Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2022
Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 133
- +2 vs. Q2 2022
- Shares held
- 47.3M
- −6.02M (−11.3%) vs. Q2 2022
- Total value
- $398.9M
- −$23.2M (−5.5%) vs. Q2 2022
- New holders
- 28
- 41 more added
- Sold out
- 26
- 41 more reduced
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| State Street Corp | 4,676,682 | $39.4M | 0.00% | −2,099,587−31.0% | Reduced |
| RTW Investments, LP | 4,176,837 | $35.2M | 0.81% | −617,662−12.9% | Reduced |
| Farallon Capital Management, L.L.C. | 3,651,887 | $30.8M | 0.19% | −48,721−1.3% | Reduced |
| BlackRock Inc. | 3,462,384 | $29.2M | 0.00% | +7,468+0.2% | Added |
| Vanguard Group Inc | 2,942,767 | $24.8M | 0.00% | +208,002+7.6% | Added |
| FMR LLC | 2,808,808 | $23.7M | 0.00% | −682,198−19.5% | Reduced |
| Point72 Asset Management, L.P. | 2,537,993 | $21.4M | 0.09% | −1,518,207−37.4% | Reduced |
| Johnson & Johnson | 2,449,183 | $20.6M | 6.08% | 00.0% | Unchanged |
| Bain Capital Life Sciences Investors, LLC | 2,260,572 | $19.1M | 2.27% | 00.0% | Unchanged |
| Morgan Stanley | 2,227,575 | $18.8M | 0.00% | +451,123+25.4% | Added |
| Adage Capital Partners GP, L.L.C. | 873,045 | $7.36M | 0.02% | −127,000−12.7% | Reduced |
| Citadel Advisors LLC | 866,387 | $7.30M | 0.01% | +792,258+1,068.8% | Added |
| Geode Capital Management, LLC | 827,456 | $6.97M | 0.00% | +5,535+0.7% | Added |
| Dimensional Fund Advisors LP | 820,438 | $6.92M | 0.00% | −32,337−3.8% | Reduced |
| Marshall Wace, LLP | 814,726 | $6.87M | 0.02% | +350,669+75.6% | Added |
| Deutsche Bank AG | 812,355 | $6.85M | 0.00% | −5,477−0.7% | Reduced |
| Goldman Sachs Group Inc | 757,079 | $6.38M | 0.00% | +125,163+19.8% | Added |
| Kynam Capital Management, LP | 519,212 | $4.38M | 0.92% | +519,212 | New |
| Voloridge Investment Management, LLC | 426,393 | $3.59M | 0.02% | −170,094−28.5% | Reduced |
| Northern Trust Corp | 417,783 | $3.52M | 0.00% | −5,671−1.3% | Reduced |
| Two Sigma Advisers, LP | 407,300 | $3.43M | 0.01% | −111,100−21.4% | Reduced |
| Renaissance Technologies LLC | 399,767 | $3.37M | 0.00% | +76,900+23.8% | Added |
| Rafferty Asset Management, LLC | 346,935 | $2.92M | 0.03% | +32,703+10.4% | Added |
| Nuveen Asset Management, LLC | 338,544 | $2.85M | 0.00% | +572+0.2% | Added |
| Charles Schwab Investment Management Inc | 333,643 | $2.81M | 0.00% | +8,885+2.7% | Added |
| Citigroup Inc | 315,194 | $2.66M | 0.00% | −2,305−0.7% | Reduced |
| Bank of America Corp | 310,049 | $2.61M | 0.00% | +2,819+0.9% | Added |
| Jacobs Levy Equity Management, Inc | 254,340 | $2.14M | 0.02% | +254,340 | New |
| Two Sigma Investments, LP | 245,705 | $2.07M | 0.01% | −69,939−22.2% | Reduced |
| Silvercrest Asset Management Group LLC | 243,013 | $2.05M | 0.02% | +128,254+111.8% | Added |
| BNP Paribas Arbitrage, SA | 236,263 | $1.99M | 0.01% | +192,626+441.4% | Added |
| UBS Oconnor LLC | 232,820 | $1.96M | 0.02% | +13,000+5.9% | Added |
| Russell Investments Group, Ltd. | 230,847 | $1.94M | 0.00% | −58,715−20.3% | Reduced |
| Barclays PLC | 215,994 | $1.82M | 0.00% | +192,463+817.9% | Added |
| HRT Financial LP | 214,097 | $1.80M | 0.02% | +214,097 | New |
| Gratus Capital LLC | 206,113 | $1.74M | 0.19% | +206,113 | New |
| Millennium Management LLC | 198,022 | $1.67M | 0.00% | −891,506−81.8% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 191,193 | $1.61M | 0.01% | +191,193 | New |
| JPMorgan Chase & Co | 175,559 | $1.48M | 0.00% | +55,064+45.7% | Added |
| Bank of New York Mellon Corp | 158,059 | $1.33M | 0.00% | +15,988+11.3% | Added |
| Rothschild & Co Asset Management US Inc. | 154,482 | $1.30M | 0.02% | −212,635−57.9% | Reduced |
| Susquehanna International Group, LLP | 146,488 | $1.24M | 0.00% | +81,328+124.8% | Added |
| Voya Investment Management LLC | 146,459 | $1.23M | 0.00% | +129,091+743.3% | Added |
| D. E. Shaw & Co., Inc. | 143,075 | $1.21M | 0.00% | +143,075 | New |
| Acadian Asset Management LLC | 137,200 | $1.16M | 0.01% | +137,200 | New |
| PDT Partners, LLC | 126,038 | $1.06M | 0.16% | +37,460+42.3% | Added |
| Tekla Capital Management LLC | 122,271 | $1.03M | 0.04% | 00.0% | Unchanged |
| Jefferies Group LLC | 115,500 | $973.7K | 0.03% | +115,500 | New |
| AQR Capital Management LLC | 114,688 | $967.0K | 0.00% | +114,688 | New |
| ExodusPoint Capital Management, LP | 108,876 | $918.0K | 0.01% | −2,250−2.0% | Reduced |
| AXA S.A. | 107,700 | $907.9K | 0.00% | +107,700 | New |
| Walleye Capital LLC | 102,943 | $868.0K | 0.02% | −154,414−60.0% | Reduced |
| Thrivent Financial for Lutherans | 100,993 | $852.0K | 0.00% | +100,993 | New |
| SG Americas Securities, LLC | 100,200 | $845.0K | 0.01% | −52,833−34.5% | Reduced |
| Kennedy Capital Management, Inc. | 99,087 | $835.0K | 0.02% | −89−0.1% | Reduced |
| Qube Research & Technologies Ltd | 91,276 | $769.0K | 0.00% | +91,276 | New |
| Swiss National Bank | 86,500 | $729.0K | 0.00% | +2,200+2.6% | Added |
| Man Group plc | 79,935 | $674.0K | 0.00% | – | – |
| Los Angeles Capital Management LLC | 76,990 | $649.0K | 0.00% | +6,060+8.5% | Added |
| Squarepoint Ops LLC | 76,862 | $648.0K | 0.01% | +22,186+40.6% | Added |
| Algert Global LLC | 70,932 | $598.0K | 0.04% | −17,165−19.5% | Reduced |
| Rhumbline Advisers | 70,517 | $594.0K | 0.00% | +3,951+5.9% | Added |
| Graham Capital Management, L.P. | 53,443 | $450.0K | 0.02% | +53,443 | New |
| Jump Financial, LLC | 53,190 | $449.0K | 0.02% | +1,926+3.8% | Added |
| California State Teachers Retirement System | 49,567 | $418.0K | 0.00% | −371−0.7% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 48,977 | $413.0K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 46,580 | $393.0K | 0.00% | −82,407−63.9% | Reduced |
| State of Wisconsin Investment Board | 42,513 | $358.0K | 0.00% | −1,820−4.1% | Reduced |
| Franklin Street Advisors Inc | 42,220 | $356.0K | 0.04% | 00.0% | Unchanged |
| Fox Run Management, L.L.C. | 40,683 | $343.0K | 0.13% | +40,683 | New |
| Alliancebernstein L.P. | 40,000 | $337.0K | 0.00% | −6,000−13.0% | Reduced |
| Caption Management, LLC | 40,000 | $337.0K | 0.06% | +29,600+284.6% | Added |
| XTX Topco Ltd | 38,824 | $327.0K | 0.08% | +26,201+207.6% | Added |
| Birchview Capital, LP | 38,000 | $320.0K | 0.23% | 00.0% | Unchanged |
| SEI Investments Co | 36,562 | $308.0K | 0.00% | −84,443−69.8% | Reduced |
| Dynamic Technology Lab Private Ltd | 33,498 | $282.0K | 0.03% | +16,172+93.3% | Added |
| Credit Suisse AG | 32,032 | $270.0K | 0.00% | +217+0.7% | Added |
| Schonfeld Strategic Advisors LLC | 31,814 | $268.0K | 0.00% | −16,218−33.8% | Reduced |
| Vontobel Holding Ltd. | 30,000 | $253.0K | 0.00% | +10,000+50.0% | Added |
| Ergoteles LLC | 29,530 | $249.0K | 0.01% | +29,530 | New |
| Invesco Ltd. | 28,724 | $242.0K | 0.00% | −779−2.6% | Reduced |
| New York State Common Retirement Fund | 27,697 | $233.0K | 0.00% | +5,397+24.2% | Added |
| UBS Asset Management Americas Inc | 27,275 | $229.9K | 0.00% | −5,389−16.5% | Reduced |
| Tower Research Capital LLC (TRC) | 27,154 | $229.0K | 0.00% | −23,569−46.5% | Reduced |
| Alps Advisors Inc | 26,821 | $226.0K | 0.00% | −2,048−7.1% | Reduced |
| Tudor Investment Corp Et Al | 24,332 | $205.0K | 0.01% | +24,332 | New |
| MetLife Investment Management | 23,914 | $201.6K | 0.00% | 00.0% | Unchanged |
| E Fund Management Co., Ltd. | 23,848 | $201.0K | 0.02% | −12,185−33.8% | Reduced |
| Trexquant Investment LP | 22,421 | $189.0K | 0.01% | +22,421 | New |
| Group One Trading, L.P. | 22,263 | $188.0K | 0.01% | −21,651−49.3% | Reduced |
| King Wealth | 22,000 | $185.0K | 0.05% | 00.0% | Unchanged |
| American International Group, Inc. | 21,845 | $184.0K | 0.00% | +308+1.4% | Added |
| Y-Intercept (Hong Kong) Ltd | 21,395 | $180.4K | 0.02% | +21,395 | New |
| Occudo Quantitative Strategies LP | 20,887 | $176.0K | 0.01% | −117,508−84.9% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 19,857 | $167.0K | 0.00% | +5,934+42.6% | Added |
| Cubist Systematic Strategies, LLC | 19,029 | $160.0K | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 18,572 | $156.6K | 0.00% | −816−4.2% | Reduced |
| Public Employees Retirement System of Ohio | 18,422 | $155.0K | 0.00% | +18,422 | New |
| DekaBank Deutsche Girozentrale | 15,800 | $131.0K | 0.00% | 00.0% | Unchanged |
| Obermeyer Wood Investment Counsel, LLLP | 15,308 | $129.0K | 0.01% | +34+0.2% | Added |