Skip to main content

Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2021

Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
132
−6 vs. Q2 2021
Shares held
46.4M
+694.4K (+1.5%) vs. Q2 2021
Total value
$820.8M
−$1.22B (−59.9%) vs. Q2 2021
New holders
25
59 more added
Sold out
31
34 more reduced

1 institution that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 132 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ3 2021: $820.8M
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2021.

Institutions holding PTGX in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
State of Wyoming26$00.00%−95−78.5%Reduced
Ellevest, Inc.6$00.00%+6New
Advisor Group Holdings, Inc.57$1.00K0.00%−173−75.2%Reduced
Signaturefd, LLC46$1.00K0.00%00.0%Unchanged
Captrust Financial Advisors43$1.00K0.00%+43New
Cutler Group LP100$1.00K0.00%+100New
Harbour Investments, Inc.126$2.00K0.00%+51+68.0%Added
Daiwa Securities Group Inc.163$3.00K0.00%+82+101.2%Added
TCI Wealth Advisors, Inc.146$3.00K0.00%+51+53.7%Added
US Bancorp264$4.00K0.00%−91−25.6%Reduced
Truvestments Capital LLC250$4.00K0.00%00.0%Unchanged
Macquarie Group Ltd307$5.00K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC450$8.00K0.00%00.0%Unchanged
Penserra Capital Management LLC1,090$19.0K0.00%+90+9.0%Added
Cubist Systematic Strategies, LLC1,117$20.0K0.00%−2,783−71.4%Reduced
Eagle Bay Advisors LLC1,240$22.0K0.01%+240+24.0%Added
Group One Trading, L.P.1,800$32.0K0.00%+1,800New
Great West Life Assurance Co1,982$35.0K0.00%00.0%Unchanged
O'Shaughnessy Asset Management, LLC2,162$38.0K0.00%−241−10.0%Reduced
Lindbrook Capital, LLC2,450$43.0K0.01%+2,000+444.4%Added
Zurcher Kantonalbank (Zurich Cantonalbank)2,429$43.0K0.00%+2,429New
Ameritas Investment Partners, Inc.3,241$57.0K0.00%00.0%Unchanged
Royal Bank of Canada4,785$85.0K0.00%+1,455+43.7%Added
Virtus ETF Advisers LLC5,170$92.0K0.04%−271−5.0%Reduced
Kessler Investment Group, LLC5,165$92.0K0.07%+5,165New
BNP Paribas Arbitrage, SA8,007$141.9K0.00%+6,406+400.1%Added
SG3 Management, LLC10,000$177.0K0.06%+10,000New
Walleye Capital LLC10,116$179.0K0.01%+10,116New
Arizona State Retirement System10,773$191.0K0.00%+74+0.7%Added
State Board of Administration of Florida Retirement System10,828$192.0K0.00%+380+3.6%Added
Bingham Osborn & Scarborough LLC11,640$206.0K0.01%00.0%Unchanged
Metropolitan Life Insurance Co11,747$208.2K0.00%+195+1.7%Added
Tower Research Capital LLC (TRC)12,133$215.0K0.01%+10,087+493.0%Added
Susquehanna Fundamental Investments, LLC13,015$231.0K0.00%−21,605−62.4%Reduced
STRS Ohio13,200$233.0K0.00%+4,400+50.0%Added
Bellwether Advisors, LLC13,630$241.0K0.08%+13,630New
DekaBank Deutsche Girozentrale14,000$246.0K0.00%00.0%Unchanged
MetLife Investment Management15,088$267.4K0.00%00.0%Unchanged
ProShare Advisors LLC15,892$282.0K0.00%−2,729−14.7%Reduced
Voya Investment Management LLC17,437$309.0K0.00%+1,187+7.3%Added
Martingale Asset Management L P17,408$310.0K0.00%+9,100+109.5%Added
Belvedere Trading LLC11,185$337.0K0.09%+11,185New
SG Americas Securities, LLC19,366$343.0K0.00%+16,556+589.2%Added
Vontobel Holding Ltd.20,000$354.0K0.00%+10,000+100.0%Added
Parametric Portfolio Associates LLC20,434$362.0K0.00%−50,966−71.4%Reduced
Legal & General Group Plc20,632$365.0K0.00%+8,071+64.3%Added
Harvest Investment Services, LLC20,907$370.0K0.15%+20,907New
HAP Trading, LLC20,909$371.0K0.03%+20,909New
Bank of Montreal21,805$385.0K0.00%−42,475−66.1%Reduced
King Wealth22,000$390.0K0.08%00.0%Unchanged
Franklin Street Advisors Inc22,220$394.0K0.03%+1,970+9.7%Added
Invesco Ltd.22,452$398.0K0.00%+4,330+23.9%Added
Manufacturers Life Insurance Company, The23,581$418.0K0.00%+556+2.4%Added
Occudo Quantitative Strategies LP23,876$423.0K0.05%+23,876New
American International Group, Inc.24,483$434.0K0.00%+1,318+5.7%Added
Two Sigma Investments, LP24,600$436.0K0.00%−48,777−66.5%Reduced
UBS Asset Management Americas Inc27,598$489.0K0.00%00.0%Unchanged
Credit Suisse AG27,695$491.0K0.00%+240+0.9%Added
HighVista Strategies LLC28,311$501.0K0.33%+2,458+9.5%Added
PDT Partners, LLC29,700$526.0K0.04%+29,700New
New York State Common Retirement Fund29,938$531.0K0.00%−5,852−16.4%Reduced
Prudential Financial Inc30,295$537.0K0.00%+450+1.5%Added
Panagora Asset Management Inc31,437$557.0K0.00%−105,761−77.1%Reduced
Integral Health Asset Management, LLC35,000$620.0K0.18%+35,000New
Barclays PLC36,997$656.0K0.00%+29,592+399.6%Added
Birchview Capital, LP38,000$673.0K0.46%+28,000+280.0%Added
Skandinaviska Enskilda Banken AB (publ)38,304$679.0K0.00%+7,676+25.1%Added
Cinctive Capital Management LP40,387$716.0K0.04%+40,387New
AQR Capital Management LLC41,677$739.0K0.00%+15,069+56.6%Added
Rhumbline Advisers42,695$757.0K0.00%+1,883+4.6%Added
Alliancebernstein L.P.45,900$813.0K0.00%00.0%Unchanged
SEI Investments Co46,175$818.0K0.00%−60,359−56.7%Reduced
TD Asset Management Inc47,042$834.0K0.00%−21,800−31.7%Reduced
Allianz Asset Management GmbH49,171$871.0K0.00%−25,089−33.8%Reduced
Citigroup Inc51,185$907.0K0.00%−21,355−29.4%Reduced
State of New Jersey Common Pension Fund D54,589$967.0K0.00%+54,589New
California State Teachers Retirement System56,508$1.00M0.00%−495−0.9%Reduced
Bank of America Corp57,651$1.02M0.00%−8,082−12.3%Reduced
Jane Street Group, LLC57,854$1.02M0.00%+57,854New
Wells Fargo & Company58,729$1.04M0.00%+28,711+95.6%Added
Rafferty Asset Management, LLC69,130$1.23M0.01%+29,938+76.4%Added
UBS Group AG69,215$1.23M0.00%+66,544+2,491.4%Added
Nuveen Asset Management, LLC163,086$1.26M0.00%−3,239−1.9%Reduced
State of Wisconsin Investment Board71,200$1.26M0.00%+9,600+15.6%Added
Silvercrest Asset Management Group LLC71,343$1.26M0.01%−48,048−40.2%Reduced
Russell Investments Group, Ltd.77,002$1.36M0.00%+22,998+42.6%Added
Candriam Luxembourg S.C.A.83,646$1.48M0.01%00.0%Unchanged
Tekla Capital Management LLC86,237$1.53M0.05%+86,237New
Swiss National Bank87,400$1.55M0.00%+600+0.7%Added
Sio Capital Management, LLC90,000$1.59M0.51%+90,000New
Jabodon PT Co90,656$1.61M0.67%+90,656New
Caption Management, LLC110,000$1.95M0.13%+110,000New
Kennedy Capital Management, Inc.112,265$1.99M0.04%+40,318+56.0%Added
D. E. Shaw & Co., Inc.115,913$2.05M0.00%−132,322−53.3%Reduced
Citadel Advisors LLC118,704$2.10M0.00%−284,504−70.6%Reduced
Bank of New York Mellon Corp131,133$2.32M0.00%−15,197−10.4%Reduced
Federated Hermes, Inc.131,282$2.33M0.00%+69,267+111.7%Added
Twin Lakes Capital Management, LLC139,287$2.47M1.45%−4,153−2.9%Reduced
Two Sigma Advisers, LP145,300$2.58M0.01%−110,775−43.3%Reduced
Rothschild & Co Asset Management US Inc.217,483$3.85M0.05%−170,745−44.0%Reduced