Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2022
Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 131
- −7 vs. Q1 2022
- Shares held
- 53.3M
- +2.76M (+5.5%) vs. Q1 2022
- Total value
- $422.1M
- −$771.0M (−64.6%) vs. Q1 2022
- New holders
- 28
- 44 more added
- Sold out
- 35
- 38 more reduced
2 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| State Street Corp | 6,776,269 | $53.6M | 0.00% | +3,519,461+108.1% | Added |
| RTW Investments, LP | 4,794,499 | $37.9M | 0.98% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 4,056,200 | $32.1M | 0.15% | +1,141,100+39.1% | Added |
| Farallon Capital Management, L.L.C. | 3,700,608 | $29.3M | 0.17% | +2,566,151+226.2% | Added |
| FMR LLC | 3,491,006 | $27.6M | 0.00% | −3,637,573−51.0% | Reduced |
| BlackRock Inc. | 3,454,916 | $27.3M | 0.00% | +208,742+6.4% | Added |
| Vanguard Group Inc | 2,734,765 | $21.6M | 0.00% | +404,691+17.4% | Added |
| Johnson & Johnson | 2,449,183 | $19.4M | 4.95% | 00.0% | Unchanged |
| Bain Capital Life Sciences Investors, LLC | 2,260,572 | $17.9M | 2.10% | +2,260,572 | New |
| Morgan Stanley | 1,776,452 | $14.1M | 0.00% | +439,349+32.9% | Added |
| BVF Inc | 1,106,838 | $8.76M | 0.42% | −3,076,381−73.5% | Reduced |
| Millennium Management LLC | 1,089,528 | $8.62M | 0.01% | +629,413+136.8% | Added |
| Cowen and Company, LLC | 1,065,724 | $8.43M | 0.83% | +343,149+47.5% | Added |
| Adage Capital Partners GP, L.L.C. | 1,000,045 | $7.91M | 0.02% | +400,000+66.7% | Added |
| Dimensional Fund Advisors LP | 852,775 | $6.75M | 0.00% | −10,117−1.2% | Reduced |
| Geode Capital Management, LLC | 821,921 | $6.50M | 0.00% | −11,000−1.3% | Reduced |
| Deutsche Bank AG | 817,832 | $6.47M | 0.00% | −4,491−0.5% | Reduced |
| Finepoint Capital LP | 735,126 | $5.82M | 2.01% | +735,126 | New |
| Goldman Sachs Group Inc | 631,916 | $5.00M | 0.00% | +285,557+82.4% | Added |
| Voloridge Investment Management, LLC | 596,487 | $4.72M | 0.02% | +519,886+678.7% | Added |
| Two Sigma Advisers, LP | 518,400 | $4.10M | 0.01% | +303,700+141.5% | Added |
| Marshall Wace, LLP | 464,057 | $3.67M | 0.01% | +464,057 | New |
| Northern Trust Corp | 423,454 | $3.35M | 0.00% | −11,624−2.7% | Reduced |
| Woodline Partners LP | 388,637 | $3.07M | 0.05% | −200,057−34.0% | Reduced |
| Rothschild & Co Asset Management US Inc. | 367,117 | $2.90M | 0.04% | −12,009−3.2% | Reduced |
| Nuveen Asset Management, LLC | 337,972 | $2.67M | 0.00% | +33,860+11.1% | Added |
| Charles Schwab Investment Management Inc | 324,758 | $2.57M | 0.00% | −501−0.2% | Reduced |
| Renaissance Technologies LLC | 322,867 | $2.55M | 0.00% | +303,400+1,558.5% | Added |
| Caas Capital Management LP | 320,426 | $2.54M | 0.34% | +320,426 | New |
| Citigroup Inc | 317,499 | $2.51M | 0.00% | +281,843+790.5% | Added |
| Two Sigma Investments, LP | 315,644 | $2.50M | 0.01% | +27,126+9.4% | Added |
| Rafferty Asset Management, LLC | 314,232 | $2.49M | 0.02% | +106,138+51.0% | Added |
| Bank of America Corp | 307,230 | $2.43M | 0.00% | +59,354+23.9% | Added |
| Russell Investments Group, Ltd. | 289,562 | $2.29M | 0.00% | +106,446+58.1% | Added |
| Walleye Capital LLC | 257,357 | $2.04M | 0.06% | +223,967+670.8% | Added |
| UBS Oconnor LLC | 219,820 | $1.74M | 0.02% | +219,820 | New |
| Allianz Asset Management GmbH | 164,075 | $1.30M | 0.00% | +31,341+23.6% | Added |
| SG Americas Securities, LLC | 153,033 | $1.21M | 0.02% | +120,074+364.3% | Added |
| Bank of New York Mellon Corp | 142,071 | $1.12M | 0.00% | +2,302+1.6% | Added |
| Occudo Quantitative Strategies LP | 138,395 | $1.09M | 0.09% | +115,035+492.4% | Added |
| UBS Group AG | 128,987 | $1.02M | 0.00% | +6,222+5.1% | Added |
| Tekla Capital Management LLC | 122,271 | $967.0K | 0.04% | 00.0% | Unchanged |
| SEI Investments Co | 121,005 | $957.0K | 0.00% | −9,713−7.4% | Reduced |
| JPMorgan Chase & Co | 120,495 | $954.0K | 0.00% | +51,312+74.2% | Added |
| Capital Fund Management S.A. | 116,807 | $923.9K | 0.02% | +116,807 | New |
| Silvercrest Asset Management Group LLC | 114,759 | $908.0K | 0.01% | −5,075−4.2% | Reduced |
| ExodusPoint Capital Management, LP | 111,126 | $879.0K | 0.01% | +111,126 | New |
| Kennedy Capital Management, Inc. | 99,176 | $784.0K | 0.02% | +1,911+2.0% | Added |
| PDT Partners, LLC | 88,578 | $701.0K | 0.06% | +72,610+454.7% | Added |
| Algert Global LLC | 88,097 | $697.0K | 0.05% | +63,780+262.3% | Added |
| Swiss National Bank | 84,300 | $667.0K | 0.00% | −17,200−16.9% | Reduced |
| Citadel Advisors LLC | 74,129 | $586.0K | 0.00% | −112,695−60.3% | Reduced |
| Los Angeles Capital Management LLC | 70,930 | $561.0K | 0.00% | +70,930 | New |
| Rhumbline Advisers | 66,566 | $527.0K | 0.00% | +20,140+43.4% | Added |
| Susquehanna International Group, LLP | 65,160 | $516.0K | 0.00% | +14,406+28.4% | Added |
| Caxton Associates LP | 61,370 | $485.0K | 0.06% | +61,370 | New |
| Boothbay Fund Management, LLC | 57,923 | $458.0K | 0.02% | −98,718−63.0% | Reduced |
| First Manhattan Co | 55,800 | $441.0K | 0.00% | +55,800 | New |
| Squarepoint Ops LLC | 54,676 | $432.0K | 0.00% | +40,866+295.9% | Added |
| Jump Financial, LLC | 51,264 | $405.0K | 0.02% | +16,264+46.5% | Added |
| Tower Research Capital LLC (TRC) | 50,723 | $401.0K | 0.01% | +44,540+720.4% | Added |
| Amitell Capital Pte Ltd | 50,129 | $397.0K | 1.03% | 00.0% | Unchanged |
| California State Teachers Retirement System | 49,938 | $395.0K | 0.00% | −6,114−10.9% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 48,977 | $387.0K | 0.00% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 48,032 | $380.0K | 0.00% | +34,332+250.6% | Added |
| HighVista Strategies LLC | 46,459 | $367.0K | 0.22% | −45,586−49.5% | Reduced |
| Alliancebernstein L.P. | 46,000 | $364.0K | 0.00% | −80,463−63.6% | Reduced |
| State of Wisconsin Investment Board | 44,333 | $351.0K | 0.00% | −9,167−17.1% | Reduced |
| Group One Trading, L.P. | 43,914 | $347.0K | 0.01% | +32,897+298.6% | Added |
| BNP Paribas Arbitrage, SA | 43,637 | $345.2K | 0.00% | +24,489+127.9% | Added |
| Franklin Street Advisors Inc | 42,220 | $334.0K | 0.03% | +20,000+90.0% | Added |
| Birchview Capital, LP | 38,000 | $301.0K | 0.22% | 00.0% | Unchanged |
| Jane Street Group, LLC | 37,956 | $300.0K | 0.00% | +37,956 | New |
| E Fund Management Co., Ltd. | 36,033 | $285.0K | 0.03% | +25,593+245.1% | Added |
| UBS Asset Management Americas Inc | 32,664 | $258.4K | 0.00% | 00.0% | Unchanged |
| Credit Suisse AG | 31,815 | $251.0K | 0.00% | −1,083−3.3% | Reduced |
| Invesco Ltd. | 29,503 | $233.0K | 0.00% | −523−1.7% | Reduced |
| Alps Advisors Inc | 28,869 | $228.0K | 0.00% | −20,891−42.0% | Reduced |
| MetLife Investment Management | 23,914 | $189.2K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 23,531 | $186.0K | 0.00% | −20,771−46.9% | Reduced |
| New York State Common Retirement Fund | 22,300 | $176.0K | 0.00% | −10,906−32.8% | Reduced |
| King Wealth | 22,000 | $174.0K | 0.04% | 00.0% | Unchanged |
| American International Group, Inc. | 21,537 | $170.0K | 0.00% | −673−3.0% | Reduced |
| Twinbeech Capital LP | 20,317 | $161.0K | 0.01% | −26,508−56.6% | Reduced |
| Vontobel Holding Ltd. | 20,000 | $158.0K | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 19,388 | $153.4K | 0.00% | −20,987−52.0% | Reduced |
| Cubist Systematic Strategies, LLC | 19,029 | $151.0K | 0.00% | −9,107−32.4% | Reduced |
| Legal & General Group Plc | 18,126 | $143.0K | 0.00% | −3,468−16.1% | Reduced |
| DekaBank Deutsche Girozentrale | 15,800 | $140.0K | 0.00% | 00.0% | Unchanged |
| Voya Investment Management LLC | 17,368 | $137.0K | 0.00% | 00.0% | Unchanged |
| Dynamic Technology Lab Private Ltd | 17,326 | $137.0K | 0.02% | +1,816+11.7% | Added |
| Man Group plc | – | $133.0K | 0.00% | – | New |
| DuPont Capital Management Corp | 16,499 | $131.0K | 0.01% | +16,499 | New |
| Obermeyer Wood Investment Counsel, LLLP | 15,274 | $121.0K | 0.01% | −786,351−98.1% | Reduced |
| STRS Ohio | 15,300 | $121.0K | 0.00% | +2,600+20.5% | Added |
| First Trust Advisors LP | 14,328 | $113.0K | 0.00% | −27,444−65.7% | Reduced |
| Virtus ETF Advisers LLC | 14,129 | $112.0K | 0.04% | +8,913+170.9% | Added |
| Mirae Asset Global Investments Co., Ltd. | 13,923 | $110.0K | 0.00% | +13,923 | New |
| XTX Topco Ltd | 12,623 | $100.0K | 0.04% | +12,623 | New |
| Two Sigma Securities, LLC | 12,540 | $99.0K | 0.02% | +12,540 | New |