Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2024
Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 185
- +28 vs. Q4 2023
- Shares held
- 60.0M
- +2.49M (+4.3%) vs. Q4 2023
- Total value
- $1.73B
- +$416.8M (+31.6%) vs. Q4 2023
- New holders
- 49
- 62 more added
- Sold out
- 21
- 56 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Farallon Capital Management, L.L.C. | 5,738,973 | $166.0M | 0.98% | +4,543+0.1% | Added |
| BlackRock Inc. | 5,569,485 | $161.1M | 0.00% | +25,583+0.5% | Added |
| RTW Investments, LP | 5,315,514 | $153.8M | 2.27% | 00.0% | Unchanged |
| BVF Inc | 3,755,990 | $108.7M | 2.99% | −1,988,858−34.6% | Reduced |
| State Street Corp | 3,272,485 | $94.7M | 0.00% | +542,556+19.9% | Added |
| Vanguard Group Inc | 3,192,971 | $92.4M | 0.00% | +39,055+1.2% | Added |
| Johnson & Johnson | 2,449,183 | $70.9M | 1.61% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 2,218,868 | $64.2M | 0.12% | +927,167+71.8% | Added |
| Morgan Stanley | 1,879,878 | $54.4M | 0.00% | +688,041+57.7% | Added |
| Cowen and Company, LLC | 1,557,636 | $45.1M | 1.76% | +1,557,636 | New |
| Geode Capital Management, LLC | 1,293,739 | $37.4M | 0.00% | +45,455+3.6% | Added |
| Point72 Asset Management, L.P. | 1,199,902 | $34.7M | 0.10% | −1,413,551−54.1% | Reduced |
| Jefferies Financial Group Inc. | 1,180,561 | $34.2M | 0.69% | −90,000−7.1% | Reduced |
| Kynam Capital Management, LP | 1,144,242 | $33.1M | 3.68% | −860,633−42.9% | Reduced |
| Perceptive Advisors LLC | 994,323 | $28.8M | 0.51% | +611,063+159.4% | Added |
| Marshall Wace, LLP | 976,893 | $28.3M | 0.05% | +834,423+585.7% | Added |
| Fairmount Funds Management LLC | 931,890 | $27.0M | 2.94% | +931,890 | New |
| Deutsche Bank AG | 910,806 | $26.3M | 0.01% | +794+0.1% | Added |
| Price T Rowe Associates Inc | 819,296 | $23.7M | 0.00% | −4,444−0.5% | Reduced |
| Dimensional Fund Advisors LP | 791,344 | $22.9M | 0.01% | −25,193−3.1% | Reduced |
| ADAR1 Capital Management, LLC | 785,655 | $22.7M | 6.21% | +584,796+291.1% | Added |
| 683 Capital Management, LLC | 700,000 | $20.3M | 2.07% | −15,000−2.1% | Reduced |
| Nuveen Asset Management, LLC | 678,201 | $19.6M | 0.01% | +372,782+122.1% | Added |
| Woodline Partners LP | 636,956 | $18.4M | 0.17% | +636,956 | New |
| Driehaus Capital Management LLC | 560,530 | $16.2M | 0.16% | +361,841+182.1% | Added |
| Northern Trust Corp | 538,995 | $15.6M | 0.00% | −11,144−2.0% | Reduced |
| Goldman Sachs Group Inc | 525,040 | $15.2M | 0.00% | +9,820+1.9% | Added |
| Charles Schwab Investment Management Inc | 496,562 | $14.4M | 0.00% | +41,241+9.1% | Added |
| FMR LLC | 466,085 | $13.5M | 0.00% | +1330.0% | Added |
| Mangrove Partners | 439,314 | $12.7M | 1.10% | 00.0% | Unchanged |
| Eversept Partners, LP | 411,478 | $11.9M | 0.89% | −126,596−23.5% | Reduced |
| Gratus Capital LLC | 408,173 | $11.8M | 0.54% | +10,602+2.7% | Added |
| Candriam Luxembourg S.C.A. | 360,000 | $10.4M | 0.07% | −177,000−33.0% | Reduced |
| UBS Asset Management Americas Inc | 335,318 | $9.70M | 0.00% | +46,239+16.0% | Added |
| Kennedy Capital Management, Inc. | 298,068 | $8.62M | 0.18% | −6,722−2.2% | Reduced |
| Checkpoint Capital L.P. | 280,301 | $8.11M | 5.42% | +13,445+5.0% | Added |
| Bank of America Corp | 266,551 | $7.71M | 0.00% | +113,142+73.8% | Added |
| Rafferty Asset Management, LLC | 239,208 | $6.92M | 0.03% | +71,413+42.6% | Added |
| JPMorgan Chase & Co | 237,440 | $6.87M | 0.00% | −173,606−42.2% | Reduced |
| Citigroup Inc | 208,641 | $6.04M | 0.01% | +135,938+187.0% | Added |
| CIBC World Markets Corp | 200,000 | $5.79M | 0.04% | +200,000 | New |
| Rubric Capital Management LP | 198,059 | $5.73M | 0.17% | +198,059 | New |
| Two Sigma Advisers, LP | 196,700 | $5.69M | 0.01% | −25,300−11.4% | Reduced |
| Silvercrest Asset Management Group LLC | 188,743 | $5.46M | 0.04% | +8,247+4.6% | Added |
| Bank of New York Mellon Corp | 187,234 | $5.42M | 0.00% | −15,943−7.8% | Reduced |
| UBS Group AG | 177,546 | $5.14M | 0.00% | +26,679+17.7% | Added |
| American Century Companies Inc | 160,320 | $4.64M | 0.00% | +121,976+318.1% | Added |
| Two Sigma Investments, LP | 157,594 | $4.56M | 0.01% | −1,249−0.8% | Reduced |
| Algert Global LLC | 147,843 | $4.28M | 0.17% | +72,083+95.1% | Added |
| Walleye Capital LLC | 134,114 | $3.88M | 0.04% | −51,312−27.7% | Reduced |
| Jacobs Levy Equity Management, Inc | 129,011 | $3.73M | 0.02% | 00.0% | Unchanged |
| Artia Global Partners LP | 124,440 | $3.60M | 0.88% | +12,100+10.8% | Added |
| Privium Fund Management B.V. | 114,024 | $3.30M | 0.88% | +114,024 | New |
| HSBC Holdings PLC | 112,887 | $3.27M | 0.00% | −6,447−5.4% | Reduced |
| Opaleye Management Inc. | 112,700 | $3.26M | 0.71% | 00.0% | Unchanged |
| UBS Oconnor LLC | 109,330 | $3.16M | 0.09% | +3,176+3.0% | Added |
| TD Asset Management Inc | 108,452 | $3.14M | 0.00% | −2,348−2.1% | Reduced |
| Trexquant Investment LP | 102,379 | $2.96M | 0.06% | +102,379 | New |
| Moody Aldrich Partners LLC | 100,519 | $2.91M | 0.49% | +38,192+61.3% | Added |
| Affinity Asset Advisors, LLC | 100,000 | $2.89M | 0.47% | +100,000 | New |
| Great Lakes Advisors, LLC | 97,160 | $2.81M | 0.02% | +6,007+6.6% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 93,186 | $2.70M | 0.01% | −14,356−13.3% | Reduced |
| Swiss National Bank | 90,700 | $2.62M | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 89,657 | $2.59M | 0.00% | +21,225+31.0% | Added |
| CIBC World Markets Inc. | 87,000 | $2.52M | 0.01% | +87,000 | New |
| Alliancebernstein L.P. | 85,400 | $2.47M | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 84,989 | $2.46M | 0.00% | +1,697+2.0% | Added |
| Jane Street Group, LLC | 81,270 | $2.35M | 0.00% | +8,339+11.4% | Added |
| AQR Capital Management LLC | 81,007 | $2.34M | 0.00% | +71,665+767.1% | Added |
| Ghost Tree Capital, LLC | 75,000 | $2.17M | 0.70% | −50,000−40.0% | Reduced |
| Susquehanna International Group, LLP | 71,818 | $2.08M | 0.00% | −37,865−34.5% | Reduced |
| Voya Investment Management LLC | 69,443 | $2.01M | 0.00% | +26,198+60.6% | Added |
| Credit Suisse AG | 63,024 | $1.82M | 0.00% | +507+0.8% | Added |
| Qube Research & Technologies Ltd | 62,155 | $1.80M | 0.00% | +62,155 | New |
| Barclays PLC | 61,819 | $1.79M | 0.00% | −87,155−58.5% | Reduced |
| First Trust Advisors LP | 60,663 | $1.75M | 0.00% | +60,663 | New |
| Gsa Capital Partners LLP | 55,359 | $1.60M | 0.13% | +35,571+179.8% | Added |
| Knott David M Jr | 52,368 | $1.51M | 0.54% | 00.0% | Unchanged |
| Legal & General Group Plc | 50,686 | $1.47M | 0.00% | +5,397+11.9% | Added |
| Birchview Capital, LP | 48,000 | $1.39M | 1.13% | 00.0% | Unchanged |
| California State Teachers Retirement System | 47,239 | $1.37M | 0.00% | −3,153−6.3% | Reduced |
| BNP Paribas Arbitrage, SA | 47,233 | $1.37M | 0.00% | −24,665−34.3% | Reduced |
| Citadel Advisors LLC | 45,616 | $1.32M | 0.00% | −2,248−4.7% | Reduced |
| Millennium Management LLC | 42,865 | $1.24M | 0.00% | −106,298−71.3% | Reduced |
| SEI Investments Co | 41,758 | $1.21M | 0.00% | +4,529+12.2% | Added |
| State of Wisconsin Investment Board | 41,486 | $1.20M | 0.00% | +1,687+4.2% | Added |
| Alps Advisors Inc | 41,099 | $1.19M | 0.01% | +1,027+2.6% | Added |
| Resolute Capital Asset Partners LLC | 39,500 | $1.14M | 0.60% | +39,500 | New |
| Engineers Gate Manager LP | 37,570 | $1.09M | 0.03% | +25,048+200.0% | Added |
| Profund Advisors LLC | 37,475 | $1.08M | 0.04% | +9,585+34.4% | Added |
| D. E. Shaw & Co., Inc. | 35,640 | $1.03M | 0.00% | +35,640 | New |
| Hennion & Walsh Asset Management, Inc. | 34,895 | $1.01M | 0.05% | +849+2.5% | Added |
| Jackson Creek Investment Advisors LLC | 34,712 | $1.00M | 0.36% | +34,712 | New |
| Soleus Capital Management, L.P. | 34,500 | $998.1K | 0.09% | −48,500−58.4% | Reduced |
| Twinbeech Capital LP | 34,468 | $997.2K | 0.02% | +10,307+42.7% | Added |
| Renaissance Technologies LLC | 32,567 | $942.0K | 0.00% | −181,400−84.8% | Reduced |
| Franklin Resources Inc | 31,844 | $921.2K | 0.00% | +31,844 | New |
| Polar Asset Management Partners Inc. | 31,400 | $908.4K | 0.02% | +31,400 | New |
| Los Angeles Capital Management LLC | 30,827 | $891.8K | 0.00% | +21,673+236.8% | Added |
| Suvretta Capital Management, LLC | 30,500 | $882.4K | 0.04% | +30,500 | New |