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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2024

Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
240
+55 vs. Q2 2024
Shares held
61.8M
+8.87M (+16.8%) vs. Q2 2024
Total value
$2.78B
+$946.0M (+51.6%) vs. Q2 2024
New holders
79
77 more added
Sold out
24
64 more reduced

3 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 240 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ3 2024: $2.78B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2024.

Institutions holding PTGX in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.10,224,295$460.1M0.01%+10,224,295New
Farallon Capital Management, L.L.C.5,861,006$263.7M1.45%+20,233+0.3%Added
RTW Investments, LP5,426,112$244.2M3.53%+139,708+2.6%Added
Vanguard Group Inc4,216,081$189.7M0.00%+972,608+30.0%Added
State Street Corp3,183,542$143.3M0.01%+1,101,218+52.9%Added
Johnson & Johnson2,449,183$110.2M25.79%00.0%Unchanged
BVF Inc1,850,167$83.3M2.44%−1,469,123−44.3%Reduced
Jefferies Financial Group Inc.1,814,696$81.7M1.33%−225,865−11.1%Reduced
Pacer Advisors, Inc.1,734,090$78.0M0.17%+1,733,662+405,061.2%Added
Geode Capital Management, LLC1,374,697$61.9M0.01%+3,528+0.3%Added
Perceptive Advisors LLC1,374,563$61.9M1.33%+105,828+8.3%Added
Price T Rowe Associates Inc1,309,467$58.9M0.01%+99,925+8.3%Added
Adage Capital Partners GP, L.L.C.1,200,891$54.0M0.10%−800,451−40.0%Reduced
ADAR1 Capital Management, LLC981,295$44.2M7.40%−622,637−38.8%Reduced
Goldman Sachs Group Inc821,856$37.0M0.01%+231,095+39.1%Added
Invesco Ltd.653,152$29.4M0.01%+564,718+638.6%Added
Morgan Stanley628,623$28.3M0.00%+283,330+82.1%Added
Northern Trust Corp580,089$26.1M0.00%+71,630+14.1%Added
American Century Companies Inc574,775$25.9M0.02%+547,464+2,004.6%Added
Charles Schwab Investment Management Inc565,503$25.4M0.00%+39,850+7.6%Added
JPMorgan Chase & Co502,985$22.6M0.00%+126,397+33.6%Added
Woodline Partners LP466,518$21.0M0.18%−355,655−43.3%Reduced
Kynam Capital Management, LP456,369$20.5M1.59%−343,631−43.0%Reduced
FMR LLC454,196$20.4M0.00%+19,737+4.5%Added
Driehaus Capital Management LLC445,352$20.0M0.17%−111,483−20.0%Reduced
Eversept Partners, LP445,204$20.0M1.54%−60,632−12.0%Reduced
Mangrove Partners439,314$19.8M1.91%00.0%Unchanged
Colony Group, LLC426,661$19.2M0.06%+426,661New
683 Capital Management, LLC420,000$18.9M1.93%−184,449−30.5%Reduced
UBS Asset Management Americas Inc368,132$16.6M0.00%−1,823−0.5%Reduced
Bank of New York Mellon Corp356,333$16.0M0.00%+152,034+74.4%Added
Polar Capital Holdings Plc350,000$15.8M0.09%+350,000New
Cowen and Company, LLC340,974$15.3M0.53%−841,294−71.2%Reduced
Qube Research & Technologies Ltd322,989$14.5M0.03%−130,163−28.7%Reduced
Principal Financial Group Inc320,832$14.4M0.01%+310,804+3,099.4%Added
Marshall Wace, LLP315,373$14.2M0.02%−256,804−44.9%Reduced
Eagle Asset Management Inc294,280$13.6M0.07%−63,353−17.7%Reduced
Kennedy Capital Management, Inc.267,033$12.0M0.27%−23,049−7.9%Reduced
Checkpoint Capital L.P.240,000$10.8M5.36%−115,000−32.4%Reduced
Nuveen Asset Management, LLC232,074$10.4M0.00%−141,918−37.9%Reduced
Skandinaviska Enskilda Banken AB (publ)230,114$10.4M0.05%+211,200+1,116.6%Added
Dimensional Fund Advisors LP225,589$10.2M0.00%−390,583−63.4%Reduced
Point72 Asset Management, L.P.214,872$9.67M0.03%−694,862−76.4%Reduced
TD Asset Management Inc172,202$7.67M0.01%+23,900+16.1%Added
Rhumbline Advisers164,178$7.39M0.01%+79,203+93.2%Added
Candriam Luxembourg S.C.A.162,492$7.31M0.04%−111,326−40.7%Reduced
Arrowstreet Capital, Limited Partnership158,067$7.11M0.01%+158,067New
Bank of America Corp153,517$6.91M0.00%−146,964−48.9%Reduced
Legal & General Group Plc153,006$6.89M0.00%+99,720+187.1%Added
Silverarc Capital Management, LLC146,657$6.60M1.49%+146,657New
Renaissance Technologies LLC144,167$6.49M0.01%−153,300−51.5%Reduced
Ameriprise Financial Inc143,807$6.47M0.00%+143,807New
First Trust Advisors LP140,924$6.34M0.01%+9,114+6.9%Added
AQR Capital Management LLC137,171$6.17M0.01%+112,116+447.5%Added
Victory Capital Management Inc130,797$5.89M0.01%+123,647+1,729.3%Added
Jacobs Levy Equity Management, Inc128,654$5.79M0.02%−357−0.3%Reduced
Barclays PLC126,995$5.71M0.00%+87,755+223.6%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.125,898$5.67M0.01%+125,898New
Public Sector Pension Investment Board124,949$5.62M0.03%+124,949New
Artia Global Partners LP124,440$5.60M1.58%00.0%Unchanged
Segall Bryant & Hamill, LLC120,301$5.41M0.07%+1,739+1.5%Added
Deutsche Bank AG120,169$5.41M0.00%−788,179−86.8%Reduced
Moody Aldrich Partners LLC119,287$5.37M0.98%−14,928−11.1%Reduced
Manufacturers Life Insurance Company, The115,765$5.21M0.00%+1,359+1.2%Added
Algert Global LLC115,679$5.21M0.14%−36,400−23.9%Reduced
Voya Investment Management LLC113,852$5.12M0.01%+48,786+75.0%Added
Walleye Capital LLC105,335$4.74M0.05%+105,335New
Opaleye Management Inc.105,000$4.72M0.79%00.0%Unchanged
Allspring Global Investments Holdings, LLC103,842$4.67M0.01%+103,414+24,162.1%Added
Rafferty Asset Management, LLC89,876$4.04M0.01%+14,606+19.4%Added
HighVista Strategies LLC89,508$4.03M1.39%+68,279+321.6%Added
Swiss National Bank85,900$3.87M0.00%00.0%Unchanged
Silvercrest Asset Management Group LLC85,254$3.84M0.03%−105,914−55.4%Reduced
Franklin Resources Inc81,591$3.78M0.00%+45,674+127.2%Added
Alliancebernstein L.P.81,919$3.69M0.00%−13,250−13.9%Reduced
Northwestern Mutual Wealth Management Co78,894$3.55M0.00%−78,894−50.0%Reduced
UBS Group AG78,799$3.55M0.00%+11,818+17.6%Added
Citigroup Inc73,490$3.31M0.00%+52,475+249.7%Added
E Fund Management Co., Ltd.71,666$3.22M0.17%+71,666New
Great Lakes Advisors, LLC69,625$3.13M0.03%−23,854−25.5%Reduced
Weiss Asset Management LP62,463$2.81M0.07%+62,463New
Schonfeld Strategic Advisors LLC61,026$2.75M0.02%+11,962+24.4%Added
Prudential Financial Inc60,798$2.74M0.00%+60,798New
Great West Life Assurance Co56,536$2.54M0.00%+51,323+984.5%Added
Man Group plc55,831$2.51M0.01%+48,176+629.3%Added
Knott David M Jr52,368$2.36M0.94%00.0%Unchanged
Alps Advisors Inc52,032$2.34M0.02%+6,260+13.7%Added
Swedbank AB50,000$2.25M0.00%+50,000New
Birchview Capital, LP48,000$2.16M1.87%00.0%Unchanged
State of Wisconsin Investment Board47,160$2.12M0.01%−8,791−15.7%Reduced
Thrivent Financial for Lutherans46,257$2.08M0.00%+46,257New
Point72 Europe (London) LLP45,317$2.04M0.17%+45,317New
Jackson Creek Investment Advisors LLC44,685$2.01M0.60%+10,034+29.0%Added
California State Teachers Retirement System42,665$1.92M0.00%−1,130−2.6%Reduced
Susquehanna International Group, LLP40,357$1.82M0.00%−315,229−88.7%Reduced
Hennion & Walsh Asset Management, Inc.37,413$1.68M0.08%−467−1.2%Reduced
CWM Advisors, LLC36,514$1.64M0.17%+26,280+256.8%Added
Mirae Asset Global ETFs Holdings Ltd.35,505$1.60M0.00%+3,385+10.5%Added
SEI Investments Co35,078$1.58M0.00%−6,685−16.0%Reduced
MetLife Investment Management33,805$1.52M0.01%00.0%Unchanged