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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2023

Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
167
+29 vs. Q1 2023
Shares held
56.7M
+3.51M (+6.6%) vs. Q1 2023
Total value
$1.57B
+$342.2M (+27.9%) vs. Q1 2023
New holders
43
60 more added
Sold out
14
48 more reduced

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 167 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ2 2023: $1.57B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2023.

Institutions holding PTGX in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
RTW Investments, LP5,415,514$149.6M2.85%+814,715+17.7%Added
BlackRock Inc.5,009,273$138.4M0.00%+607,056+13.8%Added
Farallon Capital Management, L.L.C.4,511,430$124.6M0.74%+1,896,416+72.5%Added
BVF Inc3,775,900$104.3M2.91%00.0%Unchanged
State Street Corp3,551,986$98.1M0.01%+1,138,285+47.2%Added
Vanguard Group Inc3,147,755$86.9M0.00%−93,538−2.9%Reduced
Johnson & Johnson2,449,183$67.6M21.00%00.0%Unchanged
Cowen and Company, LLC1,657,551$45.8M3.79%+1,657,551New
Cormorant Asset Management, LP1,500,000$41.4M2.36%−200,000−11.8%Reduced
Perceptive Advisors LLC1,469,761$40.6M1.18%+504,609+52.3%Added
Adage Capital Partners GP, L.L.C.1,292,711$35.7M0.08%−1,265,289−49.5%Reduced
Geode Capital Management, LLC1,077,184$29.8M0.00%+151,191+16.3%Added
Dimensional Fund Advisors LP1,039,105$28.7M0.01%−223,154−17.7%Reduced
Kynam Capital Management, LP975,298$26.9M4.13%−399,702−29.1%Reduced
Nuveen Asset Management, LLC935,961$25.9M0.01%+107,490+13.0%Added
Deutsche Bank AG861,324$23.8M0.01%−97,567−10.2%Reduced
Price T Rowe Associates Inc831,693$23.0M0.00%+416,419+100.3%Added
683 Capital Management, LLC814,000$22.5M2.19%+23,000+2.9%Added
Holocene Advisors, LP802,531$22.2M0.10%+802,531New
Jefferies Financial Group Inc.760,561$21.0M0.45%+760,561New
Candriam Luxembourg S.C.A.725,000$20.0M0.14%+100,000+16.0%Added
Morgan Stanley578,021$16.0M0.00%−992,489−63.2%Reduced
HSBC Holdings PLC560,455$15.7M0.02%+560,455New
Goldman Sachs Group Inc559,210$15.4M0.00%+99,760+21.7%Added
Citadel Advisors LLC548,994$15.2M0.02%−615,686−52.9%Reduced
Northern Trust Corp538,125$14.9M0.00%+115,489+27.3%Added
FMR LLC507,407$14.0M0.00%+459,087+950.1%Added
Artal Group S.A.500,000$13.8M0.44%+500,000New
Woodline Partners LP427,264$11.8M0.14%−191,351−30.9%Reduced
Charles Schwab Investment Management Inc419,610$11.6M0.00%+58,452+16.2%Added
Two Sigma Advisers, LP412,100$11.4M0.03%−37,700−8.4%Reduced
Kennedy Capital Management, Inc.403,648$11.1M0.26%+72,366+21.8%Added
Renaissance Technologies LLC390,267$10.8M0.02%−300,600−43.5%Reduced
Two Sigma Investments, LP376,473$10.4M0.03%+68,773+22.4%Added
Millennium Management LLC351,810$9.72M0.01%−770,532−68.7%Reduced
Eventide Asset Management, LLC320,000$8.84M0.15%+320,000New
Bank of Montreal310,000$8.68M0.01%+310,000New
Bank of America Corp296,240$8.18M0.00%−470,750−61.4%Reduced
Rafferty Asset Management, LLC285,459$7.88M0.04%+132,072+86.1%Added
JPMorgan Chase & Co264,707$7.31M0.00%+158,574+149.4%Added
Invesco Ltd.264,411$7.30M0.00%−13,525−4.9%Reduced
Ghost Tree Capital, LLC225,000$6.21M2.24%00.0%Unchanged
Gratus Capital LLC219,586$6.06M0.42%+7,855+3.7%Added
Readystate Asset Management LP204,880$5.66M0.56%+204,880New
BNP Paribas Arbitrage, SA202,310$5.59M0.01%−35,314−14.9%Reduced
Bank of New York Mellon Corp199,575$5.51M0.00%+31,042+18.4%Added
SG Americas Securities, LLC195,756$5.41M0.05%+177,241+957.3%Added
Barclays PLC193,439$5.34M0.00%−390,298−66.9%Reduced
Allspring Global Investments Holdings, LLC175,529$4.85M0.01%−48,135−21.5%Reduced
Marshall Wace, LLP164,500$4.54M0.01%−1,201,580−88.0%Reduced
Connor, Clark & Lunn Investment Management Ltd.163,425$4.51M0.02%+41,401+33.9%Added
Great Lakes Advisors, LLC147,048$4.06M0.04%−3,436−2.3%Reduced
Jacobs Levy Equity Management, Inc146,487$4.05M0.02%−74,504−33.7%Reduced
Public Sector Pension Investment Board146,000$4.03M0.03%00.0%Unchanged
Silvercrest Asset Management Group LLC128,197$3.54M0.03%+14,842+13.1%Added
Eversept Partners, LP114,659$3.17M0.33%+114,659New
Artia Global Partners LP112,340$3.10M1.07%+112,340New
Citigroup Inc107,521$2.97M0.00%−84,828−44.1%Reduced
Ameriprise Financial Inc99,930$2.76M0.00%+81,572+444.3%Added
Swiss National Bank98,000$2.71M0.00%+18,300+23.0%Added
EAM Investors, LLC87,953$2.43M0.45%+87,953New
Suvretta Capital Management, LLC81,143$2.24M0.12%+81,143New
Alliancebernstein L.P.80,200$2.22M0.00%+26,000+48.0%Added
Rhumbline Advisers77,911$2.15M0.00%+3,202+4.3%Added
Integral Health Asset Management, LLC75,000$2.07M0.27%+75,000New
Thrivent Financial for Lutherans73,381$2.03M0.00%−27,612−27.3%Reduced
D. E. Shaw & Co., Inc.72,686$2.01M0.00%−126,830−63.6%Reduced
SEI Investments Co72,016$1.99M0.00%+36,377+102.1%Added
Wells Fargo & Company71,051$1.96M0.00%+37,087+109.2%Added
UBS Oconnor LLC67,094$1.85M0.04%−41,379−38.1%Reduced
Manufacturers Life Insurance Company, The65,892$1.82M0.00%+21,037+46.9%Added
UBS Group AG65,540$1.81M0.00%−50,399−43.5%Reduced
Credit Suisse AG62,834$1.74M0.00%+24,833+65.3%Added
California State Teachers Retirement System57,648$1.59M0.00%+7,934+16.0%Added
TD Asset Management Inc55,400$1.53M0.00%+26,400+91.0%Added
UBS Asset Management Americas Inc64,778$1.49M0.00%00.0%Unchanged
Walleye Capital LLC52,661$1.45M0.03%−74,709−58.7%Reduced
Profund Advisors LLC51,783$1.43M0.08%+22,983+79.8%Added
Ghisallo Capital Management LLC50,000$1.38M0.16%+50,000New
State of Wisconsin Investment Board49,677$1.37M0.00%+13,508+37.3%Added
Legal & General Group Plc44,500$1.23M0.00%+25,364+132.5%Added
Harvest Investment Services, LLC44,113$1.22M0.69%+44,113New
Russell Investments Group, Ltd.43,522$1.20M0.00%−56,564−56.5%Reduced
Alps Advisors Inc42,081$1.16M0.01%+9,666+29.8%Added
Moody Aldrich Partners LLC41,860$1.16M0.22%+41,860New
Voya Investment Management LLC41,589$1.15M0.00%−52,468−55.8%Reduced
Franklin Resources Inc41,084$1.13M0.00%+8,551+26.3%Added
Soleus Capital Management, L.P.39,800$1.10M0.12%+39,800New
Birchview Capital, LP38,000$1.05M0.79%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.35,667$985.6K0.00%+8,038+29.1%Added
Ikarian Capital, LLC35,000$966.7K0.34%+35,000New
Tri Locum Partners LP33,750$932.2K0.35%−99,702−74.7%Reduced
Tudor Investment Corp Et Al33,338$920.8K0.02%−4,002−10.7%Reduced
Federated Hermes, Inc.29,727$821.1K0.00%+74+0.2%Added
HighVista Strategies LLC29,179$805.9K0.37%+29,179New
MetLife Investment Management28,596$789.8K0.01%+4,682+19.6%Added
Fox Run Management, L.L.C.27,931$771.5K0.22%+27,931New
Algert Global LLC27,230$752.1K0.03%+6,170+29.3%Added
Seven Eight Capital, LP27,092$748.3K0.12%+27,092New
Capital Fund Management S.A.26,605$734.8K0.01%+26,605New