Protagonist Therapeutics, Inc
PTGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001377121
In the last 90 days, Protagonist Therapeutics, Inc insiders filed 0 open-market purchases and 3 sales; 346 institutions reported holding it in 13F filings for Q2 2026, worth $9.30B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2022
Institutional positions in Protagonist Therapeutics, Inc as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 131
- −7 vs. Q1 2022
- Shares held
- 53.3M
- +2.76M (+5.5%) vs. Q1 2022
- Total value
- $422.1M
- −$771.0M (−64.6%) vs. Q1 2022
- New holders
- 28
- 44 more added
- Sold out
- 35
- 38 more reduced
2 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PTGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 346 | $9.30B |
| Q1 2026 | 322 | $8.31B |
| Q4 2025 | 319 | $6.18B |
| Q3 2025 | 275 | $4.70B |
| Q2 2025 | 274 | $3.92B |
| Q1 2025 | 275 | $3.15B |
| Q4 2024 | 241 | $2.44B |
| Q3 2024 | 240 | $2.78B |
| Q2 2024 | 188 | $2.05B |
| Q1 2024 | 185 | $1.73B |
| Q4 2023 | 157 | $1.32B |
| Q3 2023 | 144 | $945.9M |
| Q2 2023 | 167 | $1.57B |
| Q1 2023 | 138 | $1.22B |
| Q4 2022 | 137 | $533.3M |
| Q3 2022 | 133 | $398.9M |
| Q2 2022 | 131 | $422.1M |
| Q1 2022 | 140 | $1.19B |
| Q4 2021 | 149 | $1.68B |
| Q3 2021 | 132 | $820.8M |
| Q2 2021 | 139 | $2.16B |
| Q1 2021 | 127 | $1.15B |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Protagonist Therapeutics, Inc; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Delphia (USA) Inc. | 11,845 | $94.0K | 0.06% | +11,845 | New |
| Cerity Partners LLC | 11,640 | $92.0K | 0.00% | +11,640 | New |
| Engineers Gate Manager LP | 11,383 | $90.0K | 0.00% | −45,380−79.9% | Reduced |
| Quantamental Technologies LLC | 11,170 | $88.0K | 0.04% | +11,170 | New |
| State Board of Administration of Florida Retirement System | 10,963 | $87.0K | 0.00% | +10+0.1% | Added |
| Corton Capital Inc. | 10,836 | $86.0K | 0.08% | +10,836 | New |
| Ensign Peak Advisors, Inc | 10,680 | $84.0K | 0.00% | 00.0% | Unchanged |
| Caption Management, LLC | 10,400 | $82.0K | 0.01% | −59,600−85.1% | Reduced |
| Atom Investors LP | 10,338 | $82.0K | 0.04% | +10,338 | New |
| Allspring Global Investments Holdings, LLC | 10,312 | $81.0K | 0.00% | −16,994−62.2% | Reduced |
| Simplex Trading, LLC | 9,637 | $76.0K | 0.00% | +4,665+93.8% | Added |
| Quantbot Technologies LP | 9,658 | $76.0K | 0.01% | +9,658 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 7,199 | $57.0K | 0.00% | 00.0% | Unchanged |
| Lazard Asset Management LLC | 6,404 | $50.0K | 0.00% | +6,404 | New |
| Amalgamated Bank | 5,765 | $46.0K | 0.00% | −1,530−21.0% | Reduced |
| Wells Fargo & Company | 5,625 | $44.0K | 0.00% | −20,394−78.4% | Reduced |
| Ameritas Investment Partners, Inc. | 3,501 | $27.0K | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 2,921 | $23.1K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 2,000 | $16.0K | 0.00% | −24,390−92.4% | Reduced |
| Great West Life Assurance Co | 1,982 | $16.0K | 0.00% | 00.0% | Unchanged |
| Eagle Bay Advisors LLC | 1,000 | $7.91K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 510 | $4.00K | 0.00% | −2,490−83.0% | Reduced |
| Dark Forest Capital Management LP | 525 | $4.00K | 0.00% | +525 | New |
| Leonteq Securities AG | 470 | $3.72K | 0.00% | 00.0% | Unchanged |
| Truvestments Capital LLC | 345 | $3.00K | 0.00% | +345 | New |
| Macquarie Group Ltd | 307 | $2.00K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 163 | $1.00K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 9 | $0 | 0.00% | −2−18.2% | Reduced |
| Lindbrook Capital, LLC | 26 | $0 | 0.00% | +26 | New |
| International Biotechnology Trust PLC | 128 | – | – | +128 | New |
| Federated Hermes, Inc. | 28 | – | – | +28 | New |
| Artal Group S.A. | 0 | $0 | 0.00% | −800,100−100.0% | Sold out |
| Tri Locum Partners LP | 0 | $0 | 0.00% | −769,250−100.0% | Sold out |
| Fairmount Funds Management LLC | 0 | $0 | 0.00% | −549,988−100.0% | Sold out |
| Sofinnova Investments, Inc. | 0 | $0 | 0.00% | −547,441−100.0% | Sold out |
| Altium Capital Management LP | 0 | $0 | 0.00% | −386,000−100.0% | Sold out |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −381,711−100.0% | Sold out |
| Commodore Capital LP | 0 | $0 | 0.00% | −331,886−100.0% | Sold out |
| Polar Capital Holdings Plc | 0 | $0 | 0.00% | −303,429−100.0% | Sold out |
| Price T Rowe Associates Inc | 0 | $0 | 0.00% | −300,468−100.0% | Sold out |
| Affinity Asset Advisors, LLC | 0 | $0 | 0.00% | −300,000−100.0% | Sold out |
| Lord, Abbett & Co. LLC | 0 | $0 | 0.00% | −275,787−100.0% | Sold out |
| Sessa Capital IM, L.P. | 0 | $0 | 0.00% | −257,000−100.0% | Sold out |
| Opaleye Management Inc. | 0 | $0 | 0.00% | −251,500−100.0% | Sold out |
| Twin Lakes Capital Management, LLC | 0 | $0 | 0.00% | −139,397−100.0% | Sold out |
| Candriam Luxembourg S.C.A. | 0 | $0 | 0.00% | −83,646−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −81,873−100.0% | Sold out |
| Pura Vida Investments, LLC | 0 | $0 | 0.00% | −65,371−100.0% | Sold out |
| Industrial Alliance Investment Management Inc. | 0 | $0 | 0.00% | −56,695−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −22,993−100.0% | Sold out |
| Maven Securities LTD | 0 | $0 | 0.00% | −19,700−100.0% | Sold out |
| TD Asset Management Inc | 0 | $0 | 0.00% | −17,842−100.0% | Sold out |
| ProShare Advisors LLC | 0 | $0 | 0.00% | −13,399−100.0% | Sold out |
| Harvest Investment Services, LLC | 0 | $0 | 0.00% | −13,362−100.0% | Sold out |
| Arizona State Retirement System | 0 | $0 | 0.00% | −11,612−100.0% | Sold out |
| Parametrica Management Ltd | 0 | $0 | 0.00% | −11,156−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −9,795−100.0% | Sold out |
| Gladstone Institutional Advisory LLC | 0 | $0 | 0.00% | −9,630−100.0% | Sold out |
| Teacher Retirement System of Texas | 0 | $0 | 0.00% | −8,927−100.0% | Sold out |
| Point72 Hong Kong Ltd | 0 | $0 | 0.00% | −5,704−100.0% | Sold out |
| Kessler Investment Group, LLC | 0 | $0 | 0.00% | −5,165−100.0% | Sold out |
| Amundi | 0 | $0 | 0.00% | −3,855−100.0% | Sold out |
| Cutler Group LP | 0 | $0 | 0.00% | −784−100.0% | Sold out |
| US Bancorp | 0 | $0 | 0.00% | −470−100.0% | Sold out |
| Signaturefd, LLC | 0 | $0 | 0.00% | −78−100.0% | Sold out |
| Advisor Group Holdings, Inc. | 0 | $0 | 0.00% | −57−100.0% | Sold out |
| Parametric Portfolio Associates LLC | – | – | – | – | Not filed |
| Amalgamated Financial Corp. | – | – | – | – | Not filed |