtus ETF Advisers LLC | 14,235 | $155.3K | 0.08% | −20.0% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 14,318 | $156.2K | 0.02% | −7,077−33.1% | Reduced |
| Obermeyer Wood Investment Counsel, LLLP | 14,350 | $156.6K | 0.01% | −958−6.3% | Reduced |
| Legal & General Group Plc | 14,408 | $157.2K | 0.00% | +1,118+8.4% | Added |
| Franklin Resources Inc | 14,748 | $160.9K | 0.00% | +14,748 | New |
| Public Employees Retirement System of Ohio | 15,014 | $164.0K | 0.00% | −3,408−18.5% | Reduced |
| Engineers Gate Manager LP | 15,188 | $165.7K | 0.01% | +15,188 | New |
| STRS Ohio | 15,300 | $166.0K | 0.00% | 00.0% | Unchanged |
| E Fund Management Co., Ltd. | 15,482 | $169.0K | 0.01% | −8,366−35.1% | Reduced |
| Manufacturers Life Insurance Company, The | 18,518 | $202.0K | 0.00% | −54−0.3% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 19,877 | $216.9K | 0.00% | +20+0.1% | Added |
| Allianz Asset Management GmbH | 21,500 | $234.6K | 0.00% | +21,500 | New |
| Squarepoint Ops LLC | 21,770 | $237.5K | 0.00% | −55,092−71.7% | Reduced |
| Caxton Associates LP | 21,853 | $238.4K | 0.02% | +21,853 | New |
| King Wealth | 22,000 | $240.0K | 0.06% | 00.0% | Unchanged |
| American International Group, Inc. | 22,009 | $240.1K | 0.00% | +164+0.8% | Added |
| Aquatic Capital Management LLC | 22,300 | $243.0K | 0.02% | +22,300 | New |
| Ergoteles LLC | 23,000 | $250.9K | 0.01% | −6,530−22.1% | Reduced |
| MetLife Investment Management | 23,914 | $260.9K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 27,673 | $301.9K | 0.00% | −24−0.1% | Reduced |
| Fox Run Management, L.L.C. | 28,970 | $316.1K | 0.13% | −11,713−28.8% | Reduced |
| Credit Suisse AG | 31,237 | $340.8K | 0.00% | −795−2.5% | Reduced |
| Invesco Ltd. | 31,552 | $344.2K | 0.00% | +2,828+9.8% | Added |
| Alps Advisors Inc | 33,349 | $363.8K | 0.00% | +6,528+24.3% | Added |
| SEI Investments Co | 35,945 | $392.2K | 0.00% | −617−1.7% | Reduced |
| Birchview Capital, LP | 38,000 | $415.0K | 0.29% | 00.0% | Unchanged |
| Caption Management, LLC | 40,000 | $436.4K | 0.07% | 00.0% | Unchanged |
| Vontobel Holding Ltd. | 40,000 | $436.4K | 0.00% | +10,000+33.3% | Added |
| AQR Capital Management LLC | 40,970 | $447.0K | 0.00% | −73,718−64.3% | Reduced |
| Franklin Street Advisors Inc | 42,220 | $461.0K | 0.04% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 46,808 | $510.7K | 0.00% | +46,808 | New |
| Walleye Trading LLC | 49,509 | $540.1K | 0.01% | +49,509 | New |
| California State Teachers Retirement System | 50,702 | $553.2K | 0.00% | +1,135+2.3% | Added |
| Cubist Systematic Strategies, LLC | 51,506 | $561.9K | 0.00% | +32,477+170.7% | Added |
| Alliancebernstein L.P. | 54,200 | $591.3K | 0.00% | +14,200+35.5% | Added |
| Gsa Capital Partners LLP | 55,839 | $609.0K | 0.08% | +43,694+359.8% | Added |
| Jane Street Group, LLC | 55,891 | $609.8K | 0.00% | +45,602+443.2% | Added |
| SG Americas Securities, LLC | 57,121 | $623.0K | 0.01% | −43,079−43.0% | Reduced |
| Susquehanna International Group, LLP | 67,031 | $731.3K | 0.00% | −79,457−54.2% | Reduced |
| FMR LLC | 68,526 | $747.6K | 0.00% | −2,740,282−97.6% | Reduced |
| Rhumbline Advisers | 71,153 | $776.0K | 0.00% | +636+0.9% | Added |
| Los Angeles Capital Management LLC | 76,990 | $840.0K | 0.00% | 00.0% | Unchanged |
| PDT Partners, LLC | 81,835 | $892.8K | 0.14% | −44,203−35.1% | Reduced |
| Algert Global LLC | 84,172 | $918.3K | 0.05% | +13,240+18.7% | Added |
| Swiss National Bank | 88,900 | $969.9K | 0.00% | +2,400+2.8% | Added |
| ExodusPoint Capital Management, LP | 90,107 | $983.0K | 0.02% | −18,769−17.2% | Reduced |
| BNP Paribas Arbitrage, SA | 91,025 | $993.1K | 0.00% | −145,238−61.5% | Reduced |
| Man Group plc | 94,070 | $1.03M | 0.00% | +14,135+17.7% | Added |
| Jefferies Financial Group Inc. | 100,000 | $1.09M | 0.02% | +100,000 | New |
| Thrivent Financial for Lutherans | 100,993 | $1.10M | 0.00% | 00.0% | Unchanged |
| AXA S.A. | 107,700 | $1.18M | 0.00% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 112,195 | $1.22M | 0.00% | +69,682+163.9% | Added |
| Tekla Capital Management LLC | 122,271 | $1.33M | 0.05% | 00.0% | Unchanged |
| HRT Financial LP | 125,119 | $1.36M | 0.02% | −88,978−41.6% | Reduced |
| Qube Research & Technologies Ltd | 135,706 | $1.48M | 0.01% | +44,430+48.7% | Added |
| Voya Investment Management LLC | 139,399 | $1.52M | 0.00% | −7,060−4.8% | Reduced |
| Citigroup Inc | 148,068 | $1.62M | 0.00% | −167,126−53.0% | Reduced |
| Norges Bank | 148,700 | $1.62M | 0.00% | +148,700 | New |
| Rothschild & Co Asset Management US Inc. | 153,294 | $1.67M | 0.03% | −1,188−0.8% | Reduced |
| Bank of New York Mellon Corp | 164,325 | $1.79M | 0.00% | +6,266+4.0% | Added |
| Voloridge Investment Management, LLC | 167,369 | $1.83M | 0.01% | −259,024−60.7% | Reduced |
| D. E. Shaw & Co., Inc. | 188,036 | $2.05M | 0.00% | +44,961+31.4% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 194,704 | $2.12M | 0.01% | +3,511+1.8% | Added |
| Russell Investments Group, Ltd. | 198,969 | $2.17M | 0.00% | −31,878−13.8% | Reduced |
| 683 Capital Management, LLC | 207,800 | $2.27M | 0.20% | +207,800 | New |
| Gratus Capital LLC | 219,059 | $2.39M | 0.20% | +12,946+6.3% | Added |
| UBS Group AG | 225,529 | $2.46M | 0.00% | +178,949+384.2% | Added |
| Soleus Capital Management, L.P. | 236,000 | $2.57M | 0.37% | +236,000 | New |