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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2024

Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
240
+55 vs. Q2 2024
Shares held
61.8M
+8.87M (+16.8%) vs. Q2 2024
Total value
$2.78B
+$946.0M (+51.6%) vs. Q2 2024
New holders
79
77 more added
Sold out
24
64 more reduced

3 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 240 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ3 2024: $2.78B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2024.

Institutions holding PTGX in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
State of Alaska, Department of Revenue33,615$1.51M0.02%+33,615New
Corebridge Financial, Inc.33,562$1.51M0.01%+2,122+6.7%Added
Quantedge Capital Pte Ltd32,983$1.48M0.44%+32,983New
Jane Street Group, LLC32,858$1.48M0.00%−136,453−80.6%Reduced
Wellington Management Group LLP30,079$1.35M0.00%+30,079New
Cavalier Investments, LLC29,956$1.35M0.41%+29,956New
Wells Fargo & Company29,373$1.32M0.00%−817−2.7%Reduced
Illinois Municipal Retirement Fund29,124$1.31M0.02%+29,124New
Louisiana State Employees Retirement System28,500$1.28M0.02%+28,500New
State of Tennessee, Treasury Department27,743$1.25M0.00%+27,743New
Ensign Peak Advisors, Inc27,036$1.22M0.00%00.0%Unchanged
D. E. Shaw & Co., Inc.26,825$1.21M0.00%+13,673+104.0%Added
Winton Group Ltd25,983$1.17M0.08%+25,983New
SG Americas Securities, LLC25,740$1.16M0.00%+14,789+135.0%Added
Gsa Capital Partners LLP25,095$1.13M0.09%+66+0.3%Added
AlphaCentric Advisors LLC25,000$1.13M0.84%00.0%Unchanged
New York State Teachers Retirement System24,592$1.11M0.00%+24,592New
Quest Partners LLC23,947$1.08M0.10%+21,516+885.1%Added
Financial Enhancement Group LLC41,818$1.06M0.21%+41,818New
Yousif Capital Management, LLC23,240$1.05M0.01%+23,240New
Trexquant Investment LP23,091$1.04M0.01%−57,523−71.4%Reduced
Los Angeles Capital Management LLC22,446$1.01M0.00%−8,381−27.2%Reduced
Caption Management, LLC22,100$994.5K0.11%+22,100New
Toroso Investments, LLC22,062$992.8K0.01%00.0%Unchanged
STRS Ohio21,500$967.5K0.00%−3,400−13.7%Reduced
Janus Henderson Group PLC21,454$965.0K0.00%00.0%Unchanged
Sierra Summit Advisors LLC21,167$952.5K0.22%+21,167New
Comerica Bank20,904$940.7K0.00%+20,634+7,642.2%Added
BNP Paribas Arbitrage, SA20,294$913.2K0.00%+16,597+448.9%Added
Teachers Retirement System of the State of Kentucky20,200$909.0K0.01%+20,200New
New York State Common Retirement Fund20,182$908.2K0.00%−2,900−12.6%Reduced
Profund Advisors LLC20,083$903.7K0.03%+5,554+38.2%Added
Maryland State Retirement & Pension System19,892$895.1K0.02%+19,892New
Allianz Asset Management GmbH19,300$868.5K0.00%+8,200+73.9%Added
Janney Montgomery Scott LLC19,249$866.0K0.00%+19,249New
Intech Investment Management LLC19,128$860.8K0.01%+19,128New
Squarepoint Ops LLC18,566$835.5K0.00%+8,743+89.0%Added
Amalgamated Bank17,324$780.0K0.01%+15,301+756.4%Added
State Board of Administration of Florida Retirement System16,303$733.6K0.00%00.0%Unchanged
Mariner, LLC15,979$719.0K0.00%+3,696+30.1%Added
DekaBank Deutsche Girozentrale15,800$709.0K0.00%00.0%Unchanged
ProShare Advisors LLC15,681$705.6K0.00%+4,411+39.1%Added
Moran Wealth Management, LLC15,030$676.4K0.02%+3,250+27.6%Added
Glenmede Trust Co NA14,981$674.1K0.00%−525−3.4%Reduced
XTX Topco Ltd14,801$666.0K0.05%+14,801New
Scientech Research LLC14,527$653.7K0.13%+14,527New
Cerity Partners LLC14,241$640.8K0.00%+3,005+26.7%Added
Sherbrooke Park Advisers LLC13,993$629.7K0.14%+3,188+29.5%Added
Oregon Public Employees Retirement Fund13,900$625.5K0.01%+13,900New
Tudor Investment Corp Et Al13,858$623.6K0.01%+13,858New
Royal Bank of Canada13,563$610.0K0.00%+3,341+32.7%Added
Raymond James & Associates13,455$605.5K0.00%+2,926+27.8%Added
PEAK6 Investments LLC13,303$598.6K0.03%00.0%Unchanged
Envestnet Asset Management Inc12,783$575.2K0.00%−776−5.7%Reduced
Arizona State Retirement System12,666$570.0K0.00%+430+3.5%Added
Commonwealth of Pennsylvania Public School Empls Retrmt Sys12,591$566.6K0.00%+12,591New
Bellevue Group AG12,346$555.6K0.01%−2,800−18.5%Reduced
Two Sigma Advisers, LP12,100$544.5K0.00%−104,500−89.6%Reduced
Franklin Street Advisors Inc11,400$513.0K0.03%−70−0.6%Reduced
Advantage Alpha Capital Partners LP11,336$510.1K0.12%+11,336New
China Universal Asset Management Co., Ltd.11,329$509.8K0.06%+4,438+64.4%Added
Teacher Retirement System of Texas11,032$496.0K0.00%+1,426+14.8%Added
HighTower Advisors, LLC10,887$487.0K0.00%−12,897−54.2%Reduced
MYDA Advisors LLC10,000$450.0K0.13%+10,000New
Zurcher Kantonalbank (Zurich Cantonalbank)9,828$442.3K0.00%−16−0.2%Reduced
Teza Capital Management LLC9,463$425.8K0.05%+9,463New
Mutual of America Capital Management LLC8,860$398.7K0.00%+8,860New
Nomura Holdings Inc8,159$367.2K0.00%+8,159New
Guggenheim Capital LLC7,898$355.4K0.00%+7,898New
US Bancorp7,866$354.0K0.00%−701−8.2%Reduced
Mackenzie Financial Corp7,774$349.8K0.00%+7,774New
Creative Planning7,504$337.7K0.00%+7,504New
Pictet Asset Management Holding SA7,298$328.4K0.00%+1,450+24.8%Added
Everence Capital Management Inc7,050$317.0K0.02%+7,050New
Bleakley Financial Group, LLC7,031$316.4K0.01%+7,031New
State of Wyoming7,000$315.0K0.04%+5,509+369.5%Added
Entropy Technologies, LP6,929$311.8K0.03%+6,929New
Captrust Financial Advisors6,126$275.7K0.00%−14−0.2%Reduced
Brinker Capital Investments, LLC6,114$275.1K0.00%−1,274−17.2%Reduced
Orion Portfolio Solutions, LLC6,114$275.1K0.00%−1,274−17.2%Reduced
King Wealth6,000$270.0K0.04%−6,000−50.0%Reduced
CenterBook Partners LP5,976$268.9K0.02%+5,976New
Bank of Montreal5,980$266.5K0.00%+5,980New
Ameritas Investment Partners, Inc.5,912$266.0K0.01%00.0%Unchanged
HSBC Holdings PLC5,869$262.3K0.00%−1,660−22.0%Reduced
Two Sigma Investments, LP5,711$257.0K0.00%−76,926−93.1%Reduced
Cornerstone Investment Partners, LLC5,421$243.9K0.01%+5,421New
Y-Intercept (Hong Kong) Ltd5,251$236.3K0.01%−42,876−89.1%Reduced
Palumbo Wealth Management LLC5,211$234.5K0.09%+5,211New
Kestra Advisory Services, LLC5,183$233.2K0.00%+5,183New
Citadel Advisors LLC5,030$226.3K0.00%+5,030New
AXA S.A.4,888$220.0K0.00%+4,888New
O'Shaughnessy Asset Management, LLC4,551$210.9K0.00%+4,551New
Nisa Investment Advisors, LLC2,838$127.7K0.00%+93+3.4%Added
Point72 Asia (Singapore) Pte. Ltd.2,699$121.5K0.02%−11,857−81.5%Reduced
Lazard Asset Management LLC2,697$121.0K0.00%−3,374−55.6%Reduced
Virtus ETF Advisers LLC2,680$120.6K0.06%+45+1.7%Added
Globeflex Capital L P2,627$118.2K0.01%+2,627New
Acadian Asset Management LLC2,387$106.0K0.00%+2,387New
Mirae Asset Global Investments Co., Ltd.2,130$94.9K0.00%+379+21.6%Added