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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q3 2022

Institutional positions in Protagonist Therapeutics, Inc as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
133
+2 vs. Q2 2022
Shares held
47.3M
−6.02M (−11.3%) vs. Q2 2022
Total value
$398.9M
−$23.2M (−5.5%) vs. Q2 2022
New holders
28
41 more added
Sold out
26
41 more reduced

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 133 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ3 2022: $398.9M
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q2 2022.

Institutions holding PTGX in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd11$00.00%+2+22.2%Added
Daiwa Securities Group Inc.163$1.00K0.00%00.0%Unchanged
Truvestments Capital LLC345$3.00K0.00%00.0%Unchanged
Macquarie Group Ltd0$3.00K0.00%−307−100.0%Reduced
TCI Wealth Advisors, Inc.387$3.00K0.00%+387New
Leonteq Securities AG470$3.96K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.460$4.00K0.00%+460New
Simplex Trading, LLC755$6.00K0.00%−8,882−92.2%Reduced
Royal Bank of Canada811$7.00K0.00%+301+59.0%Added
Quantbot Technologies LP1,000$8.00K0.00%−8,658−89.6%Reduced
Global Retirement Partners, LLC1,000$8.00K0.00%+1,000New
US Bancorp1,112$9.00K0.00%+1,112New
Dark Forest Capital Management LP1,582$13.0K0.00%+1,057+201.3%Added
Nisa Investment Advisors, LLC2,000$16.0K0.00%00.0%Unchanged
Great West Life Assurance Co1,982$17.0K0.00%00.0%Unchanged
Wells Fargo & Company2,344$19.0K0.00%−3,281−58.3%Reduced
Metropolitan Life Insurance Co2,921$24.6K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.3,501$29.0K0.00%00.0%Unchanged
Amalgamated Bank5,765$49.0K0.00%00.0%Unchanged
Lazard Asset Management LLC6,404$53.0K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)7,199$61.0K0.00%00.0%Unchanged
Jane Street Group, LLC10,289$87.0K0.00%−27,667−72.9%Reduced
Principal Financial Group Inc10,349$87.0K0.00%+10,349New
State Board of Administration of Florida Retirement System10,963$92.0K0.00%00.0%Unchanged
Allspring Global Investments Holdings, LLC11,687$98.0K0.00%+1,375+13.3%Added
Teacher Retirement System of Texas11,946$101.0K0.00%+11,946New
Gsa Capital Partners LLP12,145$102.0K0.01%+12,145New
Bridgefront Capital, LLC12,084$102.0K0.10%+12,084New
Ensign Peak Advisors, Inc12,270$103.0K0.00%+1,590+14.9%Added
Mariner, LLC13,107$110.0K0.00%+13,107New
Legal & General Group Plc13,290$112.0K0.00%−4,836−26.7%Reduced
Virtus ETF Advisers LLC14,237$120.0K0.05%+108+0.8%Added
STRS Ohio15,300$128.0K0.00%00.0%Unchanged
Obermeyer Wood Investment Counsel, LLLP15,308$129.0K0.01%+34+0.2%Added
DekaBank Deutsche Girozentrale15,800$131.0K0.00%00.0%Unchanged
Public Employees Retirement System of Ohio18,422$155.0K0.00%+18,422New
Manufacturers Life Insurance Company, The18,572$156.6K0.00%−816−4.2%Reduced
Cubist Systematic Strategies, LLC19,029$160.0K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.19,857$167.0K0.00%+5,934+42.6%Added
Occudo Quantitative Strategies LP20,887$176.0K0.01%−117,508−84.9%Reduced
Y-Intercept (Hong Kong) Ltd21,395$180.4K0.02%+21,395New
American International Group, Inc.21,845$184.0K0.00%+308+1.4%Added
King Wealth22,000$185.0K0.05%00.0%Unchanged
Group One Trading, L.P.22,263$188.0K0.01%−21,651−49.3%Reduced
Trexquant Investment LP22,421$189.0K0.01%+22,421New
E Fund Management Co., Ltd.23,848$201.0K0.02%−12,185−33.8%Reduced
MetLife Investment Management23,914$201.6K0.00%00.0%Unchanged
Tudor Investment Corp Et Al24,332$205.0K0.01%+24,332New
Alps Advisors Inc26,821$226.0K0.00%−2,048−7.1%Reduced
Tower Research Capital LLC (TRC)27,154$229.0K0.00%−23,569−46.5%Reduced
UBS Asset Management Americas Inc27,275$229.9K0.00%−5,389−16.5%Reduced
New York State Common Retirement Fund27,697$233.0K0.00%+5,397+24.2%Added
Invesco Ltd.28,724$242.0K0.00%−779−2.6%Reduced
Ergoteles LLC29,530$249.0K0.01%+29,530New
Vontobel Holding Ltd.30,000$253.0K0.00%+10,000+50.0%Added
Schonfeld Strategic Advisors LLC31,814$268.0K0.00%−16,218−33.8%Reduced
Credit Suisse AG32,032$270.0K0.00%+217+0.7%Added
Dynamic Technology Lab Private Ltd33,498$282.0K0.03%+16,172+93.3%Added
SEI Investments Co36,562$308.0K0.00%−84,443−69.8%Reduced
Birchview Capital, LP38,000$320.0K0.23%00.0%Unchanged
XTX Topco Ltd38,824$327.0K0.08%+26,201+207.6%Added
Alliancebernstein L.P.40,000$337.0K0.00%−6,000−13.0%Reduced
Caption Management, LLC40,000$337.0K0.06%+29,600+284.6%Added
Fox Run Management, L.L.C.40,683$343.0K0.13%+40,683New
Franklin Street Advisors Inc42,220$356.0K0.04%00.0%Unchanged
State of Wisconsin Investment Board42,513$358.0K0.00%−1,820−4.1%Reduced
UBS Group AG46,580$393.0K0.00%−82,407−63.9%Reduced
Skandinaviska Enskilda Banken AB (publ)48,977$413.0K0.00%00.0%Unchanged
California State Teachers Retirement System49,567$418.0K0.00%−371−0.7%Reduced
Jump Financial, LLC53,190$449.0K0.02%+1,926+3.8%Added
Graham Capital Management, L.P.53,443$450.0K0.02%+53,443New
Rhumbline Advisers70,517$594.0K0.00%+3,951+5.9%Added
Algert Global LLC70,932$598.0K0.04%−17,165−19.5%Reduced
Squarepoint Ops LLC76,862$648.0K0.01%+22,186+40.6%Added
Los Angeles Capital Management LLC76,990$649.0K0.00%+6,060+8.5%Added
Man Group plc79,935$674.0K0.00%––
Swiss National Bank86,500$729.0K0.00%+2,200+2.6%Added
Qube Research & Technologies Ltd91,276$769.0K0.00%+91,276New
Kennedy Capital Management, Inc.99,087$835.0K0.02%−89−0.1%Reduced
SG Americas Securities, LLC100,200$845.0K0.01%−52,833−34.5%Reduced
Thrivent Financial for Lutherans100,993$852.0K0.00%+100,993New
Walleye Capital LLC102,943$868.0K0.02%−154,414−60.0%Reduced
AXA S.A.107,700$907.9K0.00%+107,700New
ExodusPoint Capital Management, LP108,876$918.0K0.01%−2,250−2.0%Reduced
AQR Capital Management LLC114,688$967.0K0.00%+114,688New
Jefferies Group LLC115,500$973.7K0.03%+115,500New
Tekla Capital Management LLC122,271$1.03M0.04%00.0%Unchanged
PDT Partners, LLC126,038$1.06M0.16%+37,460+42.3%Added
Acadian Asset Management LLC137,200$1.16M0.01%+137,200New
D. E. Shaw & Co., Inc.143,075$1.21M0.00%+143,075New
Voya Investment Management LLC146,459$1.23M0.00%+129,091+743.3%Added
Susquehanna International Group, LLP146,488$1.24M0.00%+81,328+124.8%Added
Rothschild & Co Asset Management US Inc.154,482$1.30M0.02%−212,635−57.9%Reduced
Bank of New York Mellon Corp158,059$1.33M0.00%+15,988+11.3%Added
JPMorgan Chase & Co175,559$1.48M0.00%+55,064+45.7%Added
Connor, Clark & Lunn Investment Management Ltd.191,193$1.61M0.01%+191,193New
Millennium Management LLC198,022$1.67M0.00%−891,506−81.8%Reduced
Gratus Capital LLC206,113$1.74M0.19%+206,113New
HRT Financial LP214,097$1.80M0.02%+214,097New
Barclays PLC215,994$1.82M0.00%+192,463+817.9%Added