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Protagonist Therapeutics, Inc

PTGX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001377121

In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 2 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2024

Institutional positions in Protagonist Therapeutics, Inc as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
185
+28 vs. Q4 2023
Shares held
60.0M
+2.49M (+4.3%) vs. Q4 2023
Total value
$1.73B
+$416.8M (+31.6%) vs. Q4 2023
New holders
49
62 more added
Sold out
21
56 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 185 institutions
Q1 2021: 127 institutionsQ2 2021: 139 institutionsQ3 2021: 132 institutionsQ4 2021: 149 institutionsQ1 2022: 140 institutionsQ2 2022: 131 institutionsQ3 2022: 133 institutionsQ4 2022: 137 institutionsQ1 2023: 138 institutionsQ2 2023: 167 institutionsQ3 2023: 144 institutionsQ4 2023: 157 institutionsQ1 2024: 185 institutionsQ2 2024: 188 institutionsQ3 2024: 240 institutionsQ4 2024: 241 institutionsQ1 2025: 275 institutionsQ2 2025: 274 institutionsQ3 2025: 275 institutionsQ4 2025: 319 institutionsQ1 2026: 322 institutionsQ2 2026: 346 institutions
Value heldQ1 2024: $1.73B
Q1 2021: $1.15BQ2 2021: $2.16BQ3 2021: $820.8MQ4 2021: $1.68BQ1 2022: $1.19BQ2 2022: $422.1MQ3 2022: $398.9MQ4 2022: $533.3MQ1 2023: $1.22BQ2 2023: $1.57BQ3 2023: $945.9MQ4 2023: $1.32BQ1 2024: $1.73BQ2 2024: $2.05BQ3 2024: $2.78BQ4 2024: $2.44BQ1 2025: $3.15BQ2 2025: $3.92BQ3 2025: $4.70BQ4 2025: $6.18BQ1 2026: $8.31BQ2 2026: $9.30B
Institutions holding PTGX and their total value by quarter
QuarterHoldersValue
Q2 2026346$9.30B
Q1 2026322$8.31B
Q4 2025319$6.18B
Q3 2025275$4.70B
Q2 2025274$3.92B
Q1 2025275$3.15B
Q4 2024241$2.44B
Q3 2024240$2.78B
Q2 2024188$2.05B
Q1 2024185$1.73B
Q4 2023157$1.32B
Q3 2023144$945.9M
Q2 2023167$1.57B
Q1 2023138$1.22B
Q4 2022137$533.3M
Q3 2022133$398.9M
Q2 2022131$422.1M
Q1 2022140$1.19B
Q4 2021149$1.68B
Q3 2021132$820.8M
Q2 2021139$2.16B
Q1 2021127$1.15B

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q4 2023.

Institutions holding PTGX in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd4$00.00%−1−20.0%Reduced
Rothschild Investment LLC5$1450.00%+5New
Principal Securities, Inc.6$1740.00%00.0%Unchanged
Nelson, Van Denburg & Campbell Wealth Management Group, LLC11$3180.00%+11New
Institutional & Family Asset Management, LLC16$4630.00%+16New
Bell Investment Advisors, Inc17$4920.00%+17New
Sofos Investments, Inc.18$5220.00%+18New
Farther Finance Advisors, LLC40$1.13K0.00%00.0%Unchanged
GAMMA Investing LLC48$1.39K0.00%+23+92.0%Added
Truvestments Capital LLC131$3.79K0.00%00.0%Unchanged
CWM, LLC175$5.00K0.00%+175New
Lindbrook Capital, LLC173$5.00K0.00%+173New
Hillsdale Investment Management Inc.200$5.79K0.00%+200New
Daiwa Securities Group Inc.215$6.00K0.00%+52+31.9%Added
Comerica Bank270$7.82K0.00%+43+18.9%Added
Global Retirement Partners, LLC300$8.68K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)322$9.31K0.00%−11,437−97.3%Reduced
CoreCap Advisors, LLC352$10.2K0.00%+352New
Pacer Advisors, Inc.1,113$32.2K0.00%+1,113New
KBC Group NV1,202$35.0K0.00%+1,202New
Russell Investments Group, Ltd.1,216$35.2K0.00%+1,216New
STRS Ohio1,900$54.0K0.00%−500−20.8%Reduced
Amalgamated Bank1,949$56.0K0.00%−4,912−71.6%Reduced
Allspring Global Investments Holdings, LLC1,970$57.0K0.00%−563−22.2%Reduced
Simplex Trading, LLC2,250$65.0K0.00%−584−20.6%Reduced
Aquatic Capital Management LLC2,300$66.5K0.00%−6,400−73.6%Reduced
Amundi2,707$68.3K0.00%+675+33.2%Added
Lazard Asset Management LLC2,415$69.0K0.00%+2,415New
Advisor Group Holdings, Inc.2,551$73.8K0.00%+2,270+807.8%Added
Nisa Investment Advisors, LLC2,691$77.9K0.00%+52+2.0%Added
nVerses Capital, LLC2,900$83.9K0.20%+2,900New
Metropolitan Life Insurance Co3,037$87.9K0.00%−315−9.4%Reduced
Virtus ETF Advisers LLC4,175$120.8K0.06%−282−6.3%Reduced
Royal Bank of Canada5,679$165.0K0.00%−11,776−67.5%Reduced
Quest Partners LLC5,900$170.7K0.03%+5,900New
Ameritas Investment Partners, Inc.5,912$171.0K0.01%00.0%Unchanged
Cubist Systematic Strategies, LLC5,995$173.4K0.00%+5,995New
US Bancorp6,286$181.9K0.00%−881−12.3%Reduced
Seven Eight Capital, LP6,983$202.0K0.02%+6,983New
Victory Capital Management Inc7,208$208.5K0.00%+7,208New
Catalyst Funds Management Pty Ltd7,520$217.6K0.06%+7,520New
State Board of Administration of Florida Retirement System11,323$260.4K0.00%−4,980−30.5%Reduced
Great West Life Assurance Co9,083$263.0K0.00%+3,870+74.2%Added
Verition Fund Management LLC9,182$265.6K0.00%+9,182New
PEAK6 Investments LLC9,303$269.1K0.01%+9,303New
Zurcher Kantonalbank (Zurich Cantonalbank)9,863$285.3K0.00%−475−4.6%Reduced
Teacher Retirement System of Texas10,270$297.0K0.00%−370−3.5%Reduced
Moran Wealth Management, LLC10,736$310.6K0.01%+10,736New
Raymond James & Associates10,951$316.8K0.00%+10,951New
Allianz Asset Management GmbH11,100$321.1K0.00%+11,100New
Envestnet Asset Management Inc11,169$323.1K0.00%+11,169New
China Universal Asset Management Co., Ltd.11,192$323.8K0.04%+4,517+67.7%Added
E Fund Management Co., Ltd.11,304$327.0K0.02%+2,347+26.2%Added
Glenmede Trust Co NA11,451$331.3K0.00%+11,451New
Franklin Street Advisors Inc11,470$332.0K0.02%−250−2.1%Reduced
Corton Capital Inc.11,819$341.9K0.13%−4,609−28.1%Reduced
Cerity Partners LLC11,926$345.0K0.00%+661+5.9%Added
King Wealth12,000$347.0K0.06%00.0%Unchanged
Obermeyer Wood Investment Counsel, LLLP12,242$354.2K0.02%+176+1.5%Added
CWM Advisors, LLC12,340$357.0K0.04%−4,442−26.5%Reduced
Arizona State Retirement System12,681$366.9K0.00%−185−1.4%Reduced
Mariner, LLC12,724$368.1K0.00%+3,470+37.5%Added
Campbell & CO Investment Adviser LLC13,763$398.2K0.03%+13,763New
ProShare Advisors LLC14,345$415.0K0.00%+1,206+9.2%Added
Principal Financial Group Inc14,369$415.7K0.00%−60−0.4%Reduced
DekaBank Deutsche Girozentrale15,800$461.0K0.00%00.0%Unchanged
Caxton Associates LP16,047$464.2K0.03%+16,047New
Graham Capital Management, L.P.18,212$526.9K0.01%+18,212New
Skandinaviska Enskilda Banken AB (publ)18,914$547.2K0.00%00.0%Unchanged
Bellevue Group AG19,146$553.9K0.01%−10,854−36.2%Reduced
Sherbrooke Park Advisers LLC20,131$582.4K0.11%+20,131New
HighVista Strategies LLC21,229$614.2K0.22%−7,130−25.1%Reduced
Y-Intercept (Hong Kong) Ltd21,449$620.5K0.05%+21,449New
Janus Henderson Group PLC21,735$628.0K0.00%+10.0%Added
Tudor Investment Corp Et Al22,510$651.2K0.01%−6,276−21.8%Reduced
New York State Common Retirement Fund23,044$666.7K0.00%−59−0.3%Reduced
Mirae Asset Global Investments Co., Ltd.29,558$692.2K0.00%−2,201−6.9%Reduced
AlphaCentric Advisors LLC25,000$723.3K0.44%−5,000−16.7%Reduced
Nebula Research & Development LLC25,446$736.2K0.16%+10,160+66.5%Added
Ensign Peak Advisors, Inc27,036$782.2K0.00%−1,364−4.8%Reduced
American International Group, Inc.28,149$814.4K0.00%−241−0.8%Reduced
Invesco Ltd.28,359$820.4K0.00%−17,404−38.0%Reduced
Group One Trading, L.P.28,363$820.5K0.03%+28,363New
MetLife Investment Management28,596$827.3K0.01%00.0%Unchanged
Wells Fargo & Company29,793$861.9K0.00%+13,636+84.4%Added
Suvretta Capital Management, LLC30,500$882.4K0.04%+30,500New
Los Angeles Capital Management LLC30,827$891.8K0.00%+21,673+236.8%Added
Polar Asset Management Partners Inc.31,400$908.4K0.02%+31,400New
Franklin Resources Inc31,844$921.2K0.00%+31,844New
Renaissance Technologies LLC32,567$942.0K0.00%−181,400−84.8%Reduced
Twinbeech Capital LP34,468$997.2K0.02%+10,307+42.7%Added
Soleus Capital Management, L.P.34,500$998.1K0.09%−48,500−58.4%Reduced
Jackson Creek Investment Advisors LLC34,712$1.00M0.36%+34,712New
Hennion & Walsh Asset Management, Inc.34,895$1.01M0.05%+849+2.5%Added
D. E. Shaw & Co., Inc.35,640$1.03M0.00%+35,640New
Profund Advisors LLC37,475$1.08M0.04%+9,585+34.4%Added
Engineers Gate Manager LP37,570$1.09M0.03%+25,048+200.0%Added
Resolute Capital Asset Partners LLC39,500$1.14M0.60%+39,500New
Alps Advisors Inc41,099$1.19M0.01%+1,027+2.6%Added
State of Wisconsin Investment Board41,486$1.20M0.00%+1,687+4.2%Added