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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2022

Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
133
+2 vs. Q2 2022
Shares held
47.3M
−6.02M (−11.3%) vs. Q2 2022
Total value
$398.9M
−$23.2M (−5.5%) vs. Q2 2022
New holders
28
41 more added
Sold out
26
41 more reduced

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 133 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ3 2022: $398.9M
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2022.

Institutions holding PTGX in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
STRS Ohio15,300$128.0K0.00%00.0%Unchanged
Virtus ETF Advisers LLC14,237$120.0K0.05%+108+0.8%Added
Legal & General Group Plc13,290$112.0K0.00%−4,836−26.7%Reduced
Mariner, LLC13,107$110.0K0.00%+13,107New
Ensign Peak Advisors, Inc12,270$103.0K0.00%+1,590+14.9%Added
Gsa Capital Partners LLP12,145$102.0K0.01%+12,145New
Bridgefront Capital, LLC12,084$102.0K0.10%+12,084New
Teacher Retirement System of Texas11,946$101.0K0.00%+11,946New
Allspring Global Investments Holdings, LLC11,687$98.0K0.00%+1,375+13.3%Added
State Board of Administration of Florida Retirement System10,963$92.0K0.00%00.0%Unchanged
Jane Street Group, LLC10,289$87.0K0.00%−27,667−72.9%Reduced
Principal Financial Group Inc10,349$87.0K0.00%+10,349New
Zurcher Kantonalbank (Zurich Cantonalbank)7,199$61.0K0.00%00.0%Unchanged
Lazard Asset Management LLC6,404$53.0K0.00%00.0%Unchanged
Amalgamated Bank5,765$49.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.3,501$29.0K0.00%00.0%Unchanged
Metropolitan Life Insurance Co2,921$24.6K0.00%00.0%Unchanged
Wells Fargo & Company2,344$19.0K0.00%−3,281−58.3%Reduced
Great West Life Assurance Co1,982$17.0K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC2,000$16.0K0.00%00.0%Unchanged
Dark Forest Capital Management LP1,582$13.0K0.00%+1,057+201.3%Added
US Bancorp1,112$9.00K0.00%+1,112New
Quantbot Technologies LP1,000$8.00K0.00%−8,658−89.6%Reduced
Global Retirement Partners, LLC1,000$8.00K0.00%+1,000New
Royal Bank of Canada811$7.00K0.00%+301+59.0%Added
Simplex Trading, LLC755$6.00K0.00%−8,882−92.2%Reduced
China Universal Asset Management Co., Ltd.460$4.00K0.00%+460New
Leonteq Securities AG470$3.96K0.00%00.0%Unchanged
Truvestments Capital LLC345$3.00K0.00%00.0%Unchanged
Macquarie Group Ltd0$3.00K0.00%−307−100.0%Reduced
TCI Wealth Advisors, Inc.387$3.00K0.00%+387New
Daiwa Securities Group Inc.163$1.00K0.00%00.0%Unchanged
Covestor Ltd11$00.00%+2+22.2%Added
BVF Inc0$00.00%−1,106,838−100.0%Sold out
Cowen and Company, LLC0$00.00%−1,065,724−100.0%Sold out
Finepoint Capital LP0$00.00%−735,126−100.0%Sold out
Woodline Partners LP0$00.00%−388,637−100.0%Sold out
Caas Capital Management LP0$00.00%−320,426−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−164,075−100.0%Sold out
Capital Fund Management S.A.0$00.00%−116,807−100.0%Sold out
Caxton Associates LP0$00.00%−61,370−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−57,923−100.0%Sold out
First Manhattan Co0$00.00%−55,800−100.0%Sold out
Amitell Capital Pte Ltd0$00.00%−50,129−100.0%Sold out
HighVista Strategies LLC0$00.00%−46,459−100.0%Sold out
Twinbeech Capital LP0$00.00%−20,317−100.0%Sold out
DuPont Capital Management Corp0$00.00%−16,499−100.0%Sold out
First Trust Advisors LP0$00.00%−14,328−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−12,540−100.0%Sold out
Delphia (USA) Inc.0$00.00%−11,845−100.0%Sold out
Cerity Partners LLC0$00.00%−11,640−100.0%Sold out
Engineers Gate Manager LP0$00.00%−11,383−100.0%Sold out
Quantamental Technologies LLC0$00.00%−11,170−100.0%Sold out
Corton Capital Inc.0$00.00%−10,836−100.0%Sold out
Atom Investors LP0$00.00%−10,338−100.0%Sold out
Eagle Bay Advisors LLC0$00.00%−1,000−100.0%Sold out
Lindbrook Capital, LLC0$00.00%−26−100.0%Sold out
International Biotechnology Trust PLC0$00.00%−128−100.0%Sold out
Federated Hermes, Inc.0$00.00%−28−100.0%Sold out