Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2022
Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 131
- −7 vs. Q1 2022
- Shares held
- 53.3M
- +2.76M (+5.5%) vs. Q1 2022
- Total value
- $422.1M
- −$771.0M (−64.6%) vs. Q1 2022
- New holders
- 28
- 44 more added
- Sold out
- 35
- 38 more reduced
2 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 9 | $0 | 0.00% | −2−18.2% | Reduced |
| Lindbrook Capital, LLC | 26 | $0 | 0.00% | +26 | New |
| Daiwa Securities Group Inc. | 163 | $1.00K | 0.00% | 00.0% | Unchanged |
| Macquarie Group Ltd | 307 | $2.00K | 0.00% | 00.0% | Unchanged |
| Truvestments Capital LLC | 345 | $3.00K | 0.00% | +345 | New |
| Leonteq Securities AG | 470 | $3.72K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 510 | $4.00K | 0.00% | −2,490−83.0% | Reduced |
| Dark Forest Capital Management LP | 525 | $4.00K | 0.00% | +525 | New |
| Eagle Bay Advisors LLC | 1,000 | $7.91K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 2,000 | $16.0K | 0.00% | −24,390−92.4% | Reduced |
| Great West Life Assurance Co | 1,982 | $16.0K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 2,921 | $23.1K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 3,501 | $27.0K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 5,625 | $44.0K | 0.00% | −20,394−78.4% | Reduced |
| Amalgamated Bank | 5,765 | $46.0K | 0.00% | −1,530−21.0% | Reduced |
| Lazard Asset Management LLC | 6,404 | $50.0K | 0.00% | +6,404 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 7,199 | $57.0K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 9,637 | $76.0K | 0.00% | +4,665+93.8% | Added |
| Quantbot Technologies LP | 9,658 | $76.0K | 0.01% | +9,658 | New |
| Allspring Global Investments Holdings, LLC | 10,312 | $81.0K | 0.00% | −16,994−62.2% | Reduced |
| Caption Management, LLC | 10,400 | $82.0K | 0.01% | −59,600−85.1% | Reduced |
| Atom Investors LP | 10,338 | $82.0K | 0.04% | +10,338 | New |
| Ensign Peak Advisors, Inc | 10,680 | $84.0K | 0.00% | 00.0% | Unchanged |
| Corton Capital Inc. | 10,836 | $86.0K | 0.08% | +10,836 | New |
| State Board of Administration of Florida Retirement System | 10,963 | $87.0K | 0.00% | +10+0.1% | Added |
| Quantamental Technologies LLC | 11,170 | $88.0K | 0.04% | +11,170 | New |
| Engineers Gate Manager LP | 11,383 | $90.0K | 0.00% | −45,380−79.9% | Reduced |
| Cerity Partners LLC | 11,640 | $92.0K | 0.00% | +11,640 | New |
| Delphia (USA) Inc. | 11,845 | $94.0K | 0.06% | +11,845 | New |
| Two Sigma Securities, LLC | 12,540 | $99.0K | 0.02% | +12,540 | New |
| XTX Topco Ltd | 12,623 | $100.0K | 0.04% | +12,623 | New |
| Mirae Asset Global Investments Co., Ltd. | 13,923 | $110.0K | 0.00% | +13,923 | New |
| Virtus ETF Advisers LLC | 14,129 | $112.0K | 0.04% | +8,913+170.9% | Added |
| First Trust Advisors LP | 14,328 | $113.0K | 0.00% | −27,444−65.7% | Reduced |
| Obermeyer Wood Investment Counsel, LLLP | 15,274 | $121.0K | 0.01% | −786,351−98.1% | Reduced |
| STRS Ohio | 15,300 | $121.0K | 0.00% | +2,600+20.5% | Added |
| DuPont Capital Management Corp | 16,499 | $131.0K | 0.01% | +16,499 | New |
| Man Group plc | – | $133.0K | 0.00% | – | New |
| Voya Investment Management LLC | 17,368 | $137.0K | 0.00% | 00.0% | Unchanged |
| Dynamic Technology Lab Private Ltd | 17,326 | $137.0K | 0.02% | +1,816+11.7% | Added |
| DekaBank Deutsche Girozentrale | 15,800 | $140.0K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 18,126 | $143.0K | 0.00% | −3,468−16.1% | Reduced |
| Cubist Systematic Strategies, LLC | 19,029 | $151.0K | 0.00% | −9,107−32.4% | Reduced |
| Manufacturers Life Insurance Company, The | 19,388 | $153.4K | 0.00% | −20,987−52.0% | Reduced |
| Vontobel Holding Ltd. | 20,000 | $158.0K | 0.00% | 00.0% | Unchanged |
| Twinbeech Capital LP | 20,317 | $161.0K | 0.01% | −26,508−56.6% | Reduced |
| American International Group, Inc. | 21,537 | $170.0K | 0.00% | −673−3.0% | Reduced |
| King Wealth | 22,000 | $174.0K | 0.04% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 22,300 | $176.0K | 0.00% | −10,906−32.8% | Reduced |
| Barclays PLC | 23,531 | $186.0K | 0.00% | −20,771−46.9% | Reduced |
| MetLife Investment Management | 23,914 | $189.2K | 0.00% | 00.0% | Unchanged |
| Alps Advisors Inc | 28,869 | $228.0K | 0.00% | −20,891−42.0% | Reduced |
| Invesco Ltd. | 29,503 | $233.0K | 0.00% | −523−1.7% | Reduced |
| Credit Suisse AG | 31,815 | $251.0K | 0.00% | −1,083−3.3% | Reduced |
| UBS Asset Management Americas Inc | 32,664 | $258.4K | 0.00% | 00.0% | Unchanged |
| E Fund Management Co., Ltd. | 36,033 | $285.0K | 0.03% | +25,593+245.1% | Added |
| Jane Street Group, LLC | 37,956 | $300.0K | 0.00% | +37,956 | New |
| Birchview Capital, LP | 38,000 | $301.0K | 0.22% | 00.0% | Unchanged |
| Franklin Street Advisors Inc | 42,220 | $334.0K | 0.03% | +20,000+90.0% | Added |
| BNP Paribas Arbitrage, SA | 43,637 | $345.2K | 0.00% | +24,489+127.9% | Added |
| Group One Trading, L.P. | 43,914 | $347.0K | 0.01% | +32,897+298.6% | Added |
| State of Wisconsin Investment Board | 44,333 | $351.0K | 0.00% | −9,167−17.1% | Reduced |
| Alliancebernstein L.P. | 46,000 | $364.0K | 0.00% | −80,463−63.6% | Reduced |
| HighVista Strategies LLC | 46,459 | $367.0K | 0.22% | −45,586−49.5% | Reduced |
| Schonfeld Strategic Advisors LLC | 48,032 | $380.0K | 0.00% | +34,332+250.6% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 48,977 | $387.0K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 49,938 | $395.0K | 0.00% | −6,114−10.9% | Reduced |
| Amitell Capital Pte Ltd | 50,129 | $397.0K | 1.03% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 50,723 | $401.0K | 0.01% | +44,540+720.4% | Added |
| Jump Financial, LLC | 51,264 | $405.0K | 0.02% | +16,264+46.5% | Added |
| Squarepoint Ops LLC | 54,676 | $432.0K | 0.00% | +40,866+295.9% | Added |
| First Manhattan Co | 55,800 | $441.0K | 0.00% | +55,800 | New |
| Boothbay Fund Management, LLC | 57,923 | $458.0K | 0.02% | −98,718−63.0% | Reduced |
| Caxton Associates LP | 61,370 | $485.0K | 0.06% | +61,370 | New |
| Susquehanna International Group, LLP | 65,160 | $516.0K | 0.00% | +14,406+28.4% | Added |
| Rhumbline Advisers | 66,566 | $527.0K | 0.00% | +20,140+43.4% | Added |
| Los Angeles Capital Management LLC | 70,930 | $561.0K | 0.00% | +70,930 | New |
| Citadel Advisors LLC | 74,129 | $586.0K | 0.00% | −112,695−60.3% | Reduced |
| Swiss National Bank | 84,300 | $667.0K | 0.00% | −17,200−16.9% | Reduced |
| Algert Global LLC | 88,097 | $697.0K | 0.05% | +63,780+262.3% | Added |
| PDT Partners, LLC | 88,578 | $701.0K | 0.06% | +72,610+454.7% | Added |
| Kennedy Capital Management, Inc. | 99,176 | $784.0K | 0.02% | +1,911+2.0% | Added |
| ExodusPoint Capital Management, LP | 111,126 | $879.0K | 0.01% | +111,126 | New |
| Silvercrest Asset Management Group LLC | 114,759 | $908.0K | 0.01% | −5,075−4.2% | Reduced |
| Capital Fund Management S.A. | 116,807 | $923.9K | 0.02% | +116,807 | New |
| JPMorgan Chase & Co | 120,495 | $954.0K | 0.00% | +51,312+74.2% | Added |
| SEI Investments Co | 121,005 | $957.0K | 0.00% | −9,713−7.4% | Reduced |
| Tekla Capital Management LLC | 122,271 | $967.0K | 0.04% | 00.0% | Unchanged |
| UBS Group AG | 128,987 | $1.02M | 0.00% | +6,222+5.1% | Added |
| Occudo Quantitative Strategies LP | 138,395 | $1.09M | 0.09% | +115,035+492.4% | Added |
| Bank of New York Mellon Corp | 142,071 | $1.12M | 0.00% | +2,302+1.6% | Added |
| SG Americas Securities, LLC | 153,033 | $1.21M | 0.02% | +120,074+364.3% | Added |
| Allianz Asset Management GmbH | 164,075 | $1.30M | 0.00% | +31,341+23.6% | Added |
| UBS Oconnor LLC | 219,820 | $1.74M | 0.02% | +219,820 | New |
| Walleye Capital LLC | 257,357 | $2.04M | 0.06% | +223,967+670.8% | Added |
| Russell Investments Group, Ltd. | 289,562 | $2.29M | 0.00% | +106,446+58.1% | Added |
| Bank of America Corp | 307,230 | $2.43M | 0.00% | +59,354+23.9% | Added |
| Rafferty Asset Management, LLC | 314,232 | $2.49M | 0.02% | +106,138+51.0% | Added |
| Two Sigma Investments, LP | 315,644 | $2.50M | 0.01% | +27,126+9.4% | Added |
| Citigroup Inc | 317,499 | $2.51M | 0.00% | +281,843+790.5% | Added |