Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2021
Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 132
- −6 vs. Q2 2021
- Shares held
- 46.4M
- +694.4K (+1.5%) vs. Q2 2021
- Total value
- $820.8M
- −$1.22B (−59.9%) vs. Q2 2021
- New holders
- 25
- 59 more added
- Sold out
- 31
- 34 more reduced
1 institution that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q3 2021
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 6,492,638 | $115.0M | 0.01% | −623,745−8.8% | Reduced |
| Point72 Asset Management, L.P. | 4,387,300 | $77.7M | 0.37% | +3,232,100+279.8% | Added |
| BVF Inc | 3,901,759 | $69.1M | 2.70% | +147,664+3.9% | Added |
| BlackRock Inc. | 3,199,496 | $56.7M | 0.00% | +158,955+5.2% | Added |
| Johnson & Johnson | 2,449,183 | $43.4M | 3.81% | +2,449,183 | New |
| Farallon Capital Management, L.L.C. | 2,392,000 | $42.4M | 0.23% | +62,320+2.7% | Added |
| Vanguard Group Inc | 2,353,786 | $41.7M | 0.00% | +65,752+2.9% | Added |
| State Street Corp | 2,013,979 | $35.7M | 0.00% | +559,359+38.5% | Added |
| RTW Investments, LP | 1,753,695 | $31.1M | 0.47% | −1,753,695−50.0% | Reduced |
| Artal Group S.A. | 1,500,000 | $26.6M | 0.65% | +1,500,000 | New |
| EcoR1 Capital, LLC | 1,443,800 | $25.6M | 0.90% | +1,443,800 | New |
| Deerfield Management Company, L.P. (Series C) | 1,394,000 | $24.7M | 0.48% | +31,210+2.3% | Added |
| Dimensional Fund Advisors LP | 875,732 | $15.5M | 0.00% | +84,716+10.7% | Added |
| Deutsche Bank AG | 823,290 | $14.6M | 0.01% | +1,568+0.2% | Added |
| Obermeyer Wood Investment Counsel, LLLP | 776,689 | $13.8M | 0.76% | +15,671+2.1% | Added |
| Geode Capital Management, LLC | 728,930 | $12.9M | 0.00% | +15,092+2.1% | Added |
| Voloridge Investment Management, LLC | 550,083 | $9.75M | 0.06% | +543,579+8,357.6% | Added |
| Millennium Management LLC | 522,871 | $9.27M | 0.01% | +507,431+3,286.5% | Added |
| Commodore Capital LP | 498,079 | $8.83M | 2.33% | +287,479+136.5% | Added |
| Price T Rowe Associates Inc | 491,641 | $8.71M | 0.00% | −494,613−50.2% | Reduced |
| Morgan Stanley | 474,315 | $8.40M | 0.00% | +404,485+579.2% | Added |
| Northern Trust Corp | 456,977 | $8.10M | 0.00% | +12,392+2.8% | Added |
| JPMorgan Chase & Co | 428,695 | $7.60M | 0.00% | −4,733−1.1% | Reduced |
| Goldman Sachs Group Inc | 423,195 | $7.50M | 0.00% | +31,252+8.0% | Added |
| Altium Capital Management LP | 346,000 | $6.13M | 1.64% | +63,555+22.5% | Added |
| Opaleye Management Inc. | 330,222 | $5.85M | 1.09% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 309,832 | $5.49M | 0.00% | +28,454+10.1% | Added |
| Adage Capital Partners GP, L.L.C. | 300,045 | $5.32M | 0.01% | −250,000−45.5% | Reduced |
| Sofinnova Investments, Inc. | 297,709 | $5.28M | 0.34% | −151,373−33.7% | Reduced |
| Susquehanna International Group, LLP | 267,383 | $4.74M | 0.01% | +246,050+1,153.4% | Added |
| Sphera Funds Management Ltd. | 260,379 | $4.61M | 0.46% | −42,586−14.1% | Reduced |
| Polar Capital Holdings Plc | 218,936 | $3.88M | 0.02% | +99,733+83.7% | Added |
| Rothschild & Co Asset Management US Inc. | 217,483 | $3.85M | 0.05% | −170,745−44.0% | Reduced |
| Two Sigma Advisers, LP | 145,300 | $2.58M | 0.01% | −110,775−43.3% | Reduced |
| Twin Lakes Capital Management, LLC | 139,287 | $2.47M | 1.45% | −4,153−2.9% | Reduced |
| Federated Hermes, Inc. | 131,282 | $2.33M | 0.00% | +69,267+111.7% | Added |
| Bank of New York Mellon Corp | 131,133 | $2.32M | 0.00% | −15,197−10.4% | Reduced |
| Citadel Advisors LLC | 118,704 | $2.10M | 0.00% | −284,504−70.6% | Reduced |
| D. E. Shaw & Co., Inc. | 115,913 | $2.05M | 0.00% | −132,322−53.3% | Reduced |
| Kennedy Capital Management, Inc. | 112,265 | $1.99M | 0.04% | +40,318+56.0% | Added |
| Caption Management, LLC | 110,000 | $1.95M | 0.13% | +110,000 | New |
| Jabodon PT Co | 90,656 | $1.61M | 0.67% | +90,656 | New |
| Sio Capital Management, LLC | 90,000 | $1.59M | 0.51% | +90,000 | New |
| Swiss National Bank | 87,400 | $1.55M | 0.00% | +600+0.7% | Added |
| Tekla Capital Management LLC | 86,237 | $1.53M | 0.05% | +86,237 | New |
| Candriam Luxembourg S.C.A. | 83,646 | $1.48M | 0.01% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 77,002 | $1.36M | 0.00% | +22,998+42.6% | Added |
| Silvercrest Asset Management Group LLC | 71,343 | $1.26M | 0.01% | −48,048−40.2% | Reduced |
| State of Wisconsin Investment Board | 71,200 | $1.26M | 0.00% | +9,600+15.6% | Added |
| Nuveen Asset Management, LLC | 163,086 | $1.26M | 0.00% | −3,239−1.9% | Reduced |
| UBS Group AG | 69,215 | $1.23M | 0.00% | +66,544+2,491.4% | Added |
| Rafferty Asset Management, LLC | 69,130 | $1.23M | 0.01% | +29,938+76.4% | Added |
| Wells Fargo & Company | 58,729 | $1.04M | 0.00% | +28,711+95.6% | Added |
| Jane Street Group, LLC | 57,854 | $1.02M | 0.00% | +57,854 | New |
| Bank of America Corp | 57,651 | $1.02M | 0.00% | −8,082−12.3% | Reduced |
| California State Teachers Retirement System | 56,508 | $1.00M | 0.00% | −495−0.9% | Reduced |
| State of New Jersey Common Pension Fund D | 54,589 | $967.0K | 0.00% | +54,589 | New |
| Citigroup Inc | 51,185 | $907.0K | 0.00% | −21,355−29.4% | Reduced |
| Allianz Asset Management GmbH | 49,171 | $871.0K | 0.00% | −25,089−33.8% | Reduced |
| TD Asset Management Inc | 47,042 | $834.0K | 0.00% | −21,800−31.7% | Reduced |
| SEI Investments Co | 46,175 | $818.0K | 0.00% | −60,359−56.7% | Reduced |
| Alliancebernstein L.P. | 45,900 | $813.0K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 42,695 | $757.0K | 0.00% | +1,883+4.6% | Added |
| AQR Capital Management LLC | 41,677 | $739.0K | 0.00% | +15,069+56.6% | Added |
| Cinctive Capital Management LP | 40,387 | $716.0K | 0.04% | +40,387 | New |
| Skandinaviska Enskilda Banken AB (publ) | 38,304 | $679.0K | 0.00% | +7,676+25.1% | Added |
| Birchview Capital, LP | 38,000 | $673.0K | 0.46% | +28,000+280.0% | Added |
| Barclays PLC | 36,997 | $656.0K | 0.00% | +29,592+399.6% | Added |
| Integral Health Asset Management, LLC | 35,000 | $620.0K | 0.18% | +35,000 | New |
| Panagora Asset Management Inc | 31,437 | $557.0K | 0.00% | −105,761−77.1% | Reduced |
| Prudential Financial Inc | 30,295 | $537.0K | 0.00% | +450+1.5% | Added |
| New York State Common Retirement Fund | 29,938 | $531.0K | 0.00% | −5,852−16.4% | Reduced |
| PDT Partners, LLC | 29,700 | $526.0K | 0.04% | +29,700 | New |
| HighVista Strategies LLC | 28,311 | $501.0K | 0.33% | +2,458+9.5% | Added |
| Credit Suisse AG | 27,695 | $491.0K | 0.00% | +240+0.9% | Added |
| UBS Asset Management Americas Inc | 27,598 | $489.0K | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 24,600 | $436.0K | 0.00% | −48,777−66.5% | Reduced |
| American International Group, Inc. | 24,483 | $434.0K | 0.00% | +1,318+5.7% | Added |
| Occudo Quantitative Strategies LP | 23,876 | $423.0K | 0.05% | +23,876 | New |
| Manufacturers Life Insurance Company, The | 23,581 | $418.0K | 0.00% | +556+2.4% | Added |
| Invesco Ltd. | 22,452 | $398.0K | 0.00% | +4,330+23.9% | Added |
| Franklin Street Advisors Inc | 22,220 | $394.0K | 0.03% | +1,970+9.7% | Added |
| King Wealth | 22,000 | $390.0K | 0.08% | 00.0% | Unchanged |
| Bank of Montreal | 21,805 | $385.0K | 0.00% | −42,475−66.1% | Reduced |
| HAP Trading, LLC | 20,909 | $371.0K | 0.03% | +20,909 | New |
| Harvest Investment Services, LLC | 20,907 | $370.0K | 0.15% | +20,907 | New |
| Legal & General Group Plc | 20,632 | $365.0K | 0.00% | +8,071+64.3% | Added |
| Parametric Portfolio Associates LLC | 20,434 | $362.0K | 0.00% | −50,966−71.4% | Reduced |
| Vontobel Holding Ltd. | 20,000 | $354.0K | 0.00% | +10,000+100.0% | Added |
| SG Americas Securities, LLC | 19,366 | $343.0K | 0.00% | +16,556+589.2% | Added |
| Belvedere Trading LLC | 11,185 | $337.0K | 0.09% | +11,185 | New |
| Martingale Asset Management L P | 17,408 | $310.0K | 0.00% | +9,100+109.5% | Added |
| Voya Investment Management LLC | 17,437 | $309.0K | 0.00% | +1,187+7.3% | Added |
| ProShare Advisors LLC | 15,892 | $282.0K | 0.00% | −2,729−14.7% | Reduced |
| MetLife Investment Management | 15,088 | $267.4K | 0.00% | 00.0% | Unchanged |
| DekaBank Deutsche Girozentrale | 14,000 | $246.0K | 0.00% | 00.0% | Unchanged |
| Bellwether Advisors, LLC | 13,630 | $241.0K | 0.08% | +13,630 | New |
| STRS Ohio | 13,200 | $233.0K | 0.00% | +4,400+50.0% | Added |
| Susquehanna Fundamental Investments, LLC | 13,015 | $231.0K | 0.00% | −21,605−62.4% | Reduced |
| Tower Research Capital LLC (TRC) | 12,133 | $215.0K | 0.01% | +10,087+493.0% | Added |