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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2021

Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
127
No complete 13F data for Q4 2020
Shares held
44.3M
No complete 13F data for Q4 2020
Total value
$1.15B
No complete 13F data for Q4 2020

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2021: 127 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ1 2021: $1.15B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q1 2021

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc.

Livermore's 13F data starts with Q1 2021, so Q1 2021 has no change from the previous quarter.

Institutions holding PTGX in Q1 2021
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC6,571,227$170.2M0.01%––
BVF Inc3,959,451$102.5M3.84%––
RTW Investments, LP3,507,390$90.8M1.42%––
BlackRock Inc.3,001,629$77.7M0.00%––
Consonance Capital Management LP2,709,709$70.2M7.48%––
Johnson & Johnson Innovation - JJDC, Inc.2,449,183$63.4M8.22%––
Farallon Capital Management, L.L.C.2,425,000$62.8M0.33%––
Vanguard Group Inc2,140,547$55.4M0.00%––
State Street Corp1,712,683$44.4M0.00%––
Baker Bros. Advisors LP1,436,192$37.2M0.16%––
Deerfield Management Company, L.P. (Series C)1,258,790$32.6M0.69%––
Point72 Asset Management, L.P.942,300$24.4M0.12%––
Price T Rowe Associates Inc913,590$23.7M0.00%––
Novo Holdings A/S867,724$22.5M0.93%––
Dimensional Fund Advisors LP656,101$17.0M0.01%––
Sofinnova Investments, Inc.654,900$17.0M1.07%––
Geode Capital Management, LLC645,679$16.7M0.00%––
Adage Capital Partners GP, L.L.C.600,045$15.5M0.03%––
JPMorgan Chase & Co584,897$15.1M0.00%––
Rothschild & Co Asset Management US Inc.434,249$11.2M0.14%––
Northern Trust Corp415,513$10.8M0.00%––
Goldman Sachs Group Inc414,134$10.7M0.00%––
Obermeyer Wood Investment Counsel, LLLP386,072$10.0M0.61%––
Commodore Capital LP349,600$9.05M3.61%––
Two Sigma Advisers, LP346,675$8.98M0.02%––
Opaleye Management Inc.297,000$7.69M1.13%––
Charles Schwab Investment Management Inc261,587$6.78M0.00%––
Tri Locum Partners LP257,086$6.66M2.12%––
Altium Capital Management LP238,354$6.17M1.71%––
Panagora Asset Management Inc229,513$5.94M0.03%––
Sphera Funds Management Ltd.202,134$5.24M0.48%––
D. E. Shaw & Co., Inc.200,980$5.21M0.01%––
Citadel Advisors LLC198,218$5.13M0.01%––
International Biotechnology Trust PLC152,000$3.94M1.04%––
Laurion Capital Management LP147,405$3.82M0.05%––
Twin Lakes Capital Management, LLC142,884$3.70M2.28%––
Bank of New York Mellon Corp133,595$3.46M0.00%––
Citigroup Inc95,720$2.48M0.00%––
Bank of Montreal90,073$2.40M0.00%––
SEI Investments Co86,880$2.25M0.01%––
Marshall Wace, LLP86,691$2.25M0.01%––
Swiss National Bank83,600$2.17M0.00%––
Two Sigma Investments, LP83,516$2.16M0.01%––
Rafferty Asset Management, LLC75,976$1.97M0.01%––
Kennedy Capital Management, Inc.75,518$1.96M0.04%––
Artal Group S.A.75,000$1.94M0.04%––
Allianz Asset Management GmbH74,260$1.92M0.00%––
California Public Employees Retirement System67,400$1.75M0.00%––
TD Asset Management Inc61,471$1.59M0.00%––
Canada Pension Plan Investment Board55,000$1.43M0.00%––
State of Wisconsin Investment Board53,700$1.39M0.00%––
California State Teachers Retirement System53,123$1.38M0.00%––
Russell Investments Group, Ltd.50,733$1.31M0.00%––
Affinity Asset Advisors, LLC50,000$1.29M0.63%––
J. Goldman & Co LP49,579$1.28M0.08%––
Susquehanna Fundamental Investments, LLC47,620$1.23M0.02%––
Los Angeles Capital Management LLC47,387$1.23M0.01%––
UBS Group AG44,573$1.15M0.00%––
Marshall Wace North America L.P.44,385$1.15M0.00%––
Nuveen Asset Management, LLC144,700$1.12M0.00%––
Bank of America Corp41,715$1.08M0.00%––
Parametric Portfolio Associates LLC40,199$1.04M0.00%––
Wells Fargo & Company38,435$995.0K0.00%––
Barclays PLC37,866$981.0K0.00%––
Susquehanna International Group, LLP34,134$884.0K0.00%––
Prudential Financial Inc33,615$871.0K0.00%––
Ensign Peak Advisors, Inc33,230$861.0K0.00%––
Rhumbline Advisers33,215$860.0K0.00%––
Alliancebernstein L.P.30,600$793.0K0.00%––
Atom Investors LP30,542$791.0K0.15%––
AQR Capital Management LLC30,387$787.0K0.00%––
Ameriprise Financial Inc28,488$737.0K0.00%––
New York State Common Retirement Fund27,500$712.0K0.00%––
Deutsche Bank AG25,561$662.0K0.00%––
UBS Asset Management Americas Inc25,000$647.5K0.00%––
Franklin Street Advisors Inc22,250$576.0K0.05%––
King Wealth22,000$570.0K0.13%––
Credit Suisse AG21,240$549.0K0.00%––
American International Group, Inc.20,527$532.0K0.00%––
Manufacturers Life Insurance Company, The20,039$519.0K0.00%––
Bingham Osborn & Scarborough LLC15,640$405.0K0.03%––
ProShare Advisors LLC15,367$398.0K0.00%––
Voya Investment Management LLC15,094$391.0K0.00%––
Cubist Systematic Strategies, LLC14,700$381.0K0.00%––
Virtus ETF Advisers LLC14,346$372.0K0.16%––
DekaBank Deutsche Girozentrale14,000$354.0K0.00%––
Kestra Advisory Services, LLC13,629$353.0K0.00%––
MetLife Investment Management13,524$350.3K0.00%––
Qube Research & Technologies Ltd13,465$349.0K0.01%––
Millennium Management LLC10,892$282.0K0.00%––
Arizona State Retirement System10,644$276.0K0.00%––
Legal & General Group Plc10,545$273.0K0.00%––
Trexquant Investment LP10,522$273.0K0.03%––
Invesco Ltd.10,103$262.0K0.00%––
STRS Ohio10,000$259.0K0.00%––
Vontobel Holding Ltd.10,000$259.0K0.00%––
Birchview Capital, LP10,000$259.0K0.15%––
Metropolitan Life Insurance Co9,284$240.5K0.00%––
Athanor Capital, LP8,748$227.0K0.01%––
SG Americas Securities, LLC8,725$226.0K0.00%––